4A3DE

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 68
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3dE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3dE02
2NVXE 4C3IE 2NVYE 3S1NE 5M5WE 3RZDE 5M3FE 1I3QE 5IYDE 3HOVE 3GTJE 4A3KE 2E2HE 3CQZE 3FKIE 5IP9E 1I6HE 2JA7E 5M3ME 2JA8E 1TWFE 1R9TE 2R7ZE 2E2JE 4BBSE 3S1QE 4A3GE 1K83E 3GTLE 2VUME 3S1RE 4A93E 3S1ME 5IYCE 2WAQH 2NVQE 1WCME 4A3EE 2NVTE 5FLME 5FJ8E 3S15E 4QIWH 2YU9E 5C3EE 1I50E 4C2ME 4A3FE 2WB1H 3GTPE 4X6AE 4A3JE 3GTQE 3S2DE 3GTKE 1TWHE 3S17E 4BY7E 5IYBE 3GTGE 4A3CE 2PMZH 2E2IE 2JA6E 3HOUE 5C4JE 3S2HE 3GTOE 3I4NE 1TWGE 3HOYE 5M5XE 3HKZH 5IP7E 5M5YE 4BXXE 3M4OE 4Y52E 2Y0SH 4BBRE 5C44E 2B63E 4C3HE 4A3LE 3PO3E 4AYBH 3H0GE 1Y1WE 1DZFA 1TWCE 3K7AE 4Y7NE 3RZOE 2JA5E 3GTME 1SFOE 1Y1VE 3PO2E 2R93E 4BY1E 3HOWE 3M3YE 4A3BE 2R92E 4A3DE 3S16E 4C3JE 5C4XE 1TWAE 4A3IE 4A3ME 3HOXE 3S14E 1EIKA 3I4ME 3HOZE 3H3VF
chains in the Genus database with same CATH superfamily
2NVXE 4A3JF 2B63F 4MQ9E 4C3IE 1TWHF 4LK1E 4C3HF 2NVYE 3S1NE 4A3LF 4OIQE 5M5WE 4OINE 1QKLA 4JK1E 3RZDE 3GTPF 5M3FE 3H0GF 1Y1WF 1I3QE 5TMFE 1TWCF 3K7AF 5IYDE 3HOVE 3GTJE 4A3KE 2E2HE 4YFXE 3DXJE 4Y7NF 3CQZE 3FKIE 4KN4E 2JA5F 3GTMF 3HOUF 3RZOF 5IP9E 1Y1VF 3PO2F 1I6HE 2R93F 2JA7E 4BY1F 3HOWF 5M3ME 2JA8E 1TWFE 1R9TE 4G7HE 3M3YF 2R7ZE 4LJZE 2R92F 4A3BF 2E2JE 4BBSE 4C3JF 5E18E 3S1QE 3S16F 4A3DF 5C4XF 1TWAF 4A3GE 4KN7E 4A3IF 4A3MF 3HKZK 1K83E 3GTLE 3HOXF 2A68E 2VUME 3S1RE 4A93E 3S1ME 3S14F 2O5JE 5C44F 5IYCE 2WAQH 3HOZF 2NVQE 3PO3F 4OIOE 1WCME 4A3EE 5D4EE 5M5XF 2E2HF 4BXXF 2NVTE 5FLME 4KMUE 4G7ZE 2NVXF 5FJ8E 3S15E 4C3IF 4YFKE 1YNJK 5D4DE 2NVYF 4Q4ZE 4AYBK 4QIWH 5M5WF 2YU9E 3S1NF 5E17E 2WB1I 5C3EE 1I50E 4C2ME 4A3FE 4XSXE 5M3FF 2PMZK 1YNNK 2KRXA 1I3QF 2WB1H 1SFOF 4LLGE 2A6HE 4Q5SE 5IYDF 3GTPE 1ZYRE 4X6AE 3GTJF 4A3JE 3GTQE 3S2DE 3CQZF 3FKIF 4A3KF 3GTKE 1TWHE 5IP9F 3S17E 2CW0E 4BY7E 1I6HF 2JA7F 1I6VE 5IYBE 3GTGE 5M3MF 2JA8F 4A3CE 1TWFF 1R9TF 5IPLE 2PMZH 2R7ZF 2E2JF 2E2IE 2JA6E 4BBSF 2O5IE 3HOUE 5C4JE 1K83F 3GTLF 3S2HE 3I4MF 3GTOE 4MEYE 3S1RF 3I4NE 1HQME 3S1MF 4A93F 1TWGE 3HOYE 5M5XE 5IYCF 4MEXE 3HKZH 5IP7E 1WCMF 5BYHE 4A3EF 4LK0E 4ZH4E 5M5YE 2NVTF 5FLMF 4BXXE 2Y0SI 3M4OE 4OIPE 3S15F 3WODE 4Y52E 2YU9F 2Y0SH 4BBRE 5C44E 4YG2E 3HOVF 2A69E 2B63E 5C3EF 4A3FF 4C3HE 4A3LE 3EQLE 3PO3E 2BE5E 4AYBH 4X6AF 4XLPE 3GTQF 3S2DF 3H0GE 1Y1WE 3GTKF 1DZFA 3S17F 1TWCE 3K7AE 4BY7F 3H3VG 4Y7NE 5IYBF 3GTGF 4XLNE 3RZOE 3S1QF 2JA5E 4A3GF 3GTME 4G7OE 1SFOE 1Y1VE 3PO2E 2R93E 2A6EE 4A3CF 2VUMF 4YFNE 1IW7E 2E2IF 2JA6F 4BY1E 3HOWE 5C4JF 3M3YE 4A3BE 2R92E 4A3DE 5TMCE 2NVQF 3S16E 4C3JE 3GTOF 3S2HF 5C4XE 2PPBE 3I4NF 1TWAE 4A3IE 4A3ME 1TWGF 2WAQK 4OIRE 3HOYF 3HOXE 5FJ8F 4XSZE 4GZYE 5IP7F 5D4CE 3S14E 1EIKA 5M5YF 1I50F 3I4ME 3HOZE 4C2MF 3M4OF 4QIWK 4Y52F 3RZDF 3H3VF 4BBRF 1SMYE
chains in the Genus database with same CATH topology
2NVXE 4C3IE 2NVYE 3S1NE 5M5WE 3RZDE 5M3FE 1I3QE 5IYDE 3HOVE 3GTJE 4A3KE 2E2HE 3CQZE 3FKIE 5IP9E 1I6HE 2JA7E 5M3ME 2JA8E 1TWFE 1R9TE 2R7ZE 2E2JE 4BBSE 3S1QE 4A3GE 1K83E 3GTLE 2VUME 3S1RE 4A93E 3S1ME 5IYCE 2WAQH 2NVQE 1WCME 4A3EE 2NVTE 5FLME 5FJ8E 3S15E 4QIWH 2YU9E 5C3EE 1I50E 4C2ME 4A3FE 2WB1H 3GTPE 4X6AE 4A3JE 3GTQE 3S2DE 3GTKE 1TWHE 3S17E 4BY7E 5IYBE 3GTGE 4A3CE 2PMZH 2E2IE 2JA6E 3HOUE 5C4JE 3S2HE 3GTOE 3I4NE 1TWGE 3HOYE 5M5XE 3HKZH 5IP7E 5M5YE 4BXXE 3M4OE 4Y52E 2Y0SH 4BBRE 5C44E 2B63E 4C3HE 4A3LE 3PO3E 4AYBH 3H0GE 1Y1WE 1DZFA 1TWCE 3K7AE 4Y7NE 3RZOE 2JA5E 3GTME 1SFOE 1Y1VE 3PO2E 2R93E 4BY1E 3HOWE 3M3YE 4A3BE 2R92E 4A3DE 3S16E 4C3JE 5C4XE 1TWAE 4A3IE 4A3ME 3HOXE 3S14E 1EIKA 3I4ME 3HOZE 3H3VF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVX E;  4C3I E;  2NVY E;  3S1N E;  5M5W E;  3RZD E;  5M3F E;  1I3Q E;  5IYD E;  3HOV E;  3GTJ E;  4A3K E;  2E2H E;  3CQZ E;  3FKI E;  5IP9 E;  1I6H E;  2JA7 E;  5M3M E;  2JA8 E;  1TWF E;  1R9T E;  2R7Z E;  2E2J E;  4BBS E;  3S1Q E;  4A3G E;  1K83 E;  3GTL E;  2VUM E;  3S1R E;  4A93 E;  3S1M E;  5IYC E;  2WAQ H;  2NVQ E;  1WCM E;  4A3E E;  2NVT E;  5FLM E;  5FJ8 E;  3S15 E;  4QIW H;  2YU9 E;  5C3E E;  1I50 E;  4C2M E;  4A3F E;  2WB1 H;  3GTP E;  4X6A E;  4A3J E;  3GTQ E;  3S2D E;  3GTK E;  1TWH E;  3S17 E;  4BY7 E;  5IYB E;  3GTG E;  4A3C E;  2PMZ H;  2E2I E;  2JA6 E;  3HOU E;  5C4J E;  3S2H E;  3GTO E;  3I4N E;  1TWG E;  3HOY E;  5M5X E;  3HKZ H;  5IP7 E;  5M5Y E;  4BXX E;  3M4O E;  4Y52 E;  2Y0S H;  4BBR E;  5C44 E;  2B63 E;  4C3H E;  4A3L E;  3PO3 E;  4AYB H;  3H0G E;  1Y1W E;  1DZF A;  1TWC E;  3K7A E;  4Y7N E;  3RZO E;  2JA5 E;  3GTM E;  1SFO E;  1Y1V E;  3PO2 E;  2R93 E;  4BY1 E;  3HOW E;  3M3Y E;  4A3B E;  2R92 E;  4A3D E;  3S16 E;  4C3J E;  5C4X E;  1TWA E;  4A3I E;  4A3M E;  3HOX E;  3S14 E;  1EIK A;  3I4M E;  3HOZ E;  3H3V F; 
#chains in the Genus database with same CATH topology
 2NVX E;  4A3J F;  2B63 F;  4MQ9 E;  4C3I E;  1TWH F;  4LK1 E;  4C3H F;  2NVY E;  3S1N E;  4A3L F;  4OIQ E;  5M5W E;  4OIN E;  1QKL A;  4JK1 E;  3RZD E;  3GTP F;  5M3F E;  3H0G F;  1Y1W F;  1I3Q E;  5TMF E;  1TWC F;  3K7A F;  5IYD E;  3HOV E;  3GTJ E;  4A3K E;  2E2H E;  4YFX E;  3DXJ E;  4Y7N F;  3CQZ E;  3FKI E;  4KN4 E;  2JA5 F;  3GTM F;  3HOU F;  3RZO F;  5IP9 E;  1Y1V F;  3PO2 F;  1I6H E;  2R93 F;  2JA7 E;  4BY1 F;  3HOW F;  5M3M E;  2JA8 E;  1TWF E;  1R9T E;  4G7H E;  3M3Y F;  2R7Z E;  4LJZ E;  2R92 F;  4A3B F;  2E2J E;  4BBS E;  4C3J F;  5E18 E;  3S1Q E;  3S16 F;  4A3D F;  5C4X F;  1TWA F;  4A3G E;  4KN7 E;  4A3I F;  4A3M F;  3HKZ K;  1K83 E;  3GTL E;  3HOX F;  2A68 E;  2VUM E;  3S1R E;  4A93 E;  3S1M E;  3S14 F;  2O5J E;  5C44 F;  5IYC E;  2WAQ H;  3HOZ F;  2NVQ E;  3PO3 F;  4OIO E;  1WCM E;  4A3E E;  5D4E E;  5M5X F;  2E2H F;  4BXX F;  2NVT E;  5FLM E;  4KMU E;  4G7Z E;  2NVX F;  5FJ8 E;  3S15 E;  4C3I F;  4YFK E;  1YNJ K;  5D4D E;  2NVY F;  4Q4Z E;  4AYB K;  4QIW H;  5M5W F;  2YU9 E;  3S1N F;  5E17 E;  2WB1 I;  5C3E E;  1I50 E;  4C2M E;  4A3F E;  4XSX E;  5M3F F;  2PMZ K;  1YNN K;  2KRX A;  1I3Q F;  2WB1 H;  1SFO F;  4LLG E;  2A6H E;  4Q5S E;  5IYD F;  3GTP E;  1ZYR E;  4X6A E;  3GTJ F;  4A3J E;  3GTQ E;  3S2D E;  3CQZ F;  3FKI F;  4A3K F;  3GTK E;  1TWH E;  5IP9 F;  3S17 E;  2CW0 E;  4BY7 E;  1I6H F;  2JA7 F;  1I6V E;  5IYB E;  3GTG E;  5M3M F;  2JA8 F;  4A3C E;  1TWF F;  1R9T F;  5IPL E;  2PMZ H;  2R7Z F;  2E2J F;  2E2I E;  2JA6 E;  4BBS F;  2O5I E;  3HOU E;  5C4J E;  1K83 F;  3GTL F;  3S2H E;  3I4M F;  3GTO E;  4MEY E;  3S1R F;  3I4N E;  1HQM E;  3S1M F;  4A93 F;  1TWG E;  3HOY E;  5M5X E;  5IYC F;  4MEX E;  3HKZ H;  5IP7 E;  1WCM F;  5BYH E;  4A3E F;  4LK0 E;  4ZH4 E;  5M5Y E;  2NVT F;  5FLM F;  4BXX E;  2Y0S I;  3M4O E;  4OIP E;  3S15 F;  3WOD E;  4Y52 E;  2YU9 F;  2Y0S H;  4BBR E;  5C44 E;  4YG2 E;  3HOV F;  2A69 E;  2B63 E;  5C3E F;  4A3F F;  4C3H E;  4A3L E;  3EQL E;  3PO3 E;  2BE5 E;  4AYB H;  4X6A F;  4XLP E;  3GTQ F;  3S2D F;  3H0G E;  1Y1W E;  3GTK F;  1DZF A;  3S17 F;  1TWC E;  3K7A E;  4BY7 F;  3H3V G;  4Y7N E;  5IYB F;  3GTG F;  4XLN E;  3RZO E;  3S1Q F;  2JA5 E;  4A3G F;  3GTM E;  4G7O E;  1SFO E;  1Y1V E;  3PO2 E;  2R93 E;  2A6E E;  4A3C F;  2VUM F;  4YFN E;  1IW7 E;  2E2I F;  2JA6 F;  4BY1 E;  3HOW E;  5C4J F;  3M3Y E;  4A3B E;  2R92 E;  4A3D E;  5TMC E;  2NVQ F;  3S16 E;  4C3J E;  3GTO F;  3S2H F;  5C4X E;  2PPB E;  3I4N F;  1TWA E;  4A3I E;  4A3M E;  1TWG F;  2WAQ K;  4OIR E;  3HOY F;  3HOX E;  5FJ8 F;  4XSZ E;  4GZY E;  5IP7 F;  5D4C E;  3S14 E;  1EIK A;  5M5Y F;  1I50 F;  3I4M E;  3HOZ E;  4C2M F;  3M4O F;  4QIW K;  4Y52 F;  3RZD F;  3H3V F;  4BBR F;  1SMY E; 
#chains in the Genus database with same CATH homology
 2NVX E;  4C3I E;  2NVY E;  3S1N E;  5M5W E;  3RZD E;  5M3F E;  1I3Q E;  5IYD E;  3HOV E;  3GTJ E;  4A3K E;  2E2H E;  3CQZ E;  3FKI E;  5IP9 E;  1I6H E;  2JA7 E;  5M3M E;  2JA8 E;  1TWF E;  1R9T E;  2R7Z E;  2E2J E;  4BBS E;  3S1Q E;  4A3G E;  1K83 E;  3GTL E;  2VUM E;  3S1R E;  4A93 E;  3S1M E;  5IYC E;  2WAQ H;  2NVQ E;  1WCM E;  4A3E E;  2NVT E;  5FLM E;  5FJ8 E;  3S15 E;  4QIW H;  2YU9 E;  5C3E E;  1I50 E;  4C2M E;  4A3F E;  2WB1 H;  3GTP E;  4X6A E;  4A3J E;  3GTQ E;  3S2D E;  3GTK E;  1TWH E;  3S17 E;  4BY7 E;  5IYB E;  3GTG E;  4A3C E;  2PMZ H;  2E2I E;  2JA6 E;  3HOU E;  5C4J E;  3S2H E;  3GTO E;  3I4N E;  1TWG E;  3HOY E;  5M5X E;  3HKZ H;  5IP7 E;  5M5Y E;  4BXX E;  3M4O E;  4Y52 E;  2Y0S H;  4BBR E;  5C44 E;  2B63 E;  4C3H E;  4A3L E;  3PO3 E;  4AYB H;  3H0G E;  1Y1W E;  1DZF A;  1TWC E;  3K7A E;  4Y7N E;  3RZO E;  2JA5 E;  3GTM E;  1SFO E;  1Y1V E;  3PO2 E;  2R93 E;  4BY1 E;  3HOW E;  3M3Y E;  4A3B E;  2R92 E;  4A3D E;  3S16 E;  4C3J E;  5C4X E;  1TWA E;  4A3I E;  4A3M E;  3HOX E;  3S14 E;  1EIK A;  3I4M E;  3HOZ E;  3H3V F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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