3S1NE

Rna polymerase ii initiation complex with a 5-nt rna (variant 2)
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 65
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s1nE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s1nE02
3S1RE 2WB1H 3HOZE 2PMZH 3I4ME 5C4JE 4Y52E 1I3QE 3S2HE 3H3VF 5C4XE 1TWCE 3RZDE 3PO2E 5IP9E 2E2JE 5IYDE 4A3IE 2YU9E 2R93E 4A3KE 4A3FE 2WAQH 3S17E 3S15E 3GTKE 4QIWH 4C3HE 4X6AE 3GTME 5C3EE 3S16E 2JA7E 5M5WE 2E2HE 4A3CE 3HOXE 5FJ8E 2B63E 2NVYE 5M5YE 4A93E 3H0GE 3GTGE 4A3LE 5IYBE 1Y1VE 1SFOE 4A3EE 2VUME 1I50E 3HOVE 2R92E 4A3BE 1WCME 1TWGE 3HOYE 2E2IE 2R7ZE 1TWFE 4C3JE 2Y0SH 3GTPE 3GTQE 3FKIE 1I6HE 3GTLE 3GTJE 4BY1E 3S1QE 4A3GE 1EIKA 4BBRE 5FLME 5M3ME 3HKZH 4AYBH 3HOWE 3K7AE 2NVXE 2JA8E 3PO3E 3S1NE 3I4NE 1DZFA 4BY7E 3S1ME 1Y1WE 1K83E 4C3IE 4A3JE 4A3ME 4C2ME 3S2DE 5M3FE 2JA5E 3HOUE 3M4OE 5C44E 1TWAE 4A3DE 3RZOE 4BBSE 2NVTE 3S14E 3GTOE 1TWHE 4Y7NE 5IYCE 5IP7E 3CQZE 4BXXE 5M5XE 2NVQE 3M3YE 2JA6E 1R9TE
chains in the Genus database with same CATH superfamily
3S1RE 2WB1H 4BY7F 3HOZE 2PMZH 3I4ME 3S1MF 4OIRE 1Y1WF 1HQME 4KN4E 5E17E 5C4JE 5TMFE 4Y52E 4C3IF 4A3JF 4A3MF 1I3QE 3S2HE 4C2MF 3H3VF 5C4XE 4OIOE 3S2DF 1TWCE 4KMUE 3RZDE 3PO2E 5IP9E 5M3FF 1I6HF 2JA5F 3HOUF 3M4OF 5C44F 4MEXE 1TWAF 2E2JE 2O5JE 5IYDE 4A3IE 2YU9E 2R93E 4A3KE 4BBRF 4A3FE 3RZOF 4A3DF 2A69E 2PMZK 5M3MF 4OIQE 4BBSF 2WAQH 2WB1I 2BE5E 3S17E 3H3VG 2NVTF 3S15E 3GTKE 4QIWH 2O5IE 3GTOF 1TWHF 4Y7NF 5IP7F 4C3HE 5IYCF 4X6AE 2A6EE 5D4DE 4BXXF 1ZYRE 5M5XF 3GTME 2NVQF 4LJZE 1K83F 2JA6F 4OINE 5C3EE 3S16E 4LK1E 3M3YF 3S1RF 2JA7E 5M5WE 2E2HE 4A3CE 4MEYE 3HOXE 3I4MF 5FJ8E 2WAQK 2B63E 2NVYE 5C4JF 3WODE 5M5YE 4A93E 3H0GE 1I3QF 3S2HF 1YNJK 4QIWK 3GTGE 4A3LE 1TWCF 3RZDF 5IYBE 3PO2F 5IP9F 1Y1VE 1SFOE 4A3EE 4XSXE 2VUME 4Q5SE 5D4CE 1I50E 3HOVE 2R92E 1IW7E 4ZH4E 4A3BE 5TMCE 4YFNE 1WCME 1TWGE 3HOYE 5IYDF 4A3IF 2E2JF 5IPLE 2YU9F 2R93F 2E2IE 4G7ZE 2R7ZE 4A3KF 4A3FF 3S14F 1TWFE 4MQ9E 4C3JE 2Y0SH 3GTPE 3S17F 3GTQE 3FKIE 3GTKF 1I6HE 3CQZF 3GTLE 3GTJE 4BY1E 3S1QE 1R9TF 4X6AF 4A3GE 3HOZF 3GTMF 4BBRE 1EIKA 5FLME 4JK1E 4LLGE 5M3ME 5C3EF 2PPBE 1I6VE 4XSZE 4Y52F 5M5WF 2E2HF 3HKZH 4AYBH 3HOXF 4A3CF 5FJ8F 5C4XF 2B63F 2NVYF 3HOWE 1QKLA 5M5YF 4A93F 3K7AE 2NVXE 2JA8E 3PO3E 2CW0E 3S1NE 2Y0SI 3GTGF 4A3LF 5E18E 3I4NE 4KN7E 5IYBF 1DZFA 1Y1VF 1SFOF 4A3EF 4YG2E 4BY7E 2VUMF 1I50F 3EQLE 3HOVF 4YFXE 2R92F 3S1ME 1Y1WE 1K83E 4A3BF 1WCMF 3HOYF 4C3IE 4A3JE 4A3ME 4C2ME 3S2DE 4OIPE 2E2IF 2R7ZF 4G7OE 3S15F 1TWFF 3HKZK 4AYBK 5M3FE 2A68E 4C3JF 2JA5E 3HOUE 3M4OE 3GTPF 5C44E 3GTQF 1TWAE 3FKIF 4G7HE 4C3HF 2KRXA 1SMYE 4YFKE 3GTLF 4A3DE 3RZOE 1YNNK 4XLPE 3GTJF 4BY1F 3S16F 3S1QF 4XLNE 4BBSE 4LK0E 2JA7F 4A3GF 5FLMF 2NVTE 3S14E 2A6HE 5BYHE 3GTOE 3H0GF 5D4EE 1TWHE 4Y7NE 5IYCE 5IP7E 3HOWF 3CQZE 3DXJE 3K7AF 4BXXE 2NVXF 5M5XE 2JA8F 2NVQE 4Q4ZE 3PO3F 3S1NF 4GZYE 3I4NF 3M3YE 2JA6E 1TWGF 1R9TE
chains in the Genus database with same CATH topology
3S1RE 2WB1H 3HOZE 2PMZH 3I4ME 5C4JE 4Y52E 1I3QE 3S2HE 3H3VF 5C4XE 1TWCE 3RZDE 3PO2E 5IP9E 2E2JE 5IYDE 4A3IE 2YU9E 2R93E 4A3KE 4A3FE 2WAQH 3S17E 3S15E 3GTKE 4QIWH 4C3HE 4X6AE 3GTME 5C3EE 3S16E 2JA7E 5M5WE 2E2HE 4A3CE 3HOXE 5FJ8E 2B63E 2NVYE 5M5YE 4A93E 3H0GE 3GTGE 4A3LE 5IYBE 1Y1VE 1SFOE 4A3EE 2VUME 1I50E 3HOVE 2R92E 4A3BE 1WCME 1TWGE 3HOYE 2E2IE 2R7ZE 1TWFE 4C3JE 2Y0SH 3GTPE 3GTQE 3FKIE 1I6HE 3GTLE 3GTJE 4BY1E 3S1QE 4A3GE 1EIKA 4BBRE 5FLME 5M3ME 3HKZH 4AYBH 3HOWE 3K7AE 2NVXE 2JA8E 3PO3E 3S1NE 3I4NE 1DZFA 4BY7E 3S1ME 1Y1WE 1K83E 4C3IE 4A3JE 4A3ME 4C2ME 3S2DE 5M3FE 2JA5E 3HOUE 3M4OE 5C44E 1TWAE 4A3DE 3RZOE 4BBSE 2NVTE 3S14E 3GTOE 1TWHE 4Y7NE 5IYCE 5IP7E 3CQZE 4BXXE 5M5XE 2NVQE 3M3YE 2JA6E 1R9TE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1R E;  2WB1 H;  3HOZ E;  2PMZ H;  3I4M E;  5C4J E;  4Y52 E;  1I3Q E;  3S2H E;  3H3V F;  5C4X E;  1TWC E;  3RZD E;  3PO2 E;  5IP9 E;  2E2J E;  5IYD E;  4A3I E;  2YU9 E;  2R93 E;  4A3K E;  4A3F E;  2WAQ H;  3S17 E;  3S15 E;  3GTK E;  4QIW H;  4C3H E;  4X6A E;  3GTM E;  5C3E E;  3S16 E;  2JA7 E;  5M5W E;  2E2H E;  4A3C E;  3HOX E;  5FJ8 E;  2B63 E;  2NVY E;  5M5Y E;  4A93 E;  3H0G E;  3GTG E;  4A3L E;  5IYB E;  1Y1V E;  1SFO E;  4A3E E;  2VUM E;  1I50 E;  3HOV E;  2R92 E;  4A3B E;  1WCM E;  1TWG E;  3HOY E;  2E2I E;  2R7Z E;  1TWF E;  4C3J E;  2Y0S H;  3GTP E;  3GTQ E;  3FKI E;  1I6H E;  3GTL E;  3GTJ E;  4BY1 E;  3S1Q E;  4A3G E;  1EIK A;  4BBR E;  5FLM E;  5M3M E;  3HKZ H;  4AYB H;  3HOW E;  3K7A E;  2NVX E;  2JA8 E;  3PO3 E;  3S1N E;  3I4N E;  1DZF A;  4BY7 E;  3S1M E;  1Y1W E;  1K83 E;  4C3I E;  4A3J E;  4A3M E;  4C2M E;  3S2D E;  5M3F E;  2JA5 E;  3HOU E;  3M4O E;  5C44 E;  1TWA E;  4A3D E;  3RZO E;  4BBS E;  2NVT E;  3S14 E;  3GTO E;  1TWH E;  4Y7N E;  5IYC E;  5IP7 E;  3CQZ E;  4BXX E;  5M5X E;  2NVQ E;  3M3Y E;  2JA6 E;  1R9T E; 
#chains in the Genus database with same CATH topology
 3S1R E;  2WB1 H;  4BY7 F;  3HOZ E;  2PMZ H;  3I4M E;  3S1M F;  4OIR E;  1Y1W F;  1HQM E;  4KN4 E;  5E17 E;  5C4J E;  5TMF E;  4Y52 E;  4C3I F;  4A3J F;  4A3M F;  1I3Q E;  3S2H E;  4C2M F;  3H3V F;  5C4X E;  4OIO E;  3S2D F;  1TWC E;  4KMU E;  3RZD E;  3PO2 E;  5IP9 E;  5M3F F;  1I6H F;  2JA5 F;  3HOU F;  3M4O F;  5C44 F;  4MEX E;  1TWA F;  2E2J E;  2O5J E;  5IYD E;  4A3I E;  2YU9 E;  2R93 E;  4A3K E;  4BBR F;  4A3F E;  3RZO F;  4A3D F;  2A69 E;  2PMZ K;  5M3M F;  4OIQ E;  4BBS F;  2WAQ H;  2WB1 I;  2BE5 E;  3S17 E;  3H3V G;  2NVT F;  3S15 E;  3GTK E;  4QIW H;  2O5I E;  3GTO F;  1TWH F;  4Y7N F;  5IP7 F;  4C3H E;  5IYC F;  4X6A E;  2A6E E;  5D4D E;  4BXX F;  1ZYR E;  5M5X F;  3GTM E;  2NVQ F;  4LJZ E;  1K83 F;  2JA6 F;  4OIN E;  5C3E E;  3S16 E;  4LK1 E;  3M3Y F;  3S1R F;  2JA7 E;  5M5W E;  2E2H E;  4A3C E;  4MEY E;  3HOX E;  3I4M F;  5FJ8 E;  2WAQ K;  2B63 E;  2NVY E;  5C4J F;  3WOD E;  5M5Y E;  4A93 E;  3H0G E;  1I3Q F;  3S2H F;  1YNJ K;  4QIW K;  3GTG E;  4A3L E;  1TWC F;  3RZD F;  5IYB E;  3PO2 F;  5IP9 F;  1Y1V E;  1SFO E;  4A3E E;  4XSX E;  2VUM E;  4Q5S E;  5D4C E;  1I50 E;  3HOV E;  2R92 E;  1IW7 E;  4ZH4 E;  4A3B E;  5TMC E;  4YFN E;  1WCM E;  1TWG E;  3HOY E;  5IYD F;  4A3I F;  2E2J F;  5IPL E;  2YU9 F;  2R93 F;  2E2I E;  4G7Z E;  2R7Z E;  4A3K F;  4A3F F;  3S14 F;  1TWF E;  4MQ9 E;  4C3J E;  2Y0S H;  3GTP E;  3S17 F;  3GTQ E;  3FKI E;  3GTK F;  1I6H E;  3CQZ F;  3GTL E;  3GTJ E;  4BY1 E;  3S1Q E;  1R9T F;  4X6A F;  4A3G E;  3HOZ F;  3GTM F;  4BBR E;  1EIK A;  5FLM E;  4JK1 E;  4LLG E;  5M3M E;  5C3E F;  2PPB E;  1I6V E;  4XSZ E;  4Y52 F;  5M5W F;  2E2H F;  3HKZ H;  4AYB H;  3HOX F;  4A3C F;  5FJ8 F;  5C4X F;  2B63 F;  2NVY F;  3HOW E;  1QKL A;  5M5Y F;  4A93 F;  3K7A E;  2NVX E;  2JA8 E;  3PO3 E;  2CW0 E;  3S1N E;  2Y0S I;  3GTG F;  4A3L F;  5E18 E;  3I4N E;  4KN7 E;  5IYB F;  1DZF A;  1Y1V F;  1SFO F;  4A3E F;  4YG2 E;  4BY7 E;  2VUM F;  1I50 F;  3EQL E;  3HOV F;  4YFX E;  2R92 F;  3S1M E;  1Y1W E;  1K83 E;  4A3B F;  1WCM F;  3HOY F;  4C3I E;  4A3J E;  4A3M E;  4C2M E;  3S2D E;  4OIP E;  2E2I F;  2R7Z F;  4G7O E;  3S15 F;  1TWF F;  3HKZ K;  4AYB K;  5M3F E;  2A68 E;  4C3J F;  2JA5 E;  3HOU E;  3M4O E;  3GTP F;  5C44 E;  3GTQ F;  1TWA E;  3FKI F;  4G7H E;  4C3H F;  2KRX A;  1SMY E;  4YFK E;  3GTL F;  4A3D E;  3RZO E;  1YNN K;  4XLP E;  3GTJ F;  4BY1 F;  3S16 F;  3S1Q F;  4XLN E;  4BBS E;  4LK0 E;  2JA7 F;  4A3G F;  5FLM F;  2NVT E;  3S14 E;  2A6H E;  5BYH E;  3GTO E;  3H0G F;  5D4E E;  1TWH E;  4Y7N E;  5IYC E;  5IP7 E;  3HOW F;  3CQZ E;  3DXJ E;  3K7A F;  4BXX E;  2NVX F;  5M5X E;  2JA8 F;  2NVQ E;  4Q4Z E;  3PO3 F;  3S1N F;  4GZY E;  3I4N F;  3M3Y E;  2JA6 E;  1TWG F;  1R9T E; 
#chains in the Genus database with same CATH homology
 3S1R E;  2WB1 H;  3HOZ E;  2PMZ H;  3I4M E;  5C4J E;  4Y52 E;  1I3Q E;  3S2H E;  3H3V F;  5C4X E;  1TWC E;  3RZD E;  3PO2 E;  5IP9 E;  2E2J E;  5IYD E;  4A3I E;  2YU9 E;  2R93 E;  4A3K E;  4A3F E;  2WAQ H;  3S17 E;  3S15 E;  3GTK E;  4QIW H;  4C3H E;  4X6A E;  3GTM E;  5C3E E;  3S16 E;  2JA7 E;  5M5W E;  2E2H E;  4A3C E;  3HOX E;  5FJ8 E;  2B63 E;  2NVY E;  5M5Y E;  4A93 E;  3H0G E;  3GTG E;  4A3L E;  5IYB E;  1Y1V E;  1SFO E;  4A3E E;  2VUM E;  1I50 E;  3HOV E;  2R92 E;  4A3B E;  1WCM E;  1TWG E;  3HOY E;  2E2I E;  2R7Z E;  1TWF E;  4C3J E;  2Y0S H;  3GTP E;  3GTQ E;  3FKI E;  1I6H E;  3GTL E;  3GTJ E;  4BY1 E;  3S1Q E;  4A3G E;  1EIK A;  4BBR E;  5FLM E;  5M3M E;  3HKZ H;  4AYB H;  3HOW E;  3K7A E;  2NVX E;  2JA8 E;  3PO3 E;  3S1N E;  3I4N E;  1DZF A;  4BY7 E;  3S1M E;  1Y1W E;  1K83 E;  4C3I E;  4A3J E;  4A3M E;  4C2M E;  3S2D E;  5M3F E;  2JA5 E;  3HOU E;  3M4O E;  5C44 E;  1TWA E;  4A3D E;  3RZO E;  4BBS E;  2NVT E;  3S14 E;  3GTO E;  1TWH E;  4Y7N E;  5IYC E;  5IP7 E;  3CQZ E;  4BXX E;  5M5X E;  2NVQ E;  3M3Y E;  2JA6 E;  1R9T E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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