3TGII

Wild-type rat anionic trypsin complexed with bovine pancreatic trypsin inhibitor (bpti)
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
56
structure length
56
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure
pubmed rcsb
molecule tags Complex (serine protease/inhibitor)
molecule keywords TRYPSIN
total genus 9
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1998-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3tgiI00
1DENA 1AAPA 1G6XA 4Y10I 2KAII 1B0CA 1KTHA 3GYMI 1BUNB 9PTIA 1BZ5A 1BPTA 1YLCB 3D65I 1ADZA 5JB6A 2FI3I 2KNTA 4WXVC 3TGKI 2UUYB 3U1JE 1JC6A 1EAWB 1P2NB 2LFLA 2RA3C 3BTQI 3FP8I 1D0DB 1JV9A 3CI7A 1F7ZI 3UIRC 4NTWB 3P92E 1BIKA 1P2KI 2ZVXA 3BTKI 2TGPI 1FY8I 4ISNB 3AUIA 1UUAA 3AUCA 4BQDA 3BTEI 1CA0D 1ZR0B 1D0DA 6PTIA 3T62D 1YKTB 2ODYE 1T7CB 1KIGI 3LDMA 1NAGA 4Y11I 1BRCI 1KUNA 1FANA 3AUEA 1TOCR 4PTIA 2DDJA 2HEXA 1BHCA 3LDJA 1BZXI 1YLDB 3OFWA 1TPAI 5PTIA 4DTGK 3TGII 4BNRI 4U30W 1F5RI 1IRHA 3BYBA 1P2II 3BTFI 1OA55 2ZJXA 1DTXA 1Y62A 3LDIA 4Y0YI 1TFXC 1OA65 3OTJI 2IJOI 2M99A 1T8LB 2LFKA 2UUXA 3BTDI 4WWYC 3BTWI 1P2JI 1P2OB 1FAKI 2FTLI 2R9PE 3AUHA 3FP7J 3AUGA 1BRBI 3BTTI 1DEMA 1QLQA 1TAWB 2KCRA 4DG4C 3BTHI 3BTGI 1AALA 1KNTA 4TPII 3UOUB 1CO7I 4Y0ZI 2FTMB 3BTMI 2W8XA 1K6UA 2JOTA 1JV8A 4ISOB 1LD6A 2CA7A 1P2QB 1BTIA 3TGJI 1BF0A 1TAPA 2FI4I 2M01A 1DTKA 1UUBA 1T8MB 1TCPA 1T8OB 1ZJDB 2J6DA 1P2MB 1T8NB 3P95E 3M7QB 4BD9B 3TPII 1BTHP 1CBWD 1SHPA 4U32X 2PTCI 5JB4A 2TPII 2FI5I 1EJMB 1BPIA 3FP6I 5JB5A 5JB7A 1LD5A 7PTIA 1MTND 5C67C 2DDIA 3L3TE 4NTXB 4NTYB 3L33E 3WNYA 4ISLB 1YC0I 3AUBA 1PITA 8PTIA 3AUDA
chains in the Genus database with same CATH superfamily
1DENA 1AAPA 1G6XA 4Y10I 2KAII 1B0CA 1KTHA 3GYMI 1BUNB 9PTIA 1BZ5A 1BPTA 1YLCB 3D65I 1ADZA 5JB6A 2FI3I 2KNTA 4WXVC 3TGKI 2UUYB 3U1JE 1JC6A 1EAWB 1P2NB 2LFLA 2RA3C 3BTQI 3FP8I 1D0DB 1JV9A 3CI7A 1F7ZI 3UIRC 4NTWB 3P92E 1BIKA 1P2KI 2ZVXA 3BTKI 2TGPI 1FY8I 4ISNB 3AUIA 1UUAA 3AUCA 4BQDA 3BTEI 1CA0D 1ZR0B 1D0DA 6PTIA 3T62D 1YKTB 2ODYE 1T7CB 1KIGI 3LDMA 1NAGA 4Y11I 1BRCI 1KUNA 1FANA 3AUEA 1TOCR 4PTIA 2DDJA 2HEXA 1BHCA 3LDJA 1BZXI 1YLDB 3OFWA 1TPAI 5PTIA 4DTGK 3TGII 4BNRI 4U30W 1F5RI 1IRHA 3BYBA 1P2II 3BTFI 1OA55 2ZJXA 1DTXA 1Y62A 3LDIA 4Y0YI 1TFXC 1OA65 3OTJI 2IJOI 2M99A 1T8LB 2LFKA 2UUXA 3BTDI 4WWYC 3BTWI 1P2JI 1P2OB 1FAKI 2FTLI 2R9PE 3AUHA 3FP7J 3AUGA 1BRBI 3BTTI 1DEMA 1QLQA 1TAWB 2KCRA 4DG4C 3BTHI 3BTGI 1AALA 1KNTA 4TPII 3UOUB 1CO7I 4Y0ZI 2FTMB 3BTMI 2W8XA 1K6UA 2JOTA 1JV8A 4ISOB 1LD6A 2CA7A 1P2QB 1BTIA 3TGJI 1BF0A 1TAPA 2FI4I 2M01A 1DTKA 1UUBA 1T8MB 1TCPA 1T8OB 1ZJDB 2J6DA 1P2MB 1T8NB 3P95E 3M7QB 4BD9B 3TPII 1BTHP 1CBWD 1SHPA 4U32X 2PTCI 5JB4A 2TPII 2FI5I 1EJMB 1BPIA 3FP6I 5JB5A 5JB7A 1LD5A 7PTIA 1MTND 5C67C 2DDIA 3L3TE 4NTXB 4NTYB 3L33E 3WNYA 4ISLB 1YC0I 3AUBA 1PITA 8PTIA 3AUDA
chains in the Genus database with same CATH topology
1DENA 1AAPA 1G6XA 4Y10I 2KAII 1B0CA 1KTHA 3GYMI 1BUNB 9PTIA 1BZ5A 1BPTA 1YLCB 3D65I 1ADZA 5JB6A 2FI3I 2KNTA 4WXVC 3TGKI 2UUYB 3U1JE 1JC6A 1EAWB 1P2NB 2LFLA 2RA3C 3BTQI 3FP8I 1D0DB 1JV9A 3CI7A 1F7ZI 3UIRC 4NTWB 3P92E 1BIKA 1P2KI 2ZVXA 3BTKI 2TGPI 1FY8I 4ISNB 3AUIA 1UUAA 3AUCA 4BQDA 3BTEI 1CA0D 1ZR0B 1D0DA 6PTIA 3T62D 1YKTB 2ODYE 1T7CB 1KIGI 3LDMA 1NAGA 4Y11I 1BRCI 1KUNA 1FANA 3AUEA 1TOCR 4PTIA 2DDJA 2HEXA 1BHCA 3LDJA 1BZXI 1YLDB 3OFWA 1TPAI 5PTIA 4DTGK 3TGII 4BNRI 4U30W 1F5RI 1IRHA 3BYBA 1P2II 3BTFI 1OA55 2ZJXA 1DTXA 1Y62A 3LDIA 4Y0YI 1TFXC 1OA65 3OTJI 2IJOI 2M99A 1T8LB 2LFKA 2UUXA 3BTDI 4WWYC 3BTWI 1P2JI 1P2OB 1FAKI 2FTLI 2R9PE 3AUHA 3FP7J 3AUGA 1BRBI 3BTTI 1DEMA 1QLQA 1TAWB 2KCRA 4DG4C 3BTHI 3BTGI 1AALA 1KNTA 4TPII 3UOUB 1CO7I 4Y0ZI 2FTMB 3BTMI 2W8XA 1K6UA 2JOTA 1JV8A 4ISOB 1LD6A 2CA7A 1P2QB 1BTIA 3TGJI 1BF0A 1TAPA 2FI4I 2M01A 1DTKA 1UUBA 1T8MB 1TCPA 1T8OB 1ZJDB 2J6DA 1P2MB 1T8NB 3P95E 3M7QB 4BD9B 3TPII 1BTHP 1CBWD 1SHPA 4U32X 2PTCI 5JB4A 2TPII 2FI5I 1EJMB 1BPIA 3FP6I 5JB5A 5JB7A 1LD5A 7PTIA 1MTND 5C67C 2DDIA 3L3TE 4NTXB 4NTYB 3L33E 3WNYA 4ISLB 1YC0I 3AUBA 1PITA 8PTIA 3AUDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DEN A;  1AAP A;  1G6X A;  4Y10 I;  2KAI I;  1B0C A;  1KTH A;  3GYM I;  1BUN B;  9PTI A;  1BZ5 A;  1BPT A;  1YLC B;  3D65 I;  1ADZ A;  5JB6 A;  2FI3 I;  2KNT A;  4WXV C;  3TGK I;  2UUY B;  3U1J E;  1JC6 A;  1EAW B;  1P2N B;  2LFL A;  2RA3 C;  3BTQ I;  3FP8 I;  1D0D B;  1JV9 A;  3CI7 A;  1F7Z I;  3UIR C;  4NTW B;  3P92 E;  1BIK A;  1P2K I;  2ZVX A;  3BTK I;  2TGP I;  1FY8 I;  4ISN B;  3AUI A;  1UUA A;  3AUC A;  4BQD A;  3BTE I;  1CA0 D;  1ZR0 B;  1D0D A;  6PTI A;  3T62 D;  1YKT B;  2ODY E;  1T7C B;  1KIG I;  3LDM A;  1NAG A;  4Y11 I;  1BRC I;  1KUN A;  1FAN A;  3AUE A;  1TOC R;  4PTI A;  2DDJ A;  2HEX A;  1BHC A;  3LDJ A;  1BZX I;  1YLD B;  3OFW A;  1TPA I;  5PTI A;  4DTG K;  3TGI I;  4BNR I;  4U30 W;  1F5R I;  1IRH A;  3BYB A;  1P2I I;  3BTF I;  1OA5 5;  2ZJX A;  1DTX A;  1Y62 A;  3LDI A;  4Y0Y I;  1TFX C;  1OA6 5;  3OTJ I;  2IJO I;  2M99 A;  1T8L B;  2LFK A;  2UUX A;  3BTD I;  4WWY C;  3BTW I;  1P2J I;  1P2O B;  1FAK I;  2FTL I;  2R9P E;  3AUH A;  3FP7 J;  3AUG A;  1BRB I;  3BTT I;  1DEM A;  1QLQ A;  1TAW B;  2KCR A;  4DG4 C;  3BTH I;  3BTG I;  1AAL A;  1KNT A;  4TPI I;  3UOU B;  1CO7 I;  4Y0Z I;  2FTM B;  3BTM I;  2W8X A;  1K6U A;  2JOT A;  1JV8 A;  4ISO B;  1LD6 A;  2CA7 A;  1P2Q B;  1BTI A;  3TGJ I;  1BF0 A;  1TAP A;  2FI4 I;  2M01 A;  1DTK A;  1UUB A;  1T8M B;  1TCP A;  1T8O B;  1ZJD B;  2J6D A;  1P2M B;  1T8N B;  3P95 E;  3M7Q B;  4BD9 B;  3TPI I;  1BTH P;  1CBW D;  1SHP A;  4U32 X;  2PTC I;  5JB4 A;  2TPI I;  2FI5 I;  1EJM B;  1BPI A;  3FP6 I;  5JB5 A;  5JB7 A;  1LD5 A;  7PTI A;  1MTN D;  5C67 C;  2DDI A;  3L3T E;  4NTX B;  4NTY B;  3L33 E;  3WNY A;  4ISL B;  1YC0 I;  3AUB A;  1PIT A;  8PTI A;  3AUD A; 
#chains in the Genus database with same CATH topology
 1DEN A;  1AAP A;  1G6X A;  4Y10 I;  2KAI I;  1B0C A;  1KTH A;  3GYM I;  1BUN B;  9PTI A;  1BZ5 A;  1BPT A;  1YLC B;  3D65 I;  1ADZ A;  5JB6 A;  2FI3 I;  2KNT A;  4WXV C;  3TGK I;  2UUY B;  3U1J E;  1JC6 A;  1EAW B;  1P2N B;  2LFL A;  2RA3 C;  3BTQ I;  3FP8 I;  1D0D B;  1JV9 A;  3CI7 A;  1F7Z I;  3UIR C;  4NTW B;  3P92 E;  1BIK A;  1P2K I;  2ZVX A;  3BTK I;  2TGP I;  1FY8 I;  4ISN B;  3AUI A;  1UUA A;  3AUC A;  4BQD A;  3BTE I;  1CA0 D;  1ZR0 B;  1D0D A;  6PTI A;  3T62 D;  1YKT B;  2ODY E;  1T7C B;  1KIG I;  3LDM A;  1NAG A;  4Y11 I;  1BRC I;  1KUN A;  1FAN A;  3AUE A;  1TOC R;  4PTI A;  2DDJ A;  2HEX A;  1BHC A;  3LDJ A;  1BZX I;  1YLD B;  3OFW A;  1TPA I;  5PTI A;  4DTG K;  3TGI I;  4BNR I;  4U30 W;  1F5R I;  1IRH A;  3BYB A;  1P2I I;  3BTF I;  1OA5 5;  2ZJX A;  1DTX A;  1Y62 A;  3LDI A;  4Y0Y I;  1TFX C;  1OA6 5;  3OTJ I;  2IJO I;  2M99 A;  1T8L B;  2LFK A;  2UUX A;  3BTD I;  4WWY C;  3BTW I;  1P2J I;  1P2O B;  1FAK I;  2FTL I;  2R9P E;  3AUH A;  3FP7 J;  3AUG A;  1BRB I;  3BTT I;  1DEM A;  1QLQ A;  1TAW B;  2KCR A;  4DG4 C;  3BTH I;  3BTG I;  1AAL A;  1KNT A;  4TPI I;  3UOU B;  1CO7 I;  4Y0Z I;  2FTM B;  3BTM I;  2W8X A;  1K6U A;  2JOT A;  1JV8 A;  4ISO B;  1LD6 A;  2CA7 A;  1P2Q B;  1BTI A;  3TGJ I;  1BF0 A;  1TAP A;  2FI4 I;  2M01 A;  1DTK A;  1UUB A;  1T8M B;  1TCP A;  1T8O B;  1ZJD B;  2J6D A;  1P2M B;  1T8N B;  3P95 E;  3M7Q B;  4BD9 B;  3TPI I;  1BTH P;  1CBW D;  1SHP A;  4U32 X;  2PTC I;  5JB4 A;  2TPI I;  2FI5 I;  1EJM B;  1BPI A;  3FP6 I;  5JB5 A;  5JB7 A;  1LD5 A;  7PTI A;  1MTN D;  5C67 C;  2DDI A;  3L3T E;  4NTX B;  4NTY B;  3L33 E;  3WNY A;  4ISL B;  1YC0 I;  3AUB A;  1PIT A;  8PTI A;  3AUD A; 
#chains in the Genus database with same CATH homology
 1DEN A;  1AAP A;  1G6X A;  4Y10 I;  2KAI I;  1B0C A;  1KTH A;  3GYM I;  1BUN B;  9PTI A;  1BZ5 A;  1BPT A;  1YLC B;  3D65 I;  1ADZ A;  5JB6 A;  2FI3 I;  2KNT A;  4WXV C;  3TGK I;  2UUY B;  3U1J E;  1JC6 A;  1EAW B;  1P2N B;  2LFL A;  2RA3 C;  3BTQ I;  3FP8 I;  1D0D B;  1JV9 A;  3CI7 A;  1F7Z I;  3UIR C;  4NTW B;  3P92 E;  1BIK A;  1P2K I;  2ZVX A;  3BTK I;  2TGP I;  1FY8 I;  4ISN B;  3AUI A;  1UUA A;  3AUC A;  4BQD A;  3BTE I;  1CA0 D;  1ZR0 B;  1D0D A;  6PTI A;  3T62 D;  1YKT B;  2ODY E;  1T7C B;  1KIG I;  3LDM A;  1NAG A;  4Y11 I;  1BRC I;  1KUN A;  1FAN A;  3AUE A;  1TOC R;  4PTI A;  2DDJ A;  2HEX A;  1BHC A;  3LDJ A;  1BZX I;  1YLD B;  3OFW A;  1TPA I;  5PTI A;  4DTG K;  3TGI I;  4BNR I;  4U30 W;  1F5R I;  1IRH A;  3BYB A;  1P2I I;  3BTF I;  1OA5 5;  2ZJX A;  1DTX A;  1Y62 A;  3LDI A;  4Y0Y I;  1TFX C;  1OA6 5;  3OTJ I;  2IJO I;  2M99 A;  1T8L B;  2LFK A;  2UUX A;  3BTD I;  4WWY C;  3BTW I;  1P2J I;  1P2O B;  1FAK I;  2FTL I;  2R9P E;  3AUH A;  3FP7 J;  3AUG A;  1BRB I;  3BTT I;  1DEM A;  1QLQ A;  1TAW B;  2KCR A;  4DG4 C;  3BTH I;  3BTG I;  1AAL A;  1KNT A;  4TPI I;  3UOU B;  1CO7 I;  4Y0Z I;  2FTM B;  3BTM I;  2W8X A;  1K6U A;  2JOT A;  1JV8 A;  4ISO B;  1LD6 A;  2CA7 A;  1P2Q B;  1BTI A;  3TGJ I;  1BF0 A;  1TAP A;  2FI4 I;  2M01 A;  1DTK A;  1UUB A;  1T8M B;  1TCP A;  1T8O B;  1ZJD B;  2J6D A;  1P2M B;  1T8N B;  3P95 E;  3M7Q B;  4BD9 B;  3TPI I;  1BTH P;  1CBW D;  1SHP A;  4U32 X;  2PTC I;  5JB4 A;  2TPI I;  2FI5 I;  1EJM B;  1BPI A;  3FP6 I;  5JB5 A;  5JB7 A;  1LD5 A;  7PTI A;  1MTN D;  5C67 C;  2DDI A;  3L3T E;  4NTX B;  4NTY B;  3L33 E;  3WNY A;  4ISL B;  1YC0 I;  3AUB A;  1PIT A;  8PTI A;  3AUD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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