3S2HE

Rna polymerase ii initiation complex with a 6-nt rna containing a 2[prime]-iodo atp
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 58
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s2hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s2hE02
5IYBE 3PO2E 3M4OE 3HOVE 2E2IE 4AYBH 5IP9E 3RZOE 2R92E 5C3EE 3GTJE 2E2JE 1TWHE 3S1QE 3S1ME 4A3EE 4BY1E 3GTPE 3HOYE 4A3BE 3S1NE 3HKZH 4A3IE 4A3DE 5IP7E 1TWFE 1DZFA 3S2DE 3S14E 3I4NE 4A93E 3H0GE 1TWCE 5FJ8E 2JA5E 4A3JE 4BBRE 3HOZE 3HOUE 4Y52E 5IYCE 3K7AE 3PO3E 4A3KE 2PMZH 3S15E 1K83E 4A3CE 1Y1WE 2NVTE 2R7ZE 3GTOE 3GTME 1R9TE 2JA8E 4C2ME 1TWAE 3S16E 5M3ME 3FKIE 4Y7NE 1I50E 2JA6E 5IYDE 4A3LE 5M5YE 3GTGE 1Y1VE 2JA7E 1TWGE 3CQZE 3GTLE 4C3IE 5C4JE 4C3JE 1I6HE 1WCME 2R93E 5C4XE 2WB1H 4X6AE 4A3FE 3GTQE 5M5XE 3H3VF 2Y0SH 2NVXE 2NVQE 5M3FE 4QIWH 4BY7E 4A3ME 4C3HE 3HOXE 3M3YE 2E2HE 1I3QE 3S2HE 3S1RE 5C44E 3S17E 2VUME 2WAQH 4BXXE 3RZDE 4BBSE 1EIKA 5FLME 3GTKE 2YU9E 1SFOE 3I4ME 5M5WE 2NVYE 3HOWE 4A3GE 2B63E
chains in the Genus database with same CATH superfamily
5IYBE 3RZOF 3PO2E 3M4OE 4LLGE 3HOVE 5C3EF 4ZH4E 3GTJF 2E2JF 2E2IE 4XSXE 4AYBH 1TWHF 3HOUF 3S1QF 1SMYE 5D4EE 1ZYRE 5IP9E 4QIWK 4Y52F 5IYCF 4BY1F 3RZOE 2R92E 4JK1E 3GTPF 3HOYF 5C3EE 1K83F 3S1NF 4A3CF 3GTJE 2E2JE 4A3IF 1TWHE 3S1QE 3S1ME 1R9TF 4A3EE 5IPLE 4YFXE 4BY1E 4C2MF 5IP7F 3GTPE 3HOYE 4A3BE 3S1NE 3HKZH 4KMUE 3FKIF 4A3IE 4A3DE 3S2DF 4OIRE 4A93F 1TWGF 5IP7E 4G7ZE 3I4NF 1TWFE 1QKLA 2A69E 3H0GF 1TWCF 5FJ8F 1IW7E 2JA5F 4C3JF 4A3JF 1DZFA 4OINE 3S2DE 3S14E 3I4NE 4A93E 4BBRF 3HOZF 5C4XF 4OIQE 3H0GE 1TWCE 5FJ8E 4Q4ZE 2JA5E 3K7AF 4A3JE 3PO3F 4A3KF 3S15F 4OIOE 4LK0E 2BE5E 1Y1WF 2NVXF 2NVQF 5M3FF 2NVTF 4BBRE 4AYBK 3HOZE 3HOUE 3GTOF 3GTMF 2R7ZF 2JA8F 4BXXF 2O5JE 4Y52E 5IYCE 1TWAF 3K7AE 3PO3E 4A3KE 4C3HF 3HOXF 2PMZH 3S15E 1K83E 5M3MF 4A3CE 3S16F 1Y1WE 4Y7NF 2NVTE 4XLNE 2R7ZE 3GTOE 1I50F 4MEXE 3GTME 1R9TE 2JA8E 2WAQK 5M5YF 5IYDF 1Y1VF 2JA6F 3S1RF 3GTGF 4A3LF 4C2ME 1TWAE 3CQZF 5C44F 2JA7F 3GTLF 4C3IF 3S16E 5M3ME 3FKIE 4MQ9E 4Y7NE 4YFNE 5C4JF 1I6HF 2O5IE 4MEYE 1I50E 2JA6E 3EQLE 1WCMF 5IYDE 5FLMF 4A3LE 5M5YE 3GTGE 1Y1VE 2R93F 2JA7E 1TWGE 3CQZE 3GTLE 4GZYE 4LK1E 3I4MF 4X6AF 4C3IE 4XLPE 3WODE 4A3FF 5C4JE 4C3JE 1I6HE 5M5XF 3GTQF 5D4CE 1WCME 2R93E 4G7OE 5C4XE 4BY7F 2WB1H 5IP9F 4X6AE 5IYBF 4G7HE 4A3MF 3M4OF 4A3FE 1YNNK 3GTQE 1HQME 5M5XE 4YG2E 3H3VF 2Y0SH 3M3YF 2NVXE 2A6EE 2NVQE 5M3FE 4QIWH 4BY7E 4KN7E 4A3ME 2PPBE 4LJZE 2E2HF 1I3QF 2R92F 3S2HF 5E17E 5TMFE 4C3HE 5E18E 3HOXE 5D4DE 3M3YE 1YNJK 2PMZK 2VUMF 3S17F 3HKZK 4Q5SE 5BYHE 3RZDF 4YFKE 4A3EF 2A68E 3H3VG 3S1MF 4OIPE 4BBSF 2E2HE 1I3QE 3S2HE 3S1RE 3GTKF 4A3BF 2YU9F 1SFOF 5C44E 2WB1I 5M5WF 2NVYF 1I6VE 3S17E 2VUME 2A6HE 2WAQH 4BXXE 4A3DF 3RZDE 4BBSE 1EIKA 2KRXA 5FLME 2CW0E 2Y0SI 3GTKE 1TWFF 3HOWF 4A3GF 2YU9E 1SFOE 5TMCE 2B63F 3I4ME 5M5WE 2NVYE 3PO2F 3HOVF 4KN4E 2E2IF 3S14F 4XSZE 3HOWE 4A3GE 3DXJE 2B63E
chains in the Genus database with same CATH topology
5IYBE 3PO2E 3M4OE 3HOVE 2E2IE 4AYBH 5IP9E 3RZOE 2R92E 5C3EE 3GTJE 2E2JE 1TWHE 3S1QE 3S1ME 4A3EE 4BY1E 3GTPE 3HOYE 4A3BE 3S1NE 3HKZH 4A3IE 4A3DE 5IP7E 1TWFE 1DZFA 3S2DE 3S14E 3I4NE 4A93E 3H0GE 1TWCE 5FJ8E 2JA5E 4A3JE 4BBRE 3HOZE 3HOUE 4Y52E 5IYCE 3K7AE 3PO3E 4A3KE 2PMZH 3S15E 1K83E 4A3CE 1Y1WE 2NVTE 2R7ZE 3GTOE 3GTME 1R9TE 2JA8E 4C2ME 1TWAE 3S16E 5M3ME 3FKIE 4Y7NE 1I50E 2JA6E 5IYDE 4A3LE 5M5YE 3GTGE 1Y1VE 2JA7E 1TWGE 3CQZE 3GTLE 4C3IE 5C4JE 4C3JE 1I6HE 1WCME 2R93E 5C4XE 2WB1H 4X6AE 4A3FE 3GTQE 5M5XE 3H3VF 2Y0SH 2NVXE 2NVQE 5M3FE 4QIWH 4BY7E 4A3ME 4C3HE 3HOXE 3M3YE 2E2HE 1I3QE 3S2HE 3S1RE 5C44E 3S17E 2VUME 2WAQH 4BXXE 3RZDE 4BBSE 1EIKA 5FLME 3GTKE 2YU9E 1SFOE 3I4ME 5M5WE 2NVYE 3HOWE 4A3GE 2B63E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYB E;  3PO2 E;  3M4O E;  3HOV E;  2E2I E;  4AYB H;  5IP9 E;  3RZO E;  2R92 E;  5C3E E;  3GTJ E;  2E2J E;  1TWH E;  3S1Q E;  3S1M E;  4A3E E;  4BY1 E;  3GTP E;  3HOY E;  4A3B E;  3S1N E;  3HKZ H;  4A3I E;  4A3D E;  5IP7 E;  1TWF E;  1DZF A;  3S2D E;  3S14 E;  3I4N E;  4A93 E;  3H0G E;  1TWC E;  5FJ8 E;  2JA5 E;  4A3J E;  4BBR E;  3HOZ E;  3HOU E;  4Y52 E;  5IYC E;  3K7A E;  3PO3 E;  4A3K E;  2PMZ H;  3S15 E;  1K83 E;  4A3C E;  1Y1W E;  2NVT E;  2R7Z E;  3GTO E;  3GTM E;  1R9T E;  2JA8 E;  4C2M E;  1TWA E;  3S16 E;  5M3M E;  3FKI E;  4Y7N E;  1I50 E;  2JA6 E;  5IYD E;  4A3L E;  5M5Y E;  3GTG E;  1Y1V E;  2JA7 E;  1TWG E;  3CQZ E;  3GTL E;  4C3I E;  5C4J E;  4C3J E;  1I6H E;  1WCM E;  2R93 E;  5C4X E;  2WB1 H;  4X6A E;  4A3F E;  3GTQ E;  5M5X E;  3H3V F;  2Y0S H;  2NVX E;  2NVQ E;  5M3F E;  4QIW H;  4BY7 E;  4A3M E;  4C3H E;  3HOX E;  3M3Y E;  2E2H E;  1I3Q E;  3S2H E;  3S1R E;  5C44 E;  3S17 E;  2VUM E;  2WAQ H;  4BXX E;  3RZD E;  4BBS E;  1EIK A;  5FLM E;  3GTK E;  2YU9 E;  1SFO E;  3I4M E;  5M5W E;  2NVY E;  3HOW E;  4A3G E;  2B63 E; 
#chains in the Genus database with same CATH topology
 5IYB E;  3RZO F;  3PO2 E;  3M4O E;  4LLG E;  3HOV E;  5C3E F;  4ZH4 E;  3GTJ F;  2E2J F;  2E2I E;  4XSX E;  4AYB H;  1TWH F;  3HOU F;  3S1Q F;  1SMY E;  5D4E E;  1ZYR E;  5IP9 E;  4QIW K;  4Y52 F;  5IYC F;  4BY1 F;  3RZO E;  2R92 E;  4JK1 E;  3GTP F;  3HOY F;  5C3E E;  1K83 F;  3S1N F;  4A3C F;  3GTJ E;  2E2J E;  4A3I F;  1TWH E;  3S1Q E;  3S1M E;  1R9T F;  4A3E E;  5IPL E;  4YFX E;  4BY1 E;  4C2M F;  5IP7 F;  3GTP E;  3HOY E;  4A3B E;  3S1N E;  3HKZ H;  4KMU E;  3FKI F;  4A3I E;  4A3D E;  3S2D F;  4OIR E;  4A93 F;  1TWG F;  5IP7 E;  4G7Z E;  3I4N F;  1TWF E;  1QKL A;  2A69 E;  3H0G F;  1TWC F;  5FJ8 F;  1IW7 E;  2JA5 F;  4C3J F;  4A3J F;  1DZF A;  4OIN E;  3S2D E;  3S14 E;  3I4N E;  4A93 E;  4BBR F;  3HOZ F;  5C4X F;  4OIQ E;  3H0G E;  1TWC E;  5FJ8 E;  4Q4Z E;  2JA5 E;  3K7A F;  4A3J E;  3PO3 F;  4A3K F;  3S15 F;  4OIO E;  4LK0 E;  2BE5 E;  1Y1W F;  2NVX F;  2NVQ F;  5M3F F;  2NVT F;  4BBR E;  4AYB K;  3HOZ E;  3HOU E;  3GTO F;  3GTM F;  2R7Z F;  2JA8 F;  4BXX F;  2O5J E;  4Y52 E;  5IYC E;  1TWA F;  3K7A E;  3PO3 E;  4A3K E;  4C3H F;  3HOX F;  2PMZ H;  3S15 E;  1K83 E;  5M3M F;  4A3C E;  3S16 F;  1Y1W E;  4Y7N F;  2NVT E;  4XLN E;  2R7Z E;  3GTO E;  1I50 F;  4MEX E;  3GTM E;  1R9T E;  2JA8 E;  2WAQ K;  5M5Y F;  5IYD F;  1Y1V F;  2JA6 F;  3S1R F;  3GTG F;  4A3L F;  4C2M E;  1TWA E;  3CQZ F;  5C44 F;  2JA7 F;  3GTL F;  4C3I F;  3S16 E;  5M3M E;  3FKI E;  4MQ9 E;  4Y7N E;  4YFN E;  5C4J F;  1I6H F;  2O5I E;  4MEY E;  1I50 E;  2JA6 E;  3EQL E;  1WCM F;  5IYD E;  5FLM F;  4A3L E;  5M5Y E;  3GTG E;  1Y1V E;  2R93 F;  2JA7 E;  1TWG E;  3CQZ E;  3GTL E;  4GZY E;  4LK1 E;  3I4M F;  4X6A F;  4C3I E;  4XLP E;  3WOD E;  4A3F F;  5C4J E;  4C3J E;  1I6H E;  5M5X F;  3GTQ F;  5D4C E;  1WCM E;  2R93 E;  4G7O E;  5C4X E;  4BY7 F;  2WB1 H;  5IP9 F;  4X6A E;  5IYB F;  4G7H E;  4A3M F;  3M4O F;  4A3F E;  1YNN K;  3GTQ E;  1HQM E;  5M5X E;  4YG2 E;  3H3V F;  2Y0S H;  3M3Y F;  2NVX E;  2A6E E;  2NVQ E;  5M3F E;  4QIW H;  4BY7 E;  4KN7 E;  4A3M E;  2PPB E;  4LJZ E;  2E2H F;  1I3Q F;  2R92 F;  3S2H F;  5E17 E;  5TMF E;  4C3H E;  5E18 E;  3HOX E;  5D4D E;  3M3Y E;  1YNJ K;  2PMZ K;  2VUM F;  3S17 F;  3HKZ K;  4Q5S E;  5BYH E;  3RZD F;  4YFK E;  4A3E F;  2A68 E;  3H3V G;  3S1M F;  4OIP E;  4BBS F;  2E2H E;  1I3Q E;  3S2H E;  3S1R E;  3GTK F;  4A3B F;  2YU9 F;  1SFO F;  5C44 E;  2WB1 I;  5M5W F;  2NVY F;  1I6V E;  3S17 E;  2VUM E;  2A6H E;  2WAQ H;  4BXX E;  4A3D F;  3RZD E;  4BBS E;  1EIK A;  2KRX A;  5FLM E;  2CW0 E;  2Y0S I;  3GTK E;  1TWF F;  3HOW F;  4A3G F;  2YU9 E;  1SFO E;  5TMC E;  2B63 F;  3I4M E;  5M5W E;  2NVY E;  3PO2 F;  3HOV F;  4KN4 E;  2E2I F;  3S14 F;  4XSZ E;  3HOW E;  4A3G E;  3DXJ E;  2B63 E; 
#chains in the Genus database with same CATH homology
 5IYB E;  3PO2 E;  3M4O E;  3HOV E;  2E2I E;  4AYB H;  5IP9 E;  3RZO E;  2R92 E;  5C3E E;  3GTJ E;  2E2J E;  1TWH E;  3S1Q E;  3S1M E;  4A3E E;  4BY1 E;  3GTP E;  3HOY E;  4A3B E;  3S1N E;  3HKZ H;  4A3I E;  4A3D E;  5IP7 E;  1TWF E;  1DZF A;  3S2D E;  3S14 E;  3I4N E;  4A93 E;  3H0G E;  1TWC E;  5FJ8 E;  2JA5 E;  4A3J E;  4BBR E;  3HOZ E;  3HOU E;  4Y52 E;  5IYC E;  3K7A E;  3PO3 E;  4A3K E;  2PMZ H;  3S15 E;  1K83 E;  4A3C E;  1Y1W E;  2NVT E;  2R7Z E;  3GTO E;  3GTM E;  1R9T E;  2JA8 E;  4C2M E;  1TWA E;  3S16 E;  5M3M E;  3FKI E;  4Y7N E;  1I50 E;  2JA6 E;  5IYD E;  4A3L E;  5M5Y E;  3GTG E;  1Y1V E;  2JA7 E;  1TWG E;  3CQZ E;  3GTL E;  4C3I E;  5C4J E;  4C3J E;  1I6H E;  1WCM E;  2R93 E;  5C4X E;  2WB1 H;  4X6A E;  4A3F E;  3GTQ E;  5M5X E;  3H3V F;  2Y0S H;  2NVX E;  2NVQ E;  5M3F E;  4QIW H;  4BY7 E;  4A3M E;  4C3H E;  3HOX E;  3M3Y E;  2E2H E;  1I3Q E;  3S2H E;  3S1R E;  5C44 E;  3S17 E;  2VUM E;  2WAQ H;  4BXX E;  3RZD E;  4BBS E;  1EIK A;  5FLM E;  3GTK E;  2YU9 E;  1SFO E;  3I4M E;  5M5W E;  2NVY E;  3HOW E;  4A3G E;  2B63 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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