3HOUE

Complete rna polymerase ii elongation complex i with a t-u mismatch
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 57
structure length 214
sequence length 214
chains with identical sequence Q
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3houE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3houE02
2B63E 4C2ME 3GTJE 5M3ME 1I50E 3HOUE 1Y1VE 5IYBE 5IYCE 1TWCE 3I4NE 2E2JE 3CQZE 4A93E 3FKIE 4A3EE 4QIWH 1TWAE 2R93E 3M4OE 4Y7NE 3GTLE 3S1NE 4A3LE 4BXXE 2R92E 2NVYE 5M5XE 2Y0SH 4A3BE 4A3DE 4A3ME 3GTGE 4A3FE 4A3KE 1DZFA 3GTPE 4Y52E 3S1ME 3GTME 2NVTE 3HOZE 5M3FE 2WAQH 3PO2E 5FLME 2JA8E 2VUME 2E2IE 1EIKA 4BY7E 3HOWE 3GTQE 4A3GE 4X6AE 2JA6E 4BY1E 4C3IE 4BBRE 3H3VF 3HOYE 2JA5E 3S1RE 4AYBH 3S16E 3PO3E 2WB1H 5C44E 5C3EE 3HKZH 1I6HE 1TWHE 5C4XE 3HOVE 5IP9E 3S1QE 5C4JE 5M5WE 4BBSE 3S2HE 3RZOE 1WCME 2PMZH 2NVXE 4A3IE 2R7ZE 1K83E 1Y1WE 2NVQE 2JA7E 3GTOE 5FJ8E 5M5YE 4A3CE 5IYDE 2E2HE 3K7AE 4C3HE 1SFOE 3HOXE 3S14E 4A3JE 3S15E 3H0GE 5IP7E 1TWFE 3M3YE 1I3QE 1TWGE 1R9TE 3RZDE 3GTKE 3S2DE 2YU9E 4C3JE 3S17E 3I4ME
chains in the Genus database with same CATH superfamily
2B63E 2KRXA 4C2ME 3GTOF 5FJ8F 3GTJE 5M3ME 5M5YF 1YNNK 5IYCF 5D4DE 5IYDF 2E2HF 4A3CF 4XLNE 3K7AF 1I50E 3CQZF 1SFOF 3HOXF 3HOUE 1Y1VE 5D4CE 4A3JF 3S15F 1IW7E 2R93F 5IYBE 3H0GF 4KN7E 1TWFF 5IP7F 5E17E 3GTLF 1I3QF 5IYCE 1TWGF 1TWCE 3I4NE 2E2JE 3CQZE 4OIPE 4A93E 3RZDF 3GTKF 3FKIE 4A3EE 4OIRE 4QIWH 1TWAE 3S2DF 2R93E 1K83F 3S17F 3M4OE 3I4MF 4Y7NE 3GTLE 1QKLA 4KMUE 3S1NE 4A3BF 4A3LE 3GTJF 4BXXE 2R92E 4JK1E 5M3MF 4LJZE 4XLPE 4G7OE 1I6VE 3GTGF 4A3FF 1I50F 4OINE 2NVYE 1Y1VF 3HOUF 4LLGE 4Y52F 5M5XE 2Y0SH 4A3BE 5IYBF 4A3DE 2NVTF 4MQ9E 4A3ME 5M3FF 3GTGE 1TWCF 4MEYE 3I4NF 2E2JF 4A3FE 4A3KE 1DZFA 1YNJK 4A93F 3GTPE 3FKIF 4A3EF 4Y52E 3S1ME 1TWAF 3GTME 3WODE 2NVQF 3M4OF 2NVTE 4Y7NF 3HOZE 2O5IE 3PO2F 5FLMF 3S1NF 5M3FE 4A3LF 2Y0SI 2WAQH 4BXXF 2R92F 4G7HE 1SMYE 2E2IF 2VUMF 2NVYF 4BY7F 3HOWF 5M5XF 3PO2E 4YFXE 5FLME 4QIWK 4A3DF 2JA8E 4XSZE 2VUME 2E2IE 4A3MF 1EIKA 5D4EE 4A3KF 4BY7E 3HOWE 5BYHE 5E18E 3GTPF 1HQME 3GTQE 4A3GE 4X6AE 3GTMF 3S1MF 2PPBE 2JA6E 3EQLE 5TMCE 5C44F 3HOZF 1I6HF 1TWHF 4BY1E 4LK0E 4C3IE 4BBRE 3H3VF 3HOYE 4LK1E 5IP9F 2JA5E 5IPLE 2A68E 3S1RE 3S1QF 5C4JF 4AYBH 4KN4E 3S16E 3RZOF 3PO3E 2WB1H 5C44E 5C3EE 3HKZH 1I6HE 1TWHE 5C4XE 2A69E 3HOVE 2JA8F 5IP9E 4MEXE 3S1QE 5C4JE 2WAQK 5M5WE 4BBSE 2R7ZF 3S2HE 3RZOE 4ZH4E 3GTQF 4A3GF 4X6AF 1WCME 2A6HE 2PMZH 2JA6F 2NVXE 4Q4ZE 2WB1I 4BY1F 4A3IE 4BBRF 5TMFE 4C3IF 3HOYF 2PMZK 2R7ZE 2JA5F 1K83E 3S1RF 4XSXE 1Y1WE 3DXJE 2NVQE 4C3HF 3H3VG 3S16F 2JA7E 2CW0E 4YFNE 1ZYRE 3S14F 4G7ZE 5C3EF 3PO3F 2A6EE 5C4XF 3GTOE 5FJ8E 3HOVF 4YFKE 3M3YF 5M5YE 4A3CE 5IYDE 2E2HE 3K7AE 5M5WF 1R9TF 4C3HE 1SFOE 3HOXE 3S2HF 4BBSF 3S14E 4A3JE 3S15E 2YU9F 3H0GE 5IP7E 1TWFE 1WCMF 3M3YE 4Q5SE 4AYBK 4C3JF 4OIOE 2NVXF 2B63F 1I3QE 3HKZK 4C2MF 2BE5E 4GZYE 2O5JE 1TWGE 4A3IF 4OIQE 1R9TE 3RZDE 3GTKE 4YG2E 1Y1WF 3S2DE 2YU9E 4C3JE 3S17E 2JA7F 3I4ME
chains in the Genus database with same CATH topology
2B63E 4C2ME 3GTJE 5M3ME 1I50E 3HOUE 1Y1VE 5IYBE 5IYCE 1TWCE 3I4NE 2E2JE 3CQZE 4A93E 3FKIE 4A3EE 4QIWH 1TWAE 2R93E 3M4OE 4Y7NE 3GTLE 3S1NE 4A3LE 4BXXE 2R92E 2NVYE 5M5XE 2Y0SH 4A3BE 4A3DE 4A3ME 3GTGE 4A3FE 4A3KE 1DZFA 3GTPE 4Y52E 3S1ME 3GTME 2NVTE 3HOZE 5M3FE 2WAQH 3PO2E 5FLME 2JA8E 2VUME 2E2IE 1EIKA 4BY7E 3HOWE 3GTQE 4A3GE 4X6AE 2JA6E 4BY1E 4C3IE 4BBRE 3H3VF 3HOYE 2JA5E 3S1RE 4AYBH 3S16E 3PO3E 2WB1H 5C44E 5C3EE 3HKZH 1I6HE 1TWHE 5C4XE 3HOVE 5IP9E 3S1QE 5C4JE 5M5WE 4BBSE 3S2HE 3RZOE 1WCME 2PMZH 2NVXE 4A3IE 2R7ZE 1K83E 1Y1WE 2NVQE 2JA7E 3GTOE 5FJ8E 5M5YE 4A3CE 5IYDE 2E2HE 3K7AE 4C3HE 1SFOE 3HOXE 3S14E 4A3JE 3S15E 3H0GE 5IP7E 1TWFE 3M3YE 1I3QE 1TWGE 1R9TE 3RZDE 3GTKE 3S2DE 2YU9E 4C3JE 3S17E 3I4ME
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B63 E;  4C2M E;  3GTJ E;  5M3M E;  1I50 E;  3HOU E;  1Y1V E;  5IYB E;  5IYC E;  1TWC E;  3I4N E;  2E2J E;  3CQZ E;  4A93 E;  3FKI E;  4A3E E;  4QIW H;  1TWA E;  2R93 E;  3M4O E;  4Y7N E;  3GTL E;  3S1N E;  4A3L E;  4BXX E;  2R92 E;  2NVY E;  5M5X E;  2Y0S H;  4A3B E;  4A3D E;  4A3M E;  3GTG E;  4A3F E;  4A3K E;  1DZF A;  3GTP E;  4Y52 E;  3S1M E;  3GTM E;  2NVT E;  3HOZ E;  5M3F E;  2WAQ H;  3PO2 E;  5FLM E;  2JA8 E;  2VUM E;  2E2I E;  1EIK A;  4BY7 E;  3HOW E;  3GTQ E;  4A3G E;  4X6A E;  2JA6 E;  4BY1 E;  4C3I E;  4BBR E;  3H3V F;  3HOY E;  2JA5 E;  3S1R E;  4AYB H;  3S16 E;  3PO3 E;  2WB1 H;  5C44 E;  5C3E E;  3HKZ H;  1I6H E;  1TWH E;  5C4X E;  3HOV E;  5IP9 E;  3S1Q E;  5C4J E;  5M5W E;  4BBS E;  3S2H E;  3RZO E;  1WCM E;  2PMZ H;  2NVX E;  4A3I E;  2R7Z E;  1K83 E;  1Y1W E;  2NVQ E;  2JA7 E;  3GTO E;  5FJ8 E;  5M5Y E;  4A3C E;  5IYD E;  2E2H E;  3K7A E;  4C3H E;  1SFO E;  3HOX E;  3S14 E;  4A3J E;  3S15 E;  3H0G E;  5IP7 E;  1TWF E;  3M3Y E;  1I3Q E;  1TWG E;  1R9T E;  3RZD E;  3GTK E;  3S2D E;  2YU9 E;  4C3J E;  3S17 E;  3I4M E; 
#chains in the Genus database with same CATH topology
 2B63 E;  2KRX A;  4C2M E;  3GTO F;  5FJ8 F;  3GTJ E;  5M3M E;  5M5Y F;  1YNN K;  5IYC F;  5D4D E;  5IYD F;  2E2H F;  4A3C F;  4XLN E;  3K7A F;  1I50 E;  3CQZ F;  1SFO F;  3HOX F;  3HOU E;  1Y1V E;  5D4C E;  4A3J F;  3S15 F;  1IW7 E;  2R93 F;  5IYB E;  3H0G F;  4KN7 E;  1TWF F;  5IP7 F;  5E17 E;  3GTL F;  1I3Q F;  5IYC E;  1TWG F;  1TWC E;  3I4N E;  2E2J E;  3CQZ E;  4OIP E;  4A93 E;  3RZD F;  3GTK F;  3FKI E;  4A3E E;  4OIR E;  4QIW H;  1TWA E;  3S2D F;  2R93 E;  1K83 F;  3S17 F;  3M4O E;  3I4M F;  4Y7N E;  3GTL E;  1QKL A;  4KMU E;  3S1N E;  4A3B F;  4A3L E;  3GTJ F;  4BXX E;  2R92 E;  4JK1 E;  5M3M F;  4LJZ E;  4XLP E;  4G7O E;  1I6V E;  3GTG F;  4A3F F;  1I50 F;  4OIN E;  2NVY E;  1Y1V F;  3HOU F;  4LLG E;  4Y52 F;  5M5X E;  2Y0S H;  4A3B E;  5IYB F;  4A3D E;  2NVT F;  4MQ9 E;  4A3M E;  5M3F F;  3GTG E;  1TWC F;  4MEY E;  3I4N F;  2E2J F;  4A3F E;  4A3K E;  1DZF A;  1YNJ K;  4A93 F;  3GTP E;  3FKI F;  4A3E F;  4Y52 E;  3S1M E;  1TWA F;  3GTM E;  3WOD E;  2NVQ F;  3M4O F;  2NVT E;  4Y7N F;  3HOZ E;  2O5I E;  3PO2 F;  5FLM F;  3S1N F;  5M3F E;  4A3L F;  2Y0S I;  2WAQ H;  4BXX F;  2R92 F;  4G7H E;  1SMY E;  2E2I F;  2VUM F;  2NVY F;  4BY7 F;  3HOW F;  5M5X F;  3PO2 E;  4YFX E;  5FLM E;  4QIW K;  4A3D F;  2JA8 E;  4XSZ E;  2VUM E;  2E2I E;  4A3M F;  1EIK A;  5D4E E;  4A3K F;  4BY7 E;  3HOW E;  5BYH E;  5E18 E;  3GTP F;  1HQM E;  3GTQ E;  4A3G E;  4X6A E;  3GTM F;  3S1M F;  2PPB E;  2JA6 E;  3EQL E;  5TMC E;  5C44 F;  3HOZ F;  1I6H F;  1TWH F;  4BY1 E;  4LK0 E;  4C3I E;  4BBR E;  3H3V F;  3HOY E;  4LK1 E;  5IP9 F;  2JA5 E;  5IPL E;  2A68 E;  3S1R E;  3S1Q F;  5C4J F;  4AYB H;  4KN4 E;  3S16 E;  3RZO F;  3PO3 E;  2WB1 H;  5C44 E;  5C3E E;  3HKZ H;  1I6H E;  1TWH E;  5C4X E;  2A69 E;  3HOV E;  2JA8 F;  5IP9 E;  4MEX E;  3S1Q E;  5C4J E;  2WAQ K;  5M5W E;  4BBS E;  2R7Z F;  3S2H E;  3RZO E;  4ZH4 E;  3GTQ F;  4A3G F;  4X6A F;  1WCM E;  2A6H E;  2PMZ H;  2JA6 F;  2NVX E;  4Q4Z E;  2WB1 I;  4BY1 F;  4A3I E;  4BBR F;  5TMF E;  4C3I F;  3HOY F;  2PMZ K;  2R7Z E;  2JA5 F;  1K83 E;  3S1R F;  4XSX E;  1Y1W E;  3DXJ E;  2NVQ E;  4C3H F;  3H3V G;  3S16 F;  2JA7 E;  2CW0 E;  4YFN E;  1ZYR E;  3S14 F;  4G7Z E;  5C3E F;  3PO3 F;  2A6E E;  5C4X F;  3GTO E;  5FJ8 E;  3HOV F;  4YFK E;  3M3Y F;  5M5Y E;  4A3C E;  5IYD E;  2E2H E;  3K7A E;  5M5W F;  1R9T F;  4C3H E;  1SFO E;  3HOX E;  3S2H F;  4BBS F;  3S14 E;  4A3J E;  3S15 E;  2YU9 F;  3H0G E;  5IP7 E;  1TWF E;  1WCM F;  3M3Y E;  4Q5S E;  4AYB K;  4C3J F;  4OIO E;  2NVX F;  2B63 F;  1I3Q E;  3HKZ K;  4C2M F;  2BE5 E;  4GZY E;  2O5J E;  1TWG E;  4A3I F;  4OIQ E;  1R9T E;  3RZD E;  3GTK E;  4YG2 E;  1Y1W F;  3S2D E;  2YU9 E;  4C3J E;  3S17 E;  2JA7 F;  3I4M E; 
#chains in the Genus database with same CATH homology
 2B63 E;  4C2M E;  3GTJ E;  5M3M E;  1I50 E;  3HOU E;  1Y1V E;  5IYB E;  5IYC E;  1TWC E;  3I4N E;  2E2J E;  3CQZ E;  4A93 E;  3FKI E;  4A3E E;  4QIW H;  1TWA E;  2R93 E;  3M4O E;  4Y7N E;  3GTL E;  3S1N E;  4A3L E;  4BXX E;  2R92 E;  2NVY E;  5M5X E;  2Y0S H;  4A3B E;  4A3D E;  4A3M E;  3GTG E;  4A3F E;  4A3K E;  1DZF A;  3GTP E;  4Y52 E;  3S1M E;  3GTM E;  2NVT E;  3HOZ E;  5M3F E;  2WAQ H;  3PO2 E;  5FLM E;  2JA8 E;  2VUM E;  2E2I E;  1EIK A;  4BY7 E;  3HOW E;  3GTQ E;  4A3G E;  4X6A E;  2JA6 E;  4BY1 E;  4C3I E;  4BBR E;  3H3V F;  3HOY E;  2JA5 E;  3S1R E;  4AYB H;  3S16 E;  3PO3 E;  2WB1 H;  5C44 E;  5C3E E;  3HKZ H;  1I6H E;  1TWH E;  5C4X E;  3HOV E;  5IP9 E;  3S1Q E;  5C4J E;  5M5W E;  4BBS E;  3S2H E;  3RZO E;  1WCM E;  2PMZ H;  2NVX E;  4A3I E;  2R7Z E;  1K83 E;  1Y1W E;  2NVQ E;  2JA7 E;  3GTO E;  5FJ8 E;  5M5Y E;  4A3C E;  5IYD E;  2E2H E;  3K7A E;  4C3H E;  1SFO E;  3HOX E;  3S14 E;  4A3J E;  3S15 E;  3H0G E;  5IP7 E;  1TWF E;  3M3Y E;  1I3Q E;  1TWG E;  1R9T E;  3RZD E;  3GTK E;  3S2D E;  2YU9 E;  4C3J E;  3S17 E;  3I4M E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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