3S17E

Rna polymerase ii initiation complex with a 9-nt rna
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 56
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s17E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s17E02
1TWAE 4Y7NE 3GTOE 5FLME 4BY7E 2JA7E 1TWGE 2E2HE 5IYCE 2NVXE 2WAQH 1DZFA 3HOXE 1I3QE 1WCME 4QIWH 4BXXE 4BY1E 3RZDE 3S1NE 4A3LE 3M3YE 4A3EE 2Y0SH 2E2IE 3HOYE 2YU9E 5M5YE 3CQZE 4A3KE 1I50E 2WB1H 3HKZH 1SFOE 3GTKE 2E2JE 5M5WE 2JA5E 1TWHE 3S17E 2NVQE 3GTGE 1TWCE 3FKIE 3I4NE 3K7AE 4AYBH 2NVYE 3S14E 5IYBE 3S2HE 3HOWE 3HOUE 5C44E 3S1QE 1Y1WE 4A3IE 3GTLE 3HOVE 3RZOE 2JA6E 3H3VF 5IP9E 5IYDE 5M5XE 3S16E 1I6HE 4Y52E 4A3DE 4A3CE 1K83E 3S2DE 3S15E 2R92E 4BBRE 3PO3E 4C3HE 4A93E 3S1ME 4X6AE 1Y1VE 4C3JE 5C3EE 2NVTE 5FJ8E 3GTME 4C2ME 3H0GE 3S1RE 5M3ME 4A3JE 3M4OE 3PO2E 4C3IE 5IP7E 5C4XE 3GTJE 4A3BE 4A3FE 2JA8E 4A3ME 2B63E 1EIKA 4BBSE 2R7ZE 3HOZE 1TWFE 2VUME 3I4ME 1R9TE 5C4JE 3GTPE 5M3FE 3GTQE 2PMZH 4A3GE 2R93E
chains in the Genus database with same CATH superfamily
3GTMF 4C2MF 2WB1I 3H0GF 3S1RF 1TWAE 4Y7NE 4A3JF 3M4OF 3GTOE 5FLME 4YFKE 3PO2F 4BY7E 4C3IF 5IP7F 2JA7E 5C4XF 1TWGE 3GTJF 4A3BF 4A3FF 2JA8F 2E2HE 5IYCE 2NVXE 2WAQH 1DZFA 4A3MF 3HOXE 1I3QE 2B63F 4G7OE 1WCME 2BE5E 4OINE 4QIWH 4BBSF 1ZYRE 2WAQK 4BXXE 4OIRE 3HOZF 1HQME 2R7ZF 4BY1E 1TWFF 2VUMF 3RZDE 3I4MF 3S1NE 5D4CE 1R9TF 5C4JF 2O5JE 4A3LE 3M3YE 4KN4E 5M3FF 3GTPF 4A3EE 3GTQF 2Y0SH 4OIOE 2E2IE 1SMYE 3HOYE 4A3GF 2YU9E 5M5YE 2R93F 1QKLA 3CQZE 4A3KE 1I50E 2WB1H 3DXJE 3HKZH 1SFOE 1TWAF 4KMUE 4Y7NF 5M3MF 3GTOF 1I6VE 5FLMF 3GTKE 4BY7F 2JA7F 2A6EE 1TWGF 2PMZK 2E2JE 2E2HF 5M5WE 4Q4ZE 5IYCF 2NVXF 3HOXF 1I3QF 2JA5E 1WCMF 1TWHE 5TMCE 3S17E 1IW7E 4MEYE 2NVQE 3WODE 4XSXE 3GTGE 1TWCE 4BXXF 3FKIE 4BY1F 3I4NE 4OIPE 3K7AE 4AYBH 2NVYE 3S14E 3RZDF 3S1NF 5IYBE 4A3LF 3S2HE 3M3YF 4QIWK 4A3EF 3HOWE 3HOUE 5C44E 2E2IF 3HOYF 1YNJK 2YU9F 2PPBE 4XLNE 5M5YF 3S1QE 1Y1WE 4A3IE 3CQZF 4A3KF 1I50F 4LJZE 4C3JF 3GTLE 4OIQE 5IPLE 3HOVE 3GTKF 4Q5SE 3RZOE 2JA6E 3H3VF 4MEXE 5IP9E 5IYDE 5M5XE 2E2JF 3S16E 2A6HE 1I6HE 4Y52E 4A3DE 3HKZK 4A3CE 2A68E 5M5WF 2JA5F 2O5IE 1TWHF 4YG2E 3S17F 2NVQF 1K83E 3S2DE 3S15E 5E18E 3H3VG 2R92E 4BBRE 3GTGF 2A69E 3PO3E 1TWCF 5C3EF 4C3HE 4A93E 2CW0E 4LK0E 3S1ME 3I4NF 3K7AF 2NVYF 3S14F 4X6AE 5IYBF 3S2HF 3EQLE 1Y1VE 4YFXE 4C3JE 2KRXA 5C3EE 2NVTE 5FJ8E 5C44F 3HOWF 3GTME 4C2ME 3H0GE 3S1RE 4AYBK 4JK1E 5M3ME 4A3JE 3M4OE 5E17E 3S1QF 1Y1WF 4A3IF 3PO2E 4C3IE 5IP7E 5C4XE 4XSZE 3GTLF 1SFOF 4MQ9E 5BYHE 3GTJE 4A3BE 3HOVF 4A3FE 2JA8E 3RZOF 1YNNK 4A3ME 2B63E 4G7ZE 2JA6F 4LLGE 4YFNE 4GZYE 5IP9F 5IYDF 5M5XF 1EIKA 5D4DE 3S16F 4Y52F 1I6HF 4A3DF 4A3CF 4BBSE 4ZH4E 2R7ZE 3HOZE 1K83F 3S2DF 3S15F 1TWFE 2VUME 3I4ME 4KN7E 4BBRF 2R92F 3PO3F 1R9TE 5C4JE 4C3HF 4A93F 3FKIF 3S1MF 3GTPE 5M3FE 4LK1E 4XLPE 4X6AF 3GTQE 2Y0SI 5TMFE 4G7HE 1Y1VF 2PMZH 4A3GE 5D4EE 2NVTF 5FJ8F 2R93E 3HOUF
chains in the Genus database with same CATH topology
1TWAE 4Y7NE 3GTOE 5FLME 4BY7E 2JA7E 1TWGE 2E2HE 5IYCE 2NVXE 2WAQH 1DZFA 3HOXE 1I3QE 1WCME 4QIWH 4BXXE 4BY1E 3RZDE 3S1NE 4A3LE 3M3YE 4A3EE 2Y0SH 2E2IE 3HOYE 2YU9E 5M5YE 3CQZE 4A3KE 1I50E 2WB1H 3HKZH 1SFOE 3GTKE 2E2JE 5M5WE 2JA5E 1TWHE 3S17E 2NVQE 3GTGE 1TWCE 3FKIE 3I4NE 3K7AE 4AYBH 2NVYE 3S14E 5IYBE 3S2HE 3HOWE 3HOUE 5C44E 3S1QE 1Y1WE 4A3IE 3GTLE 3HOVE 3RZOE 2JA6E 3H3VF 5IP9E 5IYDE 5M5XE 3S16E 1I6HE 4Y52E 4A3DE 4A3CE 1K83E 3S2DE 3S15E 2R92E 4BBRE 3PO3E 4C3HE 4A93E 3S1ME 4X6AE 1Y1VE 4C3JE 5C3EE 2NVTE 5FJ8E 3GTME 4C2ME 3H0GE 3S1RE 5M3ME 4A3JE 3M4OE 3PO2E 4C3IE 5IP7E 5C4XE 3GTJE 4A3BE 4A3FE 2JA8E 4A3ME 2B63E 1EIKA 4BBSE 2R7ZE 3HOZE 1TWFE 2VUME 3I4ME 1R9TE 5C4JE 3GTPE 5M3FE 3GTQE 2PMZH 4A3GE 2R93E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWA E;  4Y7N E;  3GTO E;  5FLM E;  4BY7 E;  2JA7 E;  1TWG E;  2E2H E;  5IYC E;  2NVX E;  2WAQ H;  1DZF A;  3HOX E;  1I3Q E;  1WCM E;  4QIW H;  4BXX E;  4BY1 E;  3RZD E;  3S1N E;  4A3L E;  3M3Y E;  4A3E E;  2Y0S H;  2E2I E;  3HOY E;  2YU9 E;  5M5Y E;  3CQZ E;  4A3K E;  1I50 E;  2WB1 H;  3HKZ H;  1SFO E;  3GTK E;  2E2J E;  5M5W E;  2JA5 E;  1TWH E;  3S17 E;  2NVQ E;  3GTG E;  1TWC E;  3FKI E;  3I4N E;  3K7A E;  4AYB H;  2NVY E;  3S14 E;  5IYB E;  3S2H E;  3HOW E;  3HOU E;  5C44 E;  3S1Q E;  1Y1W E;  4A3I E;  3GTL E;  3HOV E;  3RZO E;  2JA6 E;  3H3V F;  5IP9 E;  5IYD E;  5M5X E;  3S16 E;  1I6H E;  4Y52 E;  4A3D E;  4A3C E;  1K83 E;  3S2D E;  3S15 E;  2R92 E;  4BBR E;  3PO3 E;  4C3H E;  4A93 E;  3S1M E;  4X6A E;  1Y1V E;  4C3J E;  5C3E E;  2NVT E;  5FJ8 E;  3GTM E;  4C2M E;  3H0G E;  3S1R E;  5M3M E;  4A3J E;  3M4O E;  3PO2 E;  4C3I E;  5IP7 E;  5C4X E;  3GTJ E;  4A3B E;  4A3F E;  2JA8 E;  4A3M E;  2B63 E;  1EIK A;  4BBS E;  2R7Z E;  3HOZ E;  1TWF E;  2VUM E;  3I4M E;  1R9T E;  5C4J E;  3GTP E;  5M3F E;  3GTQ E;  2PMZ H;  4A3G E;  2R93 E; 
#chains in the Genus database with same CATH topology
 3GTM F;  4C2M F;  2WB1 I;  3H0G F;  3S1R F;  1TWA E;  4Y7N E;  4A3J F;  3M4O F;  3GTO E;  5FLM E;  4YFK E;  3PO2 F;  4BY7 E;  4C3I F;  5IP7 F;  2JA7 E;  5C4X F;  1TWG E;  3GTJ F;  4A3B F;  4A3F F;  2JA8 F;  2E2H E;  5IYC E;  2NVX E;  2WAQ H;  1DZF A;  4A3M F;  3HOX E;  1I3Q E;  2B63 F;  4G7O E;  1WCM E;  2BE5 E;  4OIN E;  4QIW H;  4BBS F;  1ZYR E;  2WAQ K;  4BXX E;  4OIR E;  3HOZ F;  1HQM E;  2R7Z F;  4BY1 E;  1TWF F;  2VUM F;  3RZD E;  3I4M F;  3S1N E;  5D4C E;  1R9T F;  5C4J F;  2O5J E;  4A3L E;  3M3Y E;  4KN4 E;  5M3F F;  3GTP F;  4A3E E;  3GTQ F;  2Y0S H;  4OIO E;  2E2I E;  1SMY E;  3HOY E;  4A3G F;  2YU9 E;  5M5Y E;  2R93 F;  1QKL A;  3CQZ E;  4A3K E;  1I50 E;  2WB1 H;  3DXJ E;  3HKZ H;  1SFO E;  1TWA F;  4KMU E;  4Y7N F;  5M3M F;  3GTO F;  1I6V E;  5FLM F;  3GTK E;  4BY7 F;  2JA7 F;  2A6E E;  1TWG F;  2PMZ K;  2E2J E;  2E2H F;  5M5W E;  4Q4Z E;  5IYC F;  2NVX F;  3HOX F;  1I3Q F;  2JA5 E;  1WCM F;  1TWH E;  5TMC E;  3S17 E;  1IW7 E;  4MEY E;  2NVQ E;  3WOD E;  4XSX E;  3GTG E;  1TWC E;  4BXX F;  3FKI E;  4BY1 F;  3I4N E;  4OIP E;  3K7A E;  4AYB H;  2NVY E;  3S14 E;  3RZD F;  3S1N F;  5IYB E;  4A3L F;  3S2H E;  3M3Y F;  4QIW K;  4A3E F;  3HOW E;  3HOU E;  5C44 E;  2E2I F;  3HOY F;  1YNJ K;  2YU9 F;  2PPB E;  4XLN E;  5M5Y F;  3S1Q E;  1Y1W E;  4A3I E;  3CQZ F;  4A3K F;  1I50 F;  4LJZ E;  4C3J F;  3GTL E;  4OIQ E;  5IPL E;  3HOV E;  3GTK F;  4Q5S E;  3RZO E;  2JA6 E;  3H3V F;  4MEX E;  5IP9 E;  5IYD E;  5M5X E;  2E2J F;  3S16 E;  2A6H E;  1I6H E;  4Y52 E;  4A3D E;  3HKZ K;  4A3C E;  2A68 E;  5M5W F;  2JA5 F;  2O5I E;  1TWH F;  4YG2 E;  3S17 F;  2NVQ F;  1K83 E;  3S2D E;  3S15 E;  5E18 E;  3H3V G;  2R92 E;  4BBR E;  3GTG F;  2A69 E;  3PO3 E;  1TWC F;  5C3E F;  4C3H E;  4A93 E;  2CW0 E;  4LK0 E;  3S1M E;  3I4N F;  3K7A F;  2NVY F;  3S14 F;  4X6A E;  5IYB F;  3S2H F;  3EQL E;  1Y1V E;  4YFX E;  4C3J E;  2KRX A;  5C3E E;  2NVT E;  5FJ8 E;  5C44 F;  3HOW F;  3GTM E;  4C2M E;  3H0G E;  3S1R E;  4AYB K;  4JK1 E;  5M3M E;  4A3J E;  3M4O E;  5E17 E;  3S1Q F;  1Y1W F;  4A3I F;  3PO2 E;  4C3I E;  5IP7 E;  5C4X E;  4XSZ E;  3GTL F;  1SFO F;  4MQ9 E;  5BYH E;  3GTJ E;  4A3B E;  3HOV F;  4A3F E;  2JA8 E;  3RZO F;  1YNN K;  4A3M E;  2B63 E;  4G7Z E;  2JA6 F;  4LLG E;  4YFN E;  4GZY E;  5IP9 F;  5IYD F;  5M5X F;  1EIK A;  5D4D E;  3S16 F;  4Y52 F;  1I6H F;  4A3D F;  4A3C F;  4BBS E;  4ZH4 E;  2R7Z E;  3HOZ E;  1K83 F;  3S2D F;  3S15 F;  1TWF E;  2VUM E;  3I4M E;  4KN7 E;  4BBR F;  2R92 F;  3PO3 F;  1R9T E;  5C4J E;  4C3H F;  4A93 F;  3FKI F;  3S1M F;  3GTP E;  5M3F E;  4LK1 E;  4XLP E;  4X6A F;  3GTQ E;  2Y0S I;  5TMF E;  4G7H E;  1Y1V F;  2PMZ H;  4A3G E;  5D4E E;  2NVT F;  5FJ8 F;  2R93 E;  3HOU F; 
#chains in the Genus database with same CATH homology
 1TWA E;  4Y7N E;  3GTO E;  5FLM E;  4BY7 E;  2JA7 E;  1TWG E;  2E2H E;  5IYC E;  2NVX E;  2WAQ H;  1DZF A;  3HOX E;  1I3Q E;  1WCM E;  4QIW H;  4BXX E;  4BY1 E;  3RZD E;  3S1N E;  4A3L E;  3M3Y E;  4A3E E;  2Y0S H;  2E2I E;  3HOY E;  2YU9 E;  5M5Y E;  3CQZ E;  4A3K E;  1I50 E;  2WB1 H;  3HKZ H;  1SFO E;  3GTK E;  2E2J E;  5M5W E;  2JA5 E;  1TWH E;  3S17 E;  2NVQ E;  3GTG E;  1TWC E;  3FKI E;  3I4N E;  3K7A E;  4AYB H;  2NVY E;  3S14 E;  5IYB E;  3S2H E;  3HOW E;  3HOU E;  5C44 E;  3S1Q E;  1Y1W E;  4A3I E;  3GTL E;  3HOV E;  3RZO E;  2JA6 E;  3H3V F;  5IP9 E;  5IYD E;  5M5X E;  3S16 E;  1I6H E;  4Y52 E;  4A3D E;  4A3C E;  1K83 E;  3S2D E;  3S15 E;  2R92 E;  4BBR E;  3PO3 E;  4C3H E;  4A93 E;  3S1M E;  4X6A E;  1Y1V E;  4C3J E;  5C3E E;  2NVT E;  5FJ8 E;  3GTM E;  4C2M E;  3H0G E;  3S1R E;  5M3M E;  4A3J E;  3M4O E;  3PO2 E;  4C3I E;  5IP7 E;  5C4X E;  3GTJ E;  4A3B E;  4A3F E;  2JA8 E;  4A3M E;  2B63 E;  1EIK A;  4BBS E;  2R7Z E;  3HOZ E;  1TWF E;  2VUM E;  3I4M E;  1R9T E;  5C4J E;  3GTP E;  5M3F E;  3GTQ E;  2PMZ H;  4A3G E;  2R93 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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