3S1ME

Rna polymerase ii initiation complex with a 5-nt rna (variant 1)
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 64
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s1mE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s1mE02
3H3VF 4BY7E 5C4XE 3PO3E 3HOYE 3FKIE 4A3JE 3S2DE 3M4OE 5FLME 2JA5E 2NVYE 2JA7E 1TWHE 3GTME 3HOZE 1Y1WE 2WAQH 4A93E 4A3CE 3S2HE 5M3FE 4A3BE 4BY1E 5M3ME 2R93E 3RZDE 2NVXE 4X6AE 1TWGE 2NVQE 5C3EE 2JA8E 2E2IE 2YU9E 2R7ZE 2JA6E 3GTPE 3HOXE 1WCME 2PMZH 4BBRE 4A3KE 3I4ME 3HOVE 5FJ8E 4A3GE 3GTJE 4A3IE 1R9TE 4A3LE 3S16E 3RZOE 4BXXE 2NVTE 1SFOE 1I6HE 2WB1H 4A3DE 3HOUE 4BBSE 3HKZH 5IYBE 1EIKA 3HOWE 2B63E 5IP7E 3S1RE 1I50E 1TWFE 4C3HE 3S1ME 5C4JE 3S14E 3S1QE 5IYDE 3S15E 3CQZE 1I3QE 5M5XE 3I4NE 3GTLE 5C44E 5M5WE 5IP9E 5M5YE 4A3EE 3GTQE 3M3YE 4C3JE 1TWAE 3GTGE 4C3IE 2E2JE 3H0GE 1DZFA 3S1NE 3GTKE 2E2HE 4AYBH 1Y1VE 4Y7NE 2VUME 3PO2E 4Y52E 1TWCE 2Y0SH 2R92E 4A3FE 4C2ME 4A3ME 4QIWH 3S17E 5IYCE 3K7AE 3GTOE 1K83E
chains in the Genus database with same CATH superfamily
4XSXE 3H3VF 4BY7E 5C4XE 4G7ZE 3PO3E 3HOYE 4KMUE 3FKIE 5IYDF 3I4MF 3S14F 4Q4ZE 4A3JE 3S2DE 5FJ8F 3S1MF 3M4OE 4ZH4E 4MEXE 3S15F 3CQZF 2WAQK 5FLME 2JA5E 2NVYE 2JA7E 1I3QF 4MEYE 4AYBK 3GTJF 5E17E 4YFNE 1R9TF 1QKLA 3I4NF 4KN7E 1TWHE 3GTME 3HOZE 4LK0E 1Y1WE 3S16F 2WAQH 5C44F 5M5WF 4A93E 5M5YF 1I6VE 4A3EF 4Q5SE 3RZOF 4OIRE 4BXXF 2NVTF 4C3JF 1TWAF 1I6HF 3GTGF 4A3CE 3S2HE 4C3IF 5M3FE 2E2JF 4A3BE 4BY1E 1YNNK 1ZYRE 3HOUF 5IYBF 5M3ME 2R93E 3HOWF 4LLGE 2A6HE 3RZDE 2B63F 2NVXE 4X6AE 1TWCF 1TWFF 3WODE 4C3HF 1TWGE 4YFKE 2NVQE 4OIQE 4OIPE 5C3EE 2JA8E 2Y0SI 4XLNE 2E2IE 3S1QF 4XSZE 4XLPE 3S17F 2YU9E 2R7ZE 2JA6E 2A69E 2PMZK 5C4XF 5M5XF 3HOYF 4YFXE 3FKIF 3GTPE 3HOXE 3DXJE 3GTLF 4A3JF 4GZYE 1WCME 3M4OF 1IW7E 2A68E 5IP9F 4G7HE 2PMZH 4BBRE 4A3KE 5FLMF 2NVYF 3GTQF 3M3YF 3I4ME 4JK1E 3HOVE 5FJ8E 1SMYE 1TWHF 2O5IE 3H0GF 1Y1WF 1YNJK 5TMCE 3S1NF 3GTKF 2E2HF 1Y1VF 4A3GE 4YG2E 3GTJE 4A3IE 5TMFE 4Y7NF 1R9TE 2VUMF 3PO2F 4A3LE 4Y52F 3S2HF 3S16E 5M3FF 2R92F 4BY1F 4A3FF 3RZOE 4C2MF 2KRXA 4BXXE 4A3MF 5M3MF 2R93F 2NVTE 1SFOE 2BE5E 3HKZK 1I6HE 5IYCF 3K7AF 2NVXF 2O5JE 3GTOF 1K83F 4A3DE 2WB1H 4LK1E 1HQME 3HOUE 4BBSE 3HKZH 4BY7F 5IYBE 2JA8F 3PO3F 1EIKA 3HOWE 2B63E 5IP7E 3S1RE 2PPBE 2YU9F 3S2DF 1I50E 1TWFE 4C3HE 3S1ME 5C4JE 3H3VG 2JA6F 5D4CE 2JA5F 2JA7F 4G7OE 3S14E 3S1QE 5IYDE 3HOXF 3GTMF 3HOZF 2CW0E 3S15E 3CQZE 4A93F 4BBRF 4A3KF 1I3QE 5M5XE 3EQLE 3I4NE 3GTLE 2A6EE 5BYHE 3HOVF 4A3CF 5C44E 4A3BF 5M5WE 5IP9E 5M5YE 4A3EE 3GTQE 4A3GF 3M3YE 4A3IF 4C3JE 1TWAE 3GTGE 4LJZE 4C3IE 3RZDF 4A3LF 2E2JE 3H0GE 4X6AF 5D4EE 1TWGF 1DZFA 3S1NE 3GTKE 2E2HE 4AYBH 1Y1VE 5C3EF 4OIOE 2NVQF 4Y7NE 2E2IF 2VUME 3PO2E 4Y52E 1SFOF 1TWCE 4KN4E 4QIWK 2Y0SH 4MQ9E 2R7ZF 2R92E 4A3DF 4A3FE 5D4DE 4OINE 4C2ME 4BBSF 4A3ME 2WB1I 4QIWH 3GTPF 3S17E 5IPLE 5IYCE 5IP7F 3K7AE 3S1RF 1WCMF 1I50F 3GTOE 1K83E 5E18E 5C4JF
chains in the Genus database with same CATH topology
3H3VF 4BY7E 5C4XE 3PO3E 3HOYE 3FKIE 4A3JE 3S2DE 3M4OE 5FLME 2JA5E 2NVYE 2JA7E 1TWHE 3GTME 3HOZE 1Y1WE 2WAQH 4A93E 4A3CE 3S2HE 5M3FE 4A3BE 4BY1E 5M3ME 2R93E 3RZDE 2NVXE 4X6AE 1TWGE 2NVQE 5C3EE 2JA8E 2E2IE 2YU9E 2R7ZE 2JA6E 3GTPE 3HOXE 1WCME 2PMZH 4BBRE 4A3KE 3I4ME 3HOVE 5FJ8E 4A3GE 3GTJE 4A3IE 1R9TE 4A3LE 3S16E 3RZOE 4BXXE 2NVTE 1SFOE 1I6HE 2WB1H 4A3DE 3HOUE 4BBSE 3HKZH 5IYBE 1EIKA 3HOWE 2B63E 5IP7E 3S1RE 1I50E 1TWFE 4C3HE 3S1ME 5C4JE 3S14E 3S1QE 5IYDE 3S15E 3CQZE 1I3QE 5M5XE 3I4NE 3GTLE 5C44E 5M5WE 5IP9E 5M5YE 4A3EE 3GTQE 3M3YE 4C3JE 1TWAE 3GTGE 4C3IE 2E2JE 3H0GE 1DZFA 3S1NE 3GTKE 2E2HE 4AYBH 1Y1VE 4Y7NE 2VUME 3PO2E 4Y52E 1TWCE 2Y0SH 2R92E 4A3FE 4C2ME 4A3ME 4QIWH 3S17E 5IYCE 3K7AE 3GTOE 1K83E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H3V F;  4BY7 E;  5C4X E;  3PO3 E;  3HOY E;  3FKI E;  4A3J E;  3S2D E;  3M4O E;  5FLM E;  2JA5 E;  2NVY E;  2JA7 E;  1TWH E;  3GTM E;  3HOZ E;  1Y1W E;  2WAQ H;  4A93 E;  4A3C E;  3S2H E;  5M3F E;  4A3B E;  4BY1 E;  5M3M E;  2R93 E;  3RZD E;  2NVX E;  4X6A E;  1TWG E;  2NVQ E;  5C3E E;  2JA8 E;  2E2I E;  2YU9 E;  2R7Z E;  2JA6 E;  3GTP E;  3HOX E;  1WCM E;  2PMZ H;  4BBR E;  4A3K E;  3I4M E;  3HOV E;  5FJ8 E;  4A3G E;  3GTJ E;  4A3I E;  1R9T E;  4A3L E;  3S16 E;  3RZO E;  4BXX E;  2NVT E;  1SFO E;  1I6H E;  2WB1 H;  4A3D E;  3HOU E;  4BBS E;  3HKZ H;  5IYB E;  1EIK A;  3HOW E;  2B63 E;  5IP7 E;  3S1R E;  1I50 E;  1TWF E;  4C3H E;  3S1M E;  5C4J E;  3S14 E;  3S1Q E;  5IYD E;  3S15 E;  3CQZ E;  1I3Q E;  5M5X E;  3I4N E;  3GTL E;  5C44 E;  5M5W E;  5IP9 E;  5M5Y E;  4A3E E;  3GTQ E;  3M3Y E;  4C3J E;  1TWA E;  3GTG E;  4C3I E;  2E2J E;  3H0G E;  1DZF A;  3S1N E;  3GTK E;  2E2H E;  4AYB H;  1Y1V E;  4Y7N E;  2VUM E;  3PO2 E;  4Y52 E;  1TWC E;  2Y0S H;  2R92 E;  4A3F E;  4C2M E;  4A3M E;  4QIW H;  3S17 E;  5IYC E;  3K7A E;  3GTO E;  1K83 E; 
#chains in the Genus database with same CATH topology
 4XSX E;  3H3V F;  4BY7 E;  5C4X E;  4G7Z E;  3PO3 E;  3HOY E;  4KMU E;  3FKI E;  5IYD F;  3I4M F;  3S14 F;  4Q4Z E;  4A3J E;  3S2D E;  5FJ8 F;  3S1M F;  3M4O E;  4ZH4 E;  4MEX E;  3S15 F;  3CQZ F;  2WAQ K;  5FLM E;  2JA5 E;  2NVY E;  2JA7 E;  1I3Q F;  4MEY E;  4AYB K;  3GTJ F;  5E17 E;  4YFN E;  1R9T F;  1QKL A;  3I4N F;  4KN7 E;  1TWH E;  3GTM E;  3HOZ E;  4LK0 E;  1Y1W E;  3S16 F;  2WAQ H;  5C44 F;  5M5W F;  4A93 E;  5M5Y F;  1I6V E;  4A3E F;  4Q5S E;  3RZO F;  4OIR E;  4BXX F;  2NVT F;  4C3J F;  1TWA F;  1I6H F;  3GTG F;  4A3C E;  3S2H E;  4C3I F;  5M3F E;  2E2J F;  4A3B E;  4BY1 E;  1YNN K;  1ZYR E;  3HOU F;  5IYB F;  5M3M E;  2R93 E;  3HOW F;  4LLG E;  2A6H E;  3RZD E;  2B63 F;  2NVX E;  4X6A E;  1TWC F;  1TWF F;  3WOD E;  4C3H F;  1TWG E;  4YFK E;  2NVQ E;  4OIQ E;  4OIP E;  5C3E E;  2JA8 E;  2Y0S I;  4XLN E;  2E2I E;  3S1Q F;  4XSZ E;  4XLP E;  3S17 F;  2YU9 E;  2R7Z E;  2JA6 E;  2A69 E;  2PMZ K;  5C4X F;  5M5X F;  3HOY F;  4YFX E;  3FKI F;  3GTP E;  3HOX E;  3DXJ E;  3GTL F;  4A3J F;  4GZY E;  1WCM E;  3M4O F;  1IW7 E;  2A68 E;  5IP9 F;  4G7H E;  2PMZ H;  4BBR E;  4A3K E;  5FLM F;  2NVY F;  3GTQ F;  3M3Y F;  3I4M E;  4JK1 E;  3HOV E;  5FJ8 E;  1SMY E;  1TWH F;  2O5I E;  3H0G F;  1Y1W F;  1YNJ K;  5TMC E;  3S1N F;  3GTK F;  2E2H F;  1Y1V F;  4A3G E;  4YG2 E;  3GTJ E;  4A3I E;  5TMF E;  4Y7N F;  1R9T E;  2VUM F;  3PO2 F;  4A3L E;  4Y52 F;  3S2H F;  3S16 E;  5M3F F;  2R92 F;  4BY1 F;  4A3F F;  3RZO E;  4C2M F;  2KRX A;  4BXX E;  4A3M F;  5M3M F;  2R93 F;  2NVT E;  1SFO E;  2BE5 E;  3HKZ K;  1I6H E;  5IYC F;  3K7A F;  2NVX F;  2O5J E;  3GTO F;  1K83 F;  4A3D E;  2WB1 H;  4LK1 E;  1HQM E;  3HOU E;  4BBS E;  3HKZ H;  4BY7 F;  5IYB E;  2JA8 F;  3PO3 F;  1EIK A;  3HOW E;  2B63 E;  5IP7 E;  3S1R E;  2PPB E;  2YU9 F;  3S2D F;  1I50 E;  1TWF E;  4C3H E;  3S1M E;  5C4J E;  3H3V G;  2JA6 F;  5D4C E;  2JA5 F;  2JA7 F;  4G7O E;  3S14 E;  3S1Q E;  5IYD E;  3HOX F;  3GTM F;  3HOZ F;  2CW0 E;  3S15 E;  3CQZ E;  4A93 F;  4BBR F;  4A3K F;  1I3Q E;  5M5X E;  3EQL E;  3I4N E;  3GTL E;  2A6E E;  5BYH E;  3HOV F;  4A3C F;  5C44 E;  4A3B F;  5M5W E;  5IP9 E;  5M5Y E;  4A3E E;  3GTQ E;  4A3G F;  3M3Y E;  4A3I F;  4C3J E;  1TWA E;  3GTG E;  4LJZ E;  4C3I E;  3RZD F;  4A3L F;  2E2J E;  3H0G E;  4X6A F;  5D4E E;  1TWG F;  1DZF A;  3S1N E;  3GTK E;  2E2H E;  4AYB H;  1Y1V E;  5C3E F;  4OIO E;  2NVQ F;  4Y7N E;  2E2I F;  2VUM E;  3PO2 E;  4Y52 E;  1SFO F;  1TWC E;  4KN4 E;  4QIW K;  2Y0S H;  4MQ9 E;  2R7Z F;  2R92 E;  4A3D F;  4A3F E;  5D4D E;  4OIN E;  4C2M E;  4BBS F;  4A3M E;  2WB1 I;  4QIW H;  3GTP F;  3S17 E;  5IPL E;  5IYC E;  5IP7 F;  3K7A E;  3S1R F;  1WCM F;  1I50 F;  3GTO E;  1K83 E;  5E18 E;  5C4J F; 
#chains in the Genus database with same CATH homology
 3H3V F;  4BY7 E;  5C4X E;  3PO3 E;  3HOY E;  3FKI E;  4A3J E;  3S2D E;  3M4O E;  5FLM E;  2JA5 E;  2NVY E;  2JA7 E;  1TWH E;  3GTM E;  3HOZ E;  1Y1W E;  2WAQ H;  4A93 E;  4A3C E;  3S2H E;  5M3F E;  4A3B E;  4BY1 E;  5M3M E;  2R93 E;  3RZD E;  2NVX E;  4X6A E;  1TWG E;  2NVQ E;  5C3E E;  2JA8 E;  2E2I E;  2YU9 E;  2R7Z E;  2JA6 E;  3GTP E;  3HOX E;  1WCM E;  2PMZ H;  4BBR E;  4A3K E;  3I4M E;  3HOV E;  5FJ8 E;  4A3G E;  3GTJ E;  4A3I E;  1R9T E;  4A3L E;  3S16 E;  3RZO E;  4BXX E;  2NVT E;  1SFO E;  1I6H E;  2WB1 H;  4A3D E;  3HOU E;  4BBS E;  3HKZ H;  5IYB E;  1EIK A;  3HOW E;  2B63 E;  5IP7 E;  3S1R E;  1I50 E;  1TWF E;  4C3H E;  3S1M E;  5C4J E;  3S14 E;  3S1Q E;  5IYD E;  3S15 E;  3CQZ E;  1I3Q E;  5M5X E;  3I4N E;  3GTL E;  5C44 E;  5M5W E;  5IP9 E;  5M5Y E;  4A3E E;  3GTQ E;  3M3Y E;  4C3J E;  1TWA E;  3GTG E;  4C3I E;  2E2J E;  3H0G E;  1DZF A;  3S1N E;  3GTK E;  2E2H E;  4AYB H;  1Y1V E;  4Y7N E;  2VUM E;  3PO2 E;  4Y52 E;  1TWC E;  2Y0S H;  2R92 E;  4A3F E;  4C2M E;  4A3M E;  4QIW H;  3S17 E;  5IYC E;  3K7A E;  3GTO E;  1K83 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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