3OFWA

Crystal structure of recombinant kunitz type serine protease inhibitor-1 from the carribean sea anemone stichodactyla helianthus
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
56
structure length
56
Chain Sequence
EASICSEPKKVGRCKGYFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHQCRAICR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Stichodactyla helianthus
molecule keywords Kunitz-type proteinase inhibitor SHPI-1
total genus 9
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 2010-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3ofwA00
1DTXA 1P2NB 1T7CB 3M7QB 5C67C 1FY8I 3L3TE 5JB5A 1TCPA 1TAWB 1B0CA 4PTIA 1EAWB 1TAPA 3FP6I 1KTHA 3BTFI 4Y10I 2LFKA 2KNTA 2ZVXA 1DTKA 1JV8A 2JOTA 1MTND 2RA3C 2ZJXA 1ZJDB 2FTMB 2FTLI 3LDMA 1Y62A 2UUYB 3UOUB 1TFXC 2KAII 1BRCI 1CO7I 1OA55 1G6XA 2LFLA 3AUIA 3GYMI 3LDJA 3FP7J 1BHCA 3CI7A 1D0DA 3FP8I 1P2OB 2IJOI 4WXVC 3P92E 3D65I 1CA0D 1F7ZI 1YC0I 1YLCB 2DDIA 1AAPA 1P2JI 2KCRA 1BTHP 2PTCI 5JB7A 3P95E 1PITA 3AUEA 2FI4I 3AUBA 1CBWD 3BTWI 1P2II 3TPII 2ODYE 3BTKI 3BTDI 1T8LB 4Y0YI 3UIRC 1JC6A 1UUAA 2HEXA 3BTMI 1DENA 3BTQI 3BTHI 1BPTA 7PTIA 4ISLB 1LD6A 2M99A 3AUGA 3LDIA 4NTWB 3WNYA 1BF0A 4U30W 3T62D 3TGII 1YKTB 1FAKI 4DTGK 3AUDA 1BTIA 4WWYC 1DEMA 3TGKI 1KNTA 6PTIA 1ADZA 4U32X 2J6DA 2DDJA 1T8OB 1KUNA 4ISNB 4BD9B 1BIKA 4TPII 5PTIA 5JB4A 3TGJI 1EJMB 1AALA 1QLQA 1P2MB 1F5RI 2FI5I 1IRHA 1FANA 2M01A 3OTJI 4ISOB 1P2QB 3AUHA 3BYBA 3BTTI 9PTIA 8PTIA 1T8NB 4Y11I 3BTEI 1K6UA 3L33E 3BTGI 1NAGA 4NTXB 1UUBA 2R9PE 1YLDB 1T8MB 1BPIA 2CA7A 1TPAI 4NTYB 1BRBI 1BZXI 1SHPA 1ZR0B 2TPII 4Y0ZI 3U1JE 2W8XA 1BUNB 3OFWA 1P2KI 1TOCR 5JB6A 2UUXA 1LD5A 2FI3I 1D0DB 3AUCA 4BQDA 1OA65 1KIGI 4BNRI 1BZ5A 1JV9A 4DG4C 2TGPI
chains in the Genus database with same CATH superfamily
1DTXA 1P2NB 1T7CB 3M7QB 5C67C 1FY8I 3L3TE 5JB5A 1TCPA 1TAWB 1B0CA 4PTIA 1EAWB 1TAPA 3FP6I 1KTHA 3BTFI 4Y10I 2LFKA 2KNTA 2ZVXA 1DTKA 1JV8A 2JOTA 1MTND 2RA3C 2ZJXA 1ZJDB 2FTMB 2FTLI 3LDMA 1Y62A 2UUYB 3UOUB 1TFXC 2KAII 1BRCI 1CO7I 1OA55 1G6XA 2LFLA 3AUIA 3GYMI 3LDJA 3FP7J 1BHCA 3CI7A 1D0DA 3FP8I 1P2OB 2IJOI 4WXVC 3P92E 3D65I 1CA0D 1F7ZI 1YC0I 1YLCB 2DDIA 1AAPA 1P2JI 2KCRA 1BTHP 2PTCI 5JB7A 3P95E 1PITA 3AUEA 2FI4I 3AUBA 1CBWD 3BTWI 1P2II 3TPII 2ODYE 3BTKI 3BTDI 1T8LB 4Y0YI 3UIRC 1JC6A 1UUAA 2HEXA 3BTMI 1DENA 3BTQI 3BTHI 1BPTA 7PTIA 4ISLB 1LD6A 2M99A 3AUGA 3LDIA 4NTWB 3WNYA 1BF0A 4U30W 3T62D 3TGII 1YKTB 1FAKI 4DTGK 3AUDA 1BTIA 4WWYC 1DEMA 3TGKI 1KNTA 6PTIA 1ADZA 4U32X 2J6DA 2DDJA 1T8OB 1KUNA 4ISNB 4BD9B 1BIKA 4TPII 5PTIA 5JB4A 3TGJI 1EJMB 1AALA 1QLQA 1P2MB 1F5RI 2FI5I 1IRHA 1FANA 2M01A 3OTJI 4ISOB 1P2QB 3AUHA 3BYBA 3BTTI 9PTIA 8PTIA 1T8NB 4Y11I 3BTEI 1K6UA 3L33E 3BTGI 1NAGA 4NTXB 1UUBA 2R9PE 1YLDB 1T8MB 1BPIA 2CA7A 1TPAI 4NTYB 1BRBI 1BZXI 1SHPA 1ZR0B 2TPII 4Y0ZI 3U1JE 2W8XA 1BUNB 3OFWA 1P2KI 1TOCR 5JB6A 2UUXA 1LD5A 2FI3I 1D0DB 3AUCA 4BQDA 1OA65 1KIGI 4BNRI 1BZ5A 1JV9A 4DG4C 2TGPI
chains in the Genus database with same CATH topology
1DTXA 1P2NB 1T7CB 3M7QB 5C67C 1FY8I 3L3TE 5JB5A 1TCPA 1TAWB 1B0CA 4PTIA 1EAWB 1TAPA 3FP6I 1KTHA 3BTFI 4Y10I 2LFKA 2KNTA 2ZVXA 1DTKA 1JV8A 2JOTA 1MTND 2RA3C 2ZJXA 1ZJDB 2FTMB 2FTLI 3LDMA 1Y62A 2UUYB 3UOUB 1TFXC 2KAII 1BRCI 1CO7I 1OA55 1G6XA 2LFLA 3AUIA 3GYMI 3LDJA 3FP7J 1BHCA 3CI7A 1D0DA 3FP8I 1P2OB 2IJOI 4WXVC 3P92E 3D65I 1CA0D 1F7ZI 1YC0I 1YLCB 2DDIA 1AAPA 1P2JI 2KCRA 1BTHP 2PTCI 5JB7A 3P95E 1PITA 3AUEA 2FI4I 3AUBA 1CBWD 3BTWI 1P2II 3TPII 2ODYE 3BTKI 3BTDI 1T8LB 4Y0YI 3UIRC 1JC6A 1UUAA 2HEXA 3BTMI 1DENA 3BTQI 3BTHI 1BPTA 7PTIA 4ISLB 1LD6A 2M99A 3AUGA 3LDIA 4NTWB 3WNYA 1BF0A 4U30W 3T62D 3TGII 1YKTB 1FAKI 4DTGK 3AUDA 1BTIA 4WWYC 1DEMA 3TGKI 1KNTA 6PTIA 1ADZA 4U32X 2J6DA 2DDJA 1T8OB 1KUNA 4ISNB 4BD9B 1BIKA 4TPII 5PTIA 5JB4A 3TGJI 1EJMB 1AALA 1QLQA 1P2MB 1F5RI 2FI5I 1IRHA 1FANA 2M01A 3OTJI 4ISOB 1P2QB 3AUHA 3BYBA 3BTTI 9PTIA 8PTIA 1T8NB 4Y11I 3BTEI 1K6UA 3L33E 3BTGI 1NAGA 4NTXB 1UUBA 2R9PE 1YLDB 1T8MB 1BPIA 2CA7A 1TPAI 4NTYB 1BRBI 1BZXI 1SHPA 1ZR0B 2TPII 4Y0ZI 3U1JE 2W8XA 1BUNB 3OFWA 1P2KI 1TOCR 5JB6A 2UUXA 1LD5A 2FI3I 1D0DB 3AUCA 4BQDA 1OA65 1KIGI 4BNRI 1BZ5A 1JV9A 4DG4C 2TGPI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DTX A;  1P2N B;  1T7C B;  3M7Q B;  5C67 C;  1FY8 I;  3L3T E;  5JB5 A;  1TCP A;  1TAW B;  1B0C A;  4PTI A;  1EAW B;  1TAP A;  3FP6 I;  1KTH A;  3BTF I;  4Y10 I;  2LFK A;  2KNT A;  2ZVX A;  1DTK A;  1JV8 A;  2JOT A;  1MTN D;  2RA3 C;  2ZJX A;  1ZJD B;  2FTM B;  2FTL I;  3LDM A;  1Y62 A;  2UUY B;  3UOU B;  1TFX C;  2KAI I;  1BRC I;  1CO7 I;  1OA5 5;  1G6X A;  2LFL A;  3AUI A;  3GYM I;  3LDJ A;  3FP7 J;  1BHC A;  3CI7 A;  1D0D A;  3FP8 I;  1P2O B;  2IJO I;  4WXV C;  3P92 E;  3D65 I;  1CA0 D;  1F7Z I;  1YC0 I;  1YLC B;  2DDI A;  1AAP A;  1P2J I;  2KCR A;  1BTH P;  2PTC I;  5JB7 A;  3P95 E;  1PIT A;  3AUE A;  2FI4 I;  3AUB A;  1CBW D;  3BTW I;  1P2I I;  3TPI I;  2ODY E;  3BTK I;  3BTD I;  1T8L B;  4Y0Y I;  3UIR C;  1JC6 A;  1UUA A;  2HEX A;  3BTM I;  1DEN A;  3BTQ I;  3BTH I;  1BPT A;  7PTI A;  4ISL B;  1LD6 A;  2M99 A;  3AUG A;  3LDI A;  4NTW B;  3WNY A;  1BF0 A;  4U30 W;  3T62 D;  3TGI I;  1YKT B;  1FAK I;  4DTG K;  3AUD A;  1BTI A;  4WWY C;  1DEM A;  3TGK I;  1KNT A;  6PTI A;  1ADZ A;  4U32 X;  2J6D A;  2DDJ A;  1T8O B;  1KUN A;  4ISN B;  4BD9 B;  1BIK A;  4TPI I;  5PTI A;  5JB4 A;  3TGJ I;  1EJM B;  1AAL A;  1QLQ A;  1P2M B;  1F5R I;  2FI5 I;  1IRH A;  1FAN A;  2M01 A;  3OTJ I;  4ISO B;  1P2Q B;  3AUH A;  3BYB A;  3BTT I;  9PTI A;  8PTI A;  1T8N B;  4Y11 I;  3BTE I;  1K6U A;  3L33 E;  3BTG I;  1NAG A;  4NTX B;  1UUB A;  2R9P E;  1YLD B;  1T8M B;  1BPI A;  2CA7 A;  1TPA I;  4NTY B;  1BRB I;  1BZX I;  1SHP A;  1ZR0 B;  2TPI I;  4Y0Z I;  3U1J E;  2W8X A;  1BUN B;  3OFW A;  1P2K I;  1TOC R;  5JB6 A;  2UUX A;  1LD5 A;  2FI3 I;  1D0D B;  3AUC A;  4BQD A;  1OA6 5;  1KIG I;  4BNR I;  1BZ5 A;  1JV9 A;  4DG4 C;  2TGP I; 
#chains in the Genus database with same CATH topology
 1DTX A;  1P2N B;  1T7C B;  3M7Q B;  5C67 C;  1FY8 I;  3L3T E;  5JB5 A;  1TCP A;  1TAW B;  1B0C A;  4PTI A;  1EAW B;  1TAP A;  3FP6 I;  1KTH A;  3BTF I;  4Y10 I;  2LFK A;  2KNT A;  2ZVX A;  1DTK A;  1JV8 A;  2JOT A;  1MTN D;  2RA3 C;  2ZJX A;  1ZJD B;  2FTM B;  2FTL I;  3LDM A;  1Y62 A;  2UUY B;  3UOU B;  1TFX C;  2KAI I;  1BRC I;  1CO7 I;  1OA5 5;  1G6X A;  2LFL A;  3AUI A;  3GYM I;  3LDJ A;  3FP7 J;  1BHC A;  3CI7 A;  1D0D A;  3FP8 I;  1P2O B;  2IJO I;  4WXV C;  3P92 E;  3D65 I;  1CA0 D;  1F7Z I;  1YC0 I;  1YLC B;  2DDI A;  1AAP A;  1P2J I;  2KCR A;  1BTH P;  2PTC I;  5JB7 A;  3P95 E;  1PIT A;  3AUE A;  2FI4 I;  3AUB A;  1CBW D;  3BTW I;  1P2I I;  3TPI I;  2ODY E;  3BTK I;  3BTD I;  1T8L B;  4Y0Y I;  3UIR C;  1JC6 A;  1UUA A;  2HEX A;  3BTM I;  1DEN A;  3BTQ I;  3BTH I;  1BPT A;  7PTI A;  4ISL B;  1LD6 A;  2M99 A;  3AUG A;  3LDI A;  4NTW B;  3WNY A;  1BF0 A;  4U30 W;  3T62 D;  3TGI I;  1YKT B;  1FAK I;  4DTG K;  3AUD A;  1BTI A;  4WWY C;  1DEM A;  3TGK I;  1KNT A;  6PTI A;  1ADZ A;  4U32 X;  2J6D A;  2DDJ A;  1T8O B;  1KUN A;  4ISN B;  4BD9 B;  1BIK A;  4TPI I;  5PTI A;  5JB4 A;  3TGJ I;  1EJM B;  1AAL A;  1QLQ A;  1P2M B;  1F5R I;  2FI5 I;  1IRH A;  1FAN A;  2M01 A;  3OTJ I;  4ISO B;  1P2Q B;  3AUH A;  3BYB A;  3BTT I;  9PTI A;  8PTI A;  1T8N B;  4Y11 I;  3BTE I;  1K6U A;  3L33 E;  3BTG I;  1NAG A;  4NTX B;  1UUB A;  2R9P E;  1YLD B;  1T8M B;  1BPI A;  2CA7 A;  1TPA I;  4NTY B;  1BRB I;  1BZX I;  1SHP A;  1ZR0 B;  2TPI I;  4Y0Z I;  3U1J E;  2W8X A;  1BUN B;  3OFW A;  1P2K I;  1TOC R;  5JB6 A;  2UUX A;  1LD5 A;  2FI3 I;  1D0D B;  3AUC A;  4BQD A;  1OA6 5;  1KIG I;  4BNR I;  1BZ5 A;  1JV9 A;  4DG4 C;  2TGP I; 
#chains in the Genus database with same CATH homology
 1DTX A;  1P2N B;  1T7C B;  3M7Q B;  5C67 C;  1FY8 I;  3L3T E;  5JB5 A;  1TCP A;  1TAW B;  1B0C A;  4PTI A;  1EAW B;  1TAP A;  3FP6 I;  1KTH A;  3BTF I;  4Y10 I;  2LFK A;  2KNT A;  2ZVX A;  1DTK A;  1JV8 A;  2JOT A;  1MTN D;  2RA3 C;  2ZJX A;  1ZJD B;  2FTM B;  2FTL I;  3LDM A;  1Y62 A;  2UUY B;  3UOU B;  1TFX C;  2KAI I;  1BRC I;  1CO7 I;  1OA5 5;  1G6X A;  2LFL A;  3AUI A;  3GYM I;  3LDJ A;  3FP7 J;  1BHC A;  3CI7 A;  1D0D A;  3FP8 I;  1P2O B;  2IJO I;  4WXV C;  3P92 E;  3D65 I;  1CA0 D;  1F7Z I;  1YC0 I;  1YLC B;  2DDI A;  1AAP A;  1P2J I;  2KCR A;  1BTH P;  2PTC I;  5JB7 A;  3P95 E;  1PIT A;  3AUE A;  2FI4 I;  3AUB A;  1CBW D;  3BTW I;  1P2I I;  3TPI I;  2ODY E;  3BTK I;  3BTD I;  1T8L B;  4Y0Y I;  3UIR C;  1JC6 A;  1UUA A;  2HEX A;  3BTM I;  1DEN A;  3BTQ I;  3BTH I;  1BPT A;  7PTI A;  4ISL B;  1LD6 A;  2M99 A;  3AUG A;  3LDI A;  4NTW B;  3WNY A;  1BF0 A;  4U30 W;  3T62 D;  3TGI I;  1YKT B;  1FAK I;  4DTG K;  3AUD A;  1BTI A;  4WWY C;  1DEM A;  3TGK I;  1KNT A;  6PTI A;  1ADZ A;  4U32 X;  2J6D A;  2DDJ A;  1T8O B;  1KUN A;  4ISN B;  4BD9 B;  1BIK A;  4TPI I;  5PTI A;  5JB4 A;  3TGJ I;  1EJM B;  1AAL A;  1QLQ A;  1P2M B;  1F5R I;  2FI5 I;  1IRH A;  1FAN A;  2M01 A;  3OTJ I;  4ISO B;  1P2Q B;  3AUH A;  3BYB A;  3BTT I;  9PTI A;  8PTI A;  1T8N B;  4Y11 I;  3BTE I;  1K6U A;  3L33 E;  3BTG I;  1NAG A;  4NTX B;  1UUB A;  2R9P E;  1YLD B;  1T8M B;  1BPI A;  2CA7 A;  1TPA I;  4NTY B;  1BRB I;  1BZX I;  1SHP A;  1ZR0 B;  2TPI I;  4Y0Z I;  3U1J E;  2W8X A;  1BUN B;  3OFW A;  1P2K I;  1TOC R;  5JB6 A;  2UUX A;  1LD5 A;  2FI3 I;  1D0D B;  3AUC A;  4BQD A;  1OA6 5;  1KIG I;  4BNR I;  1BZ5 A;  1JV9 A;  4DG4 C;  2TGP I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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