3RD7A

Crystal structure of acyl-coa thioesterase from mycobacterium avium
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
281
structure length
275
Chain Sequence
MISTLEDVLSLLDLQQIDDAAFVGTQPDTPNHHIIGSQVAAQALMAAGRTTPGRLAHSMHMYFLRRGDARQPIQYDVTPLRDGGTISSRRVTASQSGVVLFEALASFTIIADDVDWQQRMPDVAGPSAVHGLEDLLAPYAEEFQRPFTMRYLDAPPRVALDLSDPPPPRLRIWLRANGEVTDDPLVNSCVVAYLSALTLLECVMTTMRTTPVGPRLSALVDHTIWFHRAADFTDWLLFDQFSPSIVGRRGLATGTLYNRSGELVCIATQEGYFAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium avium
molecule keywords Acyl-CoA thioesterase
total genus 77
structure length 275
sequence length 281
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13622 4HBT_3 Thioesterase-like superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.90 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 3rd7A00
4R4UA 3RD7A 4R9ZA 3CJYA 4QFWA 3BBJA 3RQBA 3U0AA
chains in the Genus database with same CATH superfamily
1Q4UA 4QDBA 5E1VA 5T07A 4A0YA 4YBVA 3DP1A 4I83A 3LWGA 4QD8A 2HLJA 3NWZA 3LMBA 2EGJA 4ZRBA 2QQPA 3KX8A 4RLUA 1Z6BA 2C2IA 3R87A 1PN4A 3CJYA 2XEMA 3HM0A 4H4GA 1Y7UA 4RLUB 4U3VA 4A12A 2FS2A 4MOBA 2PRXA 3S6PA 3KG7A 2OKHA 2O5UA 2OWNA 3F1TA 3P2QA 3DOYA 4MTUA 4WNBA 2NUJA 4A0XA 2QWZA 5HZ4A 5EGKA 5BUWA 3R32A 2GVHA 3AZAA 2H4UA 3R36A 4QDAA 5F6RA 3BBJA 3KUVA 3KW1A 3R3AA 3DKZA 4AE8A 5DIOA 4A0ZA 4RLTA 4KC5A 3R3DA 2EGIA 5EGJA 1J1YA 3RD7A 4FQ9A 3E29A 1ZHGA 4M20A 4MZQA 4W78B 4XY6A 4RLWA 3R3FA 1LO9A 1MKBA 3KHPA 4K4BA 5SZVA 3EXZA 1VI8A 1T82A 4RLTB 1SBKA 2EISA 3LW3A 5BP2A 3KG6A 2HBOA 4QD7A 1IXLA 2OKIA 3AZ8A 2VZ8A 4HZNA 3CF8A 4RMMA 2FUJA 2OAFA 3ESIA 3R3BA 3R3CA 3IR3A 4R4UA 4XY5A 4ZV3A 4B0JA 2CY9A 1PSUA 3B18A 1WLVA 3LBEA 1WN3A 3OMLA 3HMJG 2GLMA 4K4AA 3HRQA 5SZZA 4GAHA 1LO8A 1VH5A 1BVQA 3B7JA 4I4JA 3R34A 3S4KA 1C8UA 2F41A 2PZHA 3FRNA 3KX7A 2B6EA 3LBBA 4LN9A 4ZJBA 3KUWA 2DSLA 4WNBB 2UV8G 5T02A 5BUXA 4RV2A 1Q4TA 2F0XA 3CF9A 2VKZG 3P2RA 4CL6A 4E3EA 3LZ7A 5HMCA 1S5UA 2EGRA 3RQBA 3U0AA 1VH9A 2GF6A 2GLLA 5EO2A 2PIMA 2VZ9A 4RV2B 1MKAA 4K4CA 4OOCA 2B3MA 1NJKA 4HZPA 2O6TA 4RLWB 5DM5A 2BI0A 3KVIA 5SZUA 1SH8A 1S9CA 2Q2BA 3DP3A 1U1ZA 2F3XA 2Q78A 5KKUA 4NCPA 4B0IA 1OHFA 3D6XA 3DP2A 1SC0A 3P3FA 4ZRFA 3ZH7A 3AZ9A 5EO4A 1VPMA 1TBUA 3DOZA 4MOCA 4K00A 5BYUA 2GLVA 5BUYA 4FFUA 3WEWA 3TEAA 3R37A 3KH8A 2W3XA 3R35A 4K49A 4B8UA 1Z54A 2PFCA 3ZH7B 2OV9A 2AV9A 4ORDA 4ZW0A 5KL9A 4W78A 5EGLA 2O6BA 2V1OA 4IENA 1LO7A 1Q6WA 3B7KA 3SPSA 4K02A 5HMBA 4K4DA 4R9ZA 4AE7A 4QD9A 5BP3A 3E8PA 4I45A 1YOCA 1PN2A 3CK1A 3K67A 2HX5A 3BJKA 3GEKA 3KV8A 3P3IA 3Q62A 4HZOA 5T06A 3QOOA 5HWFA 2CWZA 5EP5A 5HD6A 1WM6A 2ESSA 3AZBA 3QY3A 3D6LA 3ZH5A 3ZH6A 3HDUA 4GAKA 5CPGA 3KV7A 4RLJA 4KEHA 2OIWA 1Q4SA 4B0CA 2O6UA 3KG9A 3HRRA 3BNVA 3D04A 3F5OA 1WLUA 5SZYA 1YLIA 4I82A 4RLJB 3ED0A 3KVZA 3DP0A 2CYEA 3E1EA 1ZKIA 1IQ6A 4OOBA 2XFLA 4B0BA 3KVUA 2QQ2A 3EL6A 4QFWA 2GLPA 3P2SA 3KG8A
chains in the Genus database with same CATH topology
5E1VA 3RD7A 2VKZG 4R9ZA 5BP3A 3RQBA 3U0AA 2QQPA 5BP2A 3KG6A 2VZ9A 4OOCA 3CJYA 2VZ8A 3ZH5A 3ZH6A 5KKUA 4U3VA 4R4UA 1OHFA 3KG9A 3HRRA 3S6PA 3B18A 3KG7A 3ZH7A 3HMJG 3HRQA 3ZH7B 2PFCA 3FRNA 4LN9A 3EL6A 4QFWA 3BBJA 3KG8A 2UV8G 4KC5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R4U A;  3RD7 A;  4R9Z A;  3CJY A;  4QFW A;  3BBJ A;  3RQB A;  3U0A A; 
#chains in the Genus database with same CATH topology
 1Q4U A;  4QDB A;  5E1V A;  5T07 A;  4A0Y A;  4YBV A;  3DP1 A;  4I83 A;  3LWG A;  4QD8 A;  2HLJ A;  3NWZ A;  3LMB A;  2EGJ A;  4ZRB A;  2QQP A;  3KX8 A;  4RLU A;  1Z6B A;  2C2I A;  3R87 A;  1PN4 A;  3CJY A;  2XEM A;  3HM0 A;  4H4G A;  1Y7U A;  4RLU B;  4U3V A;  4A12 A;  2FS2 A;  4MOB A;  2PRX A;  3S6P A;  3KG7 A;  2OKH A;  2O5U A;  2OWN A;  3F1T A;  3P2Q A;  3DOY A;  4MTU A;  4WNB A;  2NUJ A;  4A0X A;  2QWZ A;  5HZ4 A;  5EGK A;  5BUW A;  3R32 A;  2GVH A;  3AZA A;  2H4U A;  3R36 A;  4QDA A;  5F6R A;  3BBJ A;  3KUV A;  3KW1 A;  3R3A A;  3DKZ A;  4AE8 A;  5DIO A;  4A0Z A;  4RLT A;  4KC5 A;  3R3D A;  2EGI A;  5EGJ A;  1J1Y A;  3RD7 A;  4FQ9 A;  3E29 A;  1ZHG A;  4M20 A;  4MZQ A;  4W78 B;  4XY6 A;  4RLW A;  3R3F A;  1LO9 A;  1MKB A;  3KHP A;  4K4B A;  5SZV A;  3EXZ A;  1VI8 A;  1T82 A;  4RLT B;  1SBK A;  2EIS A;  3LW3 A;  5BP2 A;  3KG6 A;  2HBO A;  4QD7 A;  1IXL A;  2OKI A;  3AZ8 A;  2VZ8 A;  4HZN A;  3CF8 A;  4RMM A;  2FUJ A;  2OAF A;  3ESI A;  3R3B A;  3R3C A;  3IR3 A;  4R4U A;  4XY5 A;  4ZV3 A;  4B0J A;  2CY9 A;  1PSU A;  3B18 A;  1WLV A;  3LBE A;  1WN3 A;  3OML A;  3HMJ G;  2GLM A;  4K4A A;  3HRQ A;  5SZZ A;  4GAH A;  1LO8 A;  1VH5 A;  1BVQ A;  3B7J A;  4I4J A;  3R34 A;  3S4K A;  1C8U A;  2F41 A;  2PZH A;  3FRN A;  3KX7 A;  2B6E A;  3LBB A;  4LN9 A;  4ZJB A;  3KUW A;  2DSL A;  4WNB B;  2UV8 G;  5T02 A;  5BUX A;  4RV2 A;  1Q4T A;  2F0X A;  3CF9 A;  2VKZ G;  3P2R A;  4CL6 A;  4E3E A;  3LZ7 A;  5HMC A;  1S5U A;  2EGR A;  3RQB A;  3U0A A;  1VH9 A;  2GF6 A;  2GLL A;  5EO2 A;  2PIM A;  2VZ9 A;  4RV2 B;  1MKA A;  4K4C A;  4OOC A;  2B3M A;  1NJK A;  4HZP A;  2O6T A;  4RLW B;  5DM5 A;  2BI0 A;  3KVI A;  5SZU A;  1SH8 A;  1S9C A;  2Q2B A;  3DP3 A;  1U1Z A;  2F3X A;  2Q78 A;  5KKU A;  4NCP A;  4B0I A;  1OHF A;  3D6X A;  3DP2 A;  1SC0 A;  3P3F A;  4ZRF A;  3ZH7 A;  3AZ9 A;  5EO4 A;  1VPM A;  1TBU A;  3DOZ A;  4MOC A;  4K00 A;  5BYU A;  2GLV A;  5BUY A;  4FFU A;  3WEW A;  3TEA A;  3R37 A;  3KH8 A;  2W3X A;  3R35 A;  4K49 A;  4B8U A;  1Z54 A;  2PFC A;  3ZH7 B;  2OV9 A;  2AV9 A;  4ORD A;  4ZW0 A;  5KL9 A;  4W78 A;  5EGL A;  2O6B A;  2V1O A;  4IEN A;  1LO7 A;  1Q6W A;  3B7K A;  3SPS A;  4K02 A;  5HMB A;  4K4D A;  4R9Z A;  4AE7 A;  4QD9 A;  5BP3 A;  3E8P A;  4I45 A;  1YOC A;  1PN2 A;  3CK1 A;  3K67 A;  2HX5 A;  3BJK A;  3GEK A;  3KV8 A;  3P3I A;  3Q62 A;  4HZO A;  5T06 A;  3QOO A;  5HWF A;  2CWZ A;  5EP5 A;  5HD6 A;  1WM6 A;  2ESS A;  3AZB A;  3QY3 A;  3D6L A;  3ZH5 A;  3ZH6 A;  3HDU A;  4GAK A;  5CPG A;  3KV7 A;  4RLJ A;  4KEH A;  2OIW A;  1Q4S A;  4B0C A;  2O6U A;  3KG9 A;  3HRR A;  3BNV A;  3D04 A;  3F5O A;  1WLU A;  5SZY A;  1YLI A;  4I82 A;  4RLJ B;  3ED0 A;  3KVZ A;  3DP0 A;  2CYE A;  3E1E A;  1ZKI A;  1IQ6 A;  4OOB A;  2XFL A;  4B0B A;  3KVU A;  2QQ2 A;  3EL6 A;  4QFW A;  2GLP A;  3P2S A;  3KG8 A; 
#chains in the Genus database with same CATH homology
 5E1V A;  3RD7 A;  2VKZ G;  4R9Z A;  5BP3 A;  3RQB A;  3U0A A;  2QQP A;  5BP2 A;  3KG6 A;  2VZ9 A;  4OOC A;  3CJY A;  2VZ8 A;  3ZH5 A;  3ZH6 A;  5KKU A;  4U3V A;  4R4U A;  1OHF A;  3KG9 A;  3HRR A;  3S6P A;  3B18 A;  3KG7 A;  3ZH7 A;  3HMJ G;  3HRQ A;  3ZH7 B;  2PFC A;  3FRN A;  4LN9 A;  3EL6 A;  4QFW A;  3BBJ A;  3KG8 A;  2UV8 G;  4KC5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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