3GTME

Co-complex of backtracked rna polymerase ii with tfiis
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription, transferase/dna-rna hybrid
source organism Saccharomyces cerevisiae
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 45
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3gtmE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3gtmE02
3HOVE 4BBRE 2WB1H 4A3KE 3S2HE 4A3FE 2NVYE 2NVXE 4QIWH 3S1RE 4A3CE 3HOWE 3M3YE 4A3DE 2PMZH 2Y0SH 2JA8E 3GTLE 3GTGE 3FKIE 5IYBE 5M3FE 2E2IE 5C4XE 1Y1WE 3H3VF 2NVTE 4A3GE 3CQZE 3I4ME 4BXXE 3GTOE 4C3JE 2NVQE 2JA5E 2VUME 1TWCE 2R93E 4C3IE 4A3JE 1I50E 1TWHE 2E2HE 5FJ8E 2E2JE 4C2ME 3PO2E 1DZFA 2WAQH 3RZDE 2B63E 4C3HE 2JA7E 1I6HE 3S2DE 5IP9E 1EIKA 4A3LE 3GTKE 3HOUE 4BY1E 3S15E 3S1NE 4A3ME 2YU9E 1K83E 4AYBH 4Y52E 3HOYE 3GTJE 5M5XE 3S14E 1I3QE 3RZOE 3K7AE 3S1ME 5IYCE 5FLME 5IYDE 3S1QE 3I4NE 2R7ZE 3H0GE 5M3ME 1WCME 3HOXE 3GTPE 3M4OE 4X6AE 2R92E 3HKZH 3S16E 4BY7E 5C44E 4A93E 4Y7NE 3S17E 4A3EE 2JA6E 3GTME 4BBSE 4A3IE 1SFOE 5M5YE 3HOZE 5C3EE 1TWGE 1TWAE 1Y1VE 3PO3E 1TWFE 1R9TE 5C4JE 3GTQE 4A3BE 5M5WE 5IP7E
chains in the Genus database with same CATH superfamily
2JA5F 2VUMF 4GZYE 3HOVE 2A6HE 1TWCF 2R93F 4C3IF 4A3JF 4BBRE 2WB1H 1I50F 4A3KE 4MEYE 2NVXF 2O5JE 3S1RF 1TWHF 2E2HF 5FJ8F 3S2HE 4A3FE 2NVYE 2NVXE 4QIWH 3S1RE 3PO2F 4A3CE 3RZDF 3HOWE 4C3HF 4KN7E 5C4XF 3M3YE 4A3DE 2PMZH 2Y0SH 2JA7F 2A68E 2JA8E 3GTLE 4AYBK 1I6HF 2NVTF 3GTGE 3FKIE 5IYBE 5M3FE 2E2IE 5C4XE 5IP9F 1Y1WE 3H3VF 1YNNK 4A3LF 2BE5E 2NVTE 4XSZE 4G7ZE 3EQLE 4OIQE 3HOUF 1I6VE 3S15F 4MQ9E 4XLNE 1K83F 4A3GE 3CQZE 3I4ME 4BXXE 2WAQK 3GTOE 4Y52F 4C3JE 2NVQE 2JA5E 2VUME 4G7OE 3GTJF 1TWCE 2R93E 1I3QF 5M5XF 4C3IE 3RZOF 4A3JE 2PPBE 3K7AF 3S1MF 2E2JF 1I50E 4C2MF 5FLMF 5IYDF 4OIOE 3HKZK 1TWHE 3S1QF 2E2HE 5FJ8E 2E2JE 4C2ME 2R7ZF 3H0GF 5M3MF 4YFNE 3PO2E 1DZFA 2WAQH 2B63F 4KN4E 1IW7E 1HQME 2KRXA 3GTPF 3M4OF 3RZDE 4X6AF 2B63E 2R92F 3S2DF 4C3HE 4XSXE 5D4CE 2JA7E 3S16F 4BY7F 5C44F 1I6HE 4Y7NF 3GTKF 4BY1F 4A3EF 3S2DE 5TMFE 5IP9E 3S17F 2JA6F 3S1NF 4A3MF 1EIKA 2YU9F 3GTMF 4A3LE 4BBSF 3GTKE 3HOUE 4BY1E 3S15E 4YFKE 4Q4ZE 3S1NE 1SFOF 4A3ME 5M5YF 3HOZF 2YU9E 5C3EF 1K83E 3HOYF 4XLPE 4AYBH 4Y52E 3S14F 3HOYE 1TWAF 1TWGF 5IYCF 1Y1VF 3GTJE 3PO3F 5M5XE 3S14E 1I3QE 4G7HE 1R9TF 3RZOE 5C4JF 3GTQF 3I4NF 3K7AE 4A3BF 3S1ME 5IYCE 2WB1I 5M5WF 5FLME 4JK1E 5IP7F 5IYDE 4LLGE 4OINE 3S1QE 1WCMF 5D4EE 3I4NE 2R7ZE 3HOXF 3H0GE 5M3ME 4Q5SE 4OIRE 5TMCE 3HOVF 1WCME 4BBRF 4LK0E 2A69E 1SMYE 3HOXE 3GTPE 3M4OE 4LK1E 4OIPE 4A3KF 4A93F 4X6AE 2R92E 2PMZK 3HKZH 3S2HF 2Y0SI 4A3FF 3S16E 2NVYF 4KMUE 4BY7E 5C44E 4A93E 4YG2E 4Y7NE 5BYHE 3S17E 4A3EE 4ZH4E 4A3IF 4YFXE 2JA6E 4A3CF 4LJZE 1YNJK 3GTME 4BBSE 3WODE 3HOWF 4A3IE 3DXJE 1SFOE 5M5YE 3HOZE 5C3EE 1ZYRE 3M3YF 4A3DF 2JA8F 3GTLF 3GTGF 3H3VG 5D4DE 1TWFF 3FKIF 5IYBF 5E18E 5M3FF 2E2IF 1Y1WF 2CW0E 4MEXE 1TWGE 1TWAE 2O5IE 1Y1VE 3PO3E 5IPLE 1TWFE 1R9TE 5C4JE 3GTQE 4A3BE 4QIWK 3CQZF 5M5WE 4A3GF 3I4MF 5IP7E 5E17E 4BXXF 1QKLA 3GTOF 2A6EE 4C3JF 2NVQF
chains in the Genus database with same CATH topology
3HOVE 4BBRE 2WB1H 4A3KE 3S2HE 4A3FE 2NVYE 2NVXE 4QIWH 3S1RE 4A3CE 3HOWE 3M3YE 4A3DE 2PMZH 2Y0SH 2JA8E 3GTLE 3GTGE 3FKIE 5IYBE 5M3FE 2E2IE 5C4XE 1Y1WE 3H3VF 2NVTE 4A3GE 3CQZE 3I4ME 4BXXE 3GTOE 4C3JE 2NVQE 2JA5E 2VUME 1TWCE 2R93E 4C3IE 4A3JE 1I50E 1TWHE 2E2HE 5FJ8E 2E2JE 4C2ME 3PO2E 1DZFA 2WAQH 3RZDE 2B63E 4C3HE 2JA7E 1I6HE 3S2DE 5IP9E 1EIKA 4A3LE 3GTKE 3HOUE 4BY1E 3S15E 3S1NE 4A3ME 2YU9E 1K83E 4AYBH 4Y52E 3HOYE 3GTJE 5M5XE 3S14E 1I3QE 3RZOE 3K7AE 3S1ME 5IYCE 5FLME 5IYDE 3S1QE 3I4NE 2R7ZE 3H0GE 5M3ME 1WCME 3HOXE 3GTPE 3M4OE 4X6AE 2R92E 3HKZH 3S16E 4BY7E 5C44E 4A93E 4Y7NE 3S17E 4A3EE 2JA6E 3GTME 4BBSE 4A3IE 1SFOE 5M5YE 3HOZE 5C3EE 1TWGE 1TWAE 1Y1VE 3PO3E 1TWFE 1R9TE 5C4JE 3GTQE 4A3BE 5M5WE 5IP7E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOV E;  4BBR E;  2WB1 H;  4A3K E;  3S2H E;  4A3F E;  2NVY E;  2NVX E;  4QIW H;  3S1R E;  4A3C E;  3HOW E;  3M3Y E;  4A3D E;  2PMZ H;  2Y0S H;  2JA8 E;  3GTL E;  3GTG E;  3FKI E;  5IYB E;  5M3F E;  2E2I E;  5C4X E;  1Y1W E;  3H3V F;  2NVT E;  4A3G E;  3CQZ E;  3I4M E;  4BXX E;  3GTO E;  4C3J E;  2NVQ E;  2JA5 E;  2VUM E;  1TWC E;  2R93 E;  4C3I E;  4A3J E;  1I50 E;  1TWH E;  2E2H E;  5FJ8 E;  2E2J E;  4C2M E;  3PO2 E;  1DZF A;  2WAQ H;  3RZD E;  2B63 E;  4C3H E;  2JA7 E;  1I6H E;  3S2D E;  5IP9 E;  1EIK A;  4A3L E;  3GTK E;  3HOU E;  4BY1 E;  3S15 E;  3S1N E;  4A3M E;  2YU9 E;  1K83 E;  4AYB H;  4Y52 E;  3HOY E;  3GTJ E;  5M5X E;  3S14 E;  1I3Q E;  3RZO E;  3K7A E;  3S1M E;  5IYC E;  5FLM E;  5IYD E;  3S1Q E;  3I4N E;  2R7Z E;  3H0G E;  5M3M E;  1WCM E;  3HOX E;  3GTP E;  3M4O E;  4X6A E;  2R92 E;  3HKZ H;  3S16 E;  4BY7 E;  5C44 E;  4A93 E;  4Y7N E;  3S17 E;  4A3E E;  2JA6 E;  3GTM E;  4BBS E;  4A3I E;  1SFO E;  5M5Y E;  3HOZ E;  5C3E E;  1TWG E;  1TWA E;  1Y1V E;  3PO3 E;  1TWF E;  1R9T E;  5C4J E;  3GTQ E;  4A3B E;  5M5W E;  5IP7 E; 
#chains in the Genus database with same CATH topology
 2JA5 F;  2VUM F;  4GZY E;  3HOV E;  2A6H E;  1TWC F;  2R93 F;  4C3I F;  4A3J F;  4BBR E;  2WB1 H;  1I50 F;  4A3K E;  4MEY E;  2NVX F;  2O5J E;  3S1R F;  1TWH F;  2E2H F;  5FJ8 F;  3S2H E;  4A3F E;  2NVY E;  2NVX E;  4QIW H;  3S1R E;  3PO2 F;  4A3C E;  3RZD F;  3HOW E;  4C3H F;  4KN7 E;  5C4X F;  3M3Y E;  4A3D E;  2PMZ H;  2Y0S H;  2JA7 F;  2A68 E;  2JA8 E;  3GTL E;  4AYB K;  1I6H F;  2NVT F;  3GTG E;  3FKI E;  5IYB E;  5M3F E;  2E2I E;  5C4X E;  5IP9 F;  1Y1W E;  3H3V F;  1YNN K;  4A3L F;  2BE5 E;  2NVT E;  4XSZ E;  4G7Z E;  3EQL E;  4OIQ E;  3HOU F;  1I6V E;  3S15 F;  4MQ9 E;  4XLN E;  1K83 F;  4A3G E;  3CQZ E;  3I4M E;  4BXX E;  2WAQ K;  3GTO E;  4Y52 F;  4C3J E;  2NVQ E;  2JA5 E;  2VUM E;  4G7O E;  3GTJ F;  1TWC E;  2R93 E;  1I3Q F;  5M5X F;  4C3I E;  3RZO F;  4A3J E;  2PPB E;  3K7A F;  3S1M F;  2E2J F;  1I50 E;  4C2M F;  5FLM F;  5IYD F;  4OIO E;  3HKZ K;  1TWH E;  3S1Q F;  2E2H E;  5FJ8 E;  2E2J E;  4C2M E;  2R7Z F;  3H0G F;  5M3M F;  4YFN E;  3PO2 E;  1DZF A;  2WAQ H;  2B63 F;  4KN4 E;  1IW7 E;  1HQM E;  2KRX A;  3GTP F;  3M4O F;  3RZD E;  4X6A F;  2B63 E;  2R92 F;  3S2D F;  4C3H E;  4XSX E;  5D4C E;  2JA7 E;  3S16 F;  4BY7 F;  5C44 F;  1I6H E;  4Y7N F;  3GTK F;  4BY1 F;  4A3E F;  3S2D E;  5TMF E;  5IP9 E;  3S17 F;  2JA6 F;  3S1N F;  4A3M F;  1EIK A;  2YU9 F;  3GTM F;  4A3L E;  4BBS F;  3GTK E;  3HOU E;  4BY1 E;  3S15 E;  4YFK E;  4Q4Z E;  3S1N E;  1SFO F;  4A3M E;  5M5Y F;  3HOZ F;  2YU9 E;  5C3E F;  1K83 E;  3HOY F;  4XLP E;  4AYB H;  4Y52 E;  3S14 F;  3HOY E;  1TWA F;  1TWG F;  5IYC F;  1Y1V F;  3GTJ E;  3PO3 F;  5M5X E;  3S14 E;  1I3Q E;  4G7H E;  1R9T F;  3RZO E;  5C4J F;  3GTQ F;  3I4N F;  3K7A E;  4A3B F;  3S1M E;  5IYC E;  2WB1 I;  5M5W F;  5FLM E;  4JK1 E;  5IP7 F;  5IYD E;  4LLG E;  4OIN E;  3S1Q E;  1WCM F;  5D4E E;  3I4N E;  2R7Z E;  3HOX F;  3H0G E;  5M3M E;  4Q5S E;  4OIR E;  5TMC E;  3HOV F;  1WCM E;  4BBR F;  4LK0 E;  2A69 E;  1SMY E;  3HOX E;  3GTP E;  3M4O E;  4LK1 E;  4OIP E;  4A3K F;  4A93 F;  4X6A E;  2R92 E;  2PMZ K;  3HKZ H;  3S2H F;  2Y0S I;  4A3F F;  3S16 E;  2NVY F;  4KMU E;  4BY7 E;  5C44 E;  4A93 E;  4YG2 E;  4Y7N E;  5BYH E;  3S17 E;  4A3E E;  4ZH4 E;  4A3I F;  4YFX E;  2JA6 E;  4A3C F;  4LJZ E;  1YNJ K;  3GTM E;  4BBS E;  3WOD E;  3HOW F;  4A3I E;  3DXJ E;  1SFO E;  5M5Y E;  3HOZ E;  5C3E E;  1ZYR E;  3M3Y F;  4A3D F;  2JA8 F;  3GTL F;  3GTG F;  3H3V G;  5D4D E;  1TWF F;  3FKI F;  5IYB F;  5E18 E;  5M3F F;  2E2I F;  1Y1W F;  2CW0 E;  4MEX E;  1TWG E;  1TWA E;  2O5I E;  1Y1V E;  3PO3 E;  5IPL E;  1TWF E;  1R9T E;  5C4J E;  3GTQ E;  4A3B E;  4QIW K;  3CQZ F;  5M5W E;  4A3G F;  3I4M F;  5IP7 E;  5E17 E;  4BXX F;  1QKL A;  3GTO F;  2A6E E;  4C3J F;  2NVQ F; 
#chains in the Genus database with same CATH homology
 3HOV E;  4BBR E;  2WB1 H;  4A3K E;  3S2H E;  4A3F E;  2NVY E;  2NVX E;  4QIW H;  3S1R E;  4A3C E;  3HOW E;  3M3Y E;  4A3D E;  2PMZ H;  2Y0S H;  2JA8 E;  3GTL E;  3GTG E;  3FKI E;  5IYB E;  5M3F E;  2E2I E;  5C4X E;  1Y1W E;  3H3V F;  2NVT E;  4A3G E;  3CQZ E;  3I4M E;  4BXX E;  3GTO E;  4C3J E;  2NVQ E;  2JA5 E;  2VUM E;  1TWC E;  2R93 E;  4C3I E;  4A3J E;  1I50 E;  1TWH E;  2E2H E;  5FJ8 E;  2E2J E;  4C2M E;  3PO2 E;  1DZF A;  2WAQ H;  3RZD E;  2B63 E;  4C3H E;  2JA7 E;  1I6H E;  3S2D E;  5IP9 E;  1EIK A;  4A3L E;  3GTK E;  3HOU E;  4BY1 E;  3S15 E;  3S1N E;  4A3M E;  2YU9 E;  1K83 E;  4AYB H;  4Y52 E;  3HOY E;  3GTJ E;  5M5X E;  3S14 E;  1I3Q E;  3RZO E;  3K7A E;  3S1M E;  5IYC E;  5FLM E;  5IYD E;  3S1Q E;  3I4N E;  2R7Z E;  3H0G E;  5M3M E;  1WCM E;  3HOX E;  3GTP E;  3M4O E;  4X6A E;  2R92 E;  3HKZ H;  3S16 E;  4BY7 E;  5C44 E;  4A93 E;  4Y7N E;  3S17 E;  4A3E E;  2JA6 E;  3GTM E;  4BBS E;  4A3I E;  1SFO E;  5M5Y E;  3HOZ E;  5C3E E;  1TWG E;  1TWA E;  1Y1V E;  3PO3 E;  1TWF E;  1R9T E;  5C4J E;  3GTQ E;  4A3B E;  5M5W E;  5IP7 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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