3S2DF

Rna polymerase ii initiation complex with a 5-nt rna containing a 5br-u
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
85
structure length
85
Chain Sequence
EKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 23
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 3s2dF00
1I3QF 4A3JF 3CQZF 1TWFF 1TWAF 4Q5SE 4MEXE 4XLPE 4A3MF 4A93F 3H0GF 1TWGF 5M3FF 5D4DE 3HOYF 3S1QF 3GTJF 2NVTF 4C2MF 1Y1WF 5D4CE 3PO3F 4A3CF 1ZYRE 5FLMF 3GTOF 5BYHE 2R93F 2JA7F 1YNNK 4MQ9E 5IPLE 1SFOF 4YG2E 4C3IF 4XSZE 2E2HF 4A3DF 4Q4ZE 4KMUE 4YFKE 4A3FF 4OIOE 4BBRF 2R7ZF 3GTLF 3M4OF 5C3EF 1HQME 3HOWF 4XSXE 3S2DF 4C3JF 2YU9F 4Y7NF 3HOVF 3PO2F 4ZH4E 5TMFE 5D4EE 2JA5F 5M5XF 4BXXF 2A68E 3GTQF 1I6VE 5IYBF 2R92F 3S14F 1SMYE 4XLNE 2E2IF 4LK0E 4G7ZE 3GTMF 2JA6F 4OIRE 5C44F 1R9TF 3H3VG 3S15F 4X6AF 3FKIF 3S17F 3S1NF 5E18E 2Y0SI 5M5WF 3DXJE 4C3HF 4G7HE 4Y52F 2VUMF 4KN7E 3S16F 3HOZF 3HKZK 3S1MF 5IYCF 5TMCE 5IP9F 2A6EE 2WAQK 3EQLE 4A3IF 1IW7E 2O5JE 1I50F 4OIQE 3GTKF 1WCMF 2NVYF 2A69E 3K7AF 4A3EF 4A3KF 2PMZK 1I6HF 3RZOF 4A3BF 2JA8F 4BBSF 2BE5E 3HOXF 2E2JF 5C4JF 4BY7F 1QKLA 2WB1I 4KN4E 2A6HE 4JK1E 5IYDF 5C4XF 1K83F 4LJZE 4LK1E 4OIPE 5IP7F 3S2HF 3HOUF 1Y1VF 3M3YF 4GZYE 4A3GF 4G7OE 2NVQF 5FJ8F 1TWCF 2B63F 3I4NF 5M5YF 4YFXE 3RZDF 2PPBE 2CW0E 4OINE 4LLGE 1TWHF 5M3MF 4BY1F 3WODE 4AYBK 1YNJK 3GTPF 5E17E 4MEYE 2O5IE 3GTGF 2NVXF 3I4MF 4A3LF 3S1RF 4YFNE
chains in the Genus database with same CATH superfamily
1I3QF 3GTLE 4A3JF 3CQZF 4A93E 1TWFF 3H0GE 5C3EE 1TWAF 5M3FE 4Q5SE 3HOWE 4MEXE 4XLPE 3S2DE 4C3JE 4A3MF 4Y7NE 3PO2E 3HOYE 4A93F 3H0GF 1TWGF 5M3FF 5M5XE 1Y1WE 4BY7E 5D4DE 3PO3E 3GTQE 3HOYF 3S1QF 5FLME 3GTOE 3GTJF 2NVTF 2R92E 4C2MF 1Y1WF 5D4CE 3PO3F 4A3CF 2JA7E 3GTME 1ZYRE 1R9TE 5FLMF 3GTOF 1SFOE 3S15E 5BYHE 2R93F 3S17E 4C3IE 2E2HE 2JA7F 1YNNK 4MQ9E 5IPLE 5M5WE 1SFOF 4C3HE 4YG2E 4Y52E 4XSZE 4BBRE 4C3IF 2E2HF 3S16E 3HOZE 4A3DF 2R7ZE 3S1ME 4Q4ZE 4KMUE 4YFKE 4A3FF 4OIOE 4BBRF 4A3IE 2R7ZF 2YU9E 3GTLF 3HOVE 3M4OF 5C3EF 2JA5E 1HQME 3HOWF 4XSXE 3S2DF 4C3JF 2YU9F 4BXXE 4Y7NF 3HOVF 3PO2F 4A3EE 4ZH4E 4A3KE 1I6HE 5TMFE 5D4EE 2JA5F 5IYBE 3RZOE 3S14E 4A3BE 5M5XF 4GZYE 2JA8E 2E2IE 4BBSE 4BXXF 2A68E 3GTQF 3HKZH 2JA6E 1I6VE 5C44E 4X6AE 3FKIE 5IYBF 2WAQH 4QIWH 1DZFA 2R92F 3S14F 1SMYE 4XLNE 2E2IF 3S1NE 4LK0E 4G7ZE 3GTMF 2JA6F 4OIRE 1K83E 5IP7E 5C44F 1R9TF 3H3VG 3S15F 3HOUE 3FKIF 1Y1VE 2Y0SH 2VUME 3S17F 4X6AF 5FJ8E 3S1NF 5E18E 2Y0SI 2B63E 5IYCE 5M5WF 3DXJE 4C3HF 5IP9E 4G7HE 2PMZH 4Y52F 2VUMF 4KN7E 3S16F 3HOZF 3HKZK 3S1MF 5IYCF 5TMCE 1I50E 2A6EE 2WAQK 4QIWK 5IP9F 3EQLE 3GTKE 4A3IF 1WCME 2NVYE 1IW7E 2O5JE 1EIKA 1I50F 3K7AE 4OIQE 2NVXE 3GTKF 1WCMF 4A3LE 2NVYF 3S1RE 2A69E 3HOXE 3K7AF 4A3EF 4A3KF 2PMZK 4A3JE 2E2JE 1I6HF 5C4JE 3RZOF 1TWFE 4A3BF 2JA8F 4BBSF 5IYDE 5C4XE 2BE5E 3HOXF 2WB1H 2E2JF 4A3ME 3S2HE 4A3GE 5C4JF 4BY7F 1QKLA 2WB1I 4KN4E 1TWGE 2A6HE 3M3YE 4JK1E 5IYDF 2NVQE 5C4XF 1TWCE 4AYBH 1K83F 4LJZE 4LK1E 4OIPE 5IP7F 5M5YE 3H3VF 1Y1VF 3HOUF 3I4NE 3M3YF 3GTJE 3S1QE 3S2HF 3RZDE 2NVQF 2NVTE 5FJ8F 4C2ME 1TWCF 4G7OE 4A3CE 1TWHE 2B63F 4A3GF 3I4NF 5M5YF 4YFXE 5M3ME 2KRXA 3RZDF 2CW0E 2PPBE 4BY1E 4OINE 2R93E 4LLGE 1TWHF 3GTPE 5M3MF 3GTGE 4BY1F 3WODE 3I4ME 4AYBK 1YNJK 3M4OE 4A3DE 3GTPF 1I3QE 4MEYE 2O5IE 5E17E 3GTGF 2NVXF 4A3FE 3I4MF 3CQZE 3S1RF 4A3LF 1TWAE 4YFNE
chains in the Genus database with same CATH topology
1I3QF 4A3JF 3CQZF 1TWFF 1TWAF 4Q5SE 4MEXE 4XLPE 4A3MF 4A93F 3H0GF 1TWGF 5M3FF 5D4DE 3HOYF 3S1QF 3GTJF 2NVTF 4C2MF 1Y1WF 5D4CE 3PO3F 4A3CF 1ZYRE 5FLMF 3GTOF 5BYHE 2R93F 2JA7F 1YNNK 4MQ9E 5IPLE 1SFOF 4YG2E 4C3IF 4XSZE 2E2HF 4A3DF 4Q4ZE 4KMUE 4YFKE 4A3FF 4OIOE 4BBRF 2R7ZF 3GTLF 3M4OF 5C3EF 1HQME 3HOWF 4XSXE 3S2DF 4C3JF 2YU9F 4Y7NF 3HOVF 3PO2F 4ZH4E 5TMFE 5D4EE 2JA5F 5M5XF 4BXXF 2A68E 3GTQF 1I6VE 5IYBF 2R92F 3S14F 1SMYE 4XLNE 2E2IF 4LK0E 4G7ZE 3GTMF 2JA6F 4OIRE 5C44F 1R9TF 3H3VG 3S15F 4X6AF 3FKIF 3S17F 3S1NF 5E18E 2Y0SI 5M5WF 3DXJE 4C3HF 4G7HE 4Y52F 2VUMF 4KN7E 3S16F 3HOZF 3HKZK 3S1MF 5IYCF 5TMCE 5IP9F 2A6EE 2WAQK 4QIWK 3EQLE 4A3IF 1IW7E 2O5JE 1I50F 4OIQE 3GTKF 1WCMF 2NVYF 2A69E 3K7AF 4A3EF 4A3KF 2PMZK 1I6HF 3RZOF 4A3BF 2JA8F 4BBSF 2BE5E 3HOXF 2E2JF 5C4JF 4BY7F 1QKLA 2WB1I 4KN4E 2A6HE 4JK1E 5IYDF 5C4XF 1K83F 4LJZE 4LK1E 4OIPE 5IP7F 3S2HF 3HOUF 1Y1VF 3M3YF 4GZYE 4A3GF 4G7OE 2NVQF 5FJ8F 1TWCF 2B63F 3I4NF 5M5YF 4YFXE 2KRXA 3RZDF 2CW0E 2PPBE 4OINE 4LLGE 1TWHF 5M3MF 4BY1F 3WODE 4AYBK 1YNJK 3GTPF 5E17E 4MEYE 2O5IE 3GTGF 2NVXF 3I4MF 4A3LF 3S1RF 4YFNE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I3Q F;  4A3J F;  3CQZ F;  1TWF F;  1TWA F;  4Q5S E;  4MEX E;  4XLP E;  4A3M F;  4A93 F;  3H0G F;  1TWG F;  5M3F F;  5D4D E;  3HOY F;  3S1Q F;  3GTJ F;  2NVT F;  4C2M F;  1Y1W F;  5D4C E;  3PO3 F;  4A3C F;  1ZYR E;  5FLM F;  3GTO F;  5BYH E;  2R93 F;  2JA7 F;  1YNN K;  4MQ9 E;  5IPL E;  1SFO F;  4YG2 E;  4C3I F;  4XSZ E;  2E2H F;  4A3D F;  4Q4Z E;  4KMU E;  4YFK E;  4A3F F;  4OIO E;  4BBR F;  2R7Z F;  3GTL F;  3M4O F;  5C3E F;  1HQM E;  3HOW F;  4XSX E;  3S2D F;  4C3J F;  2YU9 F;  4Y7N F;  3HOV F;  3PO2 F;  4ZH4 E;  5TMF E;  5D4E E;  2JA5 F;  5M5X F;  4BXX F;  2A68 E;  3GTQ F;  1I6V E;  5IYB F;  2R92 F;  3S14 F;  1SMY E;  4XLN E;  2E2I F;  4LK0 E;  4G7Z E;  3GTM F;  2JA6 F;  4OIR E;  5C44 F;  1R9T F;  3H3V G;  3S15 F;  4X6A F;  3FKI F;  3S17 F;  3S1N F;  5E18 E;  2Y0S I;  5M5W F;  3DXJ E;  4C3H F;  4G7H E;  4Y52 F;  2VUM F;  4KN7 E;  3S16 F;  3HOZ F;  3HKZ K;  3S1M F;  5IYC F;  5TMC E;  5IP9 F;  2A6E E;  2WAQ K;  3EQL E;  4A3I F;  1IW7 E;  2O5J E;  1I50 F;  4OIQ E;  3GTK F;  1WCM F;  2NVY F;  2A69 E;  3K7A F;  4A3E F;  4A3K F;  2PMZ K;  1I6H F;  3RZO F;  4A3B F;  2JA8 F;  4BBS F;  2BE5 E;  3HOX F;  2E2J F;  5C4J F;  4BY7 F;  1QKL A;  2WB1 I;  4KN4 E;  2A6H E;  4JK1 E;  5IYD F;  5C4X F;  1K83 F;  4LJZ E;  4LK1 E;  4OIP E;  5IP7 F;  3S2H F;  3HOU F;  1Y1V F;  3M3Y F;  4GZY E;  4A3G F;  4G7O E;  2NVQ F;  5FJ8 F;  1TWC F;  2B63 F;  3I4N F;  5M5Y F;  4YFX E;  3RZD F;  2PPB E;  2CW0 E;  4OIN E;  4LLG E;  1TWH F;  5M3M F;  4BY1 F;  3WOD E;  4AYB K;  1YNJ K;  3GTP F;  5E17 E;  4MEY E;  2O5I E;  3GTG F;  2NVX F;  3I4M F;  4A3L F;  3S1R F;  4YFN E; 
#chains in the Genus database with same CATH topology
 1I3Q F;  3GTL E;  4A3J F;  3CQZ F;  4A93 E;  1TWF F;  3H0G E;  5C3E E;  1TWA F;  5M3F E;  4Q5S E;  3HOW E;  4MEX E;  4XLP E;  3S2D E;  4C3J E;  4A3M F;  4Y7N E;  3PO2 E;  3HOY E;  4A93 F;  3H0G F;  1TWG F;  5M3F F;  5M5X E;  1Y1W E;  4BY7 E;  5D4D E;  3PO3 E;  3GTQ E;  3HOY F;  3S1Q F;  5FLM E;  3GTO E;  3GTJ F;  2NVT F;  2R92 E;  4C2M F;  1Y1W F;  5D4C E;  3PO3 F;  4A3C F;  2JA7 E;  3GTM E;  1ZYR E;  1R9T E;  5FLM F;  3GTO F;  1SFO E;  3S15 E;  5BYH E;  2R93 F;  3S17 E;  4C3I E;  2E2H E;  2JA7 F;  1YNN K;  4MQ9 E;  5IPL E;  5M5W E;  1SFO F;  4C3H E;  4YG2 E;  4Y52 E;  4XSZ E;  4BBR E;  4C3I F;  2E2H F;  3S16 E;  3HOZ E;  4A3D F;  2R7Z E;  3S1M E;  4Q4Z E;  4KMU E;  4YFK E;  4A3F F;  4OIO E;  4BBR F;  4A3I E;  2R7Z F;  2YU9 E;  3GTL F;  3HOV E;  3M4O F;  5C3E F;  2JA5 E;  1HQM E;  3HOW F;  4XSX E;  3S2D F;  4C3J F;  2YU9 F;  4BXX E;  4Y7N F;  3HOV F;  3PO2 F;  4A3E E;  4ZH4 E;  4A3K E;  1I6H E;  5TMF E;  5D4E E;  2JA5 F;  5IYB E;  3RZO E;  3S14 E;  4A3B E;  5M5X F;  4GZY E;  2JA8 E;  2E2I E;  4BBS E;  4BXX F;  2A68 E;  3GTQ F;  3HKZ H;  2JA6 E;  1I6V E;  5C44 E;  4X6A E;  3FKI E;  5IYB F;  2WAQ H;  4QIW H;  1DZF A;  2R92 F;  3S14 F;  1SMY E;  4XLN E;  2E2I F;  3S1N E;  4LK0 E;  4G7Z E;  3GTM F;  2JA6 F;  4OIR E;  1K83 E;  5IP7 E;  5C44 F;  1R9T F;  3H3V G;  3S15 F;  3HOU E;  3FKI F;  1Y1V E;  2Y0S H;  2VUM E;  3S17 F;  4X6A F;  5FJ8 E;  3S1N F;  5E18 E;  2Y0S I;  2B63 E;  5IYC E;  5M5W F;  3DXJ E;  4C3H F;  5IP9 E;  4G7H E;  2PMZ H;  4Y52 F;  2VUM F;  4KN7 E;  3S16 F;  3HOZ F;  3HKZ K;  3S1M F;  5IYC F;  5TMC E;  1I50 E;  2A6E E;  2WAQ K;  4QIW K;  5IP9 F;  3EQL E;  3GTK E;  4A3I F;  1WCM E;  2NVY E;  1IW7 E;  2O5J E;  1EIK A;  1I50 F;  3K7A E;  4OIQ E;  2NVX E;  3GTK F;  1WCM F;  4A3L E;  2NVY F;  3S1R E;  2A69 E;  3HOX E;  3K7A F;  4A3E F;  4A3K F;  2PMZ K;  4A3J E;  2E2J E;  1I6H F;  5C4J E;  3RZO F;  1TWF E;  4A3B F;  2JA8 F;  4BBS F;  5IYD E;  5C4X E;  2BE5 E;  3HOX F;  2WB1 H;  2E2J F;  4A3M E;  3S2H E;  4A3G E;  5C4J F;  4BY7 F;  1QKL A;  2WB1 I;  4KN4 E;  1TWG E;  2A6H E;  3M3Y E;  4JK1 E;  5IYD F;  2NVQ E;  5C4X F;  1TWC E;  4AYB H;  1K83 F;  4LJZ E;  4LK1 E;  4OIP E;  5IP7 F;  5M5Y E;  3H3V F;  1Y1V F;  3HOU F;  3I4N E;  3M3Y F;  3GTJ E;  3S1Q E;  3S2H F;  3RZD E;  2NVQ F;  2NVT E;  5FJ8 F;  4C2M E;  1TWC F;  4G7O E;  4A3C E;  1TWH E;  2B63 F;  4A3G F;  3I4N F;  5M5Y F;  4YFX E;  5M3M E;  2KRX A;  3RZD F;  2CW0 E;  2PPB E;  4BY1 E;  4OIN E;  2R93 E;  4LLG E;  1TWH F;  3GTP E;  5M3M F;  3GTG E;  4BY1 F;  3WOD E;  3I4M E;  4AYB K;  1YNJ K;  3M4O E;  4A3D E;  3GTP F;  1I3Q E;  4MEY E;  2O5I E;  5E17 E;  3GTG F;  2NVX F;  4A3F E;  3I4M F;  3CQZ E;  3S1R F;  4A3L F;  1TWA E;  4YFN E; 
#chains in the Genus database with same CATH homology
 1I3Q F;  4A3J F;  3CQZ F;  1TWF F;  1TWA F;  4Q5S E;  4MEX E;  4XLP E;  4A3M F;  4A93 F;  3H0G F;  1TWG F;  5M3F F;  5D4D E;  3HOY F;  3S1Q F;  3GTJ F;  2NVT F;  4C2M F;  1Y1W F;  5D4C E;  3PO3 F;  4A3C F;  1ZYR E;  5FLM F;  3GTO F;  5BYH E;  2R93 F;  2JA7 F;  1YNN K;  4MQ9 E;  5IPL E;  1SFO F;  4YG2 E;  4C3I F;  4XSZ E;  2E2H F;  4A3D F;  4Q4Z E;  4KMU E;  4YFK E;  4A3F F;  4OIO E;  4BBR F;  2R7Z F;  3GTL F;  3M4O F;  5C3E F;  1HQM E;  3HOW F;  4XSX E;  3S2D F;  4C3J F;  2YU9 F;  4Y7N F;  3HOV F;  3PO2 F;  4ZH4 E;  5TMF E;  5D4E E;  2JA5 F;  5M5X F;  4BXX F;  2A68 E;  3GTQ F;  1I6V E;  5IYB F;  2R92 F;  3S14 F;  1SMY E;  4XLN E;  2E2I F;  4LK0 E;  4G7Z E;  3GTM F;  2JA6 F;  4OIR E;  5C44 F;  1R9T F;  3H3V G;  3S15 F;  4X6A F;  3FKI F;  3S17 F;  3S1N F;  5E18 E;  2Y0S I;  5M5W F;  3DXJ E;  4C3H F;  4G7H E;  4Y52 F;  2VUM F;  4KN7 E;  3S16 F;  3HOZ F;  3HKZ K;  3S1M F;  5IYC F;  5TMC E;  5IP9 F;  2A6E E;  2WAQ K;  4QIW K;  3EQL E;  4A3I F;  1IW7 E;  2O5J E;  1I50 F;  4OIQ E;  3GTK F;  1WCM F;  2NVY F;  2A69 E;  3K7A F;  4A3E F;  4A3K F;  2PMZ K;  1I6H F;  3RZO F;  4A3B F;  2JA8 F;  4BBS F;  2BE5 E;  3HOX F;  2E2J F;  5C4J F;  4BY7 F;  1QKL A;  2WB1 I;  4KN4 E;  2A6H E;  4JK1 E;  5IYD F;  5C4X F;  1K83 F;  4LJZ E;  4LK1 E;  4OIP E;  5IP7 F;  3S2H F;  3HOU F;  1Y1V F;  3M3Y F;  4GZY E;  4A3G F;  4G7O E;  2NVQ F;  5FJ8 F;  1TWC F;  2B63 F;  3I4N F;  5M5Y F;  4YFX E;  2KRX A;  3RZD F;  2CW0 E;  2PPB E;  4OIN E;  4LLG E;  1TWH F;  5M3M F;  4BY1 F;  3WOD E;  4AYB K;  1YNJ K;  3GTP F;  5E17 E;  4MEY E;  2O5I E;  3GTG F;  2NVX F;  3I4M F;  4A3L F;  3S1R F;  4YFN E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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