3TGJI

S195a trypsinogen complexed with bovine pancreatic trypsin inhibitor (bpti)
Total Genus 7
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
56
structure length
56
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure
pubmed rcsb
molecule tags Complex (serine protease/inhibitor)
source organism Rattus norvegicus
molecule keywords TRYPSIN
total genus 7
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1998-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3tgjI00
1P2OB 2J6DA 5PTIA 2LFLA 3BYBA 4Y11I 3FP6I 2TPII 1BZ5A 3L33E 1KUNA 1BZXI 2TGPI 1CO7I 1P2KI 1T8LB 3AUBA 3LDJA 3BTGI 1FANA 1TAPA 2FI5I 7PTIA 1JV9A 3AUCA 3FP8I 3BTMI 1IRHA 9PTIA 3BTFI 5C67C 4BD9B 1TOCR 4ISOB 1D0DB 1EAWB 1F7ZI 1BTIA 1BUNB 1KTHA 3UIRC 1JC6A 1TAWB 4Y10I 3TGII 2PTCI 1KIGI 3UOUB 2FI3I 2KAII 2ZVXA 3L3TE 3P92E 1PITA 3OFWA 1BF0A 1DEMA 3M7QB 4U30W 1G6XA 1Y62A 3BTTI 1BRCI 1DENA 1BRBI 1ZR0B 3T62D 1JV8A 3TGJI 2UUXA 1TPAI 1T7CB 1T8OB 2FTLI 3P95E 2FTMB 6PTIA 1DTKA 3AUGA 2FI4I 3LDIA 3BTDI 3BTHI 4NTXB 3OTJI 4Y0ZI 1YC0I 2RA3C 1MTND 1DTXA 1FY8I 2DDJA 1OA55 1P2JI 3FP7J 1TFXC 4BQDA 1SHPA 1UUAA 1K6UA 4Y0YI 3TPII 2CA7A 1CA0D 1ZJDB 2ZJXA 1NAGA 1T8NB 2KNTA 1AAPA 1KNTA 3U1JE 1EJMB 3BTKI 1F5RI 1P2II 2M99A 5JB4A 5JB6A 4NTWB 1B0CA 4ISLB 3TGKI 8PTIA 1P2NB 3AUEA 4PTIA 3AUDA 2R9PE 1D0DA 2W8XA 4NTYB 1CBWD 3BTWI 2UUYB 4U32X 3AUIA 4BNRI 3WNYA 1QLQA 1OA65 4DG4C 2HEXA 1P2QB 2KCRA 2LFKA 3BTQI 4ISNB 1FAKI 1YKTB 2JOTA 1YLCB 1BPIA 3BTEI 3CI7A 3AUHA 4WWYC 1BTHP 3LDMA 5JB5A 1P2MB 2IJOI 1TCPA 4DTGK 1UUBA 1LD6A 1YLDB 1LD5A 1AALA 1BPTA 1T8MB 5JB7A 1BHCA 1ADZA 3GYMI 2ODYE 1BIKA 2DDIA 4TPII 3D65I 2M01A 4WXVC
chains in the Genus database with same CATH superfamily
1P2OB 2J6DA 5PTIA 2LFLA 3BYBA 4Y11I 3FP6I 2TPII 1BZ5A 3L33E 1KUNA 1BZXI 2TGPI 1CO7I 1P2KI 1T8LB 3AUBA 3LDJA 3BTGI 1FANA 1TAPA 2FI5I 7PTIA 1JV9A 3AUCA 3FP8I 3BTMI 1IRHA 9PTIA 3BTFI 5C67C 4BD9B 1TOCR 4ISOB 1D0DB 1EAWB 1F7ZI 1BTIA 1BUNB 1KTHA 3UIRC 1JC6A 1TAWB 4Y10I 3TGII 2PTCI 1KIGI 3UOUB 2FI3I 2KAII 2ZVXA 3L3TE 3P92E 1PITA 3OFWA 1BF0A 1DEMA 3M7QB 4U30W 1G6XA 1Y62A 3BTTI 1BRCI 1DENA 1BRBI 1ZR0B 3T62D 1JV8A 3TGJI 2UUXA 1TPAI 1T7CB 1T8OB 2FTLI 3P95E 2FTMB 6PTIA 1DTKA 3AUGA 2FI4I 3LDIA 3BTDI 3BTHI 4NTXB 3OTJI 4Y0ZI 1YC0I 2RA3C 1MTND 1DTXA 1FY8I 2DDJA 1OA55 1P2JI 3FP7J 1TFXC 4BQDA 1SHPA 1UUAA 1K6UA 4Y0YI 3TPII 2CA7A 1CA0D 1ZJDB 2ZJXA 1NAGA 1T8NB 2KNTA 1AAPA 1KNTA 3U1JE 1EJMB 3BTKI 1F5RI 1P2II 2M99A 5JB4A 5JB6A 4NTWB 1B0CA 4ISLB 3TGKI 8PTIA 1P2NB 3AUEA 4PTIA 3AUDA 2R9PE 1D0DA 2W8XA 4NTYB 1CBWD 3BTWI 2UUYB 4U32X 3AUIA 4BNRI 3WNYA 1QLQA 1OA65 4DG4C 2HEXA 1P2QB 2KCRA 2LFKA 3BTQI 4ISNB 1FAKI 1YKTB 2JOTA 1YLCB 1BPIA 3BTEI 3CI7A 3AUHA 4WWYC 1BTHP 3LDMA 5JB5A 1P2MB 2IJOI 1TCPA 4DTGK 1UUBA 1LD6A 1YLDB 1LD5A 1AALA 1BPTA 1T8MB 5JB7A 1BHCA 1ADZA 3GYMI 2ODYE 1BIKA 2DDIA 4TPII 3D65I 2M01A 4WXVC
chains in the Genus database with same CATH topology
1P2OB 2J6DA 5PTIA 2LFLA 3BYBA 4Y11I 3FP6I 2TPII 1BZ5A 3L33E 1KUNA 1BZXI 2TGPI 1CO7I 1P2KI 1T8LB 3AUBA 3LDJA 3BTGI 1FANA 1TAPA 2FI5I 7PTIA 1JV9A 3AUCA 3FP8I 3BTMI 1IRHA 9PTIA 3BTFI 5C67C 4BD9B 1TOCR 4ISOB 1D0DB 1EAWB 1F7ZI 1BTIA 1BUNB 1KTHA 3UIRC 1JC6A 1TAWB 4Y10I 3TGII 2PTCI 1KIGI 3UOUB 2FI3I 2KAII 2ZVXA 3L3TE 3P92E 1PITA 3OFWA 1BF0A 1DEMA 3M7QB 4U30W 1G6XA 1Y62A 3BTTI 1BRCI 1DENA 1BRBI 1ZR0B 3T62D 1JV8A 3TGJI 2UUXA 1TPAI 1T7CB 1T8OB 2FTLI 3P95E 2FTMB 6PTIA 1DTKA 3AUGA 2FI4I 3LDIA 3BTDI 3BTHI 4NTXB 3OTJI 4Y0ZI 1YC0I 2RA3C 1MTND 1DTXA 1FY8I 2DDJA 1OA55 1P2JI 3FP7J 1TFXC 4BQDA 1SHPA 1UUAA 1K6UA 4Y0YI 3TPII 2CA7A 1CA0D 1ZJDB 2ZJXA 1NAGA 1T8NB 2KNTA 1AAPA 1KNTA 3U1JE 1EJMB 3BTKI 1F5RI 1P2II 2M99A 5JB4A 5JB6A 4NTWB 1B0CA 4ISLB 3TGKI 8PTIA 1P2NB 3AUEA 4PTIA 3AUDA 2R9PE 1D0DA 2W8XA 4NTYB 1CBWD 3BTWI 2UUYB 4U32X 3AUIA 4BNRI 3WNYA 1QLQA 1OA65 4DG4C 2HEXA 1P2QB 2KCRA 2LFKA 3BTQI 4ISNB 1FAKI 1YKTB 2JOTA 1YLCB 1BPIA 3BTEI 3CI7A 3AUHA 4WWYC 1BTHP 3LDMA 5JB5A 1P2MB 2IJOI 1TCPA 4DTGK 1UUBA 1LD6A 1YLDB 1LD5A 1AALA 1BPTA 1T8MB 5JB7A 1BHCA 1ADZA 3GYMI 2ODYE 1BIKA 2DDIA 4TPII 3D65I 2M01A 4WXVC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P2O B;  2J6D A;  5PTI A;  2LFL A;  3BYB A;  4Y11 I;  3FP6 I;  2TPI I;  1BZ5 A;  3L33 E;  1KUN A;  1BZX I;  2TGP I;  1CO7 I;  1P2K I;  1T8L B;  3AUB A;  3LDJ A;  3BTG I;  1FAN A;  1TAP A;  2FI5 I;  7PTI A;  1JV9 A;  3AUC A;  3FP8 I;  3BTM I;  1IRH A;  9PTI A;  3BTF I;  5C67 C;  4BD9 B;  1TOC R;  4ISO B;  1D0D B;  1EAW B;  1F7Z I;  1BTI A;  1BUN B;  1KTH A;  3UIR C;  1JC6 A;  1TAW B;  4Y10 I;  3TGI I;  2PTC I;  1KIG I;  3UOU B;  2FI3 I;  2KAI I;  2ZVX A;  3L3T E;  3P92 E;  1PIT A;  3OFW A;  1BF0 A;  1DEM A;  3M7Q B;  4U30 W;  1G6X A;  1Y62 A;  3BTT I;  1BRC I;  1DEN A;  1BRB I;  1ZR0 B;  3T62 D;  1JV8 A;  3TGJ I;  2UUX A;  1TPA I;  1T7C B;  1T8O B;  2FTL I;  3P95 E;  2FTM B;  6PTI A;  1DTK A;  3AUG A;  2FI4 I;  3LDI A;  3BTD I;  3BTH I;  4NTX B;  3OTJ I;  4Y0Z I;  1YC0 I;  2RA3 C;  1MTN D;  1DTX A;  1FY8 I;  2DDJ A;  1OA5 5;  1P2J I;  3FP7 J;  1TFX C;  4BQD A;  1SHP A;  1UUA A;  1K6U A;  4Y0Y I;  3TPI I;  2CA7 A;  1CA0 D;  1ZJD B;  2ZJX A;  1NAG A;  1T8N B;  2KNT A;  1AAP A;  1KNT A;  3U1J E;  1EJM B;  3BTK I;  1F5R I;  1P2I I;  2M99 A;  5JB4 A;  5JB6 A;  4NTW B;  1B0C A;  4ISL B;  3TGK I;  8PTI A;  1P2N B;  3AUE A;  4PTI A;  3AUD A;  2R9P E;  1D0D A;  2W8X A;  4NTY B;  1CBW D;  3BTW I;  2UUY B;  4U32 X;  3AUI A;  4BNR I;  3WNY A;  1QLQ A;  1OA6 5;  4DG4 C;  2HEX A;  1P2Q B;  2KCR A;  2LFK A;  3BTQ I;  4ISN B;  1FAK I;  1YKT B;  2JOT A;  1YLC B;  1BPI A;  3BTE I;  3CI7 A;  3AUH A;  4WWY C;  1BTH P;  3LDM A;  5JB5 A;  1P2M B;  2IJO I;  1TCP A;  4DTG K;  1UUB A;  1LD6 A;  1YLD B;  1LD5 A;  1AAL A;  1BPT A;  1T8M B;  5JB7 A;  1BHC A;  1ADZ A;  3GYM I;  2ODY E;  1BIK A;  2DDI A;  4TPI I;  3D65 I;  2M01 A;  4WXV C; 
#chains in the Genus database with same CATH topology
 1P2O B;  2J6D A;  5PTI A;  2LFL A;  3BYB A;  4Y11 I;  3FP6 I;  2TPI I;  1BZ5 A;  3L33 E;  1KUN A;  1BZX I;  2TGP I;  1CO7 I;  1P2K I;  1T8L B;  3AUB A;  3LDJ A;  3BTG I;  1FAN A;  1TAP A;  2FI5 I;  7PTI A;  1JV9 A;  3AUC A;  3FP8 I;  3BTM I;  1IRH A;  9PTI A;  3BTF I;  5C67 C;  4BD9 B;  1TOC R;  4ISO B;  1D0D B;  1EAW B;  1F7Z I;  1BTI A;  1BUN B;  1KTH A;  3UIR C;  1JC6 A;  1TAW B;  4Y10 I;  3TGI I;  2PTC I;  1KIG I;  3UOU B;  2FI3 I;  2KAI I;  2ZVX A;  3L3T E;  3P92 E;  1PIT A;  3OFW A;  1BF0 A;  1DEM A;  3M7Q B;  4U30 W;  1G6X A;  1Y62 A;  3BTT I;  1BRC I;  1DEN A;  1BRB I;  1ZR0 B;  3T62 D;  1JV8 A;  3TGJ I;  2UUX A;  1TPA I;  1T7C B;  1T8O B;  2FTL I;  3P95 E;  2FTM B;  6PTI A;  1DTK A;  3AUG A;  2FI4 I;  3LDI A;  3BTD I;  3BTH I;  4NTX B;  3OTJ I;  4Y0Z I;  1YC0 I;  2RA3 C;  1MTN D;  1DTX A;  1FY8 I;  2DDJ A;  1OA5 5;  1P2J I;  3FP7 J;  1TFX C;  4BQD A;  1SHP A;  1UUA A;  1K6U A;  4Y0Y I;  3TPI I;  2CA7 A;  1CA0 D;  1ZJD B;  2ZJX A;  1NAG A;  1T8N B;  2KNT A;  1AAP A;  1KNT A;  3U1J E;  1EJM B;  3BTK I;  1F5R I;  1P2I I;  2M99 A;  5JB4 A;  5JB6 A;  4NTW B;  1B0C A;  4ISL B;  3TGK I;  8PTI A;  1P2N B;  3AUE A;  4PTI A;  3AUD A;  2R9P E;  1D0D A;  2W8X A;  4NTY B;  1CBW D;  3BTW I;  2UUY B;  4U32 X;  3AUI A;  4BNR I;  3WNY A;  1QLQ A;  1OA6 5;  4DG4 C;  2HEX A;  1P2Q B;  2KCR A;  2LFK A;  3BTQ I;  4ISN B;  1FAK I;  1YKT B;  2JOT A;  1YLC B;  1BPI A;  3BTE I;  3CI7 A;  3AUH A;  4WWY C;  1BTH P;  3LDM A;  5JB5 A;  1P2M B;  2IJO I;  1TCP A;  4DTG K;  1UUB A;  1LD6 A;  1YLD B;  1LD5 A;  1AAL A;  1BPT A;  1T8M B;  5JB7 A;  1BHC A;  1ADZ A;  3GYM I;  2ODY E;  1BIK A;  2DDI A;  4TPI I;  3D65 I;  2M01 A;  4WXV C; 
#chains in the Genus database with same CATH homology
 1P2O B;  2J6D A;  5PTI A;  2LFL A;  3BYB A;  4Y11 I;  3FP6 I;  2TPI I;  1BZ5 A;  3L33 E;  1KUN A;  1BZX I;  2TGP I;  1CO7 I;  1P2K I;  1T8L B;  3AUB A;  3LDJ A;  3BTG I;  1FAN A;  1TAP A;  2FI5 I;  7PTI A;  1JV9 A;  3AUC A;  3FP8 I;  3BTM I;  1IRH A;  9PTI A;  3BTF I;  5C67 C;  4BD9 B;  1TOC R;  4ISO B;  1D0D B;  1EAW B;  1F7Z I;  1BTI A;  1BUN B;  1KTH A;  3UIR C;  1JC6 A;  1TAW B;  4Y10 I;  3TGI I;  2PTC I;  1KIG I;  3UOU B;  2FI3 I;  2KAI I;  2ZVX A;  3L3T E;  3P92 E;  1PIT A;  3OFW A;  1BF0 A;  1DEM A;  3M7Q B;  4U30 W;  1G6X A;  1Y62 A;  3BTT I;  1BRC I;  1DEN A;  1BRB I;  1ZR0 B;  3T62 D;  1JV8 A;  3TGJ I;  2UUX A;  1TPA I;  1T7C B;  1T8O B;  2FTL I;  3P95 E;  2FTM B;  6PTI A;  1DTK A;  3AUG A;  2FI4 I;  3LDI A;  3BTD I;  3BTH I;  4NTX B;  3OTJ I;  4Y0Z I;  1YC0 I;  2RA3 C;  1MTN D;  1DTX A;  1FY8 I;  2DDJ A;  1OA5 5;  1P2J I;  3FP7 J;  1TFX C;  4BQD A;  1SHP A;  1UUA A;  1K6U A;  4Y0Y I;  3TPI I;  2CA7 A;  1CA0 D;  1ZJD B;  2ZJX A;  1NAG A;  1T8N B;  2KNT A;  1AAP A;  1KNT A;  3U1J E;  1EJM B;  3BTK I;  1F5R I;  1P2I I;  2M99 A;  5JB4 A;  5JB6 A;  4NTW B;  1B0C A;  4ISL B;  3TGK I;  8PTI A;  1P2N B;  3AUE A;  4PTI A;  3AUD A;  2R9P E;  1D0D A;  2W8X A;  4NTY B;  1CBW D;  3BTW I;  2UUY B;  4U32 X;  3AUI A;  4BNR I;  3WNY A;  1QLQ A;  1OA6 5;  4DG4 C;  2HEX A;  1P2Q B;  2KCR A;  2LFK A;  3BTQ I;  4ISN B;  1FAK I;  1YKT B;  2JOT A;  1YLC B;  1BPI A;  3BTE I;  3CI7 A;  3AUH A;  4WWY C;  1BTH P;  3LDM A;  5JB5 A;  1P2M B;  2IJO I;  1TCP A;  4DTG K;  1UUB A;  1LD6 A;  1YLD B;  1LD5 A;  1AAL A;  1BPT A;  1T8M B;  5JB7 A;  1BHC A;  1ADZ A;  3GYM I;  2ODY E;  1BIK A;  2DDI A;  4TPI I;  3D65 I;  2M01 A;  4WXV C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...