3HOUF

Complete rna polymerase ii elongation complex i with a t-u mismatch
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
87
structure length
87
Chain Sequence
LKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 26
structure length 87
sequence length 87
chains with identical sequence R
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 3houF00
2A6EE 2WB1I 1I6HF 2NVXF 5D4CE 3GTQF 1YNNK 2R93F 2NVYF 2JA5F 2JA8F 4JK1E 5C4XF 1I6VE 4AYBK 5M5XF 5IYCF 5FJ8F 2CW0E 5FLMF 2PMZK 3GTJF 4G7HE 4C2MF 3CQZF 3H0GF 4G7OE 1TWGF 3GTGF 3DXJE 3S1RF 4KN4E 5C4JF 3GTPF 5C3EF 3HOZF 5TMFE 4Y52F 5D4DE 2B63F 4BY1F 4A3JF 2JA7F 5M3MF 3HKZK 3S1NF 3WODE 4KN7E 3S14F 4BXXF 4MEYE 4OIRE 3I4NF 4C3HF 5M3FF 2YU9F 2Y0SI 5C44F 3M3YF 3S1MF 4G7ZE 3RZOF 3S1QF 4GZYE 4YFNE 3RZDF 4C3IF 4A3IF 2JA6F 4A3EF 1I50F 2A69E 5D4EE 5IP7F 4XLNE 4A3BF 1Y1VF 4YG2E 1SFOF 3HOYF 2WAQK 4OIQE 4OIOE 4LJZE 3HOXF 3HOVF 1QKLA 4BBRF 4A93F 4A3LF 4A3MF 1YNJK 3GTMF 2E2IF 2A68E 1TWFF 2VUMF 3GTLF 4OINE 4YFXE 2E2JF 4A3GF 3PO2F 1I3QF 1ZYRE 3K7AF 5IYDF 3I4MF 4YFKE 3S15F 4LK1E 5BYHE 4X6AF 1HQME 3GTOF 2E2HF 3HOWF 3PO3F 4A3DF 1Y1WF 3HOUF 2BE5E 4MQ9E 4A3CF 3S2HF 1TWCF 1IW7E 1TWHF 5M5WF 4A3KF 3H3VG 4BBSF 1K83F 4XLPE 1R9TF 4KMUE 2O5JE 2NVTF 5IYBF 1SMYE 4C3JF 4XSXE 4Y7NF 5IPLE 4XSZE 4LLGE 3M4OF 2PPBE 5E17E 4OIPE 4MEXE 4A3FF 3EQLE 2A6HE 1TWAF 5TMCE 3FKIF 4Q5SE 2R7ZF 4ZH4E 2R92F 3GTKF 3S17F 4BY7F 2O5IE 3S16F 4Q4ZE 5IP9F 3S2DF 1WCMF 2NVQF 5E18E 4LK0E 5M5YF
chains in the Genus database with same CATH superfamily
4A3ME 2B63E 2A6EE 2WB1I 1I6HF 4BY1E 4A3JE 2E2IE 2NVXF 5D4CE 3GTQF 1YNNK 3S1NE 2R93F 1TWFE 2NVYF 2JA5F 2JA8F 2VUME 4JK1E 3GTLE 2E2JE 4A3GE 3PO2E 4C3HE 5C4XF 1I6VE 5IYDE 4AYBK 5M5XF 5IYCF 5FJ8F 3I4ME 2CW0E 5FLMF 3S15E 3RZOE 2PMZK 3GTJF 4X6AE 4G7HE 4C2MF 3RZDE 4A3IE 3GTOE 1EIKA 2JA6E 3HOWE 3CQZF 3H0GF 3PO3E 1I50E 4A3DE 4G7OE 1TWGF 3GTGF 3DXJE 3S1RF 1Y1WE 4KN4E 5C4JF 3GTPF 5C3EF 2KRXA 1SFOE 3HOZF 5TMFE 4Y52F 5D4DE 4QIWH 2B63F 4A3CE 4BY1F 4A3JF 2JA7F 5M3MF 1TWCE 3HKZK 3S1NF 1DZFA 3WODE 1TWHE 4KN7E 3S14F 4BXXF 5M5WE 3GTME 4MEYE 4A3KE 3S17F 4OIRE 3I4NF 4C3HF 1K83E 5M3FF 2YU9F 2Y0SI 5C44F 3M3YF 3S1MF 5IYBE 1I3QE 3K7AE 4G7ZE 3RZOF 3S1QF 3M4OE 4GZYE 4YFNE 3RZDF 4C3IF 4A3IF 2JA6F 4A3FE 4A3EF 1I50F 2A69E 5D4EE 2E2HE 1TWAE 5IP7F 4XLNE 4A3BF 4YG2E 1Y1VF 1SFOF 3HOYF 3FKIE 2WAQK 2R7ZE 4OIQE 3GTKE 3S2DE 4OIOE 4BY7E 4LJZE 3HOUE 5IP9E 3HOXF 1QKLA 3HOVF 2NVQE 4BBRF 4A93F 4A3LF 4A3MF 5M5YE 1YNJK 3S2HE 1I6HE 3GTMF 2E2IF 2NVXE 2A68E 3GTQE 1TWFF 2R93E 2VUMF 2WB1H 3GTLF 2NVYE 4OINE 4A3LE 4YFXE 2E2JF 4BBSE 4A3GF 3PO2F 3S2DF 1R9TE 5C4XE 1I3QF 1ZYRE 3K7AF 5IYDF 4QIWK 2NVTE 5M5XE 4C3JE 5IYCE 4YFKE 4Y7NE 3I4MF 4LK1E 3S15F 5BYHE 5FLME 3H3VF 4X6AF 3GTJE 1HQME 4C2ME 2E2HF 3GTOF 3HOWF 3PO3F 4A3DF 3H0GE 1TWGE 1Y1WF 3GTGE 3S1RE 3HOUF 5C4JE 3HOZE 5C3EE 2BE5E 4MQ9E 3S17E 2R92E 3S16E 4A3CF 4Y52E 4AYBH 1WCME 3S2HF 1TWCF 2JA7E 5M3ME 1IW7E 1TWHF 2PMZH 5M5WF 3S14E 4BXXE 4A3KF 3H3VG 4BBSF 3I4NE 1K83F 4XLPE 1R9TF 5M3FE 4KMUE 2WAQH 2JA5E 2JA8E 2YU9E 2O5JE 2NVTF 5C44E 5IYBF 1SMYE 4C3JF 3M3YE 4XSXE 4Y7NF 3S1ME 5IPLE 4XSZE 2Y0SH 4LLGE 3M4OF 3S1QE 2PPBE 5E17E 4OIPE 5FJ8E 4C3IE 4MEXE 4A3FF 3EQLE 3HKZH 2A6HE 4A3EE 1TWAF 5IP7E 5TMCE 4A3BE 3CQZE 1Y1VE 3FKIF 4Q5SE 4ZH4E 2R92F 3GTKF 3HOYE 4BY7F 2O5IE 2R7ZF 4Q4ZE 5IP9F 3GTPE 3S16F 3HOXE 1WCMF 2NVQF 3HOVE 5E18E 4BBRE 4A93E 4LK0E 5M5YF
chains in the Genus database with same CATH topology
2A6EE 2WB1I 1I6HF 2NVXF 5D4CE 3GTQF 1YNNK 2R93F 2NVYF 2JA5F 2JA8F 4JK1E 5C4XF 1I6VE 4AYBK 5M5XF 5IYCF 5FJ8F 2CW0E 5FLMF 2PMZK 3GTJF 4G7HE 4C2MF 3CQZF 3H0GF 4G7OE 1TWGF 3GTGF 3DXJE 3S1RF 4KN4E 5C4JF 3GTPF 5C3EF 2KRXA 3HOZF 5TMFE 4Y52F 5D4DE 2B63F 4BY1F 4A3JF 2JA7F 5M3MF 3HKZK 3S1NF 3WODE 4KN7E 3S14F 4BXXF 4MEYE 4OIRE 3I4NF 4C3HF 5M3FF 2YU9F 2Y0SI 5C44F 3M3YF 3S1MF 4G7ZE 3RZOF 3S1QF 4GZYE 4YFNE 3RZDF 4C3IF 4A3IF 2JA6F 4A3EF 1I50F 2A69E 5D4EE 5IP7F 4XLNE 4A3BF 1Y1VF 4YG2E 1SFOF 3HOYF 2WAQK 4OIQE 4OIOE 4LJZE 3HOXF 3HOVF 1QKLA 4BBRF 4A93F 4A3LF 4A3MF 1YNJK 3GTMF 2E2IF 2A68E 1TWFF 2VUMF 3GTLF 4OINE 4YFXE 2E2JF 4A3GF 3PO2F 1I3QF 1ZYRE 3K7AF 5IYDF 4QIWK 3I4MF 4YFKE 3S15F 4LK1E 5BYHE 4X6AF 1HQME 3GTOF 2E2HF 3HOWF 3PO3F 4A3DF 1Y1WF 3HOUF 2BE5E 4MQ9E 4A3CF 3S2HF 1TWCF 1IW7E 1TWHF 5M5WF 4A3KF 3H3VG 4BBSF 1K83F 4XLPE 1R9TF 4KMUE 2O5JE 2NVTF 5IYBF 1SMYE 4C3JF 4XSXE 4Y7NF 5IPLE 4XSZE 4LLGE 3M4OF 2PPBE 5E17E 4OIPE 4MEXE 4A3FF 3EQLE 2A6HE 1TWAF 5TMCE 3FKIF 4Q5SE 2R7ZF 4ZH4E 2R92F 3GTKF 3S17F 4BY7F 2O5IE 3S16F 4Q4ZE 5IP9F 3S2DF 1WCMF 2NVQF 5E18E 4LK0E 5M5YF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A6E E;  2WB1 I;  1I6H F;  2NVX F;  5D4C E;  3GTQ F;  1YNN K;  2R93 F;  2NVY F;  2JA5 F;  2JA8 F;  4JK1 E;  5C4X F;  1I6V E;  4AYB K;  5M5X F;  5IYC F;  5FJ8 F;  2CW0 E;  5FLM F;  2PMZ K;  3GTJ F;  4G7H E;  4C2M F;  3CQZ F;  3H0G F;  4G7O E;  1TWG F;  3GTG F;  3DXJ E;  3S1R F;  4KN4 E;  5C4J F;  3GTP F;  5C3E F;  3HOZ F;  5TMF E;  4Y52 F;  5D4D E;  2B63 F;  4BY1 F;  4A3J F;  2JA7 F;  5M3M F;  3HKZ K;  3S1N F;  3WOD E;  4KN7 E;  3S14 F;  4BXX F;  4MEY E;  4OIR E;  3I4N F;  4C3H F;  5M3F F;  2YU9 F;  2Y0S I;  5C44 F;  3M3Y F;  3S1M F;  4G7Z E;  3RZO F;  3S1Q F;  4GZY E;  4YFN E;  3RZD F;  4C3I F;  4A3I F;  2JA6 F;  4A3E F;  1I50 F;  2A69 E;  5D4E E;  5IP7 F;  4XLN E;  4A3B F;  1Y1V F;  4YG2 E;  1SFO F;  3HOY F;  2WAQ K;  4OIQ E;  4OIO E;  4LJZ E;  3HOX F;  3HOV F;  1QKL A;  4BBR F;  4A93 F;  4A3L F;  4A3M F;  1YNJ K;  3GTM F;  2E2I F;  2A68 E;  1TWF F;  2VUM F;  3GTL F;  4OIN E;  4YFX E;  2E2J F;  4A3G F;  3PO2 F;  1I3Q F;  1ZYR E;  3K7A F;  5IYD F;  3I4M F;  4YFK E;  3S15 F;  4LK1 E;  5BYH E;  4X6A F;  1HQM E;  3GTO F;  2E2H F;  3HOW F;  3PO3 F;  4A3D F;  1Y1W F;  3HOU F;  2BE5 E;  4MQ9 E;  4A3C F;  3S2H F;  1TWC F;  1IW7 E;  1TWH F;  5M5W F;  4A3K F;  3H3V G;  4BBS F;  1K83 F;  4XLP E;  1R9T F;  4KMU E;  2O5J E;  2NVT F;  5IYB F;  1SMY E;  4C3J F;  4XSX E;  4Y7N F;  5IPL E;  4XSZ E;  4LLG E;  3M4O F;  2PPB E;  5E17 E;  4OIP E;  4MEX E;  4A3F F;  3EQL E;  2A6H E;  1TWA F;  5TMC E;  3FKI F;  4Q5S E;  2R7Z F;  4ZH4 E;  2R92 F;  3GTK F;  3S17 F;  4BY7 F;  2O5I E;  3S16 F;  4Q4Z E;  5IP9 F;  3S2D F;  1WCM F;  2NVQ F;  5E18 E;  4LK0 E;  5M5Y F; 
#chains in the Genus database with same CATH topology
 4A3M E;  2B63 E;  2A6E E;  2WB1 I;  1I6H F;  4BY1 E;  4A3J E;  2E2I E;  2NVX F;  5D4C E;  3GTQ F;  1YNN K;  3S1N E;  2R93 F;  1TWF E;  2NVY F;  2JA5 F;  2JA8 F;  2VUM E;  4JK1 E;  3GTL E;  2E2J E;  4A3G E;  3PO2 E;  4C3H E;  5C4X F;  1I6V E;  5IYD E;  4AYB K;  5M5X F;  5IYC F;  5FJ8 F;  3I4M E;  2CW0 E;  5FLM F;  3S15 E;  3RZO E;  2PMZ K;  3GTJ F;  4X6A E;  4G7H E;  4C2M F;  3RZD E;  4A3I E;  3GTO E;  1EIK A;  2JA6 E;  3HOW E;  3CQZ F;  3H0G F;  3PO3 E;  1I50 E;  4A3D E;  4G7O E;  1TWG F;  3GTG F;  3DXJ E;  3S1R F;  1Y1W E;  4KN4 E;  5C4J F;  3GTP F;  5C3E F;  2KRX A;  1SFO E;  3HOZ F;  5TMF E;  4Y52 F;  5D4D E;  4QIW H;  2B63 F;  4A3C E;  4BY1 F;  4A3J F;  2JA7 F;  5M3M F;  1TWC E;  3HKZ K;  3S1N F;  1DZF A;  3WOD E;  1TWH E;  4KN7 E;  3S14 F;  4BXX F;  5M5W E;  3GTM E;  4MEY E;  4A3K E;  3S17 F;  4OIR E;  3I4N F;  4C3H F;  1K83 E;  5M3F F;  2YU9 F;  2Y0S I;  5C44 F;  3M3Y F;  3S1M F;  5IYB E;  1I3Q E;  3K7A E;  4G7Z E;  3RZO F;  3S1Q F;  3M4O E;  4GZY E;  4YFN E;  3RZD F;  4C3I F;  4A3I F;  2JA6 F;  4A3F E;  4A3E F;  1I50 F;  2A69 E;  5D4E E;  2E2H E;  1TWA E;  5IP7 F;  4XLN E;  4A3B F;  4YG2 E;  1Y1V F;  1SFO F;  3HOY F;  3FKI E;  2WAQ K;  2R7Z E;  4OIQ E;  3GTK E;  3S2D E;  4OIO E;  4BY7 E;  4LJZ E;  3HOU E;  5IP9 E;  3HOX F;  1QKL A;  3HOV F;  2NVQ E;  4BBR F;  4A93 F;  4A3L F;  4A3M F;  5M5Y E;  1YNJ K;  3S2H E;  1I6H E;  3GTM F;  2E2I F;  2NVX E;  2A68 E;  3GTQ E;  1TWF F;  2R93 E;  2VUM F;  2WB1 H;  3GTL F;  2NVY E;  4OIN E;  4A3L E;  4YFX E;  2E2J F;  4BBS E;  4A3G F;  3PO2 F;  3S2D F;  1R9T E;  5C4X E;  1I3Q F;  1ZYR E;  3K7A F;  5IYD F;  4QIW K;  2NVT E;  5M5X E;  4C3J E;  5IYC E;  4YFK E;  4Y7N E;  3I4M F;  4LK1 E;  3S15 F;  5BYH E;  5FLM E;  3H3V F;  4X6A F;  3GTJ E;  1HQM E;  4C2M E;  2E2H F;  3GTO F;  3HOW F;  3PO3 F;  4A3D F;  3H0G E;  1TWG E;  1Y1W F;  3GTG E;  3S1R E;  3HOU F;  5C4J E;  3HOZ E;  5C3E E;  2BE5 E;  4MQ9 E;  3S17 E;  2R92 E;  3S16 E;  4A3C F;  4Y52 E;  4AYB H;  1WCM E;  3S2H F;  1TWC F;  2JA7 E;  5M3M E;  1IW7 E;  1TWH F;  2PMZ H;  5M5W F;  3S14 E;  4BXX E;  4A3K F;  3H3V G;  4BBS F;  3I4N E;  1K83 F;  4XLP E;  1R9T F;  5M3F E;  4KMU E;  2WAQ H;  2JA5 E;  2JA8 E;  2YU9 E;  2O5J E;  2NVT F;  5C44 E;  5IYB F;  1SMY E;  4C3J F;  3M3Y E;  4XSX E;  4Y7N F;  3S1M E;  5IPL E;  4XSZ E;  2Y0S H;  4LLG E;  3M4O F;  3S1Q E;  2PPB E;  5E17 E;  4OIP E;  5FJ8 E;  4C3I E;  4MEX E;  4A3F F;  3EQL E;  3HKZ H;  2A6H E;  4A3E E;  1TWA F;  5IP7 E;  5TMC E;  4A3B E;  3CQZ E;  1Y1V E;  3FKI F;  4Q5S E;  4ZH4 E;  2R92 F;  3GTK F;  3HOY E;  4BY7 F;  2O5I E;  2R7Z F;  4Q4Z E;  5IP9 F;  3GTP E;  3S16 F;  3HOX E;  1WCM F;  2NVQ F;  3HOV E;  5E18 E;  4BBR E;  4A93 E;  4LK0 E;  5M5Y F; 
#chains in the Genus database with same CATH homology
 2A6E E;  2WB1 I;  1I6H F;  2NVX F;  5D4C E;  3GTQ F;  1YNN K;  2R93 F;  2NVY F;  2JA5 F;  2JA8 F;  4JK1 E;  5C4X F;  1I6V E;  4AYB K;  5M5X F;  5IYC F;  5FJ8 F;  2CW0 E;  5FLM F;  2PMZ K;  3GTJ F;  4G7H E;  4C2M F;  3CQZ F;  3H0G F;  4G7O E;  1TWG F;  3GTG F;  3DXJ E;  3S1R F;  4KN4 E;  5C4J F;  3GTP F;  5C3E F;  2KRX A;  3HOZ F;  5TMF E;  4Y52 F;  5D4D E;  2B63 F;  4BY1 F;  4A3J F;  2JA7 F;  5M3M F;  3HKZ K;  3S1N F;  3WOD E;  4KN7 E;  3S14 F;  4BXX F;  4MEY E;  4OIR E;  3I4N F;  4C3H F;  5M3F F;  2YU9 F;  2Y0S I;  5C44 F;  3M3Y F;  3S1M F;  4G7Z E;  3RZO F;  3S1Q F;  4GZY E;  4YFN E;  3RZD F;  4C3I F;  4A3I F;  2JA6 F;  4A3E F;  1I50 F;  2A69 E;  5D4E E;  5IP7 F;  4XLN E;  4A3B F;  1Y1V F;  4YG2 E;  1SFO F;  3HOY F;  2WAQ K;  4OIQ E;  4OIO E;  4LJZ E;  3HOX F;  3HOV F;  1QKL A;  4BBR F;  4A93 F;  4A3L F;  4A3M F;  1YNJ K;  3GTM F;  2E2I F;  2A68 E;  1TWF F;  2VUM F;  3GTL F;  4OIN E;  4YFX E;  2E2J F;  4A3G F;  3PO2 F;  1I3Q F;  1ZYR E;  3K7A F;  5IYD F;  4QIW K;  3I4M F;  4YFK E;  3S15 F;  4LK1 E;  5BYH E;  4X6A F;  1HQM E;  3GTO F;  2E2H F;  3HOW F;  3PO3 F;  4A3D F;  1Y1W F;  3HOU F;  2BE5 E;  4MQ9 E;  4A3C F;  3S2H F;  1TWC F;  1IW7 E;  1TWH F;  5M5W F;  4A3K F;  3H3V G;  4BBS F;  1K83 F;  4XLP E;  1R9T F;  4KMU E;  2O5J E;  2NVT F;  5IYB F;  1SMY E;  4C3J F;  4XSX E;  4Y7N F;  5IPL E;  4XSZ E;  4LLG E;  3M4O F;  2PPB E;  5E17 E;  4OIP E;  4MEX E;  4A3F F;  3EQL E;  2A6H E;  1TWA F;  5TMC E;  3FKI F;  4Q5S E;  2R7Z F;  4ZH4 E;  2R92 F;  3GTK F;  3S17 F;  4BY7 F;  2O5I E;  3S16 F;  4Q4Z E;  5IP9 F;  3S2D F;  1WCM F;  2NVQ F;  5E18 E;  4LK0 E;  5M5Y F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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