3U1JE

Aprotinin bound to dengue virus protease
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
56
structure length
56
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-bound structures of the dengue virus protease reveal the active conformation
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Dengue virus 3
molecule keywords Serine protease subunit NS2B
total genus 10
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3u1jE00
3BTMI 4BD9B 3TGII 1TAWB 1D0DB 4DTGK 3FP6I 4Y0ZI 1TFXC 3AUGA 1BPIA 4Y0YI 3BYBA 1F5RI 1ZJDB 3M7QB 3BTGI 1BTIA 2UUYB 2IJOI 1T8MB 1TCPA 2FTLI 3P95E 2LFKA 1BZXI 1P2QB 2ZVXA 1BPTA 3BTWI 3LDJA 2DDJA 1EAWB 5PTIA 2W8XA 3BTKI 3BTQI 3LDMA 9PTIA 1UUBA 3U1JE 2HEXA 1F7ZI 1JC6A 1DTXA 1KUNA 1PITA 2DDIA 3BTTI 1OA55 2ZJXA 4NTWB 1KTHA 1MTND 2CA7A 2TGPI 2FI3I 2ODYE 1BHCA 1P2NB 3GYMI 1FANA 4BNRI 4Y11I 1FAKI 1P2JI 1YLCB 3UIRC 2KNTA 1P2KI 1DEMA 1EJMB 3OTJI 4ISNB 4U30W 4Y10I 1IRHA 1DTKA 3AUDA 1UUAA 3AUBA 1K6UA 1QLQA 3TPII 1BF0A 1DENA 1TAPA 2JOTA 2UUXA 3P92E 4TPII 1JV9A 3BTEI 2TPII 1LD6A 1T8LB 1TPAI 2KCRA 3BTHI 1OA65 1ZR0B 3BTDI 1BZ5A 2FI5I 3BTFI 1P2OB 5JB7A 2RA3C 1KIGI 2LFLA 2FTMB 4NTYB 1G6XA 8PTIA 3UOUB 3L3TE 1Y62A 3TGKI 7PTIA 4U32X 5C67C 1YLDB 2FI4I 3L33E 6PTIA 1FY8I 3OFWA 2M01A 2R9PE 1T8NB 1BRCI 3AUCA 3D65I 4WXVC 1T7CB 3AUEA 4DG4C 1CA0D 1TOCR 4PTIA 4BQDA 1JV8A 1BTHP 5JB4A 1D0DA 3WNYA 1BRBI 2J6DA 3LDIA 3TGJI 1CBWD 4ISOB 1YC0I 3T62D 3CI7A 4NTXB 1P2II 3FP8I 1SHPA 1KNTA 1LD5A 1T8OB 2PTCI 3FP7J 1B0CA 1CO7I 3AUHA 1P2MB 4WWYC 1YKTB 5JB5A 4ISLB 1AAPA 2KAII 1BUNB 1AALA 5JB6A 1BIKA 3AUIA 2M99A 1ADZA 1NAGA
chains in the Genus database with same CATH superfamily
3BTMI 4BD9B 3TGII 1TAWB 1D0DB 4DTGK 3FP6I 4Y0ZI 1TFXC 3AUGA 1BPIA 4Y0YI 3BYBA 1F5RI 1ZJDB 3M7QB 3BTGI 1BTIA 2UUYB 2IJOI 1T8MB 1TCPA 2FTLI 3P95E 2LFKA 1BZXI 1P2QB 2ZVXA 1BPTA 3BTWI 3LDJA 2DDJA 1EAWB 5PTIA 2W8XA 3BTKI 3BTQI 3LDMA 9PTIA 1UUBA 3U1JE 2HEXA 1F7ZI 1JC6A 1DTXA 1KUNA 1PITA 2DDIA 3BTTI 1OA55 2ZJXA 4NTWB 1KTHA 1MTND 2CA7A 2TGPI 2FI3I 2ODYE 1BHCA 1P2NB 3GYMI 1FANA 4BNRI 4Y11I 1FAKI 1P2JI 1YLCB 3UIRC 2KNTA 1P2KI 1DEMA 1EJMB 3OTJI 4ISNB 4U30W 4Y10I 1IRHA 1DTKA 3AUDA 1UUAA 3AUBA 1K6UA 1QLQA 3TPII 1BF0A 1DENA 1TAPA 2JOTA 2UUXA 3P92E 4TPII 1JV9A 3BTEI 2TPII 1LD6A 1T8LB 1TPAI 2KCRA 3BTHI 1OA65 1ZR0B 3BTDI 1BZ5A 2FI5I 3BTFI 1P2OB 5JB7A 2RA3C 1KIGI 2LFLA 2FTMB 4NTYB 1G6XA 8PTIA 3UOUB 3L3TE 1Y62A 3TGKI 7PTIA 4U32X 5C67C 1YLDB 2FI4I 3L33E 6PTIA 1FY8I 3OFWA 2M01A 2R9PE 1T8NB 1BRCI 3AUCA 3D65I 4WXVC 1T7CB 3AUEA 4DG4C 1CA0D 1TOCR 4PTIA 4BQDA 1JV8A 1BTHP 5JB4A 1D0DA 3WNYA 1BRBI 2J6DA 3LDIA 3TGJI 1CBWD 4ISOB 1YC0I 3T62D 3CI7A 4NTXB 1P2II 3FP8I 1SHPA 1KNTA 1LD5A 1T8OB 2PTCI 3FP7J 1B0CA 1CO7I 3AUHA 1P2MB 4WWYC 1YKTB 5JB5A 4ISLB 1AAPA 2KAII 1BUNB 1AALA 5JB6A 1BIKA 3AUIA 2M99A 1ADZA 1NAGA
chains in the Genus database with same CATH topology
3BTMI 4BD9B 3TGII 1TAWB 1D0DB 4DTGK 3FP6I 4Y0ZI 1TFXC 3AUGA 1BPIA 4Y0YI 3BYBA 1F5RI 1ZJDB 3M7QB 3BTGI 1BTIA 2UUYB 2IJOI 1T8MB 1TCPA 2FTLI 3P95E 2LFKA 1BZXI 1P2QB 2ZVXA 1BPTA 3BTWI 3LDJA 2DDJA 1EAWB 5PTIA 2W8XA 3BTKI 3BTQI 3LDMA 9PTIA 1UUBA 3U1JE 2HEXA 1F7ZI 1JC6A 1DTXA 1KUNA 1PITA 2DDIA 3BTTI 1OA55 2ZJXA 4NTWB 1KTHA 1MTND 2CA7A 2TGPI 2FI3I 2ODYE 1BHCA 1P2NB 3GYMI 1FANA 4BNRI 4Y11I 1FAKI 1P2JI 1YLCB 3UIRC 2KNTA 1P2KI 1DEMA 1EJMB 3OTJI 4ISNB 4U30W 4Y10I 1IRHA 1DTKA 3AUDA 1UUAA 3AUBA 1K6UA 1QLQA 3TPII 1BF0A 1DENA 1TAPA 2JOTA 2UUXA 3P92E 4TPII 1JV9A 3BTEI 2TPII 1LD6A 1T8LB 1TPAI 2KCRA 3BTHI 1OA65 1ZR0B 3BTDI 1BZ5A 2FI5I 3BTFI 1P2OB 5JB7A 2RA3C 1KIGI 2LFLA 2FTMB 4NTYB 1G6XA 8PTIA 3UOUB 3L3TE 1Y62A 3TGKI 7PTIA 4U32X 5C67C 1YLDB 2FI4I 3L33E 6PTIA 1FY8I 3OFWA 2M01A 2R9PE 1T8NB 1BRCI 3AUCA 3D65I 4WXVC 1T7CB 3AUEA 4DG4C 1CA0D 1TOCR 4PTIA 4BQDA 1JV8A 1BTHP 5JB4A 1D0DA 3WNYA 1BRBI 2J6DA 3LDIA 3TGJI 1CBWD 4ISOB 1YC0I 3T62D 3CI7A 4NTXB 1P2II 3FP8I 1SHPA 1KNTA 1LD5A 1T8OB 2PTCI 3FP7J 1B0CA 1CO7I 3AUHA 1P2MB 4WWYC 1YKTB 5JB5A 4ISLB 1AAPA 2KAII 1BUNB 1AALA 5JB6A 1BIKA 3AUIA 2M99A 1ADZA 1NAGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BTM I;  4BD9 B;  3TGI I;  1TAW B;  1D0D B;  4DTG K;  3FP6 I;  4Y0Z I;  1TFX C;  3AUG A;  1BPI A;  4Y0Y I;  3BYB A;  1F5R I;  1ZJD B;  3M7Q B;  3BTG I;  1BTI A;  2UUY B;  2IJO I;  1T8M B;  1TCP A;  2FTL I;  3P95 E;  2LFK A;  1BZX I;  1P2Q B;  2ZVX A;  1BPT A;  3BTW I;  3LDJ A;  2DDJ A;  1EAW B;  5PTI A;  2W8X A;  3BTK I;  3BTQ I;  3LDM A;  9PTI A;  1UUB A;  3U1J E;  2HEX A;  1F7Z I;  1JC6 A;  1DTX A;  1KUN A;  1PIT A;  2DDI A;  3BTT I;  1OA5 5;  2ZJX A;  4NTW B;  1KTH A;  1MTN D;  2CA7 A;  2TGP I;  2FI3 I;  2ODY E;  1BHC A;  1P2N B;  3GYM I;  1FAN A;  4BNR I;  4Y11 I;  1FAK I;  1P2J I;  1YLC B;  3UIR C;  2KNT A;  1P2K I;  1DEM A;  1EJM B;  3OTJ I;  4ISN B;  4U30 W;  4Y10 I;  1IRH A;  1DTK A;  3AUD A;  1UUA A;  3AUB A;  1K6U A;  1QLQ A;  3TPI I;  1BF0 A;  1DEN A;  1TAP A;  2JOT A;  2UUX A;  3P92 E;  4TPI I;  1JV9 A;  3BTE I;  2TPI I;  1LD6 A;  1T8L B;  1TPA I;  2KCR A;  3BTH I;  1OA6 5;  1ZR0 B;  3BTD I;  1BZ5 A;  2FI5 I;  3BTF I;  1P2O B;  5JB7 A;  2RA3 C;  1KIG I;  2LFL A;  2FTM B;  4NTY B;  1G6X A;  8PTI A;  3UOU B;  3L3T E;  1Y62 A;  3TGK I;  7PTI A;  4U32 X;  5C67 C;  1YLD B;  2FI4 I;  3L33 E;  6PTI A;  1FY8 I;  3OFW A;  2M01 A;  2R9P E;  1T8N B;  1BRC I;  3AUC A;  3D65 I;  4WXV C;  1T7C B;  3AUE A;  4DG4 C;  1CA0 D;  1TOC R;  4PTI A;  4BQD A;  1JV8 A;  1BTH P;  5JB4 A;  1D0D A;  3WNY A;  1BRB I;  2J6D A;  3LDI A;  3TGJ I;  1CBW D;  4ISO B;  1YC0 I;  3T62 D;  3CI7 A;  4NTX B;  1P2I I;  3FP8 I;  1SHP A;  1KNT A;  1LD5 A;  1T8O B;  2PTC I;  3FP7 J;  1B0C A;  1CO7 I;  3AUH A;  1P2M B;  4WWY C;  1YKT B;  5JB5 A;  4ISL B;  1AAP A;  2KAI I;  1BUN B;  1AAL A;  5JB6 A;  1BIK A;  3AUI A;  2M99 A;  1ADZ A;  1NAG A; 
#chains in the Genus database with same CATH topology
 3BTM I;  4BD9 B;  3TGI I;  1TAW B;  1D0D B;  4DTG K;  3FP6 I;  4Y0Z I;  1TFX C;  3AUG A;  1BPI A;  4Y0Y I;  3BYB A;  1F5R I;  1ZJD B;  3M7Q B;  3BTG I;  1BTI A;  2UUY B;  2IJO I;  1T8M B;  1TCP A;  2FTL I;  3P95 E;  2LFK A;  1BZX I;  1P2Q B;  2ZVX A;  1BPT A;  3BTW I;  3LDJ A;  2DDJ A;  1EAW B;  5PTI A;  2W8X A;  3BTK I;  3BTQ I;  3LDM A;  9PTI A;  1UUB A;  3U1J E;  2HEX A;  1F7Z I;  1JC6 A;  1DTX A;  1KUN A;  1PIT A;  2DDI A;  3BTT I;  1OA5 5;  2ZJX A;  4NTW B;  1KTH A;  1MTN D;  2CA7 A;  2TGP I;  2FI3 I;  2ODY E;  1BHC A;  1P2N B;  3GYM I;  1FAN A;  4BNR I;  4Y11 I;  1FAK I;  1P2J I;  1YLC B;  3UIR C;  2KNT A;  1P2K I;  1DEM A;  1EJM B;  3OTJ I;  4ISN B;  4U30 W;  4Y10 I;  1IRH A;  1DTK A;  3AUD A;  1UUA A;  3AUB A;  1K6U A;  1QLQ A;  3TPI I;  1BF0 A;  1DEN A;  1TAP A;  2JOT A;  2UUX A;  3P92 E;  4TPI I;  1JV9 A;  3BTE I;  2TPI I;  1LD6 A;  1T8L B;  1TPA I;  2KCR A;  3BTH I;  1OA6 5;  1ZR0 B;  3BTD I;  1BZ5 A;  2FI5 I;  3BTF I;  1P2O B;  5JB7 A;  2RA3 C;  1KIG I;  2LFL A;  2FTM B;  4NTY B;  1G6X A;  8PTI A;  3UOU B;  3L3T E;  1Y62 A;  3TGK I;  7PTI A;  4U32 X;  5C67 C;  1YLD B;  2FI4 I;  3L33 E;  6PTI A;  1FY8 I;  3OFW A;  2M01 A;  2R9P E;  1T8N B;  1BRC I;  3AUC A;  3D65 I;  4WXV C;  1T7C B;  3AUE A;  4DG4 C;  1CA0 D;  1TOC R;  4PTI A;  4BQD A;  1JV8 A;  1BTH P;  5JB4 A;  1D0D A;  3WNY A;  1BRB I;  2J6D A;  3LDI A;  3TGJ I;  1CBW D;  4ISO B;  1YC0 I;  3T62 D;  3CI7 A;  4NTX B;  1P2I I;  3FP8 I;  1SHP A;  1KNT A;  1LD5 A;  1T8O B;  2PTC I;  3FP7 J;  1B0C A;  1CO7 I;  3AUH A;  1P2M B;  4WWY C;  1YKT B;  5JB5 A;  4ISL B;  1AAP A;  2KAI I;  1BUN B;  1AAL A;  5JB6 A;  1BIK A;  3AUI A;  2M99 A;  1ADZ A;  1NAG A; 
#chains in the Genus database with same CATH homology
 3BTM I;  4BD9 B;  3TGI I;  1TAW B;  1D0D B;  4DTG K;  3FP6 I;  4Y0Z I;  1TFX C;  3AUG A;  1BPI A;  4Y0Y I;  3BYB A;  1F5R I;  1ZJD B;  3M7Q B;  3BTG I;  1BTI A;  2UUY B;  2IJO I;  1T8M B;  1TCP A;  2FTL I;  3P95 E;  2LFK A;  1BZX I;  1P2Q B;  2ZVX A;  1BPT A;  3BTW I;  3LDJ A;  2DDJ A;  1EAW B;  5PTI A;  2W8X A;  3BTK I;  3BTQ I;  3LDM A;  9PTI A;  1UUB A;  3U1J E;  2HEX A;  1F7Z I;  1JC6 A;  1DTX A;  1KUN A;  1PIT A;  2DDI A;  3BTT I;  1OA5 5;  2ZJX A;  4NTW B;  1KTH A;  1MTN D;  2CA7 A;  2TGP I;  2FI3 I;  2ODY E;  1BHC A;  1P2N B;  3GYM I;  1FAN A;  4BNR I;  4Y11 I;  1FAK I;  1P2J I;  1YLC B;  3UIR C;  2KNT A;  1P2K I;  1DEM A;  1EJM B;  3OTJ I;  4ISN B;  4U30 W;  4Y10 I;  1IRH A;  1DTK A;  3AUD A;  1UUA A;  3AUB A;  1K6U A;  1QLQ A;  3TPI I;  1BF0 A;  1DEN A;  1TAP A;  2JOT A;  2UUX A;  3P92 E;  4TPI I;  1JV9 A;  3BTE I;  2TPI I;  1LD6 A;  1T8L B;  1TPA I;  2KCR A;  3BTH I;  1OA6 5;  1ZR0 B;  3BTD I;  1BZ5 A;  2FI5 I;  3BTF I;  1P2O B;  5JB7 A;  2RA3 C;  1KIG I;  2LFL A;  2FTM B;  4NTY B;  1G6X A;  8PTI A;  3UOU B;  3L3T E;  1Y62 A;  3TGK I;  7PTI A;  4U32 X;  5C67 C;  1YLD B;  2FI4 I;  3L33 E;  6PTI A;  1FY8 I;  3OFW A;  2M01 A;  2R9P E;  1T8N B;  1BRC I;  3AUC A;  3D65 I;  4WXV C;  1T7C B;  3AUE A;  4DG4 C;  1CA0 D;  1TOC R;  4PTI A;  4BQD A;  1JV8 A;  1BTH P;  5JB4 A;  1D0D A;  3WNY A;  1BRB I;  2J6D A;  3LDI A;  3TGJ I;  1CBW D;  4ISO B;  1YC0 I;  3T62 D;  3CI7 A;  4NTX B;  1P2I I;  3FP8 I;  1SHP A;  1KNT A;  1LD5 A;  1T8O B;  2PTC I;  3FP7 J;  1B0C A;  1CO7 I;  3AUH A;  1P2M B;  4WWY C;  1YKT B;  5JB5 A;  4ISL B;  1AAP A;  2KAI I;  1BUN B;  1AAL A;  5JB6 A;  1BIK A;  3AUI A;  2M99 A;  1ADZ A;  1NAG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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