5KKUA

Crystal structure of an n-terminal dehydratase from difficidin assembly line
Total Genus 78
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
294
structure length
286
Chain Sequence
DQVKTFLQKISHTNYIVRDHRVHQIRVLPGVTLIDMLYRLAAGYLGERPIELRQIIFKQPVVTSEEFDKHLYVTFTPARDSWKVEITSEKAKNGTPLGGNRDENMECQLYLQEDAPRAKELNIEAFMKNASRKWDMHDIYGIARRSHIEHGEFMKNEGAVYQLQDKEELMELTLSDLAEGFREKFKAHPAFLDASTLAGSSFALPYIPFMIDRFCMYQPFPKTIYTYSAKNSRTESGVSDSEPDVYSADFTIYDRAGNVLAECEKLTVKRVRQANMITHLEHHHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A Dehydratase Provides Insights into Split Bimodules and Polypeptide Docking in trans-AT Polyketide Synthases
rcsb
molecule tags Lyase
source organism Bacillus amyloliquefaciens
molecule keywords Polyketide synthase type I
total genus 78
structure length 286
sequence length 294
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2016-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14765 PS-DH Polyketide synthase dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 5kkuA00
4U3VA 3HRQA 5BP3A 3HRRA 3KG9A 2VZ9A 5KKUA 4KC5A 3KG6A 5BP2A 3KG7A 4OOCA 5E1VA 3EL6A 2VZ8A 4LN9A
chains in the Genus database with same CATH superfamily
4K4AA 3AZAA 1J1YA 3RQBA 1NJKA 3KW1A 2C2IA 3QY3A 1LO9A 3KV8A 1Q4TA 3KH8A 3U0AA 1SH8A 2O6TA 1WN3A 5HD6A 2VZ8A 3KVZA 1Y7UA 5EP5A 5KL9A 3LBBA 3D04A 4NCPA 4RLWB 2XEMA 2H4UA 2PFCA 4FFUA 4B0CA 2Q2BA 5HZ4A 1WLVA 4KC5A 4WNBB 3DP2A 4W78A 5HMBA 4RLUB 3EL6A 3R3DA 2EISA 3R35A 5EGKA 3S6PA 5SZUA 4XY6A 3OMLA 2CYEA 2V1OA 1IXLA 3E29A 2O5UA 4B0JA 1Q6WA 3Q62A 4RLJB 4CL6A 4B0BA 3ZH6A 4MOCA 3CK1A 1OHFA 2NUJA 1SBKA 3DOZA 3E8PA 4R4UA 1ZHGA 3KUVA 2VKZG 3R3FA 5E1VA 1S5UA 2EGRA 2QQ2A 4HZOA 4LN9A 1PSUA 3LZ7A 4ZRFA 3CJYA 4I4JA 5SZVA 4RMMA 1MKBA 4AE7A 4A0XA 1LO8A 3B18A 4K4BA 1VH9A 4QD7A 4OOCA 3R3CA 2O6BA 4ZW0A 5KKUA 3P2QA 5EO2A 3K67A 5DM5A 4RLTA 2Q78A 2GLLA 3FRNA 3P2RA 5BUYA 1T82A 1YOCA 2HX5A 2DSLA 4K4DA 3CF8A 4RV2B 4MTUA 4KEHA 4QD9A 4U3VA 4QDBA 5T06A 4B8UA 1TBUA 3ZH7A 5DIOA 4HZPA 3KX7A 5CPGA 2F41A 4I45A 5EO4A 1YLIA 1WM6A 4I83A 2OIWA 3KG6A 2GF6A 3P2SA 3BBJA 4ZV3A 4A0YA 2OKHA 2OV9A 4I82A 1PN4A 4QFWA 3KVUA 4W78B 1Q4UA 4K4CA 2GLVA 3KG9A 3KV7A 2OKIA 2GVHA 3LMBA 1C8UA 4HZNA 4ZRBA 3P3FA 5EGJA 3DP3A 2GLMA 2B3MA 2GLPA 5BYUA 5EGLA 3HM0A 3R36A 2PIMA 4YBVA 3F5OA 4MOBA 3KG7A 3IR3A 1VI8A 3LWGA 2O6UA 3GEKA 1S9CA 3LBEA 2FS2A 5T07A 5HMCA 3HRQA 1IQ6A 3AZBA 4K00A 3AZ9A 2B6EA 3WEWA 4K49A 4GAHA 1VH5A 1Z6BA 2OAFA 2PZHA 3HDUA 3D6XA 3R87A 5F6RA 5BUXA 3AZ8A 4RLWA 4A12A 3F1TA 3ED0A 2ESSA 4E3EA 1WLUA 1U1ZA 4MZQA 4WNBA 5T02A 5HWFA 3RD7A 3R3BA 3R34A 4OOBA 4RLUA 3TEAA 3BJKA 3ZH5A 2BI0A 3D6LA 3DP1A 3DP0A 4RLTB 4ORDA 3R3AA 3BNVA 3LW3A 3KG8A 4R9ZA 5BP3A 3R37A 3QOOA 3KHPA 4FQ9A 3S4KA 4RLJA 2EGIA 5BUWA 3ZH7B 2CWZA 1ZKIA 4QD8A 1VPMA 4QDAA 5BP2A 3E1EA 2F3XA 3R32A 2FUJA 2PRXA 3HRRA 4AE8A 3DKZA 3HMJG 2XFLA 4B0IA 3B7KA 4GAKA 3SPSA 4IENA 2W3XA 3ESIA 2OWNA 2UV8G 3EXZA 2VZ9A 4H4GA 4K02A 3NWZA 4A0ZA 3KX8A 3DOYA 4XY5A 2F0XA 1PN2A 1LO7A 2HBOA 4M20A 1Z54A 3P3IA 3KUWA 1MKAA 5SZZA 2CY9A 1Q4SA 1SC0A 3CF9A 3KVIA 1BVQA 2QQPA 2HLJA 2AV9A 4RV2A 5SZYA 2EGJA 2QWZA 3B7JA 4ZJBA
chains in the Genus database with same CATH topology
5BP3A 3CJYA 3KG8A 4R9ZA 3KG9A 3RQBA 3U0AA 3B18A 3ZH7B 2VZ8A 4OOCA 5BP2A 3HRRA 2PFCA 5KKUA 3HMJG 4KC5A 3FRNA 3KG7A 3EL6A 3S6PA 4U3VA 3HRQA 2UV8G 2VZ9A 3ZH7A 3ZH6A 1OHFA 3RD7A 4R4UA 2QQPA 3KG6A 2VKZG 3ZH5A 3BBJA 5E1VA 4QFWA 4LN9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U3V A;  3HRQ A;  5BP3 A;  3HRR A;  3KG9 A;  2VZ9 A;  5KKU A;  4KC5 A;  3KG6 A;  5BP2 A;  3KG7 A;  4OOC A;  5E1V A;  3EL6 A;  2VZ8 A;  4LN9 A; 
#chains in the Genus database with same CATH topology
 4K4A A;  3AZA A;  1J1Y A;  3RQB A;  1NJK A;  3KW1 A;  2C2I A;  3QY3 A;  1LO9 A;  3KV8 A;  1Q4T A;  3KH8 A;  3U0A A;  1SH8 A;  2O6T A;  1WN3 A;  5HD6 A;  2VZ8 A;  3KVZ A;  1Y7U A;  5EP5 A;  5KL9 A;  3LBB A;  3D04 A;  4NCP A;  4RLW B;  2XEM A;  2H4U A;  2PFC A;  4FFU A;  4B0C A;  2Q2B A;  5HZ4 A;  1WLV A;  4KC5 A;  4WNB B;  3DP2 A;  4W78 A;  5HMB A;  4RLU B;  3EL6 A;  3R3D A;  2EIS A;  3R35 A;  5EGK A;  3S6P A;  5SZU A;  4XY6 A;  3OML A;  2CYE A;  2V1O A;  1IXL A;  3E29 A;  2O5U A;  4B0J A;  1Q6W A;  3Q62 A;  4RLJ B;  4CL6 A;  4B0B A;  3ZH6 A;  4MOC A;  3CK1 A;  1OHF A;  2NUJ A;  1SBK A;  3DOZ A;  3E8P A;  4R4U A;  1ZHG A;  3KUV A;  2VKZ G;  3R3F A;  5E1V A;  1S5U A;  2EGR A;  2QQ2 A;  4HZO A;  4LN9 A;  1PSU A;  3LZ7 A;  4ZRF A;  3CJY A;  4I4J A;  5SZV A;  4RMM A;  1MKB A;  4AE7 A;  4A0X A;  1LO8 A;  3B18 A;  4K4B A;  1VH9 A;  4QD7 A;  4OOC A;  3R3C A;  2O6B A;  4ZW0 A;  5KKU A;  3P2Q A;  5EO2 A;  3K67 A;  5DM5 A;  4RLT A;  2Q78 A;  2GLL A;  3FRN A;  3P2R A;  5BUY A;  1T82 A;  1YOC A;  2HX5 A;  2DSL A;  4K4D A;  3CF8 A;  4RV2 B;  4MTU A;  4KEH A;  4QD9 A;  4U3V A;  4QDB A;  5T06 A;  4B8U A;  1TBU A;  3ZH7 A;  5DIO A;  4HZP A;  3KX7 A;  5CPG A;  2F41 A;  4I45 A;  5EO4 A;  1YLI A;  1WM6 A;  4I83 A;  2OIW A;  3KG6 A;  2GF6 A;  3P2S A;  3BBJ A;  4ZV3 A;  4A0Y A;  2OKH A;  2OV9 A;  4I82 A;  1PN4 A;  4QFW A;  3KVU A;  4W78 B;  1Q4U A;  4K4C A;  2GLV A;  3KG9 A;  3KV7 A;  2OKI A;  2GVH A;  3LMB A;  1C8U A;  4HZN A;  4ZRB A;  3P3F A;  5EGJ A;  3DP3 A;  2GLM A;  2B3M A;  2GLP A;  5BYU A;  5EGL A;  3HM0 A;  3R36 A;  2PIM A;  4YBV A;  3F5O A;  4MOB A;  3KG7 A;  3IR3 A;  1VI8 A;  3LWG A;  2O6U A;  3GEK A;  1S9C A;  3LBE A;  2FS2 A;  5T07 A;  5HMC A;  3HRQ A;  1IQ6 A;  3AZB A;  4K00 A;  3AZ9 A;  2B6E A;  3WEW A;  4K49 A;  4GAH A;  1VH5 A;  1Z6B A;  2OAF A;  2PZH A;  3HDU A;  3D6X A;  3R87 A;  5F6R A;  5BUX A;  3AZ8 A;  4RLW A;  4A12 A;  3F1T A;  3ED0 A;  2ESS A;  4E3E A;  1WLU A;  1U1Z A;  4MZQ A;  4WNB A;  5T02 A;  5HWF A;  3RD7 A;  3R3B A;  3R34 A;  4OOB A;  4RLU A;  3TEA A;  3BJK A;  3ZH5 A;  2BI0 A;  3D6L A;  3DP1 A;  3DP0 A;  4RLT B;  4ORD A;  3R3A A;  3BNV A;  3LW3 A;  3KG8 A;  4R9Z A;  5BP3 A;  3R37 A;  3QOO A;  3KHP A;  4FQ9 A;  3S4K A;  4RLJ A;  2EGI A;  5BUW A;  3ZH7 B;  2CWZ A;  1ZKI A;  4QD8 A;  1VPM A;  4QDA A;  5BP2 A;  3E1E A;  2F3X A;  3R32 A;  2FUJ A;  2PRX A;  3HRR A;  4AE8 A;  3DKZ A;  3HMJ G;  2XFL A;  4B0I A;  3B7K A;  4GAK A;  3SPS A;  4IEN A;  2W3X A;  3ESI A;  2OWN A;  2UV8 G;  3EXZ A;  2VZ9 A;  4H4G A;  4K02 A;  3NWZ A;  4A0Z A;  3KX8 A;  3DOY A;  4XY5 A;  2F0X A;  1PN2 A;  1LO7 A;  2HBO A;  4M20 A;  1Z54 A;  3P3I A;  3KUW A;  1MKA A;  5SZZ A;  2CY9 A;  1Q4S A;  1SC0 A;  3CF9 A;  3KVI A;  1BVQ A;  2QQP A;  2HLJ A;  2AV9 A;  4RV2 A;  5SZY A;  2EGJ A;  2QWZ A;  3B7J A;  4ZJB A; 
#chains in the Genus database with same CATH homology
 5BP3 A;  3CJY A;  3KG8 A;  4R9Z A;  3KG9 A;  3RQB A;  3U0A A;  3B18 A;  3ZH7 B;  2VZ8 A;  4OOC A;  5BP2 A;  3HRR A;  2PFC A;  5KKU A;  3HMJ G;  4KC5 A;  3FRN A;  3KG7 A;  3EL6 A;  3S6P A;  4U3V A;  3HRQ A;  2UV8 G;  2VZ9 A;  3ZH7 A;  3ZH6 A;  1OHF A;  3RD7 A;  4R4U A;  2QQP A;  3KG6 A;  2VKZ G;  3ZH5 A;  3BBJ A;  5E1V A;  4QFW A;  4LN9 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...