3M7QB

Crystal structure of recombinant kunitz type serine protease inhibitor-1 from the caribbean sea anemone stichodactyla helianthus in complex with bovine pancreatic trypsin
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
61
structure length
61
Chain Sequence
EAEASICSEPKKVGRCKGYFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHQCRAICRALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Stichodactyla helianthus
molecule keywords Cationic trypsin
total genus 10
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 2010-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3m7qB00
2KCRA 4Y10I 3BTWI 1F5RI 3LDJA 4BNRI 1TCPA 1TAWB 4ISLB 1JV8A 1P2NB 2W8XA 1T8NB 2LFLA 1MTND 3BTKI 2R9PE 4NTXB 2M01A 2KNTA 1LD6A 3TGJI 1DTXA 1F7ZI 1ADZA 1T8LB 1P2II 3OTJI 1OA55 3AUHA 3T62D 3D65I 2FTLI 1P2MB 1TPAI 1BUNB 1BF0A 1EAWB 4DTGK 1UUBA 1FAKI 1G6XA 1DENA 2M99A 3U1JE 4Y0ZI 6PTIA 4NTWB 1ZJDB 4BQDA 3OFWA 1K6UA 1QLQA 8PTIA 3UIRC 3BTTI 1BZXI 1EJMB 1KUNA 3BTFI 1D0DA 2TPII 1BRCI 1P2JI 1TOCR 2FI5I 3BTQI 3TPII 1YLCB 1AALA 3BTHI 4DG4C 1BPIA 3WNYA 5C67C 2PTCI 1AAPA 1KIGI 1YC0I 3P95E 4ISOB 5JB4A 1YKTB 1TAPA 2DDIA 3P92E 3BTEI 3FP8I 3FP7J 2HEXA 2ZVXA 1SHPA 2RA3C 1P2OB 3BYBA 4U30W 4PTIA 1ZR0B 4Y0YI 1BHCA 1PITA 5JB6A 2FI3I 2LFKA 1Y62A 1TFXC 4U32X 1BTHP 5JB5A 1D0DB 2J6DA 4Y11I 9PTIA 1DEMA 2UUYB 4NTYB 3UOUB 3AUCA 1T8OB 1UUAA 1NAGA 3GYMI 4BD9B 3AUEA 1KTHA 2JOTA 2TGPI 3L33E 1BZ5A 4ISNB 1JC6A 2KAII 3AUDA 3CI7A 2ODYE 1DTKA 1BIKA 1T7CB 2DDJA 3L3TE 2FTMB 3BTDI 1OA65 3M7QB 1B0CA 1CBWD 1T8MB 4TPII 3BTMI 1BRBI 7PTIA 3TGII 2IJOI 1JV9A 3LDIA 3FP6I 1P2KI 1BPTA 2UUXA 1LD5A 1YLDB 5JB7A 3BTGI 1BTIA 3AUIA 3LDMA 3TGKI 1CO7I 1IRHA 1FANA 1P2QB 3AUBA 1KNTA 5PTIA 2ZJXA 4WWYC 1CA0D 4WXVC 1FY8I 3AUGA 2CA7A 2FI4I
chains in the Genus database with same CATH superfamily
2KCRA 4Y10I 3BTWI 1F5RI 3LDJA 4BNRI 1TCPA 1TAWB 4ISLB 1JV8A 1P2NB 2W8XA 1T8NB 2LFLA 1MTND 3BTKI 2R9PE 4NTXB 2M01A 2KNTA 1LD6A 3TGJI 1DTXA 1F7ZI 1ADZA 1T8LB 1P2II 3OTJI 1OA55 3AUHA 3T62D 3D65I 2FTLI 1P2MB 1TPAI 1BUNB 1BF0A 1EAWB 4DTGK 1UUBA 1FAKI 1G6XA 1DENA 2M99A 3U1JE 4Y0ZI 6PTIA 4NTWB 1ZJDB 4BQDA 3OFWA 1K6UA 1QLQA 8PTIA 3UIRC 3BTTI 1BZXI 1EJMB 1KUNA 3BTFI 1D0DA 2TPII 1BRCI 1P2JI 1TOCR 2FI5I 3BTQI 3TPII 1YLCB 1AALA 3BTHI 4DG4C 1BPIA 3WNYA 5C67C 2PTCI 1AAPA 1KIGI 1YC0I 3P95E 4ISOB 5JB4A 1YKTB 1TAPA 2DDIA 3P92E 3BTEI 3FP8I 3FP7J 2HEXA 2ZVXA 1SHPA 2RA3C 1P2OB 3BYBA 4U30W 4PTIA 1ZR0B 4Y0YI 1BHCA 1PITA 5JB6A 2FI3I 2LFKA 1Y62A 1TFXC 4U32X 1BTHP 5JB5A 1D0DB 2J6DA 4Y11I 9PTIA 1DEMA 2UUYB 4NTYB 3UOUB 3AUCA 1T8OB 1UUAA 1NAGA 3GYMI 4BD9B 3AUEA 1KTHA 2JOTA 2TGPI 3L33E 1BZ5A 4ISNB 1JC6A 2KAII 3AUDA 3CI7A 2ODYE 1DTKA 1BIKA 1T7CB 2DDJA 3L3TE 2FTMB 3BTDI 1OA65 3M7QB 1B0CA 1CBWD 1T8MB 4TPII 3BTMI 1BRBI 7PTIA 3TGII 2IJOI 1JV9A 3LDIA 3FP6I 1P2KI 1BPTA 2UUXA 1LD5A 1YLDB 5JB7A 3BTGI 1BTIA 3AUIA 3LDMA 3TGKI 1CO7I 1IRHA 1FANA 1P2QB 3AUBA 1KNTA 5PTIA 2ZJXA 4WWYC 1CA0D 4WXVC 1FY8I 3AUGA 2CA7A 2FI4I
chains in the Genus database with same CATH topology
2KCRA 4Y10I 3BTWI 1F5RI 3LDJA 4BNRI 1TCPA 1TAWB 4ISLB 1JV8A 1P2NB 2W8XA 1T8NB 2LFLA 1MTND 3BTKI 2R9PE 4NTXB 2M01A 2KNTA 1LD6A 3TGJI 1DTXA 1F7ZI 1ADZA 1T8LB 1P2II 3OTJI 1OA55 3AUHA 3T62D 3D65I 2FTLI 1P2MB 1TPAI 1BUNB 1BF0A 1EAWB 4DTGK 1UUBA 1FAKI 1G6XA 1DENA 2M99A 3U1JE 4Y0ZI 6PTIA 4NTWB 1ZJDB 4BQDA 3OFWA 1K6UA 1QLQA 8PTIA 3UIRC 3BTTI 1BZXI 1EJMB 1KUNA 3BTFI 1D0DA 2TPII 1BRCI 1P2JI 1TOCR 2FI5I 3BTQI 3TPII 1YLCB 1AALA 3BTHI 4DG4C 1BPIA 3WNYA 5C67C 2PTCI 1AAPA 1KIGI 1YC0I 3P95E 4ISOB 5JB4A 1YKTB 1TAPA 2DDIA 3P92E 3BTEI 3FP8I 3FP7J 2HEXA 2ZVXA 1SHPA 2RA3C 1P2OB 3BYBA 4U30W 4PTIA 1ZR0B 4Y0YI 1BHCA 1PITA 5JB6A 2FI3I 2LFKA 1Y62A 1TFXC 4U32X 1BTHP 5JB5A 1D0DB 2J6DA 4Y11I 9PTIA 1DEMA 2UUYB 4NTYB 3UOUB 3AUCA 1T8OB 1UUAA 1NAGA 3GYMI 4BD9B 3AUEA 1KTHA 2JOTA 2TGPI 3L33E 1BZ5A 4ISNB 1JC6A 2KAII 3AUDA 3CI7A 2ODYE 1DTKA 1BIKA 1T7CB 2DDJA 3L3TE 2FTMB 3BTDI 1OA65 3M7QB 1B0CA 1CBWD 1T8MB 4TPII 3BTMI 1BRBI 7PTIA 3TGII 2IJOI 1JV9A 3LDIA 3FP6I 1P2KI 1BPTA 2UUXA 1LD5A 1YLDB 5JB7A 3BTGI 1BTIA 3AUIA 3LDMA 3TGKI 1CO7I 1IRHA 1FANA 1P2QB 3AUBA 1KNTA 5PTIA 2ZJXA 4WWYC 1CA0D 4WXVC 1FY8I 3AUGA 2CA7A 2FI4I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KCR A;  4Y10 I;  3BTW I;  1F5R I;  3LDJ A;  4BNR I;  1TCP A;  1TAW B;  4ISL B;  1JV8 A;  1P2N B;  2W8X A;  1T8N B;  2LFL A;  1MTN D;  3BTK I;  2R9P E;  4NTX B;  2M01 A;  2KNT A;  1LD6 A;  3TGJ I;  1DTX A;  1F7Z I;  1ADZ A;  1T8L B;  1P2I I;  3OTJ I;  1OA5 5;  3AUH A;  3T62 D;  3D65 I;  2FTL I;  1P2M B;  1TPA I;  1BUN B;  1BF0 A;  1EAW B;  4DTG K;  1UUB A;  1FAK I;  1G6X A;  1DEN A;  2M99 A;  3U1J E;  4Y0Z I;  6PTI A;  4NTW B;  1ZJD B;  4BQD A;  3OFW A;  1K6U A;  1QLQ A;  8PTI A;  3UIR C;  3BTT I;  1BZX I;  1EJM B;  1KUN A;  3BTF I;  1D0D A;  2TPI I;  1BRC I;  1P2J I;  1TOC R;  2FI5 I;  3BTQ I;  3TPI I;  1YLC B;  1AAL A;  3BTH I;  4DG4 C;  1BPI A;  3WNY A;  5C67 C;  2PTC I;  1AAP A;  1KIG I;  1YC0 I;  3P95 E;  4ISO B;  5JB4 A;  1YKT B;  1TAP A;  2DDI A;  3P92 E;  3BTE I;  3FP8 I;  3FP7 J;  2HEX A;  2ZVX A;  1SHP A;  2RA3 C;  1P2O B;  3BYB A;  4U30 W;  4PTI A;  1ZR0 B;  4Y0Y I;  1BHC A;  1PIT A;  5JB6 A;  2FI3 I;  2LFK A;  1Y62 A;  1TFX C;  4U32 X;  1BTH P;  5JB5 A;  1D0D B;  2J6D A;  4Y11 I;  9PTI A;  1DEM A;  2UUY B;  4NTY B;  3UOU B;  3AUC A;  1T8O B;  1UUA A;  1NAG A;  3GYM I;  4BD9 B;  3AUE A;  1KTH A;  2JOT A;  2TGP I;  3L33 E;  1BZ5 A;  4ISN B;  1JC6 A;  2KAI I;  3AUD A;  3CI7 A;  2ODY E;  1DTK A;  1BIK A;  1T7C B;  2DDJ A;  3L3T E;  2FTM B;  3BTD I;  1OA6 5;  3M7Q B;  1B0C A;  1CBW D;  1T8M B;  4TPI I;  3BTM I;  1BRB I;  7PTI A;  3TGI I;  2IJO I;  1JV9 A;  3LDI A;  3FP6 I;  1P2K I;  1BPT A;  2UUX A;  1LD5 A;  1YLD B;  5JB7 A;  3BTG I;  1BTI A;  3AUI A;  3LDM A;  3TGK I;  1CO7 I;  1IRH A;  1FAN A;  1P2Q B;  3AUB A;  1KNT A;  5PTI A;  2ZJX A;  4WWY C;  1CA0 D;  4WXV C;  1FY8 I;  3AUG A;  2CA7 A;  2FI4 I; 
#chains in the Genus database with same CATH topology
 2KCR A;  4Y10 I;  3BTW I;  1F5R I;  3LDJ A;  4BNR I;  1TCP A;  1TAW B;  4ISL B;  1JV8 A;  1P2N B;  2W8X A;  1T8N B;  2LFL A;  1MTN D;  3BTK I;  2R9P E;  4NTX B;  2M01 A;  2KNT A;  1LD6 A;  3TGJ I;  1DTX A;  1F7Z I;  1ADZ A;  1T8L B;  1P2I I;  3OTJ I;  1OA5 5;  3AUH A;  3T62 D;  3D65 I;  2FTL I;  1P2M B;  1TPA I;  1BUN B;  1BF0 A;  1EAW B;  4DTG K;  1UUB A;  1FAK I;  1G6X A;  1DEN A;  2M99 A;  3U1J E;  4Y0Z I;  6PTI A;  4NTW B;  1ZJD B;  4BQD A;  3OFW A;  1K6U A;  1QLQ A;  8PTI A;  3UIR C;  3BTT I;  1BZX I;  1EJM B;  1KUN A;  3BTF I;  1D0D A;  2TPI I;  1BRC I;  1P2J I;  1TOC R;  2FI5 I;  3BTQ I;  3TPI I;  1YLC B;  1AAL A;  3BTH I;  4DG4 C;  1BPI A;  3WNY A;  5C67 C;  2PTC I;  1AAP A;  1KIG I;  1YC0 I;  3P95 E;  4ISO B;  5JB4 A;  1YKT B;  1TAP A;  2DDI A;  3P92 E;  3BTE I;  3FP8 I;  3FP7 J;  2HEX A;  2ZVX A;  1SHP A;  2RA3 C;  1P2O B;  3BYB A;  4U30 W;  4PTI A;  1ZR0 B;  4Y0Y I;  1BHC A;  1PIT A;  5JB6 A;  2FI3 I;  2LFK A;  1Y62 A;  1TFX C;  4U32 X;  1BTH P;  5JB5 A;  1D0D B;  2J6D A;  4Y11 I;  9PTI A;  1DEM A;  2UUY B;  4NTY B;  3UOU B;  3AUC A;  1T8O B;  1UUA A;  1NAG A;  3GYM I;  4BD9 B;  3AUE A;  1KTH A;  2JOT A;  2TGP I;  3L33 E;  1BZ5 A;  4ISN B;  1JC6 A;  2KAI I;  3AUD A;  3CI7 A;  2ODY E;  1DTK A;  1BIK A;  1T7C B;  2DDJ A;  3L3T E;  2FTM B;  3BTD I;  1OA6 5;  3M7Q B;  1B0C A;  1CBW D;  1T8M B;  4TPI I;  3BTM I;  1BRB I;  7PTI A;  3TGI I;  2IJO I;  1JV9 A;  3LDI A;  3FP6 I;  1P2K I;  1BPT A;  2UUX A;  1LD5 A;  1YLD B;  5JB7 A;  3BTG I;  1BTI A;  3AUI A;  3LDM A;  3TGK I;  1CO7 I;  1IRH A;  1FAN A;  1P2Q B;  3AUB A;  1KNT A;  5PTI A;  2ZJX A;  4WWY C;  1CA0 D;  4WXV C;  1FY8 I;  3AUG A;  2CA7 A;  2FI4 I; 
#chains in the Genus database with same CATH homology
 2KCR A;  4Y10 I;  3BTW I;  1F5R I;  3LDJ A;  4BNR I;  1TCP A;  1TAW B;  4ISL B;  1JV8 A;  1P2N B;  2W8X A;  1T8N B;  2LFL A;  1MTN D;  3BTK I;  2R9P E;  4NTX B;  2M01 A;  2KNT A;  1LD6 A;  3TGJ I;  1DTX A;  1F7Z I;  1ADZ A;  1T8L B;  1P2I I;  3OTJ I;  1OA5 5;  3AUH A;  3T62 D;  3D65 I;  2FTL I;  1P2M B;  1TPA I;  1BUN B;  1BF0 A;  1EAW B;  4DTG K;  1UUB A;  1FAK I;  1G6X A;  1DEN A;  2M99 A;  3U1J E;  4Y0Z I;  6PTI A;  4NTW B;  1ZJD B;  4BQD A;  3OFW A;  1K6U A;  1QLQ A;  8PTI A;  3UIR C;  3BTT I;  1BZX I;  1EJM B;  1KUN A;  3BTF I;  1D0D A;  2TPI I;  1BRC I;  1P2J I;  1TOC R;  2FI5 I;  3BTQ I;  3TPI I;  1YLC B;  1AAL A;  3BTH I;  4DG4 C;  1BPI A;  3WNY A;  5C67 C;  2PTC I;  1AAP A;  1KIG I;  1YC0 I;  3P95 E;  4ISO B;  5JB4 A;  1YKT B;  1TAP A;  2DDI A;  3P92 E;  3BTE I;  3FP8 I;  3FP7 J;  2HEX A;  2ZVX A;  1SHP A;  2RA3 C;  1P2O B;  3BYB A;  4U30 W;  4PTI A;  1ZR0 B;  4Y0Y I;  1BHC A;  1PIT A;  5JB6 A;  2FI3 I;  2LFK A;  1Y62 A;  1TFX C;  4U32 X;  1BTH P;  5JB5 A;  1D0D B;  2J6D A;  4Y11 I;  9PTI A;  1DEM A;  2UUY B;  4NTY B;  3UOU B;  3AUC A;  1T8O B;  1UUA A;  1NAG A;  3GYM I;  4BD9 B;  3AUE A;  1KTH A;  2JOT A;  2TGP I;  3L33 E;  1BZ5 A;  4ISN B;  1JC6 A;  2KAI I;  3AUD A;  3CI7 A;  2ODY E;  1DTK A;  1BIK A;  1T7C B;  2DDJ A;  3L3T E;  2FTM B;  3BTD I;  1OA6 5;  3M7Q B;  1B0C A;  1CBW D;  1T8M B;  4TPI I;  3BTM I;  1BRB I;  7PTI A;  3TGI I;  2IJO I;  1JV9 A;  3LDI A;  3FP6 I;  1P2K I;  1BPT A;  2UUX A;  1LD5 A;  1YLD B;  5JB7 A;  3BTG I;  1BTI A;  3AUI A;  3LDM A;  3TGK I;  1CO7 I;  1IRH A;  1FAN A;  1P2Q B;  3AUB A;  1KNT A;  5PTI A;  2ZJX A;  4WWY C;  1CA0 D;  4WXV C;  1FY8 I;  3AUG A;  2CA7 A;  2FI4 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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