3I4NE

8-oxoguanine containing rna polymerase ii elongation complex e
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of transcriptional mutagenesis at 8-oxoguanine
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 47
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3i4nE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3i4nE02
5FLME 3RZOE 3RZDE 3PO3E 3S2HE 5M5WE 3HOZE 1I3QE 2R7ZE 4A3FE 4A3GE 5M5XE 3GTKE 5C4XE 1TWCE 4A3EE 5IYDE 1Y1WE 2PMZH 3H0GE 3GTQE 2R93E 3CQZE 3FKIE 5FJ8E 2R92E 4A3BE 2WAQH 3GTGE 4BBSE 4BY7E 3HOYE 3S2DE 2YU9E 5IP7E 2NVYE 5M3FE 4BY1E 1TWHE 1SFOE 4A3ME 2Y0SH 4AYBH 4A3IE 3K7AE 2NVXE 2NVTE 1WCME 5IYCE 2E2JE 5C4JE 4A3KE 2E2IE 4Y7NE 4BXXE 3I4ME 4C3IE 4X6AE 3M4OE 2WB1H 4QIWH 2JA5E 3PO2E 5M5YE 5M3ME 2VUME 1Y1VE 2JA7E 4A93E 2JA6E 4BBRE 3S1ME 1TWAE 1R9TE 3GTJE 3GTME 3S16E 1TWFE 3H3VF 1TWGE 3GTPE 3HOWE 1I50E 3GTOE 4A3JE 5IP9E 1I6HE 1K83E 3S14E 4Y52E 3HKZH 3GTLE 3HOXE 2E2HE 3I4NE 2NVQE 3S1QE 3HOUE 3M3YE 1DZFA 5C3EE 3HOVE 4A3DE 5C44E 4C3JE 3S17E 2B63E 3S1RE 4A3LE 5IYBE 3S15E 4C2ME 4A3CE 4C3HE 1EIKA 2JA8E 3S1NE
chains in the Genus database with same CATH superfamily
5FLME 3RZOE 3S14F 3RZDE 3PO3E 4OIOE 3S2HE 5M5WE 3HOZE 1I3QE 2R7ZE 4Y52F 2JA5F 4A3FE 4A3GE 3GTLF 4OIRE 2O5IE 5M5XE 3I4NF 3HKZK 3GTKE 5C4XE 1Y1VF 2NVQF 4XLPE 2A6EE 3S1QF 1TWCE 4A3EE 5IYDE 2Y0SI 2CW0E 1Y1WE 2PMZH 3H0GE 3GTQE 2R93E 3HOUF 1TWAF 3M3YF 3CQZE 3FKIE 5FJ8E 2R92E 4A3BE 2WAQH 3GTGE 5BYHE 5C44F 4BBSE 4BY7E 3HOYE 1TWFF 4C3JF 1TWGF 3GTOF 5D4CE 3S17F 4G7OE 2B63F 2PMZK 4A3LF 3S2DE 4A3JF 3S15F 4Q4ZE 2YU9E 5IP7E 2NVYE 5M3FE 4BY1E 2WB1I 4C2MF 4A3CF 1TWHE 1SFOE 4C3HF 4XLNE 5E18E 4G7ZE 4A3ME 3WODE 2Y0SH 4G7HE 4AYBH 5FLMF 4A3IE 3RZOF 3RZDF 2A69E 4JK1E 3HOXF 2E2HF 3K7AE 3PO3F 2NVXE 3HOZF 1I3QF 1YNNK 2NVTE 4A3GF 1IW7E 1WCME 5IYCE 2E2JE 5D4DE 5C4JE 4XSZE 4A3KE 3GTKF 2E2IE 5C4XF 4YG2E 4AYBK 4Y7NE 4BXXE 3I4ME 4C3IE 4X6AE 3M4OE 1TWCF 5C3EF 4A3EF 3HOVF 3H3VG 4A3DF 3H0GF 4OIPE 3GTQF 2WB1H 4QIWH 3CQZF 3FKIF 5TMFE 4YFNE 5IPLE 2R92F 2JA5E 3PO2E 1SMYE 4Q5SE 3S1RF 4A3BF 5M5YE 5IYBF 3GTGF 4BY7F 5M3ME 5TMCE 2VUME 1HQME 1ZYRE 1Y1VE 2JA7E 2WAQK 4A93E 2JA6E 4KMUE 4QIWK 1I6VE 3S2DF 4BBRE 5IP7F 2NVYF 4LJZE 3S1ME 4LK1E 4LLGE 4BY1F 1TWAE 2JA8F 1R9TE 3S1NF 2BE5E 3GTJE 3GTME 1TWHF 1SFOF 3S2HF 5M5WF 2KRXA 3S16E 2R7ZF 1TWFE 2A68E 3EQLE 4A3FF 3H3VF 1TWGE 3GTPE 3HOWE 1I50E 3GTOE 4A3IF 5M5XF 3K7AF 4XSXE 4A3JE 2NVXF 4OIQE 1QKLA 2NVTF 2PPBE 5IP9E 1WCMF 5IYCF 2E2JF 1I6HE 2O5JE 5IYDF 1K83E 4KN4E 3S14E 5C4JF 4KN7E 1Y1WF 2R93F 2E2IF 4Y7NF 5FJ8F 3I4MF 4BXXF 4Y52E 3HKZH 4C3IF 4X6AF 3M4OF 3GTLE 3HOXE 2E2HE 4BBSF 5D4EE 3I4NE 3HOYF 5E17E 3PO2F 4GZYE 2NVQE 4MEYE 5M5YF 3S1QE 5M3MF 2YU9F 2VUMF 3HOUE 5M3FF 2JA7F 3M3YE 4A93F 1DZFA 2JA6F 5C3EE 3HOVE 4A3DE 4BBRF 4ZH4E 3S1MF 5C44E 4LK0E 4A3MF 4C3JE 1R9TF 4YFXE 3S17E 3GTJF 3GTMF 2B63E 3S1RE 3DXJE 4A3LE 5IYBE 3S15E 3S16F 4YFKE 3GTPF 1I50F 3HOWF 2A6HE 4C2ME 4A3CE 4MEXE 4A3KF 4C3HE 1YNJK 4MQ9E 2JA8E 5IP9F 4OINE 1EIKA 1I6HF 3S1NE 1K83F
chains in the Genus database with same CATH topology
5FLME 3RZOE 3RZDE 3PO3E 3S2HE 5M5WE 3HOZE 1I3QE 2R7ZE 4A3FE 4A3GE 5M5XE 3GTKE 5C4XE 1TWCE 4A3EE 5IYDE 1Y1WE 2PMZH 3H0GE 3GTQE 2R93E 3CQZE 3FKIE 5FJ8E 2R92E 4A3BE 2WAQH 3GTGE 4BBSE 4BY7E 3HOYE 3S2DE 2YU9E 5IP7E 2NVYE 5M3FE 4BY1E 1TWHE 1SFOE 4A3ME 2Y0SH 4AYBH 4A3IE 3K7AE 2NVXE 2NVTE 1WCME 5IYCE 2E2JE 5C4JE 4A3KE 2E2IE 4Y7NE 4BXXE 3I4ME 4C3IE 4X6AE 3M4OE 2WB1H 4QIWH 2JA5E 3PO2E 5M5YE 5M3ME 2VUME 1Y1VE 2JA7E 4A93E 2JA6E 4BBRE 3S1ME 1TWAE 1R9TE 3GTJE 3GTME 3S16E 1TWFE 3H3VF 1TWGE 3GTPE 3HOWE 1I50E 3GTOE 4A3JE 5IP9E 1I6HE 1K83E 3S14E 4Y52E 3HKZH 3GTLE 3HOXE 2E2HE 3I4NE 2NVQE 3S1QE 3HOUE 3M3YE 1DZFA 5C3EE 3HOVE 4A3DE 5C44E 4C3JE 3S17E 2B63E 3S1RE 4A3LE 5IYBE 3S15E 4C2ME 4A3CE 4C3HE 1EIKA 2JA8E 3S1NE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FLM E;  3RZO E;  3RZD E;  3PO3 E;  3S2H E;  5M5W E;  3HOZ E;  1I3Q E;  2R7Z E;  4A3F E;  4A3G E;  5M5X E;  3GTK E;  5C4X E;  1TWC E;  4A3E E;  5IYD E;  1Y1W E;  2PMZ H;  3H0G E;  3GTQ E;  2R93 E;  3CQZ E;  3FKI E;  5FJ8 E;  2R92 E;  4A3B E;  2WAQ H;  3GTG E;  4BBS E;  4BY7 E;  3HOY E;  3S2D E;  2YU9 E;  5IP7 E;  2NVY E;  5M3F E;  4BY1 E;  1TWH E;  1SFO E;  4A3M E;  2Y0S H;  4AYB H;  4A3I E;  3K7A E;  2NVX E;  2NVT E;  1WCM E;  5IYC E;  2E2J E;  5C4J E;  4A3K E;  2E2I E;  4Y7N E;  4BXX E;  3I4M E;  4C3I E;  4X6A E;  3M4O E;  2WB1 H;  4QIW H;  2JA5 E;  3PO2 E;  5M5Y E;  5M3M E;  2VUM E;  1Y1V E;  2JA7 E;  4A93 E;  2JA6 E;  4BBR E;  3S1M E;  1TWA E;  1R9T E;  3GTJ E;  3GTM E;  3S16 E;  1TWF E;  3H3V F;  1TWG E;  3GTP E;  3HOW E;  1I50 E;  3GTO E;  4A3J E;  5IP9 E;  1I6H E;  1K83 E;  3S14 E;  4Y52 E;  3HKZ H;  3GTL E;  3HOX E;  2E2H E;  3I4N E;  2NVQ E;  3S1Q E;  3HOU E;  3M3Y E;  1DZF A;  5C3E E;  3HOV E;  4A3D E;  5C44 E;  4C3J E;  3S17 E;  2B63 E;  3S1R E;  4A3L E;  5IYB E;  3S15 E;  4C2M E;  4A3C E;  4C3H E;  1EIK A;  2JA8 E;  3S1N E; 
#chains in the Genus database with same CATH topology
 5FLM E;  3RZO E;  3S14 F;  3RZD E;  3PO3 E;  4OIO E;  3S2H E;  5M5W E;  3HOZ E;  1I3Q E;  2R7Z E;  4Y52 F;  2JA5 F;  4A3F E;  4A3G E;  3GTL F;  4OIR E;  2O5I E;  5M5X E;  3I4N F;  3HKZ K;  3GTK E;  5C4X E;  1Y1V F;  2NVQ F;  4XLP E;  2A6E E;  3S1Q F;  1TWC E;  4A3E E;  5IYD E;  2Y0S I;  2CW0 E;  1Y1W E;  2PMZ H;  3H0G E;  3GTQ E;  2R93 E;  3HOU F;  1TWA F;  3M3Y F;  3CQZ E;  3FKI E;  5FJ8 E;  2R92 E;  4A3B E;  2WAQ H;  3GTG E;  5BYH E;  5C44 F;  4BBS E;  4BY7 E;  3HOY E;  1TWF F;  4C3J F;  1TWG F;  3GTO F;  5D4C E;  3S17 F;  4G7O E;  2B63 F;  2PMZ K;  4A3L F;  3S2D E;  4A3J F;  3S15 F;  4Q4Z E;  2YU9 E;  5IP7 E;  2NVY E;  5M3F E;  4BY1 E;  2WB1 I;  4C2M F;  4A3C F;  1TWH E;  1SFO E;  4C3H F;  4XLN E;  5E18 E;  4G7Z E;  4A3M E;  3WOD E;  2Y0S H;  4G7H E;  4AYB H;  5FLM F;  4A3I E;  3RZO F;  3RZD F;  2A69 E;  4JK1 E;  3HOX F;  2E2H F;  3K7A E;  3PO3 F;  2NVX E;  3HOZ F;  1I3Q F;  1YNN K;  2NVT E;  4A3G F;  1IW7 E;  1WCM E;  5IYC E;  2E2J E;  5D4D E;  5C4J E;  4XSZ E;  4A3K E;  3GTK F;  2E2I E;  5C4X F;  4YG2 E;  4AYB K;  4Y7N E;  4BXX E;  3I4M E;  4C3I E;  4X6A E;  3M4O E;  1TWC F;  5C3E F;  4A3E F;  3HOV F;  3H3V G;  4A3D F;  3H0G F;  4OIP E;  3GTQ F;  2WB1 H;  4QIW H;  3CQZ F;  3FKI F;  5TMF E;  4YFN E;  5IPL E;  2R92 F;  2JA5 E;  3PO2 E;  1SMY E;  4Q5S E;  3S1R F;  4A3B F;  5M5Y E;  5IYB F;  3GTG F;  4BY7 F;  5M3M E;  5TMC E;  2VUM E;  1HQM E;  1ZYR E;  1Y1V E;  2JA7 E;  2WAQ K;  4A93 E;  2JA6 E;  4KMU E;  4QIW K;  1I6V E;  3S2D F;  4BBR E;  5IP7 F;  2NVY F;  4LJZ E;  3S1M E;  4LK1 E;  4LLG E;  4BY1 F;  1TWA E;  2JA8 F;  1R9T E;  3S1N F;  2BE5 E;  3GTJ E;  3GTM E;  1TWH F;  1SFO F;  3S2H F;  5M5W F;  2KRX A;  3S16 E;  2R7Z F;  1TWF E;  2A68 E;  3EQL E;  4A3F F;  3H3V F;  1TWG E;  3GTP E;  3HOW E;  1I50 E;  3GTO E;  4A3I F;  5M5X F;  3K7A F;  4XSX E;  4A3J E;  2NVX F;  4OIQ E;  1QKL A;  2NVT F;  2PPB E;  5IP9 E;  1WCM F;  5IYC F;  2E2J F;  1I6H E;  2O5J E;  5IYD F;  1K83 E;  4KN4 E;  3S14 E;  5C4J F;  4KN7 E;  1Y1W F;  2R93 F;  2E2I F;  4Y7N F;  5FJ8 F;  3I4M F;  4BXX F;  4Y52 E;  3HKZ H;  4C3I F;  4X6A F;  3M4O F;  3GTL E;  3HOX E;  2E2H E;  4BBS F;  5D4E E;  3I4N E;  3HOY F;  5E17 E;  3PO2 F;  4GZY E;  2NVQ E;  4MEY E;  5M5Y F;  3S1Q E;  5M3M F;  2YU9 F;  2VUM F;  3HOU E;  5M3F F;  2JA7 F;  3M3Y E;  4A93 F;  1DZF A;  2JA6 F;  5C3E E;  3HOV E;  4A3D E;  4BBR F;  4ZH4 E;  3S1M F;  5C44 E;  4LK0 E;  4A3M F;  4C3J E;  1R9T F;  4YFX E;  3S17 E;  3GTJ F;  3GTM F;  2B63 E;  3S1R E;  3DXJ E;  4A3L E;  5IYB E;  3S15 E;  3S16 F;  4YFK E;  3GTP F;  1I50 F;  3HOW F;  2A6H E;  4C2M E;  4A3C E;  4MEX E;  4A3K F;  4C3H E;  1YNJ K;  4MQ9 E;  2JA8 E;  5IP9 F;  4OIN E;  1EIK A;  1I6H F;  3S1N E;  1K83 F; 
#chains in the Genus database with same CATH homology
 5FLM E;  3RZO E;  3RZD E;  3PO3 E;  3S2H E;  5M5W E;  3HOZ E;  1I3Q E;  2R7Z E;  4A3F E;  4A3G E;  5M5X E;  3GTK E;  5C4X E;  1TWC E;  4A3E E;  5IYD E;  1Y1W E;  2PMZ H;  3H0G E;  3GTQ E;  2R93 E;  3CQZ E;  3FKI E;  5FJ8 E;  2R92 E;  4A3B E;  2WAQ H;  3GTG E;  4BBS E;  4BY7 E;  3HOY E;  3S2D E;  2YU9 E;  5IP7 E;  2NVY E;  5M3F E;  4BY1 E;  1TWH E;  1SFO E;  4A3M E;  2Y0S H;  4AYB H;  4A3I E;  3K7A E;  2NVX E;  2NVT E;  1WCM E;  5IYC E;  2E2J E;  5C4J E;  4A3K E;  2E2I E;  4Y7N E;  4BXX E;  3I4M E;  4C3I E;  4X6A E;  3M4O E;  2WB1 H;  4QIW H;  2JA5 E;  3PO2 E;  5M5Y E;  5M3M E;  2VUM E;  1Y1V E;  2JA7 E;  4A93 E;  2JA6 E;  4BBR E;  3S1M E;  1TWA E;  1R9T E;  3GTJ E;  3GTM E;  3S16 E;  1TWF E;  3H3V F;  1TWG E;  3GTP E;  3HOW E;  1I50 E;  3GTO E;  4A3J E;  5IP9 E;  1I6H E;  1K83 E;  3S14 E;  4Y52 E;  3HKZ H;  3GTL E;  3HOX E;  2E2H E;  3I4N E;  2NVQ E;  3S1Q E;  3HOU E;  3M3Y E;  1DZF A;  5C3E E;  3HOV E;  4A3D E;  5C44 E;  4C3J E;  3S17 E;  2B63 E;  3S1R E;  4A3L E;  5IYB E;  3S15 E;  4C2M E;  4A3C E;  4C3H E;  1EIK A;  2JA8 E;  3S1N E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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