3HOZE

Complete rna polymerase ii elongation complex iv with a t-u mismatch and a frayed rna 3'-guanine
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 56
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3hozE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3hozE02
4A3BE 3M3YE 4BY7E 3HOZE 3K7AE 1I50E 4A3IE 5M3FE 2JA7E 3S17E 2PMZH 5FJ8E 5C4JE 3GTLE 3I4NE 2NVYE 4C3JE 1Y1WE 4A3DE 3GTQE 4Y52E 4A3EE 2NVQE 1TWHE 2R7ZE 4C3IE 1TWGE 4Y7NE 3I4ME 3H0GE 4BXXE 2Y0SH 4BY1E 2NVTE 3S16E 1Y1VE 5M5YE 4BBRE 3GTJE 3S1RE 1EIKA 3PO3E 3GTGE 2VUME 2JA6E 4QIWH 1TWAE 2JA8E 4X6AE 3FKIE 1DZFA 5IP9E 5M5WE 4A3ME 2YU9E 4C3HE 1K83E 3S14E 5C44E 4BBSE 5IYBE 1SFOE 5FLME 3S2DE 4A3FE 3H3VF 1TWCE 5C3EE 2B63E 5IYCE 2WB1H 4A3JE 2R93E 3CQZE 3HKZH 5M3ME 3S2HE 3GTOE 3HOXE 4AYBH 3RZDE 3RZOE 2JA5E 3GTKE 3HOYE 3S1NE 3HOVE 5C4XE 1TWFE 3GTME 3PO2E 5IYDE 3M4OE 3GTPE 2E2IE 1R9TE 1I6HE 3S15E 1WCME 2E2HE 3S1QE 5M5XE 3S1ME 3HOUE 4A93E 1I3QE 4A3KE 4C2ME 2E2JE 3HOWE 5IP7E 2NVXE 2WAQH 4A3GE 2R92E 4A3LE 4A3CE
chains in the Genus database with same CATH superfamily
4MEYE 4A3BE 3M3YE 4BY7E 2WAQK 3RZDF 3RZOF 3HOZE 3S14F 4MQ9E 5C44F 3K7AE 3HOVF 1I50E 3S1NF 5C4XF 4A3IE 3GTMF 5M3FE 2JA7E 3PO2F 5IYDF 3M4OF 4Q5SE 2E2IF 1R9TF 4G7ZE 1I6HF 3GTPF 4JK1E 4OIRE 3S15F 3S17E 2PMZH 1QKLA 5FJ8E 5C4JE 1WCMF 3GTLE 2E2HF 3I4NE 2NVYE 3WODE 1YNNK 2B63F 4KMUE 3S1MF 3S1QF 4YFNE 4A93F 1I3QF 4C3JE 2R93F 3CQZF 4A3KF 1Y1WE 4C2MF 2PMZK 4A3DE 5IP7F 5M3MF 2NVXF 2PPBE 3GTQE 4Y52E 4A3GF 2A6EE 4A3EE 2R92F 4XLPE 2NVQE 1TWHE 2R7ZE 3S2HF 4A3CF 4C3IE 3HOXF 1TWGE 4Y7NE 3I4ME 4Q4ZE 4BY7F 2A68E 3H0GE 4BXXE 2Y0SH 2A69E 3K7AF 2JA5F 1I50F 4BY1E 2O5IE 2NVTE 4A3IF 3S16E 1Y1VE 5M5YE 4BBRE 3GTJE 3GTKF 3HOYF 1TWFF 3S1RE 4OIOE 5E17E 1EIKA 3PO3E 3S17F 4YFKE 3GTGE 2VUME 2JA6E 3GTLF 2NVYF 4QIWH 1TWAE 1YNJK 2BE5E 5M5XF 2JA8E 3HOUF 4X6AE 3FKIE 1Y1WF 3GTQF 2E2JF 1DZFA 4Y52F 3HOWF 4A3EF 5IP9E 5M5WE 4QIWK 4A3ME 2Y0SI 2YU9E 4C3HE 3DXJE 4XSZE 4C3IF 4A3LF 4Y7NF 4G7OE 4G7HE 4GZYE 4A3BF 1K83E 3S14E 3M3YF 4BXXF 5E18E 5C44E 5IPLE 3HOZF 1SMYE 2O5JE 4BBSE 2KRXA 4LLGE 5IYBE 1Y1VF 5M5YF 3GTJF 1SFOE 1ZYRE 5FLME 4MEXE 3S16F 3S1RF 5M3FF 3S2DE 2JA7F 5D4CE 4A3FE 3H3VF 2CW0E 1TWCE 5C3EE 2VUMF 2B63E 5IYCE 5FJ8F 5C4JF 2WB1H 4KN7E 3I4NF 4OIQE 4A3JE 5BYHE 2JA8F 2R93E 4OINE 3CQZE 4X6AF 3HKZH 3EQLE 5M3ME 4C3JF 4YFXE 5D4DE 4LJZE 1I6VE 4A3DF 5IP9F 4A3MF 4ZH4E 3S2HE 4C3HF 3GTOE 1IW7E 1TWHF 3HOXE 3HKZK 4AYBH 2A6HE 2NVQF 2R7ZF 5TMCE 1TWGF 1K83F 3I4MF 3RZDE 3RZOE 3H0GF 2JA5E 4BBSF 3GTKE 3HOYE 4KN4E 5IYBF 3S1NE 3HOVE 4AYBK 5C4XE 4BY1F 1TWFE 3GTME 5FLMF 1SFOF 2NVTF 3PO2E 2WB1I 4BBRF 5IYDE 3S2DF 1HQME 4OIPE 3M4OE 3GTPE 2E2IE 1R9TE 1I6HE 4A3FF 3S15E 1TWCF 5C3EF 2YU9F 4LK1E 3PO3F 5D4EE 1WCME 5IYCF 3GTGF 2E2HE 4XSXE 2JA6F 3S1QE 4A3JF 5M5XE 3S1ME 4YG2E 5TMFE 4XLNE 1TWAF 3HOUE 4A93E 1I3QE 3H3VG 4A3KE 4C2ME 2E2JE 3FKIF 3HOWE 5IP7E 2NVXE 2WAQH 4A3GE 2R92E 5M5WF 4LK0E 3GTOF 4A3LE 4A3CE
chains in the Genus database with same CATH topology
4A3BE 3M3YE 4BY7E 3HOZE 3K7AE 1I50E 4A3IE 5M3FE 2JA7E 3S17E 2PMZH 5FJ8E 5C4JE 3GTLE 3I4NE 2NVYE 4C3JE 1Y1WE 4A3DE 3GTQE 4Y52E 4A3EE 2NVQE 1TWHE 2R7ZE 4C3IE 1TWGE 4Y7NE 3I4ME 3H0GE 4BXXE 2Y0SH 4BY1E 2NVTE 3S16E 1Y1VE 5M5YE 4BBRE 3GTJE 3S1RE 1EIKA 3PO3E 3GTGE 2VUME 2JA6E 4QIWH 1TWAE 2JA8E 4X6AE 3FKIE 1DZFA 5IP9E 5M5WE 4A3ME 2YU9E 4C3HE 1K83E 3S14E 5C44E 4BBSE 5IYBE 1SFOE 5FLME 3S2DE 4A3FE 3H3VF 1TWCE 5C3EE 2B63E 5IYCE 2WB1H 4A3JE 2R93E 3CQZE 3HKZH 5M3ME 3S2HE 3GTOE 3HOXE 4AYBH 3RZDE 3RZOE 2JA5E 3GTKE 3HOYE 3S1NE 3HOVE 5C4XE 1TWFE 3GTME 3PO2E 5IYDE 3M4OE 3GTPE 2E2IE 1R9TE 1I6HE 3S15E 1WCME 2E2HE 3S1QE 5M5XE 3S1ME 3HOUE 4A93E 1I3QE 4A3KE 4C2ME 2E2JE 3HOWE 5IP7E 2NVXE 2WAQH 4A3GE 2R92E 4A3LE 4A3CE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3B E;  3M3Y E;  4BY7 E;  3HOZ E;  3K7A E;  1I50 E;  4A3I E;  5M3F E;  2JA7 E;  3S17 E;  2PMZ H;  5FJ8 E;  5C4J E;  3GTL E;  3I4N E;  2NVY E;  4C3J E;  1Y1W E;  4A3D E;  3GTQ E;  4Y52 E;  4A3E E;  2NVQ E;  1TWH E;  2R7Z E;  4C3I E;  1TWG E;  4Y7N E;  3I4M E;  3H0G E;  4BXX E;  2Y0S H;  4BY1 E;  2NVT E;  3S16 E;  1Y1V E;  5M5Y E;  4BBR E;  3GTJ E;  3S1R E;  1EIK A;  3PO3 E;  3GTG E;  2VUM E;  2JA6 E;  4QIW H;  1TWA E;  2JA8 E;  4X6A E;  3FKI E;  1DZF A;  5IP9 E;  5M5W E;  4A3M E;  2YU9 E;  4C3H E;  1K83 E;  3S14 E;  5C44 E;  4BBS E;  5IYB E;  1SFO E;  5FLM E;  3S2D E;  4A3F E;  3H3V F;  1TWC E;  5C3E E;  2B63 E;  5IYC E;  2WB1 H;  4A3J E;  2R93 E;  3CQZ E;  3HKZ H;  5M3M E;  3S2H E;  3GTO E;  3HOX E;  4AYB H;  3RZD E;  3RZO E;  2JA5 E;  3GTK E;  3HOY E;  3S1N E;  3HOV E;  5C4X E;  1TWF E;  3GTM E;  3PO2 E;  5IYD E;  3M4O E;  3GTP E;  2E2I E;  1R9T E;  1I6H E;  3S15 E;  1WCM E;  2E2H E;  3S1Q E;  5M5X E;  3S1M E;  3HOU E;  4A93 E;  1I3Q E;  4A3K E;  4C2M E;  2E2J E;  3HOW E;  5IP7 E;  2NVX E;  2WAQ H;  4A3G E;  2R92 E;  4A3L E;  4A3C E; 
#chains in the Genus database with same CATH topology
 4MEY E;  4A3B E;  3M3Y E;  4BY7 E;  2WAQ K;  3RZD F;  3RZO F;  3HOZ E;  3S14 F;  4MQ9 E;  5C44 F;  3K7A E;  3HOV F;  1I50 E;  3S1N F;  5C4X F;  4A3I E;  3GTM F;  5M3F E;  2JA7 E;  3PO2 F;  5IYD F;  3M4O F;  4Q5S E;  2E2I F;  1R9T F;  4G7Z E;  1I6H F;  3GTP F;  4JK1 E;  4OIR E;  3S15 F;  3S17 E;  2PMZ H;  1QKL A;  5FJ8 E;  5C4J E;  1WCM F;  3GTL E;  2E2H F;  3I4N E;  2NVY E;  3WOD E;  1YNN K;  2B63 F;  4KMU E;  3S1M F;  3S1Q F;  4YFN E;  4A93 F;  1I3Q F;  4C3J E;  2R93 F;  3CQZ F;  4A3K F;  1Y1W E;  4C2M F;  2PMZ K;  4A3D E;  5IP7 F;  5M3M F;  2NVX F;  2PPB E;  3GTQ E;  4Y52 E;  4A3G F;  2A6E E;  4A3E E;  2R92 F;  4XLP E;  2NVQ E;  1TWH E;  2R7Z E;  3S2H F;  4A3C F;  4C3I E;  3HOX F;  1TWG E;  4Y7N E;  3I4M E;  4Q4Z E;  4BY7 F;  2A68 E;  3H0G E;  4BXX E;  2Y0S H;  2A69 E;  3K7A F;  2JA5 F;  1I50 F;  4BY1 E;  2O5I E;  2NVT E;  4A3I F;  3S16 E;  1Y1V E;  5M5Y E;  4BBR E;  3GTJ E;  3GTK F;  3HOY F;  1TWF F;  3S1R E;  4OIO E;  5E17 E;  1EIK A;  3PO3 E;  3S17 F;  4YFK E;  3GTG E;  2VUM E;  2JA6 E;  3GTL F;  2NVY F;  4QIW H;  1TWA E;  1YNJ K;  2BE5 E;  5M5X F;  2JA8 E;  3HOU F;  4X6A E;  3FKI E;  1Y1W F;  3GTQ F;  2E2J F;  1DZF A;  4Y52 F;  3HOW F;  4A3E F;  5IP9 E;  5M5W E;  4QIW K;  4A3M E;  2Y0S I;  2YU9 E;  4C3H E;  3DXJ E;  4XSZ E;  4C3I F;  4A3L F;  4Y7N F;  4G7O E;  4G7H E;  4GZY E;  4A3B F;  1K83 E;  3S14 E;  3M3Y F;  4BXX F;  5E18 E;  5C44 E;  5IPL E;  3HOZ F;  1SMY E;  2O5J E;  4BBS E;  2KRX A;  4LLG E;  5IYB E;  1Y1V F;  5M5Y F;  3GTJ F;  1SFO E;  1ZYR E;  5FLM E;  4MEX E;  3S16 F;  3S1R F;  5M3F F;  3S2D E;  2JA7 F;  5D4C E;  4A3F E;  3H3V F;  2CW0 E;  1TWC E;  5C3E E;  2VUM F;  2B63 E;  5IYC E;  5FJ8 F;  5C4J F;  2WB1 H;  4KN7 E;  3I4N F;  4OIQ E;  4A3J E;  5BYH E;  2JA8 F;  2R93 E;  4OIN E;  3CQZ E;  4X6A F;  3HKZ H;  3EQL E;  5M3M E;  4C3J F;  4YFX E;  5D4D E;  4LJZ E;  1I6V E;  4A3D F;  5IP9 F;  4A3M F;  4ZH4 E;  3S2H E;  4C3H F;  3GTO E;  1IW7 E;  1TWH F;  3HOX E;  3HKZ K;  4AYB H;  2A6H E;  2NVQ F;  2R7Z F;  5TMC E;  1TWG F;  1K83 F;  3I4M F;  3RZD E;  3RZO E;  3H0G F;  2JA5 E;  4BBS F;  3GTK E;  3HOY E;  4KN4 E;  5IYB F;  3S1N E;  3HOV E;  4AYB K;  5C4X E;  4BY1 F;  1TWF E;  3GTM E;  5FLM F;  1SFO F;  2NVT F;  3PO2 E;  2WB1 I;  4BBR F;  5IYD E;  3S2D F;  1HQM E;  4OIP E;  3M4O E;  3GTP E;  2E2I E;  1R9T E;  1I6H E;  4A3F F;  3S15 E;  1TWC F;  5C3E F;  2YU9 F;  4LK1 E;  3PO3 F;  5D4E E;  1WCM E;  5IYC F;  3GTG F;  2E2H E;  4XSX E;  2JA6 F;  3S1Q E;  4A3J F;  5M5X E;  3S1M E;  4YG2 E;  5TMF E;  4XLN E;  1TWA F;  3HOU E;  4A93 E;  1I3Q E;  3H3V G;  4A3K E;  4C2M E;  2E2J E;  3FKI F;  3HOW E;  5IP7 E;  2NVX E;  2WAQ H;  4A3G E;  2R92 E;  5M5W F;  4LK0 E;  3GTO F;  4A3L E;  4A3C E; 
#chains in the Genus database with same CATH homology
 4A3B E;  3M3Y E;  4BY7 E;  3HOZ E;  3K7A E;  1I50 E;  4A3I E;  5M3F E;  2JA7 E;  3S17 E;  2PMZ H;  5FJ8 E;  5C4J E;  3GTL E;  3I4N E;  2NVY E;  4C3J E;  1Y1W E;  4A3D E;  3GTQ E;  4Y52 E;  4A3E E;  2NVQ E;  1TWH E;  2R7Z E;  4C3I E;  1TWG E;  4Y7N E;  3I4M E;  3H0G E;  4BXX E;  2Y0S H;  4BY1 E;  2NVT E;  3S16 E;  1Y1V E;  5M5Y E;  4BBR E;  3GTJ E;  3S1R E;  1EIK A;  3PO3 E;  3GTG E;  2VUM E;  2JA6 E;  4QIW H;  1TWA E;  2JA8 E;  4X6A E;  3FKI E;  1DZF A;  5IP9 E;  5M5W E;  4A3M E;  2YU9 E;  4C3H E;  1K83 E;  3S14 E;  5C44 E;  4BBS E;  5IYB E;  1SFO E;  5FLM E;  3S2D E;  4A3F E;  3H3V F;  1TWC E;  5C3E E;  2B63 E;  5IYC E;  2WB1 H;  4A3J E;  2R93 E;  3CQZ E;  3HKZ H;  5M3M E;  3S2H E;  3GTO E;  3HOX E;  4AYB H;  3RZD E;  3RZO E;  2JA5 E;  3GTK E;  3HOY E;  3S1N E;  3HOV E;  5C4X E;  1TWF E;  3GTM E;  3PO2 E;  5IYD E;  3M4O E;  3GTP E;  2E2I E;  1R9T E;  1I6H E;  3S15 E;  1WCM E;  2E2H E;  3S1Q E;  5M5X E;  3S1M E;  3HOU E;  4A93 E;  1I3Q E;  4A3K E;  4C2M E;  2E2J E;  3HOW E;  5IP7 E;  2NVX E;  2WAQ H;  4A3G E;  2R92 E;  4A3L E;  4A3C E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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