3M3YE

Rna polymerase ii elongation complex c
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 50
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3m3yE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3m3yE02
5C4XE 4BBRE 3GTKE 2E2IE 4C3IE 2JA6E 4Y52E 3H3VF 1WCME 3M4OE 5M5XE 4C2ME 5C4JE 3GTME 5IYDE 2E2JE 3GTGE 4BBSE 3S16E 1I6HE 4A3DE 4A3BE 5M3FE 3GTQE 4X6AE 4C3JE 3S14E 4QIWH 1TWFE 2R7ZE 5M5YE 2WB1H 1Y1VE 3S1NE 3HOXE 1R9TE 2NVTE 2VUME 2Y0SH 4AYBH 1TWAE 4A3LE 4A3FE 3HOZE 3PO2E 3HOVE 3CQZE 3M3YE 2YU9E 4A3KE 5IYBE 5M5WE 3PO3E 3HKZH 2JA8E 3S1QE 5C44E 3K7AE 3RZDE 3I4NE 1EIKA 3HOUE 1TWHE 5M3ME 4BY7E 3HOWE 1I50E 1TWGE 4A3IE 2R93E 2JA5E 5IP7E 3H0GE 3HOYE 1TWCE 4BY1E 4C3HE 3S1ME 4A3ME 1Y1WE 2JA7E 4A3GE 5FJ8E 3GTJE 4BXXE 1DZFA 3S15E 3RZOE 2PMZH 3S2DE 4A3CE 3S1RE 3GTLE 4A93E 2B63E 2WAQH 2NVYE 2NVXE 3GTOE 5FLME 2E2HE 3S17E 2R92E 4A3JE 4A3EE 3I4ME 1K83E 4Y7NE 5IP9E 3S2HE 5C3EE 3FKIE 3GTPE 5IYCE 1I3QE 2NVQE 1SFOE
chains in the Genus database with same CATH superfamily
3HOWF 3S17F 5C4XE 4BBRE 4OIQE 3GTKE 2E2IE 4C3IE 2JA6E 4Y52E 3H3VF 4YFXE 4A3IF 1K83F 2A68E 4LK1E 2PMZK 5IP7F 5IP9F 3HOYF 1WCME 3M4OE 5M5XE 4MQ9E 4C3HF 4C2ME 5C4JE 3GTME 4A3MF 2WAQK 4ZH4E 3S1MF 4G7OE 5FJ8F 5IYDE 3GTJF 4A3GF 2E2JE 4BXXF 3GTGE 4BBSE 3S16E 1I6HE 3S15F 4A3DE 4A3BE 5M3FE 3GTQE 4X6AE 2A69E 3S2DF 3DXJE 4A3CF 2O5JE 3GTKF 4C3JE 2WB1I 2PPBE 3S14E 2A6HE 2NVYF 4KMUE 4QIWH 1TWFE 2R7ZE 2NVXF 5M5YE 2WB1H 1Y1VE 4C2MF 3GTMF 3S1NE 4G7ZE 2E2HF 2Y0SI 3HOXE 1R9TE 4BBSF 2R92F 2NVTE 4A3DF 2VUME 4JK1E 5M3FF 2Y0SH 4A3JF 4A3EF 3GTQF 3I4MF 4AYBH 4Y7NF 1TWAE 2O5IE 4OIPE 4C3JF 3S2HF 4A3LE 4OIOE 4A3FE 4Q4ZE 4XSZE 5C3EF 3HOZE 4KN7E 1TWFF 3FKIF 3GTPF 3PO2E 1I3QF 5D4EE 5IYCF 3HOVE 5TMFE 4MEXE 3CQZE 4YFNE 3M3YE 1SFOF 2NVQF 2YU9E 5C4XF 4BBRF 4A3KE 5IPLE 5IYBE 2E2IF 5M5WE 3PO3E 4C3IF 2JA6F 4MEYE 4Y52F 2A6EE 1IW7E 3HKZH 2JA8E 3S1QE 4XLPE 1TWAF 4Q5SE 1WCMF 5C44E 3K7AE 3M4OF 5E17E 4XLNE 3RZDE 3I4NE 5M5XF 1EIKA 2BE5E 5C4JF 3PO2F 5IYDF 2E2JF 3HOVF 3HOUE 1YNNK 3GTGF 1TWHE 3CQZF 1I6HF 3S16F 5M3ME 4LLGE 4BY7E 5FLMF 4A3BF 4X6AF 4A3KF 3HOWE 4OIRE 4XSXE 4YFKE 1I50E 1TWGE 5E18E 3S14F 4AYBK 4A3IE 1YNJK 2R7ZF 5C44F 5M5YF 2R93E 1Y1VF 2JA5E 5IP7E 3H0GE 3RZDF 3HOYE 1TWCE 1SMYE 3S1NF 4GZYE 4BY1E 1QKLA 4C3HE 3S1ME 3HOXF 4A3ME 1R9TF 1Y1WE 2NVTF 2JA7E 4A3GE 5FJ8E 3GTJE 5M3MF 2VUMF 4BXXE 2CW0E 1DZFA 4YG2E 4OINE 3S15E 3RZOE 2PMZH 3S2DE 4A3CE 3EQLE 3S1RE 1I50F 1TWGF 4A3FF 4A3LF 3GTLE 3HOZF 3HKZK 2KRXA 4A93E 2B63E 2R93F 2WAQH 2NVYE 4KN4E 4QIWK 2JA5F 3H0GF 1TWCF 2NVXE 5BYHE 3M3YF 1I6VE 3GTOE 1ZYRE 4BY1F 2YU9F 5FLME 1Y1WF 2JA7F 2E2HE 3S17E 5IYBF 5M5WF 3PO3F 4G7HE 5D4CE 2R92E 1HQME 2JA8F 3WODE 3S1QF 4A3JE 4A3EE 3I4ME 3RZOF 5TMCE 1K83E 3K7AF 4Y7NE 3S1RF 3I4NF 5IP9E 3GTLF 4A93F 3S2HE 2B63F 5C3EE 5D4DE 3HOUF 3FKIE 3GTPE 5IYCE 1I3QE 1TWHF 4LK0E 3GTOF 4BY7F 4LJZE 2NVQE 1SFOE 3H3VG
chains in the Genus database with same CATH topology
5C4XE 4BBRE 3GTKE 2E2IE 4C3IE 2JA6E 4Y52E 3H3VF 1WCME 3M4OE 5M5XE 4C2ME 5C4JE 3GTME 5IYDE 2E2JE 3GTGE 4BBSE 3S16E 1I6HE 4A3DE 4A3BE 5M3FE 3GTQE 4X6AE 4C3JE 3S14E 4QIWH 1TWFE 2R7ZE 5M5YE 2WB1H 1Y1VE 3S1NE 3HOXE 1R9TE 2NVTE 2VUME 2Y0SH 4AYBH 1TWAE 4A3LE 4A3FE 3HOZE 3PO2E 3HOVE 3CQZE 3M3YE 2YU9E 4A3KE 5IYBE 5M5WE 3PO3E 3HKZH 2JA8E 3S1QE 5C44E 3K7AE 3RZDE 3I4NE 1EIKA 3HOUE 1TWHE 5M3ME 4BY7E 3HOWE 1I50E 1TWGE 4A3IE 2R93E 2JA5E 5IP7E 3H0GE 3HOYE 1TWCE 4BY1E 4C3HE 3S1ME 4A3ME 1Y1WE 2JA7E 4A3GE 5FJ8E 3GTJE 4BXXE 1DZFA 3S15E 3RZOE 2PMZH 3S2DE 4A3CE 3S1RE 3GTLE 4A93E 2B63E 2WAQH 2NVYE 2NVXE 3GTOE 5FLME 2E2HE 3S17E 2R92E 4A3JE 4A3EE 3I4ME 1K83E 4Y7NE 5IP9E 3S2HE 5C3EE 3FKIE 3GTPE 5IYCE 1I3QE 2NVQE 1SFOE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C4X E;  4BBR E;  3GTK E;  2E2I E;  4C3I E;  2JA6 E;  4Y52 E;  3H3V F;  1WCM E;  3M4O E;  5M5X E;  4C2M E;  5C4J E;  3GTM E;  5IYD E;  2E2J E;  3GTG E;  4BBS E;  3S16 E;  1I6H E;  4A3D E;  4A3B E;  5M3F E;  3GTQ E;  4X6A E;  4C3J E;  3S14 E;  4QIW H;  1TWF E;  2R7Z E;  5M5Y E;  2WB1 H;  1Y1V E;  3S1N E;  3HOX E;  1R9T E;  2NVT E;  2VUM E;  2Y0S H;  4AYB H;  1TWA E;  4A3L E;  4A3F E;  3HOZ E;  3PO2 E;  3HOV E;  3CQZ E;  3M3Y E;  2YU9 E;  4A3K E;  5IYB E;  5M5W E;  3PO3 E;  3HKZ H;  2JA8 E;  3S1Q E;  5C44 E;  3K7A E;  3RZD E;  3I4N E;  1EIK A;  3HOU E;  1TWH E;  5M3M E;  4BY7 E;  3HOW E;  1I50 E;  1TWG E;  4A3I E;  2R93 E;  2JA5 E;  5IP7 E;  3H0G E;  3HOY E;  1TWC E;  4BY1 E;  4C3H E;  3S1M E;  4A3M E;  1Y1W E;  2JA7 E;  4A3G E;  5FJ8 E;  3GTJ E;  4BXX E;  1DZF A;  3S15 E;  3RZO E;  2PMZ H;  3S2D E;  4A3C E;  3S1R E;  3GTL E;  4A93 E;  2B63 E;  2WAQ H;  2NVY E;  2NVX E;  3GTO E;  5FLM E;  2E2H E;  3S17 E;  2R92 E;  4A3J E;  4A3E E;  3I4M E;  1K83 E;  4Y7N E;  5IP9 E;  3S2H E;  5C3E E;  3FKI E;  3GTP E;  5IYC E;  1I3Q E;  2NVQ E;  1SFO E; 
#chains in the Genus database with same CATH topology
 3HOW F;  3S17 F;  5C4X E;  4BBR E;  4OIQ E;  3GTK E;  2E2I E;  4C3I E;  2JA6 E;  4Y52 E;  3H3V F;  4YFX E;  4A3I F;  1K83 F;  2A68 E;  4LK1 E;  2PMZ K;  5IP7 F;  5IP9 F;  3HOY F;  1WCM E;  3M4O E;  5M5X E;  4MQ9 E;  4C3H F;  4C2M E;  5C4J E;  3GTM E;  4A3M F;  2WAQ K;  4ZH4 E;  3S1M F;  4G7O E;  5FJ8 F;  5IYD E;  3GTJ F;  4A3G F;  2E2J E;  4BXX F;  3GTG E;  4BBS E;  3S16 E;  1I6H E;  3S15 F;  4A3D E;  4A3B E;  5M3F E;  3GTQ E;  4X6A E;  2A69 E;  3S2D F;  3DXJ E;  4A3C F;  2O5J E;  3GTK F;  4C3J E;  2WB1 I;  2PPB E;  3S14 E;  2A6H E;  2NVY F;  4KMU E;  4QIW H;  1TWF E;  2R7Z E;  2NVX F;  5M5Y E;  2WB1 H;  1Y1V E;  4C2M F;  3GTM F;  3S1N E;  4G7Z E;  2E2H F;  2Y0S I;  3HOX E;  1R9T E;  4BBS F;  2R92 F;  2NVT E;  4A3D F;  2VUM E;  4JK1 E;  5M3F F;  2Y0S H;  4A3J F;  4A3E F;  3GTQ F;  3I4M F;  4AYB H;  4Y7N F;  1TWA E;  2O5I E;  4OIP E;  4C3J F;  3S2H F;  4A3L E;  4OIO E;  4A3F E;  4Q4Z E;  4XSZ E;  5C3E F;  3HOZ E;  4KN7 E;  1TWF F;  3FKI F;  3GTP F;  3PO2 E;  1I3Q F;  5D4E E;  5IYC F;  3HOV E;  5TMF E;  4MEX E;  3CQZ E;  4YFN E;  3M3Y E;  1SFO F;  2NVQ F;  2YU9 E;  5C4X F;  4BBR F;  4A3K E;  5IPL E;  5IYB E;  2E2I F;  5M5W E;  3PO3 E;  4C3I F;  2JA6 F;  4MEY E;  4Y52 F;  2A6E E;  1IW7 E;  3HKZ H;  2JA8 E;  3S1Q E;  4XLP E;  1TWA F;  4Q5S E;  1WCM F;  5C44 E;  3K7A E;  3M4O F;  5E17 E;  4XLN E;  3RZD E;  3I4N E;  5M5X F;  1EIK A;  2BE5 E;  5C4J F;  3PO2 F;  5IYD F;  2E2J F;  3HOV F;  3HOU E;  1YNN K;  3GTG F;  1TWH E;  3CQZ F;  1I6H F;  3S16 F;  5M3M E;  4LLG E;  4BY7 E;  5FLM F;  4A3B F;  4X6A F;  4A3K F;  3HOW E;  4OIR E;  4XSX E;  4YFK E;  1I50 E;  1TWG E;  5E18 E;  3S14 F;  4AYB K;  4A3I E;  1YNJ K;  2R7Z F;  5C44 F;  5M5Y F;  2R93 E;  1Y1V F;  2JA5 E;  5IP7 E;  3H0G E;  3RZD F;  3HOY E;  1TWC E;  1SMY E;  3S1N F;  4GZY E;  4BY1 E;  1QKL A;  4C3H E;  3S1M E;  3HOX F;  4A3M E;  1R9T F;  1Y1W E;  2NVT F;  2JA7 E;  4A3G E;  5FJ8 E;  3GTJ E;  5M3M F;  2VUM F;  4BXX E;  2CW0 E;  1DZF A;  4YG2 E;  4OIN E;  3S15 E;  3RZO E;  2PMZ H;  3S2D E;  4A3C E;  3EQL E;  3S1R E;  1I50 F;  1TWG F;  4A3F F;  4A3L F;  3GTL E;  3HOZ F;  3HKZ K;  2KRX A;  4A93 E;  2B63 E;  2R93 F;  2WAQ H;  2NVY E;  4KN4 E;  4QIW K;  2JA5 F;  3H0G F;  1TWC F;  2NVX E;  5BYH E;  3M3Y F;  1I6V E;  3GTO E;  1ZYR E;  4BY1 F;  2YU9 F;  5FLM E;  1Y1W F;  2JA7 F;  2E2H E;  3S17 E;  5IYB F;  5M5W F;  3PO3 F;  4G7H E;  5D4C E;  2R92 E;  1HQM E;  2JA8 F;  3WOD E;  3S1Q F;  4A3J E;  4A3E E;  3I4M E;  3RZO F;  5TMC E;  1K83 E;  3K7A F;  4Y7N E;  3S1R F;  3I4N F;  5IP9 E;  3GTL F;  4A93 F;  3S2H E;  2B63 F;  5C3E E;  5D4D E;  3HOU F;  3FKI E;  3GTP E;  5IYC E;  1I3Q E;  1TWH F;  4LK0 E;  3GTO F;  4BY7 F;  4LJZ E;  2NVQ E;  1SFO E;  3H3V G; 
#chains in the Genus database with same CATH homology
 5C4X E;  4BBR E;  3GTK E;  2E2I E;  4C3I E;  2JA6 E;  4Y52 E;  3H3V F;  1WCM E;  3M4O E;  5M5X E;  4C2M E;  5C4J E;  3GTM E;  5IYD E;  2E2J E;  3GTG E;  4BBS E;  3S16 E;  1I6H E;  4A3D E;  4A3B E;  5M3F E;  3GTQ E;  4X6A E;  4C3J E;  3S14 E;  4QIW H;  1TWF E;  2R7Z E;  5M5Y E;  2WB1 H;  1Y1V E;  3S1N E;  3HOX E;  1R9T E;  2NVT E;  2VUM E;  2Y0S H;  4AYB H;  1TWA E;  4A3L E;  4A3F E;  3HOZ E;  3PO2 E;  3HOV E;  3CQZ E;  3M3Y E;  2YU9 E;  4A3K E;  5IYB E;  5M5W E;  3PO3 E;  3HKZ H;  2JA8 E;  3S1Q E;  5C44 E;  3K7A E;  3RZD E;  3I4N E;  1EIK A;  3HOU E;  1TWH E;  5M3M E;  4BY7 E;  3HOW E;  1I50 E;  1TWG E;  4A3I E;  2R93 E;  2JA5 E;  5IP7 E;  3H0G E;  3HOY E;  1TWC E;  4BY1 E;  4C3H E;  3S1M E;  4A3M E;  1Y1W E;  2JA7 E;  4A3G E;  5FJ8 E;  3GTJ E;  4BXX E;  1DZF A;  3S15 E;  3RZO E;  2PMZ H;  3S2D E;  4A3C E;  3S1R E;  3GTL E;  4A93 E;  2B63 E;  2WAQ H;  2NVY E;  2NVX E;  3GTO E;  5FLM E;  2E2H E;  3S17 E;  2R92 E;  4A3J E;  4A3E E;  3I4M E;  1K83 E;  4Y7N E;  5IP9 E;  3S2H E;  5C3E E;  3FKI E;  3GTP E;  5IYC E;  1I3Q E;  2NVQ E;  1SFO E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...