3V8XA

The crystal structure of transferrin binding protein a (tbpa) from neisserial meningitidis serogroup b in complex with full length human transferrin
Total Genus 225
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
225
sequence length
862
structure length
853
Chain Sequence
EVTGLGKLVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDSSNYAYFIVKEECKNGSYETCKANPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANKKQAGSLPGNGKYAGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGVGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDKIRHNLSVNLGFDRFGSNLRHQDYYYQHANRAYSSNTPPQNNGKKISPNGSETSPYWVTIGRGNVVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQSARITGINILGKIDWNGVWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEYKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for iron piracy by pathogenic Neisseria.
pubmed doi rcsb
molecule tags Membrane protein/metal transport
source organism Neisseria meningitidis serogroup b
molecule keywords Transferrin-binding protein 1
total genus 225
structure length 853
sequence length 862
ec nomenclature
pdb deposition date 2011-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 3v8xA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 3v8xA01
3EFMA 1KMPA 4RDTA 2HDFA 1NQEA 1QFFA 4AIPA 1FI1A 1QJQA 2HDIA 2W6TA 1FEPA 2W75A 1QFGA 3V89A 1UJWA 3M8BA 2W6UA 3RGMA 1BY3A 4RDRA 3CSLA 1KMOA 2W78A 1XKHA 4B7OA 3RGNA 5FOKA 2YSUA 3FHHA 2FCPA 2IAHA 2W76A 1NQFA 3QLBA 3V8XA 1NQHA 1NQGA 3M8DA 1PO0A 2GRXA 4CU4A 1PO3A 3CSNA 2O5PA 4EPAA 1PNZA 2W16A 1FCPA 1BY5A 3DDRA 2W77A 1XKWA 2GSKA 4AIQA 1QKCA 2GUFA
chains in the Genus database with same CATH superfamily
3EFMA 1KMPA 4RDTA 1MALA 1NQEA 2HDFA 1QFFA 2GSKA 1FI1A 1MPMA 1OH2P 1QJQA 2HDIA 4AIPA 2W6TA 1FEPA 2W75A 1MPNA 1QFGA 3V89A 1UJWA 1A0TP 1MPOA 3M8BA 2MPRA 2W6UA 1BY3A 3RGMA 4RDRA 3CSLA 1KMOA 2W78A 1XKHA 1A0SP 4B7OA 3RGNA 5FOKA 2YSUA 3FHHA 1MPQA 2IAHA 2W76A 1NQFA 3QLBA 3V8XA 1NQHA 1NQGA 3M8DA 1JBIA 1PO0A 2GRXA 4CU4A 1PO3A 3CSNA 2O5PA 1AF6A 4EPAA 1PNZA 2W16A 1FCPA 1OH2Q 1BY5A 1MPRA 3DDRA 2W77A 1XKWA 2FCPA 4AIQA 1QKCA 2GUFA
chains in the Genus database with same CATH topology
3EFMA 1KMPA 4RDTA 2HDFA 1NQEA 1QFFA 4AIPA 1FI1A 1QJQA 2HDIA 2W6TA 1FEPA 2W75A 1QFGA 3V89A 1UJWA 3M8BA 2W6UA 3RGMA 1BY3A 4RDRA 3CSLA 1KMOA 2W78A 1XKHA 4B7OA 3RGNA 5FOKA 2YSUA 3FHHA 2FCPA 2IAHA 2W76A 1NQFA 3QLBA 3V8XA 1NQHA 1NQGA 3M8DA 1PO0A 2GRXA 4CU4A 1PO3A 3CSNA 2O5PA 4EPAA 1PNZA 2W16A 1FCPA 1BY5A 3DDRA 2W77A 1XKWA 2GSKA 4AIQA 1QKCA 2GUFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EFM A;  1KMP A;  4RDT A;  2HDF A;  1NQE A;  1QFF A;  4AIP A;  1FI1 A;  1QJQ A;  2HDI A;  2W6T A;  1FEP A;  2W75 A;  1QFG A;  3V89 A;  1UJW A;  3M8B A;  2W6U A;  3RGM A;  1BY3 A;  4RDR A;  3CSL A;  1KMO A;  2W78 A;  1XKH A;  4B7O A;  3RGN A;  5FOK A;  2YSU A;  3FHH A;  2FCP A;  2IAH A;  2W76 A;  1NQF A;  3QLB A;  3V8X A;  1NQH A;  1NQG A;  3M8D A;  1PO0 A;  2GRX A;  4CU4 A;  1PO3 A;  3CSN A;  2O5P A;  4EPA A;  1PNZ A;  2W16 A;  1FCP A;  1BY5 A;  3DDR A;  2W77 A;  1XKW A;  2GSK A;  4AIQ A;  1QKC A;  2GUF A; 
#chains in the Genus database with same CATH topology
 3EFM A;  1KMP A;  4RDT A;  1MAL A;  1NQE A;  2HDF A;  1QFF A;  2GSK A;  1FI1 A;  1MPM A;  1OH2 P;  1QJQ A;  2HDI A;  4AIP A;  2W6T A;  1FEP A;  2W75 A;  1MPN A;  1QFG A;  3V89 A;  1UJW A;  1A0T P;  1MPO A;  3M8B A;  2MPR A;  2W6U A;  1BY3 A;  3RGM A;  4RDR A;  3CSL A;  1KMO A;  2W78 A;  1XKH A;  1A0S P;  4B7O A;  3RGN A;  5FOK A;  2YSU A;  3FHH A;  1MPQ A;  2IAH A;  2W76 A;  1NQF A;  3QLB A;  3V8X A;  1NQH A;  1NQG A;  3M8D A;  1JBI A;  1PO0 A;  2GRX A;  4CU4 A;  1PO3 A;  3CSN A;  2O5P A;  1AF6 A;  4EPA A;  1PNZ A;  2W16 A;  1FCP A;  1OH2 Q;  1BY5 A;  1MPR A;  3DDR A;  2W77 A;  1XKW A;  2FCP A;  4AIQ A;  1QKC A;  2GUF A; 
#chains in the Genus database with same CATH homology
 3EFM A;  1KMP A;  4RDT A;  2HDF A;  1NQE A;  1QFF A;  4AIP A;  1FI1 A;  1QJQ A;  2HDI A;  2W6T A;  1FEP A;  2W75 A;  1QFG A;  3V89 A;  1UJW A;  3M8B A;  2W6U A;  3RGM A;  1BY3 A;  4RDR A;  3CSL A;  1KMO A;  2W78 A;  1XKH A;  4B7O A;  3RGN A;  5FOK A;  2YSU A;  3FHH A;  2FCP A;  2IAH A;  2W76 A;  1NQF A;  3QLB A;  3V8X A;  1NQH A;  1NQG A;  3M8D A;  1PO0 A;  2GRX A;  4CU4 A;  1PO3 A;  3CSN A;  2O5P A;  4EPA A;  1PNZ A;  2W16 A;  1FCP A;  1BY5 A;  3DDR A;  2W77 A;  1XKW A;  2GSK A;  4AIQ A;  1QKC A;  2GUF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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