4A3CF

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid
Total Genus 29
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 29
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4a3cF00
4A3EF 1I3QF 3S14F 3S16F 1SFOF 4A3CF 4A3GF 4MQ9E 5TMCE 3I4NF 1TWHF 4G7HE 4GZYE 1YNJK 4Y52F 5E18E 2VUMF 5M5XF 4YFNE 2JA6F 4YFXE 1ZYRE 3FKIF 3S1QF 4A3MF 1R9TF 4BY1F 4MEYE 4LK1E 3S1MF 4A93F 5M3FF 1SMYE 4OIRE 4G7OE 2E2HF 5C4XF 2JA7F 3CQZF 5M3MF 4C3IF 3HOZF 4C2MF 3I4MF 2PMZK 4XLPE 4LK0E 1TWAF 4BY7F 5TMFE 3RZDF 4OIOE 4A3LF 3H0GF 5BYHE 2NVYF 5IP7F 3S1NF 2E2IF 3S17F 2A6HE 4A3FF 4YG2E 3K7AF 3M4OF 4XSXE 2JA5F 2A69E 2O5IE 3HOUF 5FLMF 4BXXF 5D4CE 2CW0E 4OIQE 4A3DF 4A3KF 2R92F 3GTPF 1I50F 4G7ZE 2A6EE 5M5YF 1TWCF 3GTGF 3HKZK 3S2DF 4LLGE 5IYCF 1WCMF 1I6VE 4A3IF 2JA8F 5IPLE 3H3VG 4Q5SE 4LJZE 3HOYF 5C4JF 5M5WF 4KMUE 4XLNE 1Y1WF 2O5JE 4C3HF 4Q4ZE 3S1RF 2NVQF 1TWGF 1K83F 4Y7NF 5D4EE 1QKLA 3PO3F 4X6AF 1HQME 3GTLF 2R93F 5E17E 4ZH4E 4XSZE 5IP9F 4C3JF 2A68E 3M3YF 3RZOF 4OIPE 2Y0SI 5IYDF 5FJ8F 4KN7E 4OINE 3WODE 3GTOF 3HOVF 2B63F 4BBRF 2R7ZF 1YNNK 2WAQK 5IYBF 3GTMF 2YU9F 4YFKE 5C3EF 4KN4E 3GTKF 3GTJF 3GTQF 1Y1VF 3S2HF 2NVTF 4A3BF 5D4DE 3DXJE 1I6HF 3PO2F 1TWFF 2BE5E 2NVXF 2E2JF 4AYBK 3HOWF 3HOXF 4JK1E 4MEXE 3S15F 2WB1I 4BBSF 1IW7E 4A3JF 5C44F 2PPBE 3EQLE
chains in the Genus database with same CATH superfamily
4A3EF 4BBSE 1I3QF 4A3JE 5C44E 3S14F 3S16F 3M3YE 1SFOF 3RZOE 4A3CF 4A3GF 4MQ9E 2WAQH 5TMCE 4A3EE 3I4NF 3S14E 1TWHF 4G7HE 1SFOE 4GZYE 1YNJK 2WB1H 4A3CE 4Y52F 5E18E 2VUMF 5M5XF 3I4NE 4YFNE 2JA6F 1TWHE 4YFXE 5C3EE 1ZYRE 3FKIF 3S1QF 4A3MF 1R9TF 4BY1F 5M5XE 3GTQE 4MEYE 4LK1E 3S1MF 2JA6E 5M3FF 1SMYE 4OIRE 4A93F 4G7OE 3FKIE 4AYBH 4A3ME 2E2HF 3CQZF 5M3MF 4C3IF 1R9TE 4BY1E 2JA7F 3HOZF 4C2MF 4A93E 2PMZH 3I4MF 2PMZK 2E2HE 5C4XE 3CQZE 4C3IE 3HOWE 3HOZE 4XLPE 4C2ME 3S15E 3I4ME 4LK0E 1TWAF 4BY7F 5TMFE 3RZDF 4OIOE 4A3LF 3H0GF 5BYHE 1I3QE 2NVYF 5IP7F 3S1QE 3S1NF 3S16E 2E2IF 3S17F 1TWAE 3RZDE 4A3LE 4BY7E 2A6HE 4A3GE 3H0GE 4A3FF 2NVYE 4YG2E 5IP7E 3S1NE 2E2IE 3K7AF 3S17E 3M4OF 4XSXE 4Y52E 2VUME 4A3FE 2JA5F 2A69E 2O5IE 3HOUF 3M4OE 5FLMF 4BXXF 2JA5E 3S1ME 5D4CE 2CW0E 4OIQE 5M3FE 4A3DF 4A3KF 2R92F 3GTPF 1I50F 5FLME 4G7ZE 5M3ME 2A6EE 2JA7E 4BXXE 5M5YF 1TWCF 4A3DE 3HKZH 4A3KE 3GTGF 1DZFA 1I50E 3HKZK 3GTPE 2R92E 5C4XF 3H3VF 3S2DF 5M5YE 4LLGE 1TWCE 5IYCF 3GTGE 1WCMF 1I6VE 2KRXA 4A3IF 2JA8F 3H3VG 5IPLE 4Q5SE 4LJZE 3HOYF 5C4JF 3S2DE 5M5WF 4KMUE 4XLNE 1Y1WF 1WCME 4A3IE 2O5JE 4C3HF 1EIKA 4Q4ZE 3S1RF 3HOYE 2NVQF 1TWGF 1K83F 4Y7NF 5M5WE 1QKLA 5D4EE 1Y1WE 3PO3F 4C3HE 4X6AF 1HQME 3GTLF 2R93F 3S1RE 5E17E 4ZH4E 3K7AE 2NVQE 3PO3E 1K83E 4XSZE 5IP9F 4C3JF 4Y7NE 2A68E 3M3YF 3RZOF 4OIPE 2Y0SI 5IYDF 5FJ8F 3GTLE 4KN7E 4OINE 3HOUE 2R93E 5IP9E 4C3JE 3WODE 3GTOF 3HOVF 2B63F 4BBRF 5IYDE 5FJ8E 2R7ZF 4X6AE 1YNNK 2WAQK 5IYBF 3GTMF 2YU9F 4YFKE 3HOVE 3GTOE 5C3EF 2B63E 4BBRE 2R7ZE 4KN4E 3GTKF 5IYBE 3GTJF 3GTME 1Y1VF 2YU9E 2Y0SH 3GTQF 3S2HF 2NVTF 4A3BF 5D4DE 5IYCE 3GTKE 3DXJE 3GTJE 1I6HF 1Y1VE 2JA8E 1TWFF 2BE5E 2NVXF 3PO2F 3S2HE 2NVTE 4A3BE 5C4JE 2E2JF 4AYBK 3HOWF 1I6HE 3PO2E 1TWFE 2NVXE 3HOXF 4JK1E 4MEXE 3S15F 1TWGE 2WB1I 2E2JE 1IW7E 4A3JF 4BBSF 5C44F 4QIWH 4QIWK 2PPBE 3HOXE 3EQLE
chains in the Genus database with same CATH topology
4A3EF 1I3QF 3S14F 3S16F 1SFOF 4A3CF 4A3GF 4MQ9E 5TMCE 3I4NF 1TWHF 4G7HE 4GZYE 1YNJK 4Y52F 5E18E 2VUMF 5M5XF 4YFNE 2JA6F 4YFXE 1ZYRE 3FKIF 3S1QF 4A3MF 1R9TF 4BY1F 4MEYE 4LK1E 3S1MF 4A93F 5M3FF 1SMYE 4OIRE 4G7OE 2E2HF 5C4XF 2JA7F 3CQZF 5M3MF 4C3IF 3HOZF 4C2MF 3I4MF 2PMZK 4XLPE 4LK0E 1TWAF 4BY7F 5TMFE 3RZDF 4OIOE 4A3LF 3H0GF 5BYHE 2NVYF 5IP7F 3S1NF 2E2IF 3S17F 2A6HE 4A3FF 4YG2E 3K7AF 3M4OF 4XSXE 2JA5F 2A69E 2O5IE 3HOUF 5FLMF 4BXXF 5D4CE 2CW0E 4OIQE 4A3DF 4A3KF 2R92F 3GTPF 1I50F 4G7ZE 2A6EE 5M5YF 1TWCF 3GTGF 3HKZK 3S2DF 4LLGE 5IYCF 1WCMF 1I6VE 2KRXA 4A3IF 2JA8F 3H3VG 5IPLE 4Q5SE 4LJZE 3HOYF 5C4JF 5M5WF 4KMUE 4XLNE 1Y1WF 2O5JE 4C3HF 4Q4ZE 3S1RF 2NVQF 1TWGF 1K83F 4Y7NF 5D4EE 1QKLA 3PO3F 4X6AF 1HQME 3GTLF 2R93F 5E17E 4ZH4E 4XSZE 5IP9F 4C3JF 2A68E 3M3YF 3RZOF 4OIPE 2Y0SI 5IYDF 5FJ8F 4KN7E 4OINE 3WODE 3GTOF 3HOVF 2B63F 4BBRF 2R7ZF 1YNNK 2WAQK 5IYBF 3GTMF 2YU9F 4YFKE 5C3EF 4KN4E 3GTKF 3GTJF 3GTQF 1Y1VF 3S2HF 2NVTF 4A3BF 5D4DE 3DXJE 1I6HF 3PO2F 1TWFF 2BE5E 2NVXF 2E2JF 4AYBK 3HOWF 3HOXF 4JK1E 4MEXE 3S15F 2WB1I 4BBSF 1IW7E 4A3JF 5C44F 4QIWK 2PPBE 3EQLE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3E F;  1I3Q F;  3S14 F;  3S16 F;  1SFO F;  4A3C F;  4A3G F;  4MQ9 E;  5TMC E;  3I4N F;  1TWH F;  4G7H E;  4GZY E;  1YNJ K;  4Y52 F;  5E18 E;  2VUM F;  5M5X F;  4YFN E;  2JA6 F;  4YFX E;  1ZYR E;  3FKI F;  3S1Q F;  4A3M F;  1R9T F;  4BY1 F;  4MEY E;  4LK1 E;  3S1M F;  4A93 F;  5M3F F;  1SMY E;  4OIR E;  4G7O E;  2E2H F;  5C4X F;  2JA7 F;  3CQZ F;  5M3M F;  4C3I F;  3HOZ F;  4C2M F;  3I4M F;  2PMZ K;  4XLP E;  4LK0 E;  1TWA F;  4BY7 F;  5TMF E;  3RZD F;  4OIO E;  4A3L F;  3H0G F;  5BYH E;  2NVY F;  5IP7 F;  3S1N F;  2E2I F;  3S17 F;  2A6H E;  4A3F F;  4YG2 E;  3K7A F;  3M4O F;  4XSX E;  2JA5 F;  2A69 E;  2O5I E;  3HOU F;  5FLM F;  4BXX F;  5D4C E;  2CW0 E;  4OIQ E;  4A3D F;  4A3K F;  2R92 F;  3GTP F;  1I50 F;  4G7Z E;  2A6E E;  5M5Y F;  1TWC F;  3GTG F;  3HKZ K;  3S2D F;  4LLG E;  5IYC F;  1WCM F;  1I6V E;  4A3I F;  2JA8 F;  5IPL E;  3H3V G;  4Q5S E;  4LJZ E;  3HOY F;  5C4J F;  5M5W F;  4KMU E;  4XLN E;  1Y1W F;  2O5J E;  4C3H F;  4Q4Z E;  3S1R F;  2NVQ F;  1TWG F;  1K83 F;  4Y7N F;  5D4E E;  1QKL A;  3PO3 F;  4X6A F;  1HQM E;  3GTL F;  2R93 F;  5E17 E;  4ZH4 E;  4XSZ E;  5IP9 F;  4C3J F;  2A68 E;  3M3Y F;  3RZO F;  4OIP E;  2Y0S I;  5IYD F;  5FJ8 F;  4KN7 E;  4OIN E;  3WOD E;  3GTO F;  3HOV F;  2B63 F;  4BBR F;  2R7Z F;  1YNN K;  2WAQ K;  5IYB F;  3GTM F;  2YU9 F;  4YFK E;  5C3E F;  4KN4 E;  3GTK F;  3GTJ F;  3GTQ F;  1Y1V F;  3S2H F;  2NVT F;  4A3B F;  5D4D E;  3DXJ E;  1I6H F;  3PO2 F;  1TWF F;  2BE5 E;  2NVX F;  2E2J F;  4AYB K;  3HOW F;  3HOX F;  4JK1 E;  4MEX E;  3S15 F;  2WB1 I;  4BBS F;  1IW7 E;  4A3J F;  5C44 F;  2PPB E;  3EQL E; 
#chains in the Genus database with same CATH topology
 4A3E F;  4BBS E;  1I3Q F;  4A3J E;  5C44 E;  3S14 F;  3S16 F;  3M3Y E;  1SFO F;  3RZO E;  4A3C F;  4A3G F;  4MQ9 E;  2WAQ H;  5TMC E;  4A3E E;  3I4N F;  3S14 E;  1TWH F;  4G7H E;  1SFO E;  4GZY E;  1YNJ K;  2WB1 H;  4A3C E;  4Y52 F;  5E18 E;  2VUM F;  5M5X F;  3I4N E;  4YFN E;  2JA6 F;  1TWH E;  4YFX E;  5C3E E;  1ZYR E;  3FKI F;  3S1Q F;  4A3M F;  1R9T F;  4BY1 F;  5M5X E;  3GTQ E;  4MEY E;  4LK1 E;  3S1M F;  2JA6 E;  5M3F F;  1SMY E;  4OIR E;  4A93 F;  4G7O E;  3FKI E;  4AYB H;  4A3M E;  2E2H F;  3CQZ F;  5M3M F;  4C3I F;  1R9T E;  4BY1 E;  2JA7 F;  3HOZ F;  4C2M F;  4A93 E;  2PMZ H;  3I4M F;  2PMZ K;  2E2H E;  5C4X E;  3CQZ E;  4C3I E;  3HOW E;  3HOZ E;  4XLP E;  4C2M E;  3S15 E;  3I4M E;  4LK0 E;  1TWA F;  4BY7 F;  5TMF E;  3RZD F;  4OIO E;  4A3L F;  3H0G F;  5BYH E;  1I3Q E;  2NVY F;  5IP7 F;  3S1Q E;  3S1N F;  3S16 E;  2E2I F;  3S17 F;  1TWA E;  3RZD E;  4A3L E;  4BY7 E;  2A6H E;  4A3G E;  3H0G E;  4A3F F;  2NVY E;  4YG2 E;  5IP7 E;  3S1N E;  2E2I E;  3K7A F;  3S17 E;  3M4O F;  4XSX E;  4Y52 E;  2VUM E;  4A3F E;  2JA5 F;  2A69 E;  2O5I E;  3HOU F;  3M4O E;  5FLM F;  4BXX F;  2JA5 E;  3S1M E;  5D4C E;  2CW0 E;  4OIQ E;  5M3F E;  4A3D F;  4A3K F;  2R92 F;  3GTP F;  1I50 F;  5FLM E;  4G7Z E;  5M3M E;  2A6E E;  2JA7 E;  4BXX E;  5M5Y F;  1TWC F;  4A3D E;  3HKZ H;  4A3K E;  3GTG F;  1DZF A;  1I50 E;  3HKZ K;  3GTP E;  2R92 E;  5C4X F;  3H3V F;  3S2D F;  5M5Y E;  4LLG E;  1TWC E;  5IYC F;  3GTG E;  1WCM F;  1I6V E;  2KRX A;  4A3I F;  2JA8 F;  3H3V G;  5IPL E;  4Q5S E;  4LJZ E;  3HOY F;  5C4J F;  3S2D E;  5M5W F;  4KMU E;  4XLN E;  1Y1W F;  1WCM E;  4A3I E;  2O5J E;  4C3H F;  1EIK A;  4Q4Z E;  3S1R F;  3HOY E;  2NVQ F;  1TWG F;  1K83 F;  4Y7N F;  5M5W E;  1QKL A;  5D4E E;  1Y1W E;  3PO3 F;  4C3H E;  4X6A F;  1HQM E;  3GTL F;  2R93 F;  3S1R E;  5E17 E;  4ZH4 E;  3K7A E;  2NVQ E;  3PO3 E;  1K83 E;  4XSZ E;  5IP9 F;  4C3J F;  4Y7N E;  2A68 E;  3M3Y F;  3RZO F;  4OIP E;  2Y0S I;  5IYD F;  5FJ8 F;  3GTL E;  4KN7 E;  4OIN E;  3HOU E;  2R93 E;  5IP9 E;  4C3J E;  3WOD E;  3GTO F;  3HOV F;  2B63 F;  4BBR F;  5IYD E;  5FJ8 E;  2R7Z F;  4X6A E;  1YNN K;  2WAQ K;  5IYB F;  3GTM F;  2YU9 F;  4YFK E;  3HOV E;  3GTO E;  5C3E F;  2B63 E;  4BBR E;  2R7Z E;  4KN4 E;  3GTK F;  5IYB E;  3GTJ F;  3GTM E;  1Y1V F;  2YU9 E;  2Y0S H;  3GTQ F;  3S2H F;  2NVT F;  4A3B F;  5D4D E;  5IYC E;  3GTK E;  3DXJ E;  3GTJ E;  1I6H F;  1Y1V E;  2JA8 E;  1TWF F;  2BE5 E;  2NVX F;  3PO2 F;  3S2H E;  2NVT E;  4A3B E;  5C4J E;  2E2J F;  4AYB K;  3HOW F;  1I6H E;  3PO2 E;  1TWF E;  2NVX E;  3HOX F;  4JK1 E;  4MEX E;  3S15 F;  1TWG E;  2WB1 I;  2E2J E;  1IW7 E;  4A3J F;  4BBS F;  5C44 F;  4QIW H;  4QIW K;  2PPB E;  3HOX E;  3EQL E; 
#chains in the Genus database with same CATH homology
 4A3E F;  1I3Q F;  3S14 F;  3S16 F;  1SFO F;  4A3C F;  4A3G F;  4MQ9 E;  5TMC E;  3I4N F;  1TWH F;  4G7H E;  4GZY E;  1YNJ K;  4Y52 F;  5E18 E;  2VUM F;  5M5X F;  4YFN E;  2JA6 F;  4YFX E;  1ZYR E;  3FKI F;  3S1Q F;  4A3M F;  1R9T F;  4BY1 F;  4MEY E;  4LK1 E;  3S1M F;  4A93 F;  5M3F F;  1SMY E;  4OIR E;  4G7O E;  2E2H F;  5C4X F;  2JA7 F;  3CQZ F;  5M3M F;  4C3I F;  3HOZ F;  4C2M F;  3I4M F;  2PMZ K;  4XLP E;  4LK0 E;  1TWA F;  4BY7 F;  5TMF E;  3RZD F;  4OIO E;  4A3L F;  3H0G F;  5BYH E;  2NVY F;  5IP7 F;  3S1N F;  2E2I F;  3S17 F;  2A6H E;  4A3F F;  4YG2 E;  3K7A F;  3M4O F;  4XSX E;  2JA5 F;  2A69 E;  2O5I E;  3HOU F;  5FLM F;  4BXX F;  5D4C E;  2CW0 E;  4OIQ E;  4A3D F;  4A3K F;  2R92 F;  3GTP F;  1I50 F;  4G7Z E;  2A6E E;  5M5Y F;  1TWC F;  3GTG F;  3HKZ K;  3S2D F;  4LLG E;  5IYC F;  1WCM F;  1I6V E;  2KRX A;  4A3I F;  2JA8 F;  3H3V G;  5IPL E;  4Q5S E;  4LJZ E;  3HOY F;  5C4J F;  5M5W F;  4KMU E;  4XLN E;  1Y1W F;  2O5J E;  4C3H F;  4Q4Z E;  3S1R F;  2NVQ F;  1TWG F;  1K83 F;  4Y7N F;  5D4E E;  1QKL A;  3PO3 F;  4X6A F;  1HQM E;  3GTL F;  2R93 F;  5E17 E;  4ZH4 E;  4XSZ E;  5IP9 F;  4C3J F;  2A68 E;  3M3Y F;  3RZO F;  4OIP E;  2Y0S I;  5IYD F;  5FJ8 F;  4KN7 E;  4OIN E;  3WOD E;  3GTO F;  3HOV F;  2B63 F;  4BBR F;  2R7Z F;  1YNN K;  2WAQ K;  5IYB F;  3GTM F;  2YU9 F;  4YFK E;  5C3E F;  4KN4 E;  3GTK F;  3GTJ F;  3GTQ F;  1Y1V F;  3S2H F;  2NVT F;  4A3B F;  5D4D E;  3DXJ E;  1I6H F;  3PO2 F;  1TWF F;  2BE5 E;  2NVX F;  2E2J F;  4AYB K;  3HOW F;  3HOX F;  4JK1 E;  4MEX E;  3S15 F;  2WB1 I;  4BBS F;  1IW7 E;  4A3J F;  5C44 F;  4QIW K;  2PPB E;  3EQL E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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