3S15E

Rna polymerase ii initiation complex with a 7-nt rna
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 64
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s15E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s15E02
5IYBE 4A3FE 1I50E 2WB1H 1TWHE 4C2ME 3S17E 4C3HE 4C3IE 2E2HE 2NVQE 2R93E 2JA8E 3GTOE 4A3BE 3FKIE 3I4NE 5IP9E 1Y1VE 3S1NE 4Y7NE 3K7AE 4A3LE 2PMZH 1EIKA 5IYDE 2YU9E 3S2HE 3S16E 1TWCE 3GTLE 3GTQE 4A3ME 4BBSE 1I3QE 5M5YE 1R9TE 4A3DE 5C44E 3S15E 2R7ZE 3GTJE 4X6AE 1TWAE 3PO2E 3CQZE 3HOZE 4BY1E 1DZFA 5IP7E 5M5XE 4A3KE 3HKZH 4A3EE 4A93E 3M3YE 3I4ME 3HOUE 5M3ME 4A3JE 4A3GE 2JA5E 1WCME 3GTGE 5FLME 3S2DE 3M4OE 4C3JE 1TWGE 3S1QE 5IYCE 4Y52E 2R92E 1TWFE 1SFOE 4BXXE 3HOXE 4A3IE 3GTPE 3HOVE 3H0GE 3S1RE 4BBRE 1I6HE 5C3EE 3HOYE 2NVXE 4AYBH 3S1ME 2E2IE 4QIWH 5C4JE 1Y1WE 2Y0SH 2WAQH 2VUME 3RZDE 4BY7E 5M3FE 3H3VF 2NVTE 2B63E 2NVYE 5C4XE 3RZOE 3GTME 2JA7E 3GTKE 3S14E 5M5WE 3PO3E 2E2JE 3HOWE 2JA6E 4A3CE 1K83E 5FJ8E
chains in the Genus database with same CATH superfamily
5E18E 5IYBE 2R93F 2JA8F 3S14F 4C3IF 4A3FE 4A3BF 1I50E 5M5WF 3PO3F 2WB1H 1TWHE 2E2JF 3HOWF 4C2ME 2JA6F 3K7AF 4Y7NF 4LK0E 5FJ8F 5IYDF 5IYBF 4YG2E 3S17E 4C3HE 1YNNK 4XSXE 3S2HF 3S16F 1I50F 4C3IE 2E2HE 2A6EE 2NVQE 2R93E 4C2MF 4A3MF 2JA8E 3GTOE 4A3BE 1I3QF 3FKIE 3I4NE 5IP9E 2BE5E 1R9TF 2PMZK 2WB1I 4A3DF 1Y1VE 3S1NE 3S15F 3HKZK 3H3VG 2R7ZF 5E17E 3GTJF 3DXJE 4Y7NE 3K7AE 4YFXE 4A3LE 2PMZH 1EIKA 5IYDE 2E2HF 2NVQF 2YU9E 3PO2F 3GTOF 3S2HE 3S16E 3CQZF 1TWCE 3FKIF 4MEYE 5IP9F 4XLPE 3GTLE 4G7HE 3I4NF 1Y1VF 3S1NF 3GTQE 4A3ME 4BBSE 4A3LF 1I3QE 5M5YE 1R9TE 5M5XF 1I6VE 2YU9F 4A3DE 4LJZE 5C44E 3S15E 2R7ZE 1YNJK 3GTJE 1TWCF 4X6AE 5TMFE 3GTLF 1TWAE 5M3MF 4A3GF 3GTQF 3PO2E 4XSZE 4YFNE 4BBSF 3CQZE 3GTGF 5M5YF 4OINE 3HOZE 4XLNE 4BY1E 4OIOE 3M4OF 1DZFA 5C44F 4KN7E 4Q4ZE 4C3JF 4G7OE 4QIWK 5IP7E 2CW0E 4X6AF 5D4CE 4KN4E 5M5XE 5IYCF 4A3KE 3HKZH 1TWAF 1QKLA 4YFKE 4Y52F 2PPBE 4OIQE 3GTMF 1TWFF 4A3EE 4A93E 5D4DE 4BXXF 4A3IF 4MEXE 3HOZF 3M3YE 4OIPE 4BY1F 4OIRE 3I4ME 3HOVF 3HOUE 5M3ME 4A3JE 4A3GE 3S1RF 2JA5E 5IP7F 1WCME 3GTGE 5IPLE 5BYHE 3HOYF 4A3KF 2NVXF 5FLME 3S2DE 3M4OE 1ZYRE 2E2IF 2KRXA 2O5IE 3S1MF 4C3JE 4A3EF 4A93F 1TWGE 3S1QE 4G7ZE 5M3FF 3M3YF 2NVTF 5TMCE 5IYCE 2B63F 3HOUF 4Y52E 2NVYF 4A3JF 3I4MF 2R92E 4MQ9E 1TWFE 2JA5F 3RZOF 1SFOE 1WCMF 1HQME 2A69E 4BXXE 3HOXE 4A3IE 4LK1E 2JA7F 3GTPE 5FLMF 3GTKF 3S2DF 3HOVE 3H0GE 4AYBK 3S1RE 4BBRE 1TWGF 3S1QF 1IW7E 2O5JE 1I6HE 2WAQK 5C3EE 3HOYE 2NVXE 4AYBH 3S1ME 2E2IE 4QIWH 2R92F 5D4EE 5C4JE 4A3CF 1Y1WE 1SFOF 1K83F 2WAQH 2VUME 2Y0SH 3RZDE 4BY7E 3HOXF 3GTPF 5M3FE 4GZYE 3H3VF 2NVTE 3H0GF 2B63E 4ZH4E 2NVYE 5C4XE 4BBRF 4A3FF 3RZOE 3EQLE 3GTME 1TWHF 4Q5SE 5C3EF 1I6HF 2JA7E 3GTKE 5C4JF 3S14E 1Y1WF 2VUMF 4JK1E 4LLGE 5M5WE 4BY7F 3RZDF 3PO3E 4KMUE 2E2JE 3WODE 3S17F 4C3HF 3HOWE 5C4XF 2JA6E 2A68E 4A3CE 1K83E 2A6HE 5FJ8E 2Y0SI 1SMYE
chains in the Genus database with same CATH topology
5IYBE 4A3FE 1I50E 2WB1H 1TWHE 4C2ME 3S17E 4C3HE 4C3IE 2E2HE 2NVQE 2R93E 2JA8E 3GTOE 4A3BE 3FKIE 3I4NE 5IP9E 1Y1VE 3S1NE 4Y7NE 3K7AE 4A3LE 2PMZH 1EIKA 5IYDE 2YU9E 3S2HE 3S16E 1TWCE 3GTLE 3GTQE 4A3ME 4BBSE 1I3QE 5M5YE 1R9TE 4A3DE 5C44E 3S15E 2R7ZE 3GTJE 4X6AE 1TWAE 3PO2E 3CQZE 3HOZE 4BY1E 1DZFA 5IP7E 5M5XE 4A3KE 3HKZH 4A3EE 4A93E 3M3YE 3I4ME 3HOUE 5M3ME 4A3JE 4A3GE 2JA5E 1WCME 3GTGE 5FLME 3S2DE 3M4OE 4C3JE 1TWGE 3S1QE 5IYCE 4Y52E 2R92E 1TWFE 1SFOE 4BXXE 3HOXE 4A3IE 3GTPE 3HOVE 3H0GE 3S1RE 4BBRE 1I6HE 5C3EE 3HOYE 2NVXE 4AYBH 3S1ME 2E2IE 4QIWH 5C4JE 1Y1WE 2Y0SH 2WAQH 2VUME 3RZDE 4BY7E 5M3FE 3H3VF 2NVTE 2B63E 2NVYE 5C4XE 3RZOE 3GTME 2JA7E 3GTKE 3S14E 5M5WE 3PO3E 2E2JE 3HOWE 2JA6E 4A3CE 1K83E 5FJ8E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYB E;  4A3F E;  1I50 E;  2WB1 H;  1TWH E;  4C2M E;  3S17 E;  4C3H E;  4C3I E;  2E2H E;  2NVQ E;  2R93 E;  2JA8 E;  3GTO E;  4A3B E;  3FKI E;  3I4N E;  5IP9 E;  1Y1V E;  3S1N E;  4Y7N E;  3K7A E;  4A3L E;  2PMZ H;  1EIK A;  5IYD E;  2YU9 E;  3S2H E;  3S16 E;  1TWC E;  3GTL E;  3GTQ E;  4A3M E;  4BBS E;  1I3Q E;  5M5Y E;  1R9T E;  4A3D E;  5C44 E;  3S15 E;  2R7Z E;  3GTJ E;  4X6A E;  1TWA E;  3PO2 E;  3CQZ E;  3HOZ E;  4BY1 E;  1DZF A;  5IP7 E;  5M5X E;  4A3K E;  3HKZ H;  4A3E E;  4A93 E;  3M3Y E;  3I4M E;  3HOU E;  5M3M E;  4A3J E;  4A3G E;  2JA5 E;  1WCM E;  3GTG E;  5FLM E;  3S2D E;  3M4O E;  4C3J E;  1TWG E;  3S1Q E;  5IYC E;  4Y52 E;  2R92 E;  1TWF E;  1SFO E;  4BXX E;  3HOX E;  4A3I E;  3GTP E;  3HOV E;  3H0G E;  3S1R E;  4BBR E;  1I6H E;  5C3E E;  3HOY E;  2NVX E;  4AYB H;  3S1M E;  2E2I E;  4QIW H;  5C4J E;  1Y1W E;  2Y0S H;  2WAQ H;  2VUM E;  3RZD E;  4BY7 E;  5M3F E;  3H3V F;  2NVT E;  2B63 E;  2NVY E;  5C4X E;  3RZO E;  3GTM E;  2JA7 E;  3GTK E;  3S14 E;  5M5W E;  3PO3 E;  2E2J E;  3HOW E;  2JA6 E;  4A3C E;  1K83 E;  5FJ8 E; 
#chains in the Genus database with same CATH topology
 5E18 E;  5IYB E;  2R93 F;  2JA8 F;  3S14 F;  4C3I F;  4A3F E;  4A3B F;  1I50 E;  5M5W F;  3PO3 F;  2WB1 H;  1TWH E;  2E2J F;  3HOW F;  4C2M E;  2JA6 F;  3K7A F;  4Y7N F;  4LK0 E;  5FJ8 F;  5IYD F;  5IYB F;  4YG2 E;  3S17 E;  4C3H E;  1YNN K;  4XSX E;  3S2H F;  3S16 F;  1I50 F;  4C3I E;  2E2H E;  2A6E E;  2NVQ E;  2R93 E;  4C2M F;  4A3M F;  2JA8 E;  3GTO E;  4A3B E;  1I3Q F;  3FKI E;  3I4N E;  5IP9 E;  2BE5 E;  1R9T F;  2PMZ K;  2WB1 I;  4A3D F;  1Y1V E;  3S1N E;  3S15 F;  3HKZ K;  3H3V G;  2R7Z F;  5E17 E;  3GTJ F;  3DXJ E;  4Y7N E;  3K7A E;  4YFX E;  4A3L E;  2PMZ H;  1EIK A;  5IYD E;  2E2H F;  2NVQ F;  2YU9 E;  3PO2 F;  3GTO F;  3S2H E;  3S16 E;  3CQZ F;  1TWC E;  3FKI F;  4MEY E;  5IP9 F;  4XLP E;  3GTL E;  4G7H E;  3I4N F;  1Y1V F;  3S1N F;  3GTQ E;  4A3M E;  4BBS E;  4A3L F;  1I3Q E;  5M5Y E;  1R9T E;  5M5X F;  1I6V E;  2YU9 F;  4A3D E;  4LJZ E;  5C44 E;  3S15 E;  2R7Z E;  1YNJ K;  3GTJ E;  1TWC F;  4X6A E;  5TMF E;  3GTL F;  1TWA E;  5M3M F;  4A3G F;  3GTQ F;  3PO2 E;  4XSZ E;  4YFN E;  4BBS F;  3CQZ E;  3GTG F;  5M5Y F;  4OIN E;  3HOZ E;  4XLN E;  4BY1 E;  4OIO E;  3M4O F;  1DZF A;  5C44 F;  4KN7 E;  4Q4Z E;  4C3J F;  4G7O E;  4QIW K;  5IP7 E;  2CW0 E;  4X6A F;  5D4C E;  4KN4 E;  5M5X E;  5IYC F;  4A3K E;  3HKZ H;  1TWA F;  1QKL A;  4YFK E;  4Y52 F;  2PPB E;  4OIQ E;  3GTM F;  1TWF F;  4A3E E;  4A93 E;  5D4D E;  4BXX F;  4A3I F;  4MEX E;  3HOZ F;  3M3Y E;  4OIP E;  4BY1 F;  4OIR E;  3I4M E;  3HOV F;  3HOU E;  5M3M E;  4A3J E;  4A3G E;  3S1R F;  2JA5 E;  5IP7 F;  1WCM E;  3GTG E;  5IPL E;  5BYH E;  3HOY F;  4A3K F;  2NVX F;  5FLM E;  3S2D E;  3M4O E;  1ZYR E;  2E2I F;  2KRX A;  2O5I E;  3S1M F;  4C3J E;  4A3E F;  4A93 F;  1TWG E;  3S1Q E;  4G7Z E;  5M3F F;  3M3Y F;  2NVT F;  5TMC E;  5IYC E;  2B63 F;  3HOU F;  4Y52 E;  2NVY F;  4A3J F;  3I4M F;  2R92 E;  4MQ9 E;  1TWF E;  2JA5 F;  3RZO F;  1SFO E;  1WCM F;  1HQM E;  2A69 E;  4BXX E;  3HOX E;  4A3I E;  4LK1 E;  2JA7 F;  3GTP E;  5FLM F;  3GTK F;  3S2D F;  3HOV E;  3H0G E;  4AYB K;  3S1R E;  4BBR E;  1TWG F;  3S1Q F;  1IW7 E;  2O5J E;  1I6H E;  2WAQ K;  5C3E E;  3HOY E;  2NVX E;  4AYB H;  3S1M E;  2E2I E;  4QIW H;  2R92 F;  5D4E E;  5C4J E;  4A3C F;  1Y1W E;  1SFO F;  1K83 F;  2WAQ H;  2VUM E;  2Y0S H;  3RZD E;  4BY7 E;  3HOX F;  3GTP F;  5M3F E;  4GZY E;  3H3V F;  2NVT E;  3H0G F;  2B63 E;  4ZH4 E;  2NVY E;  5C4X E;  4BBR F;  4A3F F;  3RZO E;  3EQL E;  3GTM E;  1TWH F;  4Q5S E;  5C3E F;  1I6H F;  2JA7 E;  3GTK E;  5C4J F;  3S14 E;  1Y1W F;  2VUM F;  4JK1 E;  4LLG E;  5M5W E;  4BY7 F;  3RZD F;  3PO3 E;  4KMU E;  2E2J E;  3WOD E;  3S17 F;  4C3H F;  3HOW E;  5C4X F;  2JA6 E;  2A68 E;  4A3C E;  1K83 E;  2A6H E;  5FJ8 E;  2Y0S I;  1SMY E; 
#chains in the Genus database with same CATH homology
 5IYB E;  4A3F E;  1I50 E;  2WB1 H;  1TWH E;  4C2M E;  3S17 E;  4C3H E;  4C3I E;  2E2H E;  2NVQ E;  2R93 E;  2JA8 E;  3GTO E;  4A3B E;  3FKI E;  3I4N E;  5IP9 E;  1Y1V E;  3S1N E;  4Y7N E;  3K7A E;  4A3L E;  2PMZ H;  1EIK A;  5IYD E;  2YU9 E;  3S2H E;  3S16 E;  1TWC E;  3GTL E;  3GTQ E;  4A3M E;  4BBS E;  1I3Q E;  5M5Y E;  1R9T E;  4A3D E;  5C44 E;  3S15 E;  2R7Z E;  3GTJ E;  4X6A E;  1TWA E;  3PO2 E;  3CQZ E;  3HOZ E;  4BY1 E;  1DZF A;  5IP7 E;  5M5X E;  4A3K E;  3HKZ H;  4A3E E;  4A93 E;  3M3Y E;  3I4M E;  3HOU E;  5M3M E;  4A3J E;  4A3G E;  2JA5 E;  1WCM E;  3GTG E;  5FLM E;  3S2D E;  3M4O E;  4C3J E;  1TWG E;  3S1Q E;  5IYC E;  4Y52 E;  2R92 E;  1TWF E;  1SFO E;  4BXX E;  3HOX E;  4A3I E;  3GTP E;  3HOV E;  3H0G E;  3S1R E;  4BBR E;  1I6H E;  5C3E E;  3HOY E;  2NVX E;  4AYB H;  3S1M E;  2E2I E;  4QIW H;  5C4J E;  1Y1W E;  2Y0S H;  2WAQ H;  2VUM E;  3RZD E;  4BY7 E;  5M3F E;  3H3V F;  2NVT E;  2B63 E;  2NVY E;  5C4X E;  3RZO E;  3GTM E;  2JA7 E;  3GTK E;  3S14 E;  5M5W E;  3PO3 E;  2E2J E;  3HOW E;  2JA6 E;  4A3C E;  1K83 E;  5FJ8 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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