3PO3E

Arrested rna polymerase ii reactivation intermediate
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of RNA polymerase II backtracking, arrest and reactivation.
pubmed doi rcsb
molecule tags Transferase/dna/rna
source organism Saccharomyces cerevisiae
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 73
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2010-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3po3E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3po3E02
4BXXE 2VUME 5IP9E 3S1NE 3PO2E 4A3EE 3M4OE 4BBRE 2E2JE 3GTQE 3GTGE 4BY1E 3HOYE 2Y0SH 4AYBH 1TWHE 2YU9E 1I50E 3HOZE 1R9TE 3GTPE 4QIWH 3S1QE 3HOXE 2E2IE 3GTJE 3FKIE 1SFOE 5IYDE 2JA5E 3S15E 4X6AE 3H3VF 5FJ8E 2NVYE 5M5XE 1Y1WE 3HKZH 4C2ME 4BBSE 5IP7E 4Y7NE 3GTME 2R93E 1K83E 2R7ZE 4A3LE 3S16E 3CQZE 3S17E 3HOWE 3HOVE 4A3BE 1I3QE 2E2HE 5M5YE 3S2DE 3I4NE 3H0GE 5C4JE 2NVTE 2NVXE 5C44E 1WCME 3S1RE 2JA7E 4A3GE 5C3EE 3S2HE 4A93E 1TWFE 4BY7E 4A3IE 4Y52E 2B63E 3RZOE 1Y1VE 3K7AE 5C4XE 3I4ME 5IYCE 2JA8E 4A3DE 3GTOE 2JA6E 5FLME 3M3YE 2NVQE 5M5WE 3PO3E 5M3FE 1I6HE 2WB1H 2WAQH 4A3CE 3HOUE 3RZDE 1TWCE 4A3FE 4C3JE 4A3KE 1TWGE 3GTLE 3S14E 4C3IE 4C3HE 3S1ME 4A3JE 5M3ME 2PMZH 3GTKE 2R92E 1TWAE 4A3ME 5IYBE 1DZFA 1EIKA
chains in the Genus database with same CATH superfamily
4G7ZE 2R92F 1TWAF 4A3MF 4BXXE 2VUME 5IYBF 4MEYE 5IP9E 3S1NE 5E18E 3PO2E 4A3EE 3M4OE 5TMCE 4BBRE 1QKLA 2A68E 4BXXF 2E2JE 4JK1E 2VUMF 4Q4ZE 3GTQE 5IP9F 3S1NF 3GTGE 3M4OF 4BY1E 3HOYE 4A3EF 3PO2F 2Y0SH 4AYBH 4BBRF 1TWHE 5TMFE 2YU9E 1I50E 2E2JF 3HOZE 1R9TE 3GTPE 3WODE 3GTGF 4QIWH 3S1QE 3GTQF 4BY1F 3HOYF 4QIWK 5D4EE 2NVTF 1TWHF 3HOXE 2E2IE 2YU9F 1I50F 1SMYE 3HOZF 3GTJE 1R9TF 3GTPF 1IW7E 4OIQE 3S1QF 4YFNE 2O5JE 3HOXF 2E2IF 3FKIE 1SFOE 5IYDE 3GTJF 4G7HE 5D4DE 3EQLE 2JA5E 2Y0SI 3S15E 2O5IE 3FKIF 1SFOF 4G7OE 4X6AE 4MQ9E 5IYDF 4GZYE 3H3VF 4KMUE 5FJ8E 2JA5F 3S15F 2NVYE 5M5XE 4XLPE 4MEXE 1Y1WE 4X6AF 1YNNK 3GTKF 3HKZH 5FJ8F 4YFXE 3HKZK 4C2ME 2NVYF 5M5XF 5IPLE 4BBSE 5IP7E 4Y7NE 1Y1WF 4OINE 1I6VE 3GTME 1YNJK 4LK1E 2R93E 4ZH4E 1K83E 2R7ZE 4C2MF 2R93F 4A3LE 3S16E 3CQZE 3S17E 4LJZE 4BBSF 5IP7F 4Y7NF 3HOWE 3HOVE 4LLGE 4A3BE 1I3QE 3GTMF 2E2HE 5M5YE 3S2DE 3I4NE 1K83F 3H0GE 5C4JE 2NVTE 4YG2E 2R7ZF 4A3LF 3S16F 2NVXE 3CQZF 3S17F 5C44E 2PPBE 1WCME 3S1RE 2JA7E 4A3GE 4XSZE 3HOVF 3HOWF 1I3QF 4A3BF 5C3EE 4YFKE 4KN4E 5M5YF 2E2HF 3I4NF 3H0GF 5C4JF 3S2HE 4A93E 4XLNE 1TWFE 5D4CE 2NVXF 4BY7E 4A3IE 4Y52E 2B63E 5C44F 4OIOE 1WCMF 3S1RF 2JA7F 4A3GF 3RZOE 1Y1VE 5C3EF 3K7AE 5C4XE 3S2HF 4A93F 3I4ME 1TWFF 5IYCE 2JA8E 4BY7F 4Y52F 4A3IF 4A3DE 3DXJE 3GTOE 2PMZK 3RZOF 1HQME 1Y1VF 3K7AF 5C4XF 2JA6E 3I4MF 5FLME 3M3YE 2NVQE 2BE5E 5IYCF 2JA8F 4A3DF 5M5WE 4LK0E 3GTOF 3PO3E 5M3FE 1I6HE 2JA6F 2WB1H 2WAQH 5FLMF 4A3CE 2NVQF 3M3YF 2WAQK 5M5WF 3HOUE 5M3FF 3RZDE 1I6HF 1TWCE 3PO3F 4A3FE 4XSXE 4C3JE 4Q5SE 4A3KE 4A3CF 1TWGE 4OIPE 3GTLE 3HOUF 3S14E 3RZDF 3S2DF 1TWCF 4OIRE 4A3FF 4AYBK 4C3JF 3H3VG 4A3KF 1TWGF 4C3IE 2CW0E 5BYHE 2A6EE 1ZYRE 3GTLF 3S14F 2A69E 4C3HE 3S1ME 4A3JE 2A6HE 5M3ME 2PMZH 2B63F 2WB1I 5E17E 3GTKE 2KRXA 4C3IF 2R92E 1TWAE 4A3ME 4C3HF 3S1MF 4A3JF 5IYBE 5M3MF 4KN7E 1DZFA 1EIKA
chains in the Genus database with same CATH topology
4BXXE 2VUME 5IP9E 3S1NE 3PO2E 4A3EE 3M4OE 4BBRE 2E2JE 3GTQE 3GTGE 4BY1E 3HOYE 2Y0SH 4AYBH 1TWHE 2YU9E 1I50E 3HOZE 1R9TE 3GTPE 4QIWH 3S1QE 3HOXE 2E2IE 3GTJE 3FKIE 1SFOE 5IYDE 2JA5E 3S15E 4X6AE 3H3VF 5FJ8E 2NVYE 5M5XE 1Y1WE 3HKZH 4C2ME 4BBSE 5IP7E 4Y7NE 3GTME 2R93E 1K83E 2R7ZE 4A3LE 3S16E 3CQZE 3S17E 3HOWE 3HOVE 4A3BE 1I3QE 2E2HE 5M5YE 3S2DE 3I4NE 3H0GE 5C4JE 2NVTE 2NVXE 5C44E 1WCME 3S1RE 2JA7E 4A3GE 5C3EE 3S2HE 4A93E 1TWFE 4BY7E 4A3IE 4Y52E 2B63E 3RZOE 1Y1VE 3K7AE 5C4XE 3I4ME 5IYCE 2JA8E 4A3DE 3GTOE 2JA6E 5FLME 3M3YE 2NVQE 5M5WE 3PO3E 5M3FE 1I6HE 2WB1H 2WAQH 4A3CE 3HOUE 3RZDE 1TWCE 4A3FE 4C3JE 4A3KE 1TWGE 3GTLE 3S14E 4C3IE 4C3HE 3S1ME 4A3JE 5M3ME 2PMZH 3GTKE 2R92E 1TWAE 4A3ME 5IYBE 1DZFA 1EIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BXX E;  2VUM E;  5IP9 E;  3S1N E;  3PO2 E;  4A3E E;  3M4O E;  4BBR E;  2E2J E;  3GTQ E;  3GTG E;  4BY1 E;  3HOY E;  2Y0S H;  4AYB H;  1TWH E;  2YU9 E;  1I50 E;  3HOZ E;  1R9T E;  3GTP E;  4QIW H;  3S1Q E;  3HOX E;  2E2I E;  3GTJ E;  3FKI E;  1SFO E;  5IYD E;  2JA5 E;  3S15 E;  4X6A E;  3H3V F;  5FJ8 E;  2NVY E;  5M5X E;  1Y1W E;  3HKZ H;  4C2M E;  4BBS E;  5IP7 E;  4Y7N E;  3GTM E;  2R93 E;  1K83 E;  2R7Z E;  4A3L E;  3S16 E;  3CQZ E;  3S17 E;  3HOW E;  3HOV E;  4A3B E;  1I3Q E;  2E2H E;  5M5Y E;  3S2D E;  3I4N E;  3H0G E;  5C4J E;  2NVT E;  2NVX E;  5C44 E;  1WCM E;  3S1R E;  2JA7 E;  4A3G E;  5C3E E;  3S2H E;  4A93 E;  1TWF E;  4BY7 E;  4A3I E;  4Y52 E;  2B63 E;  3RZO E;  1Y1V E;  3K7A E;  5C4X E;  3I4M E;  5IYC E;  2JA8 E;  4A3D E;  3GTO E;  2JA6 E;  5FLM E;  3M3Y E;  2NVQ E;  5M5W E;  3PO3 E;  5M3F E;  1I6H E;  2WB1 H;  2WAQ H;  4A3C E;  3HOU E;  3RZD E;  1TWC E;  4A3F E;  4C3J E;  4A3K E;  1TWG E;  3GTL E;  3S14 E;  4C3I E;  4C3H E;  3S1M E;  4A3J E;  5M3M E;  2PMZ H;  3GTK E;  2R92 E;  1TWA E;  4A3M E;  5IYB E;  1DZF A;  1EIK A; 
#chains in the Genus database with same CATH topology
 4G7Z E;  2R92 F;  1TWA F;  4A3M F;  4BXX E;  2VUM E;  5IYB F;  4MEY E;  5IP9 E;  3S1N E;  5E18 E;  3PO2 E;  4A3E E;  3M4O E;  5TMC E;  4BBR E;  1QKL A;  2A68 E;  4BXX F;  2E2J E;  4JK1 E;  2VUM F;  4Q4Z E;  3GTQ E;  5IP9 F;  3S1N F;  3GTG E;  3M4O F;  4BY1 E;  3HOY E;  4A3E F;  3PO2 F;  2Y0S H;  4AYB H;  4BBR F;  1TWH E;  5TMF E;  2YU9 E;  1I50 E;  2E2J F;  3HOZ E;  1R9T E;  3GTP E;  3WOD E;  3GTG F;  4QIW H;  3S1Q E;  3GTQ F;  4BY1 F;  3HOY F;  4QIW K;  5D4E E;  2NVT F;  1TWH F;  3HOX E;  2E2I E;  2YU9 F;  1I50 F;  1SMY E;  3HOZ F;  3GTJ E;  1R9T F;  3GTP F;  1IW7 E;  4OIQ E;  3S1Q F;  4YFN E;  2O5J E;  3HOX F;  2E2I F;  3FKI E;  1SFO E;  5IYD E;  3GTJ F;  4G7H E;  5D4D E;  3EQL E;  2JA5 E;  2Y0S I;  3S15 E;  2O5I E;  3FKI F;  1SFO F;  4G7O E;  4X6A E;  4MQ9 E;  5IYD F;  4GZY E;  3H3V F;  4KMU E;  5FJ8 E;  2JA5 F;  3S15 F;  2NVY E;  5M5X E;  4XLP E;  4MEX E;  1Y1W E;  4X6A F;  1YNN K;  3GTK F;  3HKZ H;  5FJ8 F;  4YFX E;  3HKZ K;  4C2M E;  2NVY F;  5M5X F;  5IPL E;  4BBS E;  5IP7 E;  4Y7N E;  1Y1W F;  4OIN E;  1I6V E;  3GTM E;  1YNJ K;  4LK1 E;  2R93 E;  4ZH4 E;  1K83 E;  2R7Z E;  4C2M F;  2R93 F;  4A3L E;  3S16 E;  3CQZ E;  3S17 E;  4LJZ E;  4BBS F;  5IP7 F;  4Y7N F;  3HOW E;  3HOV E;  4LLG E;  4A3B E;  1I3Q E;  3GTM F;  2E2H E;  5M5Y E;  3S2D E;  3I4N E;  1K83 F;  3H0G E;  5C4J E;  2NVT E;  4YG2 E;  2R7Z F;  4A3L F;  3S16 F;  2NVX E;  3CQZ F;  3S17 F;  5C44 E;  2PPB E;  1WCM E;  3S1R E;  2JA7 E;  4A3G E;  4XSZ E;  3HOV F;  3HOW F;  1I3Q F;  4A3B F;  5C3E E;  4YFK E;  4KN4 E;  5M5Y F;  2E2H F;  3I4N F;  3H0G F;  5C4J F;  3S2H E;  4A93 E;  4XLN E;  1TWF E;  5D4C E;  2NVX F;  4BY7 E;  4A3I E;  4Y52 E;  2B63 E;  5C44 F;  4OIO E;  1WCM F;  3S1R F;  2JA7 F;  4A3G F;  3RZO E;  1Y1V E;  5C3E F;  3K7A E;  5C4X E;  3S2H F;  4A93 F;  3I4M E;  1TWF F;  5IYC E;  2JA8 E;  4BY7 F;  4Y52 F;  4A3I F;  4A3D E;  3DXJ E;  3GTO E;  2PMZ K;  3RZO F;  1HQM E;  1Y1V F;  3K7A F;  5C4X F;  2JA6 E;  3I4M F;  5FLM E;  3M3Y E;  2NVQ E;  2BE5 E;  5IYC F;  2JA8 F;  4A3D F;  5M5W E;  4LK0 E;  3GTO F;  3PO3 E;  5M3F E;  1I6H E;  2JA6 F;  2WB1 H;  2WAQ H;  5FLM F;  4A3C E;  2NVQ F;  3M3Y F;  2WAQ K;  5M5W F;  3HOU E;  5M3F F;  3RZD E;  1I6H F;  1TWC E;  3PO3 F;  4A3F E;  4XSX E;  4C3J E;  4Q5S E;  4A3K E;  4A3C F;  1TWG E;  4OIP E;  3GTL E;  3HOU F;  3S14 E;  3RZD F;  3S2D F;  1TWC F;  4OIR E;  4A3F F;  4AYB K;  4C3J F;  3H3V G;  4A3K F;  1TWG F;  4C3I E;  2CW0 E;  5BYH E;  2A6E E;  1ZYR E;  3GTL F;  3S14 F;  2A69 E;  4C3H E;  3S1M E;  4A3J E;  2A6H E;  5M3M E;  2PMZ H;  2B63 F;  2WB1 I;  5E17 E;  3GTK E;  2KRX A;  4C3I F;  2R92 E;  1TWA E;  4A3M E;  4C3H F;  3S1M F;  4A3J F;  5IYB E;  5M3M F;  4KN7 E;  1DZF A;  1EIK A; 
#chains in the Genus database with same CATH homology
 4BXX E;  2VUM E;  5IP9 E;  3S1N E;  3PO2 E;  4A3E E;  3M4O E;  4BBR E;  2E2J E;  3GTQ E;  3GTG E;  4BY1 E;  3HOY E;  2Y0S H;  4AYB H;  1TWH E;  2YU9 E;  1I50 E;  3HOZ E;  1R9T E;  3GTP E;  4QIW H;  3S1Q E;  3HOX E;  2E2I E;  3GTJ E;  3FKI E;  1SFO E;  5IYD E;  2JA5 E;  3S15 E;  4X6A E;  3H3V F;  5FJ8 E;  2NVY E;  5M5X E;  1Y1W E;  3HKZ H;  4C2M E;  4BBS E;  5IP7 E;  4Y7N E;  3GTM E;  2R93 E;  1K83 E;  2R7Z E;  4A3L E;  3S16 E;  3CQZ E;  3S17 E;  3HOW E;  3HOV E;  4A3B E;  1I3Q E;  2E2H E;  5M5Y E;  3S2D E;  3I4N E;  3H0G E;  5C4J E;  2NVT E;  2NVX E;  5C44 E;  1WCM E;  3S1R E;  2JA7 E;  4A3G E;  5C3E E;  3S2H E;  4A93 E;  1TWF E;  4BY7 E;  4A3I E;  4Y52 E;  2B63 E;  3RZO E;  1Y1V E;  3K7A E;  5C4X E;  3I4M E;  5IYC E;  2JA8 E;  4A3D E;  3GTO E;  2JA6 E;  5FLM E;  3M3Y E;  2NVQ E;  5M5W E;  3PO3 E;  5M3F E;  1I6H E;  2WB1 H;  2WAQ H;  4A3C E;  3HOU E;  3RZD E;  1TWC E;  4A3F E;  4C3J E;  4A3K E;  1TWG E;  3GTL E;  3S14 E;  4C3I E;  4C3H E;  3S1M E;  4A3J E;  5M3M E;  2PMZ H;  3GTK E;  2R92 E;  1TWA E;  4A3M E;  5IYB E;  1DZF A;  1EIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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