3GTPE

Backtracked rna polymerase ii complex with 24mer rna
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription, transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3gtpE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3gtpE02
4A93E 1I50E 4BY7E 5IYCE 3S17E 4A3DE 3I4NE 5M5YE 5C4XE 3S16E 1R9TE 3HKZH 5C3EE 3S1QE 3S1RE 1Y1VE 3RZDE 5M5WE 4A3EE 1K83E 4BXXE 4A3BE 4A3GE 2E2HE 5IP7E 1TWFE 3GTLE 4A3ME 2NVQE 1DZFA 3PO3E 2Y0SH 3GTGE 1WCME 4AYBH 4Y52E 4Y7NE 2R92E 3GTJE 2NVYE 3HOYE 1I3QE 2R93E 1TWGE 5FJ8E 2YU9E 2WB1H 3HOXE 2E2JE 3S15E 3H0GE 2R7ZE 3S14E 4BY1E 2JA7E 2JA5E 2JA6E 3CQZE 1SFOE 5M3ME 3PO2E 3S1NE 4X6AE 3FKIE 3HOUE 3M3YE 3S2DE 3GTPE 3HOVE 4A3JE 4A3FE 4C2ME 1EIKA 3GTOE 2PMZH 4C3JE 5IP9E 1TWAE 4BBSE 3H3VF 4A3KE 2JA8E 4C3HE 3HOWE 5FLME 4C3IE 3S2HE 1Y1WE 5IYBE 3M4OE 5IYDE 3GTME 2NVXE 5C44E 5M5XE 2B63E 4A3LE 3HOZE 4A3CE 3RZOE 3GTKE 1I6HE 2VUME 3GTQE 4BBRE 2NVTE 4QIWH 4A3IE 3K7AE 2E2IE 5C4JE 1TWHE 2WAQH 3I4ME 3S1ME 5M3FE 1TWCE
chains in the Genus database with same CATH superfamily
5M5WF 4A93E 1I50E 4A3EF 1K83F 4BY7E 4KMUE 4XSXE 4BXXF 4A3BF 4A3GF 5IYCE 3S17E 3HKZK 4JK1E 2E2HF 4Q5SE 5IP7F 4A3DE 1TWFF 5TMFE 3GTLF 4A3MF 4BY7F 2NVQF 3I4NE 5M5YE 5C4XE 3PO3F 4G7OE 4ZH4E 3S16E 5IYCF 1R9TE 4GZYE 3HKZH 5C3EE 3GTGF 3S1QE 1WCMF 5E18E 4LK1E 3S1RE 4Y52F 4Y7NF 2R92F 3GTJF 1Y1VE 3RZDE 5M5WE 2NVYF 1R9TF 3HOYF 4A3EE 1K83E 2R93F 1TWGF 5D4EE 5FJ8F 2YU9F 3HOXF 4BXXE 4A3BE 4A3GE 1I6VE 2E2JF 2JA8F 5D4DE 3S15F 2E2HE 5IP7E 3H0GF 1TWFE 3GTLE 4A3ME 2NVQE 2R7ZF 1DZFA 3S14F 3PO3E 2O5IE 3DXJE 4BY1F 2JA7F 2Y0SH 3WODE 3GTGE 2JA5F 2JA6F 3CQZF 1SFOF 1WCME 4AYBH 5M3MF 3PO2F 3S1NF 4Y52E 4X6AF 4Y7NE 3FKIF 2R92E 3GTJE 2NVYE 3HOYE 4OIOE 1I3QE 2R93E 1YNNK 3HOUF 1TWGE 5FJ8E 2YU9E 2WB1H 3HOXE 4YFNE 4OIRE 3M3YF 3S2DF 2E2JE 3GTPF 3HOVF 3S15E 4LJZE 3H0GE 4A3FF 4C2MF 1I3QF 2R7ZE 3S14E 4C3JF 5IP9F 1TWAF 4BY1E 4BBSF 2JA7E 4XSZE 2A68E 2JA5E 2JA6E 2Y0SI 3CQZE 4LK0E 4MQ9E 4A3KF 4G7ZE 1SFOE 2A6EE 2CW0E 4AYBK 4C3HF 4MEYE 4OIQE 5M3ME 3HOWF 3PO2E 3S1NE 5C4XF 4X6AE 5FLMF 3FKIE 4C3IF 3S2HF 1YNJK 1Y1WF 3HOUE 2PMZK 5BYHE 4OINE 3EQLE 5IYBF 5TMCE 5IYDF 3M4OF 3M3YE 3S2DE 3GTMF 3GTPE 3HOVE 4A3JE 2NVXF 5C44F 5M5XF 5IPLE 4XLNE 2B63F 1SMYE 4A3LF 3HOZF 4A3CF 4A3FE 1ZYRE 4C2ME 1EIKA 3RZOF 3GTOE 2PMZH 4C3JE 5IP9E 3GTKF 1TWAE 1I6HF 2VUMF 4BBSE 3H3VF 2A69E 4KN7E 4A3JF 2PPBE 3GTQF 4BBRF 4A3KE 2JA8E 2NVTF 4A3IF 4C3HE 3K7AF 2E2IF 3HOWE 4YG2E 3GTOF 4KN4E 5FLME 2A6HE 4C3IE 3S2HE 5C4JF 1IW7E 1TWHF 1Y1WE 3I4MF 3S1MF 5M3FF 1QKLA 5IYBE 3M4OE 5IYDE 1TWCF 3GTME 4G7HE 2NVXE 4YFXE 1I50F 5C44E 4A93F 5M5XE 2B63E 4QIWK 4A3LE 3HOZE 4A3CE 4Q4ZE 4LLGE 3RZOE 3S17F 3GTKE 1I6HE 2VUME 2WB1I 2O5JE 2WAQK 3GTQE 1HQME 4A3DF 4BBRE 2NVTE 3I4NF 4QIWH 4A3IE 4OIPE 3K7AE 5M5YF 2KRXA 2E2IE 4MEXE 3S16F 4XLPE 4YFKE 3H3VG 5C3EF 5C4JE 5D4CE 3S1QF 1TWHE 2WAQH 3I4ME 2BE5E 3S1RF 3S1ME 5M3FE 3RZDF 1TWCE 5E17E 1Y1VF
chains in the Genus database with same CATH topology
4A93E 1I50E 4BY7E 5IYCE 3S17E 4A3DE 3I4NE 5M5YE 5C4XE 3S16E 1R9TE 3HKZH 5C3EE 3S1QE 3S1RE 1Y1VE 3RZDE 5M5WE 4A3EE 1K83E 4BXXE 4A3BE 4A3GE 2E2HE 5IP7E 1TWFE 3GTLE 4A3ME 2NVQE 1DZFA 3PO3E 2Y0SH 3GTGE 1WCME 4AYBH 4Y52E 4Y7NE 2R92E 3GTJE 2NVYE 3HOYE 1I3QE 2R93E 1TWGE 5FJ8E 2YU9E 2WB1H 3HOXE 2E2JE 3S15E 3H0GE 2R7ZE 3S14E 4BY1E 2JA7E 2JA5E 2JA6E 3CQZE 1SFOE 5M3ME 3PO2E 3S1NE 4X6AE 3FKIE 3HOUE 3M3YE 3S2DE 3GTPE 3HOVE 4A3JE 4A3FE 4C2ME 1EIKA 3GTOE 2PMZH 4C3JE 5IP9E 1TWAE 4BBSE 3H3VF 4A3KE 2JA8E 4C3HE 3HOWE 5FLME 4C3IE 3S2HE 1Y1WE 5IYBE 3M4OE 5IYDE 3GTME 2NVXE 5C44E 5M5XE 2B63E 4A3LE 3HOZE 4A3CE 3RZOE 3GTKE 1I6HE 2VUME 3GTQE 4BBRE 2NVTE 4QIWH 4A3IE 3K7AE 2E2IE 5C4JE 1TWHE 2WAQH 3I4ME 3S1ME 5M3FE 1TWCE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A93 E;  1I50 E;  4BY7 E;  5IYC E;  3S17 E;  4A3D E;  3I4N E;  5M5Y E;  5C4X E;  3S16 E;  1R9T E;  3HKZ H;  5C3E E;  3S1Q E;  3S1R E;  1Y1V E;  3RZD E;  5M5W E;  4A3E E;  1K83 E;  4BXX E;  4A3B E;  4A3G E;  2E2H E;  5IP7 E;  1TWF E;  3GTL E;  4A3M E;  2NVQ E;  1DZF A;  3PO3 E;  2Y0S H;  3GTG E;  1WCM E;  4AYB H;  4Y52 E;  4Y7N E;  2R92 E;  3GTJ E;  2NVY E;  3HOY E;  1I3Q E;  2R93 E;  1TWG E;  5FJ8 E;  2YU9 E;  2WB1 H;  3HOX E;  2E2J E;  3S15 E;  3H0G E;  2R7Z E;  3S14 E;  4BY1 E;  2JA7 E;  2JA5 E;  2JA6 E;  3CQZ E;  1SFO E;  5M3M E;  3PO2 E;  3S1N E;  4X6A E;  3FKI E;  3HOU E;  3M3Y E;  3S2D E;  3GTP E;  3HOV E;  4A3J E;  4A3F E;  4C2M E;  1EIK A;  3GTO E;  2PMZ H;  4C3J E;  5IP9 E;  1TWA E;  4BBS E;  3H3V F;  4A3K E;  2JA8 E;  4C3H E;  3HOW E;  5FLM E;  4C3I E;  3S2H E;  1Y1W E;  5IYB E;  3M4O E;  5IYD E;  3GTM E;  2NVX E;  5C44 E;  5M5X E;  2B63 E;  4A3L E;  3HOZ E;  4A3C E;  3RZO E;  3GTK E;  1I6H E;  2VUM E;  3GTQ E;  4BBR E;  2NVT E;  4QIW H;  4A3I E;  3K7A E;  2E2I E;  5C4J E;  1TWH E;  2WAQ H;  3I4M E;  3S1M E;  5M3F E;  1TWC E; 
#chains in the Genus database with same CATH topology
 5M5W F;  4A93 E;  1I50 E;  4A3E F;  1K83 F;  4BY7 E;  4KMU E;  4XSX E;  4BXX F;  4A3B F;  4A3G F;  5IYC E;  3S17 E;  3HKZ K;  4JK1 E;  2E2H F;  4Q5S E;  5IP7 F;  4A3D E;  1TWF F;  5TMF E;  3GTL F;  4A3M F;  4BY7 F;  2NVQ F;  3I4N E;  5M5Y E;  5C4X E;  3PO3 F;  4G7O E;  4ZH4 E;  3S16 E;  5IYC F;  1R9T E;  4GZY E;  3HKZ H;  5C3E E;  3GTG F;  3S1Q E;  1WCM F;  5E18 E;  4LK1 E;  3S1R E;  4Y52 F;  4Y7N F;  2R92 F;  3GTJ F;  1Y1V E;  3RZD E;  5M5W E;  2NVY F;  1R9T F;  3HOY F;  4A3E E;  1K83 E;  2R93 F;  1TWG F;  5D4E E;  5FJ8 F;  2YU9 F;  3HOX F;  4BXX E;  4A3B E;  4A3G E;  1I6V E;  2E2J F;  2JA8 F;  5D4D E;  3S15 F;  2E2H E;  5IP7 E;  3H0G F;  1TWF E;  3GTL E;  4A3M E;  2NVQ E;  2R7Z F;  1DZF A;  3S14 F;  3PO3 E;  2O5I E;  3DXJ E;  4BY1 F;  2JA7 F;  2Y0S H;  3WOD E;  3GTG E;  2JA5 F;  2JA6 F;  3CQZ F;  1SFO F;  1WCM E;  4AYB H;  5M3M F;  3PO2 F;  3S1N F;  4Y52 E;  4X6A F;  4Y7N E;  3FKI F;  2R92 E;  3GTJ E;  2NVY E;  3HOY E;  4OIO E;  1I3Q E;  2R93 E;  1YNN K;  3HOU F;  1TWG E;  5FJ8 E;  2YU9 E;  2WB1 H;  3HOX E;  4YFN E;  4OIR E;  3M3Y F;  3S2D F;  2E2J E;  3GTP F;  3HOV F;  3S15 E;  4LJZ E;  3H0G E;  4A3F F;  4C2M F;  1I3Q F;  2R7Z E;  3S14 E;  4C3J F;  5IP9 F;  1TWA F;  4BY1 E;  4BBS F;  2JA7 E;  4XSZ E;  2A68 E;  2JA5 E;  2JA6 E;  2Y0S I;  3CQZ E;  4LK0 E;  4MQ9 E;  4A3K F;  4G7Z E;  1SFO E;  2A6E E;  2CW0 E;  4AYB K;  4C3H F;  4MEY E;  4OIQ E;  5M3M E;  3HOW F;  3PO2 E;  3S1N E;  5C4X F;  4X6A E;  5FLM F;  3FKI E;  4C3I F;  3S2H F;  1YNJ K;  1Y1W F;  3HOU E;  2PMZ K;  5BYH E;  4OIN E;  3EQL E;  5IYB F;  5TMC E;  5IYD F;  3M4O F;  3M3Y E;  3S2D E;  3GTM F;  3GTP E;  3HOV E;  4A3J E;  2NVX F;  5C44 F;  5M5X F;  5IPL E;  4XLN E;  2B63 F;  1SMY E;  4A3L F;  3HOZ F;  4A3C F;  4A3F E;  1ZYR E;  4C2M E;  1EIK A;  3RZO F;  3GTO E;  2PMZ H;  4C3J E;  5IP9 E;  3GTK F;  1TWA E;  1I6H F;  2VUM F;  4BBS E;  3H3V F;  2A69 E;  4KN7 E;  4A3J F;  2PPB E;  3GTQ F;  4BBR F;  4A3K E;  2JA8 E;  2NVT F;  4A3I F;  4C3H E;  3K7A F;  2E2I F;  3HOW E;  4YG2 E;  3GTO F;  4KN4 E;  5FLM E;  2A6H E;  4C3I E;  3S2H E;  5C4J F;  1IW7 E;  1TWH F;  1Y1W E;  3I4M F;  3S1M F;  5M3F F;  1QKL A;  5IYB E;  3M4O E;  5IYD E;  1TWC F;  3GTM E;  4G7H E;  2NVX E;  4YFX E;  1I50 F;  5C44 E;  4A93 F;  5M5X E;  2B63 E;  4QIW K;  4A3L E;  3HOZ E;  4A3C E;  4Q4Z E;  4LLG E;  3RZO E;  3S17 F;  3GTK E;  1I6H E;  2VUM E;  2WB1 I;  2O5J E;  2WAQ K;  3GTQ E;  1HQM E;  4A3D F;  4BBR E;  2NVT E;  3I4N F;  4QIW H;  4A3I E;  4OIP E;  3K7A E;  5M5Y F;  2KRX A;  2E2I E;  4MEX E;  3S16 F;  4XLP E;  4YFK E;  3H3V G;  5C3E F;  5C4J E;  5D4C E;  3S1Q F;  1TWH E;  2WAQ H;  3I4M E;  2BE5 E;  3S1R F;  3S1M E;  5M3F E;  3RZD F;  1TWC E;  5E17 E;  1Y1V F; 
#chains in the Genus database with same CATH homology
 4A93 E;  1I50 E;  4BY7 E;  5IYC E;  3S17 E;  4A3D E;  3I4N E;  5M5Y E;  5C4X E;  3S16 E;  1R9T E;  3HKZ H;  5C3E E;  3S1Q E;  3S1R E;  1Y1V E;  3RZD E;  5M5W E;  4A3E E;  1K83 E;  4BXX E;  4A3B E;  4A3G E;  2E2H E;  5IP7 E;  1TWF E;  3GTL E;  4A3M E;  2NVQ E;  1DZF A;  3PO3 E;  2Y0S H;  3GTG E;  1WCM E;  4AYB H;  4Y52 E;  4Y7N E;  2R92 E;  3GTJ E;  2NVY E;  3HOY E;  1I3Q E;  2R93 E;  1TWG E;  5FJ8 E;  2YU9 E;  2WB1 H;  3HOX E;  2E2J E;  3S15 E;  3H0G E;  2R7Z E;  3S14 E;  4BY1 E;  2JA7 E;  2JA5 E;  2JA6 E;  3CQZ E;  1SFO E;  5M3M E;  3PO2 E;  3S1N E;  4X6A E;  3FKI E;  3HOU E;  3M3Y E;  3S2D E;  3GTP E;  3HOV E;  4A3J E;  4A3F E;  4C2M E;  1EIK A;  3GTO E;  2PMZ H;  4C3J E;  5IP9 E;  1TWA E;  4BBS E;  3H3V F;  4A3K E;  2JA8 E;  4C3H E;  3HOW E;  5FLM E;  4C3I E;  3S2H E;  1Y1W E;  5IYB E;  3M4O E;  5IYD E;  3GTM E;  2NVX E;  5C44 E;  5M5X E;  2B63 E;  4A3L E;  3HOZ E;  4A3C E;  3RZO E;  3GTK E;  1I6H E;  2VUM E;  3GTQ E;  4BBR E;  2NVT E;  4QIW H;  4A3I E;  3K7A E;  2E2I E;  5C4J E;  1TWH E;  2WAQ H;  3I4M E;  3S1M E;  5M3F E;  1TWC E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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