3S2HF

Rna polymerase ii initiation complex with a 6-nt rna containing a 2[prime]-iodo atp
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
85
structure length
85
Chain Sequence
EKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 22
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 3s2hF00
4XSZE 4A3KF 3S1QF 3FKIF 2E2JF 3I4MF 5IYBF 4JK1E 1SMYE 4A3CF 3HOWF 5C3EF 3GTMF 1TWCF 4A3BF 1Y1WF 4C3IF 3HOYF 4C3JF 4OINE 5IPLE 5BYHE 4XLNE 3GTQF 2O5IE 4LK0E 5D4CE 3DXJE 1SFOF 4MEYE 1QKLA 2NVYF 4OIPE 3RZDF 4A3FF 2A6HE 2CW0E 1K83F 2A68E 4C3HF 3GTPF 3GTJF 3S1MF 2Y0SI 1TWGF 4A3IF 4KN4E 5D4EE 3H0GF 2YU9F 5M3FF 3S1NF 4Q4ZE 4KMUE 4Q5SE 2NVQF 3HOUF 4Y7NF 2A6EE 2VUMF 1I50F 4A3EF 1I6HF 2JA8F 3PO2F 1ZYRE 4YFXE 4X6AF 3RZOF 3M3YF 5M3MF 5TMCE 4YG2E 3S2DF 4BBSF 3H3VG 2PMZK 1TWAF 4GZYE 5M5WF 2JA6F 1WCMF 4LK1E 5IP9F 4AYBK 1HQME 3GTLF 5IYCF 3HOZF 3HKZK 4MQ9E 4C2MF 5M5YF 2R93F 2A69E 2B63F 4KN7E 2BE5E 4OIQE 4BBRF 4BY7F 4A93F 3S1RF 2WB1I 4A3GF 1I3QF 4Y52F 4YFKE 4OIOE 5IYDF 4LJZE 2NVXF 4A3LF 5E18E 3CQZF 3M4OF 2WAQK 5C4JF 5C4XF 5FJ8F 2R92F 3GTOF 2R7ZF 3S15F 4A3JF 2JA5F 3S2HF 3PO3F 1YNNK 1I6VE 4XLPE 4BY1F 3S16F 5E17E 3WODE 2O5JE 2PPBE 4XSXE 2E2IF 3GTKF 3K7AF 3EQLE 2E2HF 5FLMF 1IW7E 1YNJK 3GTGF 1TWHF 4G7HE 4BXXF 4OIRE 4YFNE 2JA7F 5D4DE 3I4NF 4ZH4E 4G7OE 3HOXF 5IP7F 4MEXE 3S17F 5M5XF 2NVTF 3HOVF 4A3DF 5TMFE 4LLGE 3S14F 5C44F 4G7ZE 4A3MF 1R9TF 1Y1VF 1TWFF
chains in the Genus database with same CATH superfamily
1I3QE 4XSZE 4A3KF 3S17E 2WAQH 3S1QF 4Y52E 4A3DE 3S14E 5IYDE 5C44E 3FKIF 2E2JF 2NVXE 1R9TE 1Y1VE 5IYBF 4JK1E 1SMYE 3I4MF 4A3LE 4A3CF 3HOWF 5C3EF 3GTMF 3S1QE 5C4XE 5FJ8E 2R92E 3GTOE 1TWCF 2R7ZE 4A3BF 1Y1WF 4C3IF 4A3JE 3S2HE 3PO3E 2E2JE 4C3JF 3HOYF 4OINE 5IPLE 5BYHE 4XLNE 4A3BE 3GTQF 2O5IE 2E2IE 4LK0E 5D4CE 3DXJE 1TWCE 3GTKE 3K7AE 3H3VF 1SFOF 4MEYE 5IP7E 1QKLA 4C3JE 2NVYF 4OIPE 2E2HE 3RZDF 4A3FF 2A6HE 2CW0E 1K83F 1TWHE 4BXXE 3GTQE 2A68E 4C3HF 3GTPF 3GTJF 2JA7E 3S1MF 2Y0SI 1TWGF 2NVYE 4A3IF 4KN4E 5D4EE 3H0GF 4A3FE 5M3FF 5M5XE 3RZDE 2YU9F 2NVTE 1K83E 3HOVE 3S1NF 4Q4ZE 4KMUE 4Q5SE 3GTPE 4A3ME 2NVQF 3HOUF 4Y7NF 2A6EE 4A3IE 1TWFE 2YU9E 3H0GE 1I50F 5M3FE 1DZFA 4A3KE 4A3EF 1I6HF 2VUMF 3S1NE 2JA8F 3FKIE 3PO2F 1ZYRE 5IYBE 2NVQE 4Y7NE 3HOUE 3I4ME 4A3CE 4YFXE 2VUME 4A3EE 3HOWE 4X6AF 5C3EE 4QIWK 4QIWH 3GTME 3RZOF 3M3YF 5M3MF 4C3IE 1Y1WE 3HOYE 5TMCE 3PO2E 4YG2E 3S2DF 4BBSF 3H3VG 2PMZK 1TWAF 4GZYE 5M5WF 1SFOE 2JA6F 1WCMF 4LK1E 5IP9F 4AYBK 1HQME 3GTLF 5IYCF 3HOZF 1TWAE 4C3HE 3HKZK 4MQ9E 3GTJE 5M5WE 4C2MF 3S1ME 5M5YF 2R93F 2A69E 1TWGE 5IP9E 2B63F 4KN7E 3GTLE 2BE5E 4OIQE 4BBRF 4BY7F 4A93F 5M5YE 3S1RF 2WB1I 4A3GF 1I3QF 1I50E 2Y0SH 4Y52F 1I6HE 4YFKE 4OIOE 5IYDF 2JA8E 4LJZE 2NVXF 4A3LF 5E18E 3CQZF 3S1RE 4A3GE 2KRXA 4X6AE 3M4OF 1EIKA 2WAQK 2PMZH 5C4JF 5FJ8F 2R92F 3GTOF 5C4XF 3RZOE 2R7ZF 3S15F 3M3YE 5M3ME 4A3JF 2JA5F 3S2HF 3PO3F 1YNNK 1I6VE 4AYBH 3CQZE 4XLPE 4BY1F 3S16F 3S2DE 5E17E 3WODE 4BBSE 2O5JE 2PPBE 3M4OE 4XSXE 5C4JE 2E2IF 3HKZH 2WB1H 3S15E 3GTKF 3K7AF 3EQLE 2JA5E 2E2HF 5FLMF 2JA6E 1IW7E 1WCME 1YNJK 3S16E 4BY1E 3GTGF 3HOZE 5IYCE 1TWHF 4G7HE 4BXXF 4OIRE 4YFNE 2JA7F 4C2ME 5D4DE 3I4NF 4ZH4E 4G7OE 2R93E 5FLME 3HOXF 5IP7F 4MEXE 3S17F 5M5XF 2B63E 3GTGE 2NVTF 3HOVF 4A3DF 5TMFE 4LLGE 3S14F 4BBRE 5C44F 4G7ZE 4BY7E 4A93E 4A3MF 1R9TF 1Y1VF 3I4NE 3HOXE 1TWFF
chains in the Genus database with same CATH topology
4XSZE 4A3KF 3S1QF 3FKIF 2E2JF 3I4MF 5IYBF 4JK1E 1SMYE 4A3CF 3HOWF 5C3EF 3GTMF 1TWCF 4A3BF 1Y1WF 4C3IF 3HOYF 4C3JF 4OINE 5IPLE 5BYHE 4XLNE 3GTQF 2O5IE 4LK0E 5D4CE 3DXJE 1SFOF 4MEYE 1QKLA 2NVYF 4OIPE 3RZDF 4A3FF 2A6HE 2CW0E 1K83F 2A68E 4C3HF 3GTPF 3GTJF 3S1MF 2Y0SI 1TWGF 4A3IF 4KN4E 5D4EE 3H0GF 2YU9F 5M3FF 3S1NF 4Q4ZE 4KMUE 4Q5SE 2NVQF 3HOUF 4Y7NF 2A6EE 2VUMF 1I50F 4A3EF 1I6HF 2JA8F 3PO2F 1ZYRE 4YFXE 4X6AF 4QIWK 3RZOF 3M3YF 5M3MF 5TMCE 4YG2E 3S2DF 4BBSF 3H3VG 2PMZK 1TWAF 4GZYE 5M5WF 2JA6F 1WCMF 4LK1E 5IP9F 4AYBK 1HQME 3GTLF 5IYCF 3HOZF 3HKZK 4MQ9E 4C2MF 5M5YF 2R93F 2A69E 2B63F 4KN7E 2BE5E 4OIQE 4BBRF 4BY7F 4A93F 3S1RF 2WB1I 4A3GF 1I3QF 4Y52F 4YFKE 4OIOE 5IYDF 4LJZE 2NVXF 4A3LF 5E18E 3CQZF 2KRXA 3M4OF 2WAQK 5C4JF 5C4XF 5FJ8F 2R92F 3GTOF 2R7ZF 3S15F 4A3JF 2JA5F 3S2HF 3PO3F 1YNNK 1I6VE 4XLPE 4BY1F 3S16F 5E17E 3WODE 2O5JE 2PPBE 4XSXE 2E2IF 3GTKF 3K7AF 3EQLE 2E2HF 5FLMF 1IW7E 1YNJK 3GTGF 1TWHF 4G7HE 4BXXF 4OIRE 4YFNE 2JA7F 5D4DE 3I4NF 4ZH4E 4G7OE 3HOXF 5IP7F 4MEXE 3S17F 5M5XF 2NVTF 3HOVF 4A3DF 5TMFE 4LLGE 3S14F 5C44F 4G7ZE 4A3MF 1R9TF 1Y1VF 1TWFF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSZ E;  4A3K F;  3S1Q F;  3FKI F;  2E2J F;  3I4M F;  5IYB F;  4JK1 E;  1SMY E;  4A3C F;  3HOW F;  5C3E F;  3GTM F;  1TWC F;  4A3B F;  1Y1W F;  4C3I F;  3HOY F;  4C3J F;  4OIN E;  5IPL E;  5BYH E;  4XLN E;  3GTQ F;  2O5I E;  4LK0 E;  5D4C E;  3DXJ E;  1SFO F;  4MEY E;  1QKL A;  2NVY F;  4OIP E;  3RZD F;  4A3F F;  2A6H E;  2CW0 E;  1K83 F;  2A68 E;  4C3H F;  3GTP F;  3GTJ F;  3S1M F;  2Y0S I;  1TWG F;  4A3I F;  4KN4 E;  5D4E E;  3H0G F;  2YU9 F;  5M3F F;  3S1N F;  4Q4Z E;  4KMU E;  4Q5S E;  2NVQ F;  3HOU F;  4Y7N F;  2A6E E;  2VUM F;  1I50 F;  4A3E F;  1I6H F;  2JA8 F;  3PO2 F;  1ZYR E;  4YFX E;  4X6A F;  3RZO F;  3M3Y F;  5M3M F;  5TMC E;  4YG2 E;  3S2D F;  4BBS F;  3H3V G;  2PMZ K;  1TWA F;  4GZY E;  5M5W F;  2JA6 F;  1WCM F;  4LK1 E;  5IP9 F;  4AYB K;  1HQM E;  3GTL F;  5IYC F;  3HOZ F;  3HKZ K;  4MQ9 E;  4C2M F;  5M5Y F;  2R93 F;  2A69 E;  2B63 F;  4KN7 E;  2BE5 E;  4OIQ E;  4BBR F;  4BY7 F;  4A93 F;  3S1R F;  2WB1 I;  4A3G F;  1I3Q F;  4Y52 F;  4YFK E;  4OIO E;  5IYD F;  4LJZ E;  2NVX F;  4A3L F;  5E18 E;  3CQZ F;  3M4O F;  2WAQ K;  5C4J F;  5C4X F;  5FJ8 F;  2R92 F;  3GTO F;  2R7Z F;  3S15 F;  4A3J F;  2JA5 F;  3S2H F;  3PO3 F;  1YNN K;  1I6V E;  4XLP E;  4BY1 F;  3S16 F;  5E17 E;  3WOD E;  2O5J E;  2PPB E;  4XSX E;  2E2I F;  3GTK F;  3K7A F;  3EQL E;  2E2H F;  5FLM F;  1IW7 E;  1YNJ K;  3GTG F;  1TWH F;  4G7H E;  4BXX F;  4OIR E;  4YFN E;  2JA7 F;  5D4D E;  3I4N F;  4ZH4 E;  4G7O E;  3HOX F;  5IP7 F;  4MEX E;  3S17 F;  5M5X F;  2NVT F;  3HOV F;  4A3D F;  5TMF E;  4LLG E;  3S14 F;  5C44 F;  4G7Z E;  4A3M F;  1R9T F;  1Y1V F;  1TWF F; 
#chains in the Genus database with same CATH topology
 1I3Q E;  4XSZ E;  4A3K F;  3S17 E;  2WAQ H;  3S1Q F;  4Y52 E;  4A3D E;  3S14 E;  5IYD E;  5C44 E;  3FKI F;  2E2J F;  2NVX E;  1R9T E;  1Y1V E;  5IYB F;  4JK1 E;  1SMY E;  3I4M F;  4A3L E;  4A3C F;  3HOW F;  5C3E F;  3GTM F;  3S1Q E;  5C4X E;  5FJ8 E;  2R92 E;  3GTO E;  1TWC F;  2R7Z E;  4A3B F;  1Y1W F;  4C3I F;  4A3J E;  3S2H E;  3PO3 E;  2E2J E;  4C3J F;  3HOY F;  4OIN E;  5IPL E;  5BYH E;  4XLN E;  4A3B E;  3GTQ F;  2O5I E;  2E2I E;  4LK0 E;  5D4C E;  3DXJ E;  1TWC E;  3GTK E;  3K7A E;  3H3V F;  1SFO F;  4MEY E;  5IP7 E;  1QKL A;  4C3J E;  2NVY F;  4OIP E;  2E2H E;  3RZD F;  4A3F F;  2A6H E;  2CW0 E;  1K83 F;  1TWH E;  4BXX E;  3GTQ E;  2A68 E;  4C3H F;  3GTP F;  3GTJ F;  2JA7 E;  3S1M F;  2Y0S I;  1TWG F;  2NVY E;  4A3I F;  4KN4 E;  5D4E E;  3H0G F;  4A3F E;  5M3F F;  5M5X E;  3RZD E;  2YU9 F;  2NVT E;  1K83 E;  3HOV E;  3S1N F;  4Q4Z E;  4KMU E;  4Q5S E;  3GTP E;  4A3M E;  2NVQ F;  3HOU F;  4Y7N F;  2A6E E;  4A3I E;  1TWF E;  2YU9 E;  3H0G E;  1I50 F;  5M3F E;  1DZF A;  4A3K E;  4A3E F;  1I6H F;  2VUM F;  3S1N E;  2JA8 F;  3FKI E;  3PO2 F;  1ZYR E;  5IYB E;  2NVQ E;  4Y7N E;  3HOU E;  3I4M E;  4A3C E;  4YFX E;  2VUM E;  4A3E E;  3HOW E;  4X6A F;  5C3E E;  4QIW K;  4QIW H;  3GTM E;  3RZO F;  3M3Y F;  5M3M F;  4C3I E;  1Y1W E;  3HOY E;  5TMC E;  3PO2 E;  4YG2 E;  3S2D F;  4BBS F;  3H3V G;  2PMZ K;  1TWA F;  4GZY E;  5M5W F;  1SFO E;  2JA6 F;  1WCM F;  4LK1 E;  5IP9 F;  4AYB K;  1HQM E;  3GTL F;  5IYC F;  3HOZ F;  1TWA E;  4C3H E;  3HKZ K;  4MQ9 E;  3GTJ E;  5M5W E;  4C2M F;  3S1M E;  5M5Y F;  2R93 F;  2A69 E;  1TWG E;  5IP9 E;  2B63 F;  4KN7 E;  3GTL E;  2BE5 E;  4OIQ E;  4BBR F;  4BY7 F;  4A93 F;  5M5Y E;  3S1R F;  2WB1 I;  4A3G F;  1I3Q F;  1I50 E;  2Y0S H;  4Y52 F;  1I6H E;  4YFK E;  4OIO E;  5IYD F;  2JA8 E;  4LJZ E;  2NVX F;  4A3L F;  5E18 E;  3CQZ F;  3S1R E;  4A3G E;  2KRX A;  4X6A E;  3M4O F;  1EIK A;  2WAQ K;  2PMZ H;  5C4J F;  5FJ8 F;  2R92 F;  3GTO F;  5C4X F;  3RZO E;  2R7Z F;  3S15 F;  3M3Y E;  5M3M E;  4A3J F;  2JA5 F;  3S2H F;  3PO3 F;  1YNN K;  1I6V E;  4AYB H;  3CQZ E;  4XLP E;  4BY1 F;  3S16 F;  3S2D E;  5E17 E;  3WOD E;  4BBS E;  2O5J E;  2PPB E;  3M4O E;  4XSX E;  5C4J E;  2E2I F;  3HKZ H;  2WB1 H;  3S15 E;  3GTK F;  3K7A F;  3EQL E;  2JA5 E;  2E2H F;  5FLM F;  2JA6 E;  1IW7 E;  1WCM E;  1YNJ K;  3S16 E;  4BY1 E;  3GTG F;  3HOZ E;  5IYC E;  1TWH F;  4G7H E;  4BXX F;  4OIR E;  4YFN E;  2JA7 F;  4C2M E;  5D4D E;  3I4N F;  4ZH4 E;  4G7O E;  2R93 E;  5FLM E;  3HOX F;  5IP7 F;  4MEX E;  3S17 F;  5M5X F;  2B63 E;  3GTG E;  2NVT F;  3HOV F;  4A3D F;  5TMF E;  4LLG E;  3S14 F;  4BBR E;  5C44 F;  4G7Z E;  4BY7 E;  4A93 E;  4A3M F;  1R9T F;  1Y1V F;  3I4N E;  3HOX E;  1TWF F; 
#chains in the Genus database with same CATH homology
 4XSZ E;  4A3K F;  3S1Q F;  3FKI F;  2E2J F;  3I4M F;  5IYB F;  4JK1 E;  1SMY E;  4A3C F;  3HOW F;  5C3E F;  3GTM F;  1TWC F;  4A3B F;  1Y1W F;  4C3I F;  3HOY F;  4C3J F;  4OIN E;  5IPL E;  5BYH E;  4XLN E;  3GTQ F;  2O5I E;  4LK0 E;  5D4C E;  3DXJ E;  1SFO F;  4MEY E;  1QKL A;  2NVY F;  4OIP E;  3RZD F;  4A3F F;  2A6H E;  2CW0 E;  1K83 F;  2A68 E;  4C3H F;  3GTP F;  3GTJ F;  3S1M F;  2Y0S I;  1TWG F;  4A3I F;  4KN4 E;  5D4E E;  3H0G F;  2YU9 F;  5M3F F;  3S1N F;  4Q4Z E;  4KMU E;  4Q5S E;  2NVQ F;  3HOU F;  4Y7N F;  2A6E E;  2VUM F;  1I50 F;  4A3E F;  1I6H F;  2JA8 F;  3PO2 F;  1ZYR E;  4YFX E;  4X6A F;  4QIW K;  3RZO F;  3M3Y F;  5M3M F;  5TMC E;  4YG2 E;  3S2D F;  4BBS F;  3H3V G;  2PMZ K;  1TWA F;  4GZY E;  5M5W F;  2JA6 F;  1WCM F;  4LK1 E;  5IP9 F;  4AYB K;  1HQM E;  3GTL F;  5IYC F;  3HOZ F;  3HKZ K;  4MQ9 E;  4C2M F;  5M5Y F;  2R93 F;  2A69 E;  2B63 F;  4KN7 E;  2BE5 E;  4OIQ E;  4BBR F;  4BY7 F;  4A93 F;  3S1R F;  2WB1 I;  4A3G F;  1I3Q F;  4Y52 F;  4YFK E;  4OIO E;  5IYD F;  4LJZ E;  2NVX F;  4A3L F;  5E18 E;  3CQZ F;  2KRX A;  3M4O F;  2WAQ K;  5C4J F;  5C4X F;  5FJ8 F;  2R92 F;  3GTO F;  2R7Z F;  3S15 F;  4A3J F;  2JA5 F;  3S2H F;  3PO3 F;  1YNN K;  1I6V E;  4XLP E;  4BY1 F;  3S16 F;  5E17 E;  3WOD E;  2O5J E;  2PPB E;  4XSX E;  2E2I F;  3GTK F;  3K7A F;  3EQL E;  2E2H F;  5FLM F;  1IW7 E;  1YNJ K;  3GTG F;  1TWH F;  4G7H E;  4BXX F;  4OIR E;  4YFN E;  2JA7 F;  5D4D E;  3I4N F;  4ZH4 E;  4G7O E;  3HOX F;  5IP7 F;  4MEX E;  3S17 F;  5M5X F;  2NVT F;  3HOV F;  4A3D F;  5TMF E;  4LLG E;  3S14 F;  5C44 F;  4G7Z E;  4A3M F;  1R9T F;  1Y1V F;  1TWF F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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