3S1RF

Rna polymerase ii initiation complex with a 5-nt 3'-deoxy rna soaked with gtp
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
85
structure length
85
Chain Sequence
EKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 24
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 3s1rF00
1IW7E 3CQZF 4A3KF 4OIQE 4KN7E 1Y1VF 5M3FF 4C2MF 3GTOF 4A93F 4Y52F 2E2IF 3HOUF 1YNNK 3GTGF 3GTPF 3PO2F 3DXJE 2CW0E 3HKZK 3S1MF 4G7OE 3GTKF 5FJ8F 5M5WF 3S2HF 2PMZK 4KN4E 4YFXE 4XSXE 4G7ZE 3M3YF 1I6HF 4ZH4E 5IYDF 4BY1F 4XSZE 4MQ9E 3HOWF 5M5XF 3RZOF 2A68E 5IYCF 2O5IE 2WB1I 1SMYE 3S15F 1I6VE 3HOXF 4OIOE 5D4CE 2YU9F 4OIRE 4LK1E 2NVXF 2E2JF 3S16F 1K83F 4MEYE 2BE5E 1Y1WF 2B63F 1HQME 1TWGF 4Q4ZE 4BXXF 3RZDF 3M4OF 4YFKE 1ZYRE 3H0GF 3S1QF 4LK0E 1R9TF 3PO3F 5IP9F 4BBRF 4A3LF 2VUMF 2O5JE 3S1RF 5C4JF 3HOYF 1SFOF 4C3HF 4LLGE 4YFNE 4MEXE 3GTMF 4C3JF 3GTQF 1TWFF 4A3BF 2Y0SI 4YG2E 4A3IF 3FKIF 5M3MF 3S14F 2JA8F 1TWHF 1TWCF 4Q5SE 2A69E 4A3EF 2R7ZF 5IP7F 4KMUE 3GTJF 2JA6F 4GZYE 1TWAF 3EQLE 3S1NF 1I50F 5TMFE 2R92F 2JA7F 4G7HE 2A6HE 5TMCE 1QKLA 1WCMF 4BY7F 3WODE 2NVQF 5IYBF 2A6EE 4OIPE 3HOVF 5E17E 4A3MF 5D4DE 5M5YF 4X6AF 4JK1E 5C4XF 5BYHE 4XLNE 1I3QF 2NVTF 3GTLF 4A3CF 3H3VG 5C44F 5E18E 3I4MF 4BBSF 4AYBK 4XLPE 4A3GF 2PPBE 2JA5F 2R93F 5D4EE 4Y7NF 5FLMF 4A3JF 2E2HF 3K7AF 4C3IF 2NVYF 4LJZE 5C3EF 3S17F 5IPLE 3S2DF 4OINE 4A3DF 3I4NF 4A3FF 1YNJK 2WAQK 3HOZF
chains in the Genus database with same CATH superfamily
1IW7E 3CQZF 4C2ME 3HOXE 4A3KF 4OIQE 2E2IE 4KN7E 3GTOE 1Y1VF 4Y52E 4AYBH 4C2MF 5M3FF 3GTOF 4A93F 4Y52F 2E2IF 3HOUF 3PO2E 2NVXE 3S1ME 1YNNK 2E2JE 3GTKE 3GTGF 3GTPF 3S16E 3PO2F 3DXJE 2CW0E 3HKZK 3S1MF 4G7OE 3GTKF 1Y1WE 5FJ8F 5M5WF 1TWGE 3S2HF 2PMZK 2Y0SH 3M4OE 4KN4E 4BXXE 3S1QE 4YFXE 4XSXE 1I6HE 5IP9E 4G7ZE 2KRXA 4BY1E 1I6HF 3M3YF 3HOWE 4ZH4E 5M5XE 5IYDF 4BY1F 4XSZE 4MQ9E 3HOWF 3RZOE 5M5XF 3GTME 4C3JE 3RZOF 4A3BE 2A68E 5IYCF 4A3IE 3FKIE 5M3ME 2O5IE 3HKZH 2WB1I 1SMYE 3S14E 3S15F 2JA8E 1TWHE 2PMZH 1I6VE 3HOXF 2YU9E 5IP7E 3GTJE 5D4CE 4OIOE 3S1NE 2YU9F 1K83E 4OIRE 4LK1E 2NVXF 2JA7E 2E2JF 3S16F 1K83F 4MEYE 2B63E 2BE5E 1WCME 1Y1WF 2B63F 1HQME 3RZDE 2NVQE 1TWGF 3H0GE 1DZFA 4Q4ZE 4BXXF 3RZDF 3M4OF 4YFKE 1R9TE 1ZYRE 3H0GF 3PO3E 3S1QF 4BBRE 2WAQH 4A3LE 2VUME 4LK0E 1R9TF 3PO3F 5IP9F 4BBRF 4A3LF 2VUMF 2O5JE 3S1RE 5C4JE 3HOYE 1SFOE 4C3HE 4QIWK 3S1RF 5C4JF 3GTQE 1TWFE 4C3HF 1SFOF 4LLGE 4YFNE 4MEXE 3HOYF 3GTMF 4C3JF 3GTQF 1TWFF 4A3BF 2Y0SI 4YG2E 5C4XE 4A3IF 3FKIF 5M3MF 2NVTE 3GTLE 1TWCE 5C44E 4BBSE 3S14F 3I4ME 4A3EE 1TWHF 2JA8F 2R7ZE 1TWCF 2JA6E 1TWAE 4Q5SE 2A69E 4A3EF 2R7ZF 3H3VF 1I50E 4KMUE 5IP7F 3GTJF 2JA6F 1TWAF 3EQLE 3S1NF 4GZYE 2R92E 1I50F 5TMFE 2R92F 2JA5E 2JA7F 4G7HE 2R93E 4BY7E 2A6HE 5TMCE 5FLME 2E2HE 1QKLA 1WCMF 5IYBE 4C3IE 2NVYE 4BY7F 5C3EE 3S17E 3S2DE 3WODE 2NVQF 5IYBF 3HOVE 2A6EE 4OIPE 3HOZE 3HOVF 5E17E 4A3ME 3CQZE 4A3MF 5M5YE 5M3FE 4A93E 3HOUE 5D4DE 5M5YF 4X6AE 3GTGE 3GTPE 1EIKA 1I3QE 4X6AF 5FJ8E 4JK1E 5C4XF 5M5WE 5BYHE 3S2HE 4XLNE 1I3QF 2NVTF 4A3CE 3GTLF 4A3CF 3H3VG 5C44F 5E18E 3I4MF 4BBSF 2WB1H 4AYBK 4A3GE 4XLPE 4A3GF 2PPBE 3M3YE 4Y7NE 4A3JE 5IYDE 2JA5F 3K7AE 2R93F 5D4EE 4Y7NF 5FLMF 4QIWH 4A3JF 2E2HF 3K7AF 4C3IF 2NVYF 4LJZE 5C3EF 5IYCE 4A3FE 3I4NE 3S17F 3S2DF 4A3DE 5IPLE 4OINE 4A3DF 3I4NF 4A3FF 1YNJK 2WAQK 3HOZF 4A3KE 3S15E 1Y1VE
chains in the Genus database with same CATH topology
1IW7E 3CQZF 4A3KF 4OIQE 4KN7E 1Y1VF 5M3FF 4C2MF 3GTOF 4A93F 4Y52F 2E2IF 3HOUF 1YNNK 3GTGF 3GTPF 3PO2F 3DXJE 2CW0E 3HKZK 3S1MF 4G7OE 3GTKF 5FJ8F 5M5WF 3S2HF 2PMZK 4KN4E 4YFXE 4XSXE 4G7ZE 2KRXA 3M3YF 1I6HF 4ZH4E 5IYDF 4BY1F 4XSZE 4MQ9E 3HOWF 5M5XF 3RZOF 2A68E 5IYCF 2O5IE 2WB1I 1SMYE 3S15F 1I6VE 3HOXF 4OIOE 5D4CE 2YU9F 4OIRE 4LK1E 2NVXF 2E2JF 3S16F 1K83F 4MEYE 2BE5E 1Y1WF 2B63F 1HQME 1TWGF 4Q4ZE 4BXXF 3RZDF 3M4OF 4YFKE 1ZYRE 3H0GF 3S1QF 4LK0E 1R9TF 3PO3F 5IP9F 4BBRF 4A3LF 2VUMF 2O5JE 4QIWK 3S1RF 5C4JF 3HOYF 1SFOF 4C3HF 4LLGE 4YFNE 4MEXE 3GTMF 4C3JF 3GTQF 1TWFF 4A3BF 2Y0SI 4YG2E 4A3IF 3FKIF 5M3MF 3S14F 2JA8F 1TWHF 1TWCF 4Q5SE 2A69E 4A3EF 2R7ZF 5IP7F 4KMUE 3GTJF 2JA6F 4GZYE 1TWAF 3EQLE 3S1NF 1I50F 5TMFE 2R92F 2JA7F 4G7HE 2A6HE 5TMCE 1QKLA 1WCMF 4BY7F 3WODE 2NVQF 5IYBF 2A6EE 4OIPE 3HOVF 5E17E 4A3MF 5D4DE 5M5YF 4X6AF 4JK1E 5C4XF 5BYHE 4XLNE 1I3QF 2NVTF 3GTLF 4A3CF 3H3VG 5C44F 5E18E 3I4MF 4BBSF 4AYBK 4XLPE 4A3GF 2PPBE 2JA5F 2R93F 5D4EE 4Y7NF 5FLMF 4A3JF 2E2HF 3K7AF 4C3IF 2NVYF 4LJZE 5C3EF 3S17F 5IPLE 3S2DF 4OINE 4A3DF 3I4NF 4A3FF 1YNJK 2WAQK 3HOZF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IW7 E;  3CQZ F;  4A3K F;  4OIQ E;  4KN7 E;  1Y1V F;  5M3F F;  4C2M F;  3GTO F;  4A93 F;  4Y52 F;  2E2I F;  3HOU F;  1YNN K;  3GTG F;  3GTP F;  3PO2 F;  3DXJ E;  2CW0 E;  3HKZ K;  3S1M F;  4G7O E;  3GTK F;  5FJ8 F;  5M5W F;  3S2H F;  2PMZ K;  4KN4 E;  4YFX E;  4XSX E;  4G7Z E;  3M3Y F;  1I6H F;  4ZH4 E;  5IYD F;  4BY1 F;  4XSZ E;  4MQ9 E;  3HOW F;  5M5X F;  3RZO F;  2A68 E;  5IYC F;  2O5I E;  2WB1 I;  1SMY E;  3S15 F;  1I6V E;  3HOX F;  4OIO E;  5D4C E;  2YU9 F;  4OIR E;  4LK1 E;  2NVX F;  2E2J F;  3S16 F;  1K83 F;  4MEY E;  2BE5 E;  1Y1W F;  2B63 F;  1HQM E;  1TWG F;  4Q4Z E;  4BXX F;  3RZD F;  3M4O F;  4YFK E;  1ZYR E;  3H0G F;  3S1Q F;  4LK0 E;  1R9T F;  3PO3 F;  5IP9 F;  4BBR F;  4A3L F;  2VUM F;  2O5J E;  3S1R F;  5C4J F;  3HOY F;  1SFO F;  4C3H F;  4LLG E;  4YFN E;  4MEX E;  3GTM F;  4C3J F;  3GTQ F;  1TWF F;  4A3B F;  2Y0S I;  4YG2 E;  4A3I F;  3FKI F;  5M3M F;  3S14 F;  2JA8 F;  1TWH F;  1TWC F;  4Q5S E;  2A69 E;  4A3E F;  2R7Z F;  5IP7 F;  4KMU E;  3GTJ F;  2JA6 F;  4GZY E;  1TWA F;  3EQL E;  3S1N F;  1I50 F;  5TMF E;  2R92 F;  2JA7 F;  4G7H E;  2A6H E;  5TMC E;  1QKL A;  1WCM F;  4BY7 F;  3WOD E;  2NVQ F;  5IYB F;  2A6E E;  4OIP E;  3HOV F;  5E17 E;  4A3M F;  5D4D E;  5M5Y F;  4X6A F;  4JK1 E;  5C4X F;  5BYH E;  4XLN E;  1I3Q F;  2NVT F;  3GTL F;  4A3C F;  3H3V G;  5C44 F;  5E18 E;  3I4M F;  4BBS F;  4AYB K;  4XLP E;  4A3G F;  2PPB E;  2JA5 F;  2R93 F;  5D4E E;  4Y7N F;  5FLM F;  4A3J F;  2E2H F;  3K7A F;  4C3I F;  2NVY F;  4LJZ E;  5C3E F;  3S17 F;  5IPL E;  3S2D F;  4OIN E;  4A3D F;  3I4N F;  4A3F F;  1YNJ K;  2WAQ K;  3HOZ F; 
#chains in the Genus database with same CATH topology
 1IW7 E;  3CQZ F;  4C2M E;  3HOX E;  4A3K F;  4OIQ E;  2E2I E;  4KN7 E;  3GTO E;  1Y1V F;  4Y52 E;  4AYB H;  4C2M F;  5M3F F;  3GTO F;  4A93 F;  4Y52 F;  2E2I F;  3HOU F;  3PO2 E;  2NVX E;  3S1M E;  1YNN K;  2E2J E;  3GTK E;  3GTG F;  3GTP F;  3S16 E;  3PO2 F;  3DXJ E;  2CW0 E;  3HKZ K;  3S1M F;  4G7O E;  3GTK F;  1Y1W E;  5FJ8 F;  5M5W F;  1TWG E;  3S2H F;  2PMZ K;  2Y0S H;  3M4O E;  4KN4 E;  4BXX E;  3S1Q E;  4YFX E;  4XSX E;  1I6H E;  5IP9 E;  4G7Z E;  2KRX A;  4BY1 E;  1I6H F;  3M3Y F;  3HOW E;  4ZH4 E;  5M5X E;  5IYD F;  4BY1 F;  4XSZ E;  4MQ9 E;  3HOW F;  3RZO E;  5M5X F;  3GTM E;  4C3J E;  3RZO F;  4A3B E;  2A68 E;  5IYC F;  4A3I E;  3FKI E;  5M3M E;  2O5I E;  3HKZ H;  2WB1 I;  1SMY E;  3S14 E;  3S15 F;  2JA8 E;  1TWH E;  2PMZ H;  1I6V E;  3HOX F;  2YU9 E;  5IP7 E;  3GTJ E;  5D4C E;  4OIO E;  3S1N E;  2YU9 F;  1K83 E;  4OIR E;  4LK1 E;  2NVX F;  2JA7 E;  2E2J F;  3S16 F;  1K83 F;  4MEY E;  2B63 E;  2BE5 E;  1WCM E;  1Y1W F;  2B63 F;  1HQM E;  3RZD E;  2NVQ E;  1TWG F;  3H0G E;  1DZF A;  4Q4Z E;  4BXX F;  3RZD F;  3M4O F;  4YFK E;  1R9T E;  1ZYR E;  3H0G F;  3PO3 E;  3S1Q F;  4BBR E;  2WAQ H;  4A3L E;  2VUM E;  4LK0 E;  1R9T F;  3PO3 F;  5IP9 F;  4BBR F;  4A3L F;  2VUM F;  2O5J E;  3S1R E;  5C4J E;  3HOY E;  1SFO E;  4C3H E;  4QIW K;  3S1R F;  5C4J F;  3GTQ E;  1TWF E;  4C3H F;  1SFO F;  4LLG E;  4YFN E;  4MEX E;  3HOY F;  3GTM F;  4C3J F;  3GTQ F;  1TWF F;  4A3B F;  2Y0S I;  4YG2 E;  5C4X E;  4A3I F;  3FKI F;  5M3M F;  2NVT E;  3GTL E;  1TWC E;  5C44 E;  4BBS E;  3S14 F;  3I4M E;  4A3E E;  1TWH F;  2JA8 F;  2R7Z E;  1TWC F;  2JA6 E;  1TWA E;  4Q5S E;  2A69 E;  4A3E F;  2R7Z F;  3H3V F;  1I50 E;  4KMU E;  5IP7 F;  3GTJ F;  2JA6 F;  1TWA F;  3EQL E;  3S1N F;  4GZY E;  2R92 E;  1I50 F;  5TMF E;  2R92 F;  2JA5 E;  2JA7 F;  4G7H E;  2R93 E;  4BY7 E;  2A6H E;  5TMC E;  5FLM E;  2E2H E;  1QKL A;  1WCM F;  5IYB E;  4C3I E;  2NVY E;  4BY7 F;  5C3E E;  3S17 E;  3S2D E;  3WOD E;  2NVQ F;  5IYB F;  3HOV E;  2A6E E;  4OIP E;  3HOZ E;  3HOV F;  5E17 E;  4A3M E;  3CQZ E;  4A3M F;  5M5Y E;  5M3F E;  4A93 E;  3HOU E;  5D4D E;  5M5Y F;  4X6A E;  3GTG E;  3GTP E;  1EIK A;  1I3Q E;  4X6A F;  5FJ8 E;  4JK1 E;  5C4X F;  5M5W E;  5BYH E;  3S2H E;  4XLN E;  1I3Q F;  2NVT F;  4A3C E;  3GTL F;  4A3C F;  3H3V G;  5C44 F;  5E18 E;  3I4M F;  4BBS F;  2WB1 H;  4AYB K;  4A3G E;  4XLP E;  4A3G F;  2PPB E;  3M3Y E;  4Y7N E;  4A3J E;  5IYD E;  2JA5 F;  3K7A E;  2R93 F;  5D4E E;  4Y7N F;  5FLM F;  4QIW H;  4A3J F;  2E2H F;  3K7A F;  4C3I F;  2NVY F;  4LJZ E;  5C3E F;  5IYC E;  4A3F E;  3I4N E;  3S17 F;  3S2D F;  4A3D E;  5IPL E;  4OIN E;  4A3D F;  3I4N F;  4A3F F;  1YNJ K;  2WAQ K;  3HOZ F;  4A3K E;  3S15 E;  1Y1V E; 
#chains in the Genus database with same CATH homology
 1IW7 E;  3CQZ F;  4A3K F;  4OIQ E;  4KN7 E;  1Y1V F;  5M3F F;  4C2M F;  3GTO F;  4A93 F;  4Y52 F;  2E2I F;  3HOU F;  1YNN K;  3GTG F;  3GTP F;  3PO2 F;  3DXJ E;  2CW0 E;  3HKZ K;  3S1M F;  4G7O E;  3GTK F;  5FJ8 F;  5M5W F;  3S2H F;  2PMZ K;  4KN4 E;  4YFX E;  4XSX E;  4G7Z E;  2KRX A;  3M3Y F;  1I6H F;  4ZH4 E;  5IYD F;  4BY1 F;  4XSZ E;  4MQ9 E;  3HOW F;  5M5X F;  3RZO F;  2A68 E;  5IYC F;  2O5I E;  2WB1 I;  1SMY E;  3S15 F;  1I6V E;  3HOX F;  4OIO E;  5D4C E;  2YU9 F;  4OIR E;  4LK1 E;  2NVX F;  2E2J F;  3S16 F;  1K83 F;  4MEY E;  2BE5 E;  1Y1W F;  2B63 F;  1HQM E;  1TWG F;  4Q4Z E;  4BXX F;  3RZD F;  3M4O F;  4YFK E;  1ZYR E;  3H0G F;  3S1Q F;  4LK0 E;  1R9T F;  3PO3 F;  5IP9 F;  4BBR F;  4A3L F;  2VUM F;  2O5J E;  4QIW K;  3S1R F;  5C4J F;  3HOY F;  1SFO F;  4C3H F;  4LLG E;  4YFN E;  4MEX E;  3GTM F;  4C3J F;  3GTQ F;  1TWF F;  4A3B F;  2Y0S I;  4YG2 E;  4A3I F;  3FKI F;  5M3M F;  3S14 F;  2JA8 F;  1TWH F;  1TWC F;  4Q5S E;  2A69 E;  4A3E F;  2R7Z F;  5IP7 F;  4KMU E;  3GTJ F;  2JA6 F;  4GZY E;  1TWA F;  3EQL E;  3S1N F;  1I50 F;  5TMF E;  2R92 F;  2JA7 F;  4G7H E;  2A6H E;  5TMC E;  1QKL A;  1WCM F;  4BY7 F;  3WOD E;  2NVQ F;  5IYB F;  2A6E E;  4OIP E;  3HOV F;  5E17 E;  4A3M F;  5D4D E;  5M5Y F;  4X6A F;  4JK1 E;  5C4X F;  5BYH E;  4XLN E;  1I3Q F;  2NVT F;  3GTL F;  4A3C F;  3H3V G;  5C44 F;  5E18 E;  3I4M F;  4BBS F;  4AYB K;  4XLP E;  4A3G F;  2PPB E;  2JA5 F;  2R93 F;  5D4E E;  4Y7N F;  5FLM F;  4A3J F;  2E2H F;  3K7A F;  4C3I F;  2NVY F;  4LJZ E;  5C3E F;  3S17 F;  5IPL E;  3S2D F;  4OIN E;  4A3D F;  3I4N F;  4A3F F;  1YNJ K;  2WAQ K;  3HOZ F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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