3T62D

Crystal structure of recombinant kunitz type serine protease inhibitor-1 from the caribbean sea anemone stichodactyla helianthus in complex with bovine chymotrypsin
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
54
structure length
54
Chain Sequence
SICSEPKKVGRCKGYFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHQCRAICR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Stichodactyla helianthus
molecule keywords Chymotrypsinogen A
total genus 7
structure length 54
sequence length 54
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2011-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3t62D00
1EAWB 3T62D 1BHCA 4BD9B 4Y10I 3FP7J 1UUAA 1BIKA 1P2KI 1TFXC 3BTQI 2DDJA 1DEMA 1KNTA 3AUGA 4Y0YI 2ZVXA 2FI3I 1BRBI 1NAGA 4U32X 1D0DA 3TGKI 3FP8I 3LDJA 3AUCA 4WXVC 4BQDA 3M7QB 2UUYB 1MTND 1BPTA 3P95E 1F5RI 1TAWB 1DENA 2W8XA 3GYMI 1F7ZI 4DG4C 8PTIA 2M01A 3BTFI 1T8OB 3BTDI 3BYBA 1P2II 1AALA 1LD6A 1KIGI 3L33E 1PITA 4WWYC 2FTMB 9PTIA 1DTKA 3BTEI 3TGJI 3OTJI 1BPIA 1B0CA 1KTHA 1EJMB 2ODYE 2JOTA 2FI4I 3BTMI 1TPAI 1ADZA 1FAKI 1CA0D 4NTXB 2PTCI 2KAII 3AUEA 1LD5A 2RA3C 1P2NB 4DTGK 3UOUB 3BTHI 3TPII 1P2OB 3U1JE 5JB7A 5C67C 1T8LB 4ISLB 1CO7I 1G6XA 1BF0A 1QLQA 1P2JI 1TOCR 1FANA 1BUNB 1TAPA 3BTWI 3UIRC 1K6UA 2TGPI 6PTIA 5JB4A 1FY8I 1YC0I 2M99A 1D0DB 1BTIA 1JV9A 1Y62A 2FI5I 3L3TE 1P2MB 1T8MB 2DDIA 4BNRI 3TGII 1JC6A 3WNYA 1YLCB 2FTLI 1UUBA 1OA55 1IRHA 4NTYB 2ZJXA 7PTIA 2J6DA 1BRCI 2LFLA 2IJOI 3BTKI 1BTHP 1OA65 1ZJDB 3AUHA 2UUXA 3AUBA 3AUIA 1TCPA 2KCRA 4ISNB 3P92E 1DTXA 3FP6I 1AAPA 2TPII 1KUNA 3BTGI 3D65I 3OFWA 2HEXA 4U30W 1T7CB 1ZR0B 5JB6A 2KNTA 3LDMA 4Y0ZI 1JV8A 1YLDB 3BTTI 4Y11I 4NTWB 4TPII 1T8NB 2CA7A 1CBWD 4PTIA 3AUDA 5JB5A 1BZXI 4ISOB 1BZ5A 1P2QB 3CI7A 3LDIA 2R9PE 1SHPA 2LFKA 5PTIA 1YKTB
chains in the Genus database with same CATH superfamily
1EAWB 3T62D 1BHCA 4BD9B 4Y10I 3FP7J 1UUAA 1BIKA 1P2KI 1TFXC 3BTQI 2DDJA 1DEMA 1KNTA 3AUGA 4Y0YI 2ZVXA 2FI3I 1BRBI 1NAGA 4U32X 1D0DA 3TGKI 3FP8I 3LDJA 3AUCA 4WXVC 4BQDA 3M7QB 2UUYB 1MTND 1BPTA 3P95E 1F5RI 1TAWB 1DENA 2W8XA 3GYMI 1F7ZI 4DG4C 8PTIA 2M01A 3BTFI 1T8OB 3BTDI 3BYBA 1P2II 1AALA 1LD6A 1KIGI 3L33E 1PITA 4WWYC 2FTMB 9PTIA 1DTKA 3BTEI 3TGJI 3OTJI 1BPIA 1B0CA 1KTHA 1EJMB 2ODYE 2JOTA 2FI4I 3BTMI 1TPAI 1ADZA 1FAKI 1CA0D 4NTXB 2PTCI 2KAII 3AUEA 1LD5A 2RA3C 1P2NB 4DTGK 3UOUB 3BTHI 3TPII 1P2OB 3U1JE 5JB7A 5C67C 1T8LB 4ISLB 1CO7I 1G6XA 1BF0A 1QLQA 1P2JI 1TOCR 1FANA 1BUNB 1TAPA 3BTWI 3UIRC 1K6UA 2TGPI 6PTIA 5JB4A 1FY8I 1YC0I 2M99A 1D0DB 1BTIA 1JV9A 1Y62A 2FI5I 3L3TE 1P2MB 1T8MB 2DDIA 4BNRI 3TGII 1JC6A 3WNYA 1YLCB 2FTLI 1UUBA 1OA55 1IRHA 4NTYB 2ZJXA 7PTIA 2J6DA 1BRCI 2LFLA 2IJOI 3BTKI 1BTHP 1OA65 1ZJDB 3AUHA 2UUXA 3AUBA 3AUIA 1TCPA 2KCRA 4ISNB 3P92E 1DTXA 3FP6I 1AAPA 2TPII 1KUNA 3BTGI 3D65I 3OFWA 2HEXA 4U30W 1T7CB 1ZR0B 5JB6A 2KNTA 3LDMA 4Y0ZI 1JV8A 1YLDB 3BTTI 4Y11I 4NTWB 4TPII 1T8NB 2CA7A 1CBWD 4PTIA 3AUDA 5JB5A 1BZXI 4ISOB 1BZ5A 1P2QB 3CI7A 3LDIA 2R9PE 1SHPA 2LFKA 5PTIA 1YKTB
chains in the Genus database with same CATH topology
1EAWB 3T62D 1BHCA 4BD9B 4Y10I 3FP7J 1UUAA 1BIKA 1P2KI 1TFXC 3BTQI 2DDJA 1DEMA 1KNTA 3AUGA 4Y0YI 2ZVXA 2FI3I 1BRBI 1NAGA 4U32X 1D0DA 3TGKI 3FP8I 3LDJA 3AUCA 4WXVC 4BQDA 3M7QB 2UUYB 1MTND 1BPTA 3P95E 1F5RI 1TAWB 1DENA 2W8XA 3GYMI 1F7ZI 4DG4C 8PTIA 2M01A 3BTFI 1T8OB 3BTDI 3BYBA 1P2II 1AALA 1LD6A 1KIGI 3L33E 1PITA 4WWYC 2FTMB 9PTIA 1DTKA 3BTEI 3TGJI 3OTJI 1BPIA 1B0CA 1KTHA 1EJMB 2ODYE 2JOTA 2FI4I 3BTMI 1TPAI 1ADZA 1FAKI 1CA0D 4NTXB 2PTCI 2KAII 3AUEA 1LD5A 2RA3C 1P2NB 4DTGK 3UOUB 3BTHI 3TPII 1P2OB 3U1JE 5JB7A 5C67C 1T8LB 4ISLB 1CO7I 1G6XA 1BF0A 1QLQA 1P2JI 1TOCR 1FANA 1BUNB 1TAPA 3BTWI 3UIRC 1K6UA 2TGPI 6PTIA 5JB4A 1FY8I 1YC0I 2M99A 1D0DB 1BTIA 1JV9A 1Y62A 2FI5I 3L3TE 1P2MB 1T8MB 2DDIA 4BNRI 3TGII 1JC6A 3WNYA 1YLCB 2FTLI 1UUBA 1OA55 1IRHA 4NTYB 2ZJXA 7PTIA 2J6DA 1BRCI 2LFLA 2IJOI 3BTKI 1BTHP 1OA65 1ZJDB 3AUHA 2UUXA 3AUBA 3AUIA 1TCPA 2KCRA 4ISNB 3P92E 1DTXA 3FP6I 1AAPA 2TPII 1KUNA 3BTGI 3D65I 3OFWA 2HEXA 4U30W 1T7CB 1ZR0B 5JB6A 2KNTA 3LDMA 4Y0ZI 1JV8A 1YLDB 3BTTI 4Y11I 4NTWB 4TPII 1T8NB 2CA7A 1CBWD 4PTIA 3AUDA 5JB5A 1BZXI 4ISOB 1BZ5A 1P2QB 3CI7A 3LDIA 2R9PE 1SHPA 2LFKA 5PTIA 1YKTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAW B;  3T62 D;  1BHC A;  4BD9 B;  4Y10 I;  3FP7 J;  1UUA A;  1BIK A;  1P2K I;  1TFX C;  3BTQ I;  2DDJ A;  1DEM A;  1KNT A;  3AUG A;  4Y0Y I;  2ZVX A;  2FI3 I;  1BRB I;  1NAG A;  4U32 X;  1D0D A;  3TGK I;  3FP8 I;  3LDJ A;  3AUC A;  4WXV C;  4BQD A;  3M7Q B;  2UUY B;  1MTN D;  1BPT A;  3P95 E;  1F5R I;  1TAW B;  1DEN A;  2W8X A;  3GYM I;  1F7Z I;  4DG4 C;  8PTI A;  2M01 A;  3BTF I;  1T8O B;  3BTD I;  3BYB A;  1P2I I;  1AAL A;  1LD6 A;  1KIG I;  3L33 E;  1PIT A;  4WWY C;  2FTM B;  9PTI A;  1DTK A;  3BTE I;  3TGJ I;  3OTJ I;  1BPI A;  1B0C A;  1KTH A;  1EJM B;  2ODY E;  2JOT A;  2FI4 I;  3BTM I;  1TPA I;  1ADZ A;  1FAK I;  1CA0 D;  4NTX B;  2PTC I;  2KAI I;  3AUE A;  1LD5 A;  2RA3 C;  1P2N B;  4DTG K;  3UOU B;  3BTH I;  3TPI I;  1P2O B;  3U1J E;  5JB7 A;  5C67 C;  1T8L B;  4ISL B;  1CO7 I;  1G6X A;  1BF0 A;  1QLQ A;  1P2J I;  1TOC R;  1FAN A;  1BUN B;  1TAP A;  3BTW I;  3UIR C;  1K6U A;  2TGP I;  6PTI A;  5JB4 A;  1FY8 I;  1YC0 I;  2M99 A;  1D0D B;  1BTI A;  1JV9 A;  1Y62 A;  2FI5 I;  3L3T E;  1P2M B;  1T8M B;  2DDI A;  4BNR I;  3TGI I;  1JC6 A;  3WNY A;  1YLC B;  2FTL I;  1UUB A;  1OA5 5;  1IRH A;  4NTY B;  2ZJX A;  7PTI A;  2J6D A;  1BRC I;  2LFL A;  2IJO I;  3BTK I;  1BTH P;  1OA6 5;  1ZJD B;  3AUH A;  2UUX A;  3AUB A;  3AUI A;  1TCP A;  2KCR A;  4ISN B;  3P92 E;  1DTX A;  3FP6 I;  1AAP A;  2TPI I;  1KUN A;  3BTG I;  3D65 I;  3OFW A;  2HEX A;  4U30 W;  1T7C B;  1ZR0 B;  5JB6 A;  2KNT A;  3LDM A;  4Y0Z I;  1JV8 A;  1YLD B;  3BTT I;  4Y11 I;  4NTW B;  4TPI I;  1T8N B;  2CA7 A;  1CBW D;  4PTI A;  3AUD A;  5JB5 A;  1BZX I;  4ISO B;  1BZ5 A;  1P2Q B;  3CI7 A;  3LDI A;  2R9P E;  1SHP A;  2LFK A;  5PTI A;  1YKT B; 
#chains in the Genus database with same CATH topology
 1EAW B;  3T62 D;  1BHC A;  4BD9 B;  4Y10 I;  3FP7 J;  1UUA A;  1BIK A;  1P2K I;  1TFX C;  3BTQ I;  2DDJ A;  1DEM A;  1KNT A;  3AUG A;  4Y0Y I;  2ZVX A;  2FI3 I;  1BRB I;  1NAG A;  4U32 X;  1D0D A;  3TGK I;  3FP8 I;  3LDJ A;  3AUC A;  4WXV C;  4BQD A;  3M7Q B;  2UUY B;  1MTN D;  1BPT A;  3P95 E;  1F5R I;  1TAW B;  1DEN A;  2W8X A;  3GYM I;  1F7Z I;  4DG4 C;  8PTI A;  2M01 A;  3BTF I;  1T8O B;  3BTD I;  3BYB A;  1P2I I;  1AAL A;  1LD6 A;  1KIG I;  3L33 E;  1PIT A;  4WWY C;  2FTM B;  9PTI A;  1DTK A;  3BTE I;  3TGJ I;  3OTJ I;  1BPI A;  1B0C A;  1KTH A;  1EJM B;  2ODY E;  2JOT A;  2FI4 I;  3BTM I;  1TPA I;  1ADZ A;  1FAK I;  1CA0 D;  4NTX B;  2PTC I;  2KAI I;  3AUE A;  1LD5 A;  2RA3 C;  1P2N B;  4DTG K;  3UOU B;  3BTH I;  3TPI I;  1P2O B;  3U1J E;  5JB7 A;  5C67 C;  1T8L B;  4ISL B;  1CO7 I;  1G6X A;  1BF0 A;  1QLQ A;  1P2J I;  1TOC R;  1FAN A;  1BUN B;  1TAP A;  3BTW I;  3UIR C;  1K6U A;  2TGP I;  6PTI A;  5JB4 A;  1FY8 I;  1YC0 I;  2M99 A;  1D0D B;  1BTI A;  1JV9 A;  1Y62 A;  2FI5 I;  3L3T E;  1P2M B;  1T8M B;  2DDI A;  4BNR I;  3TGI I;  1JC6 A;  3WNY A;  1YLC B;  2FTL I;  1UUB A;  1OA5 5;  1IRH A;  4NTY B;  2ZJX A;  7PTI A;  2J6D A;  1BRC I;  2LFL A;  2IJO I;  3BTK I;  1BTH P;  1OA6 5;  1ZJD B;  3AUH A;  2UUX A;  3AUB A;  3AUI A;  1TCP A;  2KCR A;  4ISN B;  3P92 E;  1DTX A;  3FP6 I;  1AAP A;  2TPI I;  1KUN A;  3BTG I;  3D65 I;  3OFW A;  2HEX A;  4U30 W;  1T7C B;  1ZR0 B;  5JB6 A;  2KNT A;  3LDM A;  4Y0Z I;  1JV8 A;  1YLD B;  3BTT I;  4Y11 I;  4NTW B;  4TPI I;  1T8N B;  2CA7 A;  1CBW D;  4PTI A;  3AUD A;  5JB5 A;  1BZX I;  4ISO B;  1BZ5 A;  1P2Q B;  3CI7 A;  3LDI A;  2R9P E;  1SHP A;  2LFK A;  5PTI A;  1YKT B; 
#chains in the Genus database with same CATH homology
 1EAW B;  3T62 D;  1BHC A;  4BD9 B;  4Y10 I;  3FP7 J;  1UUA A;  1BIK A;  1P2K I;  1TFX C;  3BTQ I;  2DDJ A;  1DEM A;  1KNT A;  3AUG A;  4Y0Y I;  2ZVX A;  2FI3 I;  1BRB I;  1NAG A;  4U32 X;  1D0D A;  3TGK I;  3FP8 I;  3LDJ A;  3AUC A;  4WXV C;  4BQD A;  3M7Q B;  2UUY B;  1MTN D;  1BPT A;  3P95 E;  1F5R I;  1TAW B;  1DEN A;  2W8X A;  3GYM I;  1F7Z I;  4DG4 C;  8PTI A;  2M01 A;  3BTF I;  1T8O B;  3BTD I;  3BYB A;  1P2I I;  1AAL A;  1LD6 A;  1KIG I;  3L33 E;  1PIT A;  4WWY C;  2FTM B;  9PTI A;  1DTK A;  3BTE I;  3TGJ I;  3OTJ I;  1BPI A;  1B0C A;  1KTH A;  1EJM B;  2ODY E;  2JOT A;  2FI4 I;  3BTM I;  1TPA I;  1ADZ A;  1FAK I;  1CA0 D;  4NTX B;  2PTC I;  2KAI I;  3AUE A;  1LD5 A;  2RA3 C;  1P2N B;  4DTG K;  3UOU B;  3BTH I;  3TPI I;  1P2O B;  3U1J E;  5JB7 A;  5C67 C;  1T8L B;  4ISL B;  1CO7 I;  1G6X A;  1BF0 A;  1QLQ A;  1P2J I;  1TOC R;  1FAN A;  1BUN B;  1TAP A;  3BTW I;  3UIR C;  1K6U A;  2TGP I;  6PTI A;  5JB4 A;  1FY8 I;  1YC0 I;  2M99 A;  1D0D B;  1BTI A;  1JV9 A;  1Y62 A;  2FI5 I;  3L3T E;  1P2M B;  1T8M B;  2DDI A;  4BNR I;  3TGI I;  1JC6 A;  3WNY A;  1YLC B;  2FTL I;  1UUB A;  1OA5 5;  1IRH A;  4NTY B;  2ZJX A;  7PTI A;  2J6D A;  1BRC I;  2LFL A;  2IJO I;  3BTK I;  1BTH P;  1OA6 5;  1ZJD B;  3AUH A;  2UUX A;  3AUB A;  3AUI A;  1TCP A;  2KCR A;  4ISN B;  3P92 E;  1DTX A;  3FP6 I;  1AAP A;  2TPI I;  1KUN A;  3BTG I;  3D65 I;  3OFW A;  2HEX A;  4U30 W;  1T7C B;  1ZR0 B;  5JB6 A;  2KNT A;  3LDM A;  4Y0Z I;  1JV8 A;  1YLD B;  3BTT I;  4Y11 I;  4NTW B;  4TPI I;  1T8N B;  2CA7 A;  1CBW D;  4PTI A;  3AUD A;  5JB5 A;  1BZX I;  4ISO B;  1BZ5 A;  1P2Q B;  3CI7 A;  3LDI A;  2R9P E;  1SHP A;  2LFK A;  5PTI A;  1YKT B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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