3PO2E

Arrested rna polymerase ii elongation complex
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of RNA polymerase II backtracking, arrest and reactivation.
pubmed doi rcsb
molecule tags Transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 63
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2010-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3po2E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3po2E02
4A93E 1I6HE 4A3DE 2NVXE 2Y0SH 3I4NE 5M3ME 3I4ME 3S2DE 3HOVE 3H3VF 3M4OE 1TWGE 3H0GE 4A3EE 2JA8E 2PMZH 3GTOE 3HOWE 3GTLE 2NVYE 3HOUE 4A3LE 2WB1H 2JA5E 3S1RE 2E2HE 3FKIE 4QIWH 4C2ME 5M5WE 3S1NE 3M3YE 2WAQH 1K83E 4A3BE 4Y52E 2JA6E 5IYCE 2R92E 4C3HE 3PO3E 4A3GE 4A3FE 1TWHE 5FLME 3S2HE 3HOXE 4A3KE 3HOZE 2NVTE 3PO2E 2B63E 3GTQE 3S1QE 5C4JE 2JA7E 2NVQE 3HOYE 5C4XE 5C3EE 5M5XE 4BY7E 5IP7E 4X6AE 1WCME 1SFOE 3S1ME 1EIKA 1TWCE 4A3JE 4Y7NE 3RZDE 3S15E 4C3IE 3GTPE 5C44E 3GTGE 4AYBH 4A3IE 1I50E 1I3QE 5IYBE 3GTME 4A3ME 3S17E 3CQZE 4BXXE 2R93E 2YU9E 1Y1VE 3HKZH 1Y1WE 4A3CE 2R7ZE 3K7AE 1TWAE 1DZFA 2VUME 1R9TE 4BY1E 4C3JE 2E2JE 4BBSE 3GTKE 3S14E 5IP9E 5M5YE 3GTJE 5M3FE 2E2IE 5IYDE 4BBRE 5FJ8E 3S16E 3RZOE 1TWFE
chains in the Genus database with same CATH superfamily
3CQZF 4A93E 1TWFF 1I6HE 4LJZE 1Y1VF 4A3DE 2NVXE 4MQ9E 2YU9F 4A93F 4ZH4E 4A3DF 2NVXF 2Y0SH 3I4NE 2R7ZF 5M3ME 3I4ME 3S2DE 3K7AF 2O5IE 3I4NF 3HOVE 5M3MF 3I4MF 3S2DF 3H3VF 3M4OE 1TWGE 1R9TF 3HOVF 3H0GE 3M4OF 1TWGF 5D4CE 3H0GF 4A3EE 4C3JF 2JA8E 4YFNE 2KRXA 2E2JF 4A3EF 2PMZH 3GTOE 3HOWE 3GTLE 2NVYE 5M5YF 3GTJF 3GTOF 3EQLE 3GTLF 5M3FF 3HOUE 4A3LE 1YNNK 2WB1H 5IYDF 2JA5E 2CW0E 4XLNE 4OINE 4A3LF 3S1RE 4OIOE 2E2HE 3FKIE 3S1RF 4QIWH 2E2HF 3FKIF 5BYHE 4Q4ZE 4G7ZE 2PMZK 4YFXE 1I6HF 4C2ME 4C2MF 4G7OE 5M5WE 4KMUE 3S1NE 3M3YE 4MEYE 2WAQH 1K83E 4A3BE 5M5WF 4Y52E 2JA6E 5E18E 3M3YF 3S1NF 1K83F 4YG2E 4A3BF 2JA6F 5IYCE 2R92E 4C3HE 2R92F 4OIRE 4JK1E 4C3HF 3DXJE 3PO3E 4A3GE 4A3FE 1TWHE 2A6HE 5FLME 4XLPE 2JA8F 5E17E 3PO3F 4A3GF 3S2HE 1TWHF 4YFKE 5FLMF 3HOXE 4A3KE 3HOZE 2NVTE 3PO2E 3HOWF 2B63E 2NVYF 3S2HF 3HOXF 4A3KF 4GZYE 3GTQE 2NVTF 2WAQK 4G7HE 3S1QE 2PPBE 3HOUF 1IW7E 3PO2F 3GTQF 4Q5SE 5C4JE 5IPLE 3S1QF 2JA7E 2JA5F 2NVQE 5C4JF 3HOYE 1I6VE 2JA7F 5TMCE 2NVQF 5C4XE 3HOYF 5C3EE 3WODE 5M5XE 5C3EF 4BY7E 5M5XF 5IP7E 4X6AE 1WCME 1SFOE 3S1ME 5IP7F 4X6AF 1WCMF 1EIKA 4XSZE 1TWCE 4A3JE 4Y7NE 3RZDE 3S1MF 1TWCF 4Y52F 4A3JF 3S15E 3RZDF 4C3IE 3GTPE 5IYCF 3S15F 2A68E 4QIWK 5C44E 3GTPF 3GTGE 4AYBH 2O5JE 4A3IE 1I50E 1I3QE 5IYBE 3GTME 1QKLA 4A3ME 4A3IF 1I50F 1I3QF 3S17E 5IYBF 4A3FF 3GTMF 4OIQE 4KN7E 3S17F 4LK1E 3CQZE 4OIPE 3HOZF 4BXXE 2R93E 2Y0SI 2B63F 2YU9E 1Y1VE 4BXXF 4LK0E 2R93F 3HKZH 1Y1WE 4BBSF 4A3CE 4XSXE 1Y1WF 4A3CF 2R7ZE 2BE5E 3K7AE 1TWAE 1DZFA 2VUME 4AYBK 5C4XF 1HQME 2VUMF 1TWAF 1R9TE 3H3VG 4BY1E 4BY1F 4BY7F 4C3JE 2E2JE 4MEXE 1SFOF 1ZYRE 4BBSE 3GTKE 1SMYE 3S14E 3HKZK 2WB1I 5TMFE 5IP9E 5M5YE 3GTJE 4Y7NF 3GTKF 3S14F 2A6EE 5M3FE 5IP9F 2E2IE 4KN4E 4C3IF 5IYDE 2E2IF 5C44F 5D4DE 1YNJK 4BBRE 3GTGF 5FJ8E 5D4EE 2A69E 3S16E 4BBRF 4LLGE 5FJ8F 4A3MF 3RZOE 3S16F 1TWFE 3RZOF
chains in the Genus database with same CATH topology
4A93E 1I6HE 4A3DE 2NVXE 2Y0SH 3I4NE 5M3ME 3I4ME 3S2DE 3HOVE 3H3VF 3M4OE 1TWGE 3H0GE 4A3EE 2JA8E 2PMZH 3GTOE 3HOWE 3GTLE 2NVYE 3HOUE 4A3LE 2WB1H 2JA5E 3S1RE 2E2HE 3FKIE 4QIWH 4C2ME 5M5WE 3S1NE 3M3YE 2WAQH 1K83E 4A3BE 4Y52E 2JA6E 5IYCE 2R92E 4C3HE 3PO3E 4A3GE 4A3FE 1TWHE 5FLME 3S2HE 3HOXE 4A3KE 3HOZE 2NVTE 3PO2E 2B63E 3GTQE 3S1QE 5C4JE 2JA7E 2NVQE 3HOYE 5C4XE 5C3EE 5M5XE 4BY7E 5IP7E 4X6AE 1WCME 1SFOE 3S1ME 1EIKA 1TWCE 4A3JE 4Y7NE 3RZDE 3S15E 4C3IE 3GTPE 5C44E 3GTGE 4AYBH 4A3IE 1I50E 1I3QE 5IYBE 3GTME 4A3ME 3S17E 3CQZE 4BXXE 2R93E 2YU9E 1Y1VE 3HKZH 1Y1WE 4A3CE 2R7ZE 3K7AE 1TWAE 1DZFA 2VUME 1R9TE 4BY1E 4C3JE 2E2JE 4BBSE 3GTKE 3S14E 5IP9E 5M5YE 3GTJE 5M3FE 2E2IE 5IYDE 4BBRE 5FJ8E 3S16E 3RZOE 1TWFE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A93 E;  1I6H E;  4A3D E;  2NVX E;  2Y0S H;  3I4N E;  5M3M E;  3I4M E;  3S2D E;  3HOV E;  3H3V F;  3M4O E;  1TWG E;  3H0G E;  4A3E E;  2JA8 E;  2PMZ H;  3GTO E;  3HOW E;  3GTL E;  2NVY E;  3HOU E;  4A3L E;  2WB1 H;  2JA5 E;  3S1R E;  2E2H E;  3FKI E;  4QIW H;  4C2M E;  5M5W E;  3S1N E;  3M3Y E;  2WAQ H;  1K83 E;  4A3B E;  4Y52 E;  2JA6 E;  5IYC E;  2R92 E;  4C3H E;  3PO3 E;  4A3G E;  4A3F E;  1TWH E;  5FLM E;  3S2H E;  3HOX E;  4A3K E;  3HOZ E;  2NVT E;  3PO2 E;  2B63 E;  3GTQ E;  3S1Q E;  5C4J E;  2JA7 E;  2NVQ E;  3HOY E;  5C4X E;  5C3E E;  5M5X E;  4BY7 E;  5IP7 E;  4X6A E;  1WCM E;  1SFO E;  3S1M E;  1EIK A;  1TWC E;  4A3J E;  4Y7N E;  3RZD E;  3S15 E;  4C3I E;  3GTP E;  5C44 E;  3GTG E;  4AYB H;  4A3I E;  1I50 E;  1I3Q E;  5IYB E;  3GTM E;  4A3M E;  3S17 E;  3CQZ E;  4BXX E;  2R93 E;  2YU9 E;  1Y1V E;  3HKZ H;  1Y1W E;  4A3C E;  2R7Z E;  3K7A E;  1TWA E;  1DZF A;  2VUM E;  1R9T E;  4BY1 E;  4C3J E;  2E2J E;  4BBS E;  3GTK E;  3S14 E;  5IP9 E;  5M5Y E;  3GTJ E;  5M3F E;  2E2I E;  5IYD E;  4BBR E;  5FJ8 E;  3S16 E;  3RZO E;  1TWF E; 
#chains in the Genus database with same CATH topology
 3CQZ F;  4A93 E;  1TWF F;  1I6H E;  4LJZ E;  1Y1V F;  4A3D E;  2NVX E;  4MQ9 E;  2YU9 F;  4A93 F;  4ZH4 E;  4A3D F;  2NVX F;  2Y0S H;  3I4N E;  2R7Z F;  5M3M E;  3I4M E;  3S2D E;  3K7A F;  2O5I E;  3I4N F;  3HOV E;  5M3M F;  3I4M F;  3S2D F;  3H3V F;  3M4O E;  1TWG E;  1R9T F;  3HOV F;  3H0G E;  3M4O F;  1TWG F;  5D4C E;  3H0G F;  4A3E E;  4C3J F;  2JA8 E;  4YFN E;  2KRX A;  2E2J F;  4A3E F;  2PMZ H;  3GTO E;  3HOW E;  3GTL E;  2NVY E;  5M5Y F;  3GTJ F;  3GTO F;  3EQL E;  3GTL F;  5M3F F;  3HOU E;  4A3L E;  1YNN K;  2WB1 H;  5IYD F;  2JA5 E;  2CW0 E;  4XLN E;  4OIN E;  4A3L F;  3S1R E;  4OIO E;  2E2H E;  3FKI E;  3S1R F;  4QIW H;  2E2H F;  3FKI F;  5BYH E;  4Q4Z E;  4G7Z E;  2PMZ K;  4YFX E;  1I6H F;  4C2M E;  4C2M F;  4G7O E;  5M5W E;  4KMU E;  3S1N E;  3M3Y E;  4MEY E;  2WAQ H;  1K83 E;  4A3B E;  5M5W F;  4Y52 E;  2JA6 E;  5E18 E;  3M3Y F;  3S1N F;  1K83 F;  4YG2 E;  4A3B F;  2JA6 F;  5IYC E;  2R92 E;  4C3H E;  2R92 F;  4OIR E;  4JK1 E;  4C3H F;  3DXJ E;  3PO3 E;  4A3G E;  4A3F E;  1TWH E;  2A6H E;  5FLM E;  4XLP E;  2JA8 F;  5E17 E;  3PO3 F;  4A3G F;  3S2H E;  1TWH F;  4YFK E;  5FLM F;  3HOX E;  4A3K E;  3HOZ E;  2NVT E;  3PO2 E;  3HOW F;  2B63 E;  2NVY F;  3S2H F;  3HOX F;  4A3K F;  4GZY E;  3GTQ E;  2NVT F;  2WAQ K;  4G7H E;  3S1Q E;  2PPB E;  3HOU F;  1IW7 E;  3PO2 F;  3GTQ F;  4Q5S E;  5C4J E;  5IPL E;  3S1Q F;  2JA7 E;  2JA5 F;  2NVQ E;  5C4J F;  3HOY E;  1I6V E;  2JA7 F;  5TMC E;  2NVQ F;  5C4X E;  3HOY F;  5C3E E;  3WOD E;  5M5X E;  5C3E F;  4BY7 E;  5M5X F;  5IP7 E;  4X6A E;  1WCM E;  1SFO E;  3S1M E;  5IP7 F;  4X6A F;  1WCM F;  1EIK A;  4XSZ E;  1TWC E;  4A3J E;  4Y7N E;  3RZD E;  3S1M F;  1TWC F;  4Y52 F;  4A3J F;  3S15 E;  3RZD F;  4C3I E;  3GTP E;  5IYC F;  3S15 F;  2A68 E;  4QIW K;  5C44 E;  3GTP F;  3GTG E;  4AYB H;  2O5J E;  4A3I E;  1I50 E;  1I3Q E;  5IYB E;  3GTM E;  1QKL A;  4A3M E;  4A3I F;  1I50 F;  1I3Q F;  3S17 E;  5IYB F;  4A3F F;  3GTM F;  4OIQ E;  4KN7 E;  3S17 F;  4LK1 E;  3CQZ E;  4OIP E;  3HOZ F;  4BXX E;  2R93 E;  2Y0S I;  2B63 F;  2YU9 E;  1Y1V E;  4BXX F;  4LK0 E;  2R93 F;  3HKZ H;  1Y1W E;  4BBS F;  4A3C E;  4XSX E;  1Y1W F;  4A3C F;  2R7Z E;  2BE5 E;  3K7A E;  1TWA E;  1DZF A;  2VUM E;  4AYB K;  5C4X F;  1HQM E;  2VUM F;  1TWA F;  1R9T E;  3H3V G;  4BY1 E;  4BY1 F;  4BY7 F;  4C3J E;  2E2J E;  4MEX E;  1SFO F;  1ZYR E;  4BBS E;  3GTK E;  1SMY E;  3S14 E;  3HKZ K;  2WB1 I;  5TMF E;  5IP9 E;  5M5Y E;  3GTJ E;  4Y7N F;  3GTK F;  3S14 F;  2A6E E;  5M3F E;  5IP9 F;  2E2I E;  4KN4 E;  4C3I F;  5IYD E;  2E2I F;  5C44 F;  5D4D E;  1YNJ K;  4BBR E;  3GTG F;  5FJ8 E;  5D4E E;  2A69 E;  3S16 E;  4BBR F;  4LLG E;  5FJ8 F;  4A3M F;  3RZO E;  3S16 F;  1TWF E;  3RZO F; 
#chains in the Genus database with same CATH homology
 4A93 E;  1I6H E;  4A3D E;  2NVX E;  2Y0S H;  3I4N E;  5M3M E;  3I4M E;  3S2D E;  3HOV E;  3H3V F;  3M4O E;  1TWG E;  3H0G E;  4A3E E;  2JA8 E;  2PMZ H;  3GTO E;  3HOW E;  3GTL E;  2NVY E;  3HOU E;  4A3L E;  2WB1 H;  2JA5 E;  3S1R E;  2E2H E;  3FKI E;  4QIW H;  4C2M E;  5M5W E;  3S1N E;  3M3Y E;  2WAQ H;  1K83 E;  4A3B E;  4Y52 E;  2JA6 E;  5IYC E;  2R92 E;  4C3H E;  3PO3 E;  4A3G E;  4A3F E;  1TWH E;  5FLM E;  3S2H E;  3HOX E;  4A3K E;  3HOZ E;  2NVT E;  3PO2 E;  2B63 E;  3GTQ E;  3S1Q E;  5C4J E;  2JA7 E;  2NVQ E;  3HOY E;  5C4X E;  5C3E E;  5M5X E;  4BY7 E;  5IP7 E;  4X6A E;  1WCM E;  1SFO E;  3S1M E;  1EIK A;  1TWC E;  4A3J E;  4Y7N E;  3RZD E;  3S15 E;  4C3I E;  3GTP E;  5C44 E;  3GTG E;  4AYB H;  4A3I E;  1I50 E;  1I3Q E;  5IYB E;  3GTM E;  4A3M E;  3S17 E;  3CQZ E;  4BXX E;  2R93 E;  2YU9 E;  1Y1V E;  3HKZ H;  1Y1W E;  4A3C E;  2R7Z E;  3K7A E;  1TWA E;  1DZF A;  2VUM E;  1R9T E;  4BY1 E;  4C3J E;  2E2J E;  4BBS E;  3GTK E;  3S14 E;  5IP9 E;  5M5Y E;  3GTJ E;  5M3F E;  2E2I E;  5IYD E;  4BBR E;  5FJ8 E;  3S16 E;  3RZO E;  1TWF E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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