4A3IE

Rna polymerase ii binary complex with dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 60
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4a3iE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4a3iE02
4BBSE 4A3GE 3S2DE 1DZFA 4A3JE 3I4ME 1K83E 5M3FE 2WAQH 4Y7NE 3S1QE 4A3EE 4A3ME 2VUME 4A3KE 3HOVE 3H0GE 4C3IE 3S17E 3S15E 2R92E 5IYBE 3RZOE 3GTLE 2JA5E 5M5YE 2E2JE 2E2HE 4A3FE 3GTGE 3GTPE 1TWCE 1TWFE 4BY1E 2R93E 4X6AE 5C44E 1EIKA 2NVYE 3FKIE 4A93E 3HOWE 3S2HE 5IP7E 3S1ME 2JA6E 3GTOE 5FJ8E 1TWGE 1I3QE 5IP9E 4A3LE 3M3YE 3PO2E 2PMZH 3S14E 4BXXE 2E2IE 4A3BE 3M4OE 2B63E 3GTJE 3HOYE 3GTQE 5M5WE 5FLME 1Y1VE 1TWAE 1I6HE 5IYDE 5M3ME 4A3DE 2NVQE 1Y1WE 4BBRE 4A3IE 2YU9E 4C2ME 3S1NE 3HOXE 1I50E 2NVTE 3HKZH 4BY7E 1WCME 4Y52E 1SFOE 2NVXE 4A3CE 4AYBH 4C3HE 2Y0SH 3I4NE 3S1RE 3HOUE 3HOZE 3H3VF 2JA8E 3GTME 1TWHE 2R7ZE 5C4XE 2JA7E 4C3JE 2WB1H 5C3EE 1R9TE 3RZDE 3K7AE 3PO3E 5M5XE 5IYCE 3GTKE 3S16E 4QIWH 5C4JE 3CQZE
chains in the Genus database with same CATH superfamily
5M5YF 4BBSE 4A3GE 5TMFE 3S16F 4ZH4E 3S2DE 5C4JF 1DZFA 4A3JE 1QKLA 4LK0E 3I4ME 1YNNK 1ZYRE 1K83E 3CQZF 4OINE 2NVYF 5TMCE 4BBSF 4A3GF 5M3FE 2WAQH 4Y7NE 3S2DF 3S1QE 4Q4ZE 4A3JF 4OIOE 4A3EE 3I4MF 4A3ME 4Q5SE 3H3VG 1K83F 2VUME 4A3KE 3HOVE 3H0GE 4C3IE 3S17E 3S15E 2R92E 5IYBE 5M3FF 3RZOE 3GTLE 3WODE 3S1QF 5E17E 4OIRE 4A3EF 2JA5E 5M5YE 2E2JE 4A3MF 2E2HE 4A3FE 3GTGE 2VUMF 4A3KF 2CW0E 3GTPE 3H0GF 4C3IF 1TWCE 1TWFE 4BY1E 2R93E 4YFKE 5IYBF 4X6AE 3S15F 3RZOF 3GTLF 5C44E 3DXJE 4LK1E 4MQ9E 4G7HE 1EIKA 2NVYE 3FKIE 2JA5F 2A69E 2E2JF 4A93E 2E2HF 3HOWE 4A3FF 2PMZK 3GTGF 3GTPF 1TWCF 1TWFF 4BY1F 3S2HE 2R93F 4X6AF 3S17F 5C44F 4XSZE 3EQLE 5IP7E 3S1ME 2A68E 3FKIF 2JA6E 3GTOE 3HOWF 4A93F 2A6EE 5FJ8E 3S2HF 4GZYE 4XLNE 1TWGE 5IP7F 3S1MF 1I3QE 2A6HE 4KN7E 2JA6F 3GTOF 5IP9E 4A3LE 5FJ8F 3M3YE 3PO2E 2PMZH 3S14E 4BXXE 1TWGF 2E2IE 1I3QF 4A3BE 2BE5E 3M4OE 2B63E 4BY7F 5IP9F 3GTJE 3HOYE 4A3LF 3M3YF 3GTQE 1YNJK 5M5WE 3PO2F 5FLME 3S14F 3HKZK 1Y1VE 1TWAE 2Y0SI 5IPLE 4BXXF 1I6HE 2E2IF 3I4NF 4KN4E 5IYDE 5M3ME 4A3DE 4JK1E 2NVQE 4YFXE 4AYBK 2B63F 3GTJF 3M4OF 3HOYF 1Y1WE 3GTQF 5M5WF 4OIQE 5FLMF 4BBRE 1Y1VF 1TWAF 4A3IE 4LJZE 1I6VE 1I6HF 2YU9E 4C2ME 5M3MF 5IYDF 4A3DF 2NVQF 3S1NE 3HOXE 1Y1WF 1HQME 1I50E 2WB1I 4BBRF 2PPBE 4A3IF 2NVTE 3HKZH 4BY7E 1WCME 2YU9F 4OIPE 4Y52E 4XSXE 4C2MF 1SFOE 2NVXE 4A3CE 4AYBH 4C3HE 2Y0SH 4A3BF 3S1NF 4MEYE 3HOXF 1I50F 3GTKF 3I4NE 3S1RE 4YFNE 3HOUE 3HOZE 4G7ZE 4MEXE 2NVTF 1WCMF 4Y52F 1SFOF 2NVXF 3H3VF 4A3CF 4C3HF 2JA8E 4QIWK 4YG2E 3S1RF 3GTME 3HOUF 1TWHE 2R7ZE 5C4XE 3HOZF 2JA7E 5D4EE 4C3JE 2WB1H 4XLPE 4LLGE 5C3EE 5BYHE 2JA8F 1R9TE 2O5IE 5D4CE 3RZDE 2KRXA 3GTMF 1TWHF 3K7AE 2R7ZF 5C4XF 3PO3E 4Y7NF 2JA7F 4KMUE 4G7OE 4C3JF 5M5XE 5D4DE 5IYCE 3GTKE 1SMYE 3S16E 2WAQK 5C3EF 1R9TF 3HOVF 2O5JE 4QIWH 5C4JE 2R92F 3RZDF 3K7AF 1IW7E 3PO3F 5E18E 3CQZE 5M5XF 5IYCF
chains in the Genus database with same CATH topology
4BBSE 4A3GE 3S2DE 1DZFA 4A3JE 3I4ME 1K83E 5M3FE 2WAQH 4Y7NE 3S1QE 4A3EE 4A3ME 2VUME 4A3KE 3HOVE 3H0GE 4C3IE 3S17E 3S15E 2R92E 5IYBE 3RZOE 3GTLE 2JA5E 5M5YE 2E2JE 2E2HE 4A3FE 3GTGE 3GTPE 1TWCE 1TWFE 4BY1E 2R93E 4X6AE 5C44E 1EIKA 2NVYE 3FKIE 4A93E 3HOWE 3S2HE 5IP7E 3S1ME 2JA6E 3GTOE 5FJ8E 1TWGE 1I3QE 5IP9E 4A3LE 3M3YE 3PO2E 2PMZH 3S14E 4BXXE 2E2IE 4A3BE 3M4OE 2B63E 3GTJE 3HOYE 3GTQE 5M5WE 5FLME 1Y1VE 1TWAE 1I6HE 5IYDE 5M3ME 4A3DE 2NVQE 1Y1WE 4BBRE 4A3IE 2YU9E 4C2ME 3S1NE 3HOXE 1I50E 2NVTE 3HKZH 4BY7E 1WCME 4Y52E 1SFOE 2NVXE 4A3CE 4AYBH 4C3HE 2Y0SH 3I4NE 3S1RE 3HOUE 3HOZE 3H3VF 2JA8E 3GTME 1TWHE 2R7ZE 5C4XE 2JA7E 4C3JE 2WB1H 5C3EE 1R9TE 3RZDE 3K7AE 3PO3E 5M5XE 5IYCE 3GTKE 3S16E 4QIWH 5C4JE 3CQZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBS E;  4A3G E;  3S2D E;  1DZF A;  4A3J E;  3I4M E;  1K83 E;  5M3F E;  2WAQ H;  4Y7N E;  3S1Q E;  4A3E E;  4A3M E;  2VUM E;  4A3K E;  3HOV E;  3H0G E;  4C3I E;  3S17 E;  3S15 E;  2R92 E;  5IYB E;  3RZO E;  3GTL E;  2JA5 E;  5M5Y E;  2E2J E;  2E2H E;  4A3F E;  3GTG E;  3GTP E;  1TWC E;  1TWF E;  4BY1 E;  2R93 E;  4X6A E;  5C44 E;  1EIK A;  2NVY E;  3FKI E;  4A93 E;  3HOW E;  3S2H E;  5IP7 E;  3S1M E;  2JA6 E;  3GTO E;  5FJ8 E;  1TWG E;  1I3Q E;  5IP9 E;  4A3L E;  3M3Y E;  3PO2 E;  2PMZ H;  3S14 E;  4BXX E;  2E2I E;  4A3B E;  3M4O E;  2B63 E;  3GTJ E;  3HOY E;  3GTQ E;  5M5W E;  5FLM E;  1Y1V E;  1TWA E;  1I6H E;  5IYD E;  5M3M E;  4A3D E;  2NVQ E;  1Y1W E;  4BBR E;  4A3I E;  2YU9 E;  4C2M E;  3S1N E;  3HOX E;  1I50 E;  2NVT E;  3HKZ H;  4BY7 E;  1WCM E;  4Y52 E;  1SFO E;  2NVX E;  4A3C E;  4AYB H;  4C3H E;  2Y0S H;  3I4N E;  3S1R E;  3HOU E;  3HOZ E;  3H3V F;  2JA8 E;  3GTM E;  1TWH E;  2R7Z E;  5C4X E;  2JA7 E;  4C3J E;  2WB1 H;  5C3E E;  1R9T E;  3RZD E;  3K7A E;  3PO3 E;  5M5X E;  5IYC E;  3GTK E;  3S16 E;  4QIW H;  5C4J E;  3CQZ E; 
#chains in the Genus database with same CATH topology
 5M5Y F;  4BBS E;  4A3G E;  5TMF E;  3S16 F;  4ZH4 E;  3S2D E;  5C4J F;  1DZF A;  4A3J E;  1QKL A;  4LK0 E;  3I4M E;  1YNN K;  1ZYR E;  1K83 E;  3CQZ F;  4OIN E;  2NVY F;  5TMC E;  4BBS F;  4A3G F;  5M3F E;  2WAQ H;  4Y7N E;  3S2D F;  3S1Q E;  4Q4Z E;  4A3J F;  4OIO E;  4A3E E;  3I4M F;  4A3M E;  4Q5S E;  3H3V G;  1K83 F;  2VUM E;  4A3K E;  3HOV E;  3H0G E;  4C3I E;  3S17 E;  3S15 E;  2R92 E;  5IYB E;  5M3F F;  3RZO E;  3GTL E;  3WOD E;  3S1Q F;  5E17 E;  4OIR E;  4A3E F;  2JA5 E;  5M5Y E;  2E2J E;  4A3M F;  2E2H E;  4A3F E;  3GTG E;  2VUM F;  4A3K F;  2CW0 E;  3GTP E;  3H0G F;  4C3I F;  1TWC E;  1TWF E;  4BY1 E;  2R93 E;  4YFK E;  5IYB F;  4X6A E;  3S15 F;  3RZO F;  3GTL F;  5C44 E;  3DXJ E;  4LK1 E;  4MQ9 E;  4G7H E;  1EIK A;  2NVY E;  3FKI E;  2JA5 F;  2A69 E;  2E2J F;  4A93 E;  2E2H F;  3HOW E;  4A3F F;  2PMZ K;  3GTG F;  3GTP F;  1TWC F;  1TWF F;  4BY1 F;  3S2H E;  2R93 F;  4X6A F;  3S17 F;  5C44 F;  4XSZ E;  3EQL E;  5IP7 E;  3S1M E;  2A68 E;  3FKI F;  2JA6 E;  3GTO E;  3HOW F;  4A93 F;  2A6E E;  5FJ8 E;  3S2H F;  4GZY E;  4XLN E;  1TWG E;  5IP7 F;  3S1M F;  1I3Q E;  2A6H E;  4KN7 E;  2JA6 F;  3GTO F;  5IP9 E;  4A3L E;  5FJ8 F;  3M3Y E;  3PO2 E;  2PMZ H;  3S14 E;  4BXX E;  1TWG F;  2E2I E;  1I3Q F;  4A3B E;  2BE5 E;  3M4O E;  2B63 E;  4BY7 F;  5IP9 F;  3GTJ E;  3HOY E;  4A3L F;  3M3Y F;  3GTQ E;  1YNJ K;  5M5W E;  3PO2 F;  5FLM E;  3S14 F;  3HKZ K;  1Y1V E;  1TWA E;  2Y0S I;  5IPL E;  4BXX F;  1I6H E;  2E2I F;  3I4N F;  4KN4 E;  5IYD E;  5M3M E;  4A3D E;  4JK1 E;  2NVQ E;  4YFX E;  4AYB K;  2B63 F;  3GTJ F;  3M4O F;  3HOY F;  1Y1W E;  3GTQ F;  5M5W F;  4OIQ E;  5FLM F;  4BBR E;  1Y1V F;  1TWA F;  4A3I E;  4LJZ E;  1I6V E;  1I6H F;  2YU9 E;  4C2M E;  5M3M F;  5IYD F;  4A3D F;  2NVQ F;  3S1N E;  3HOX E;  1Y1W F;  1HQM E;  1I50 E;  2WB1 I;  4BBR F;  2PPB E;  4A3I F;  2NVT E;  3HKZ H;  4BY7 E;  1WCM E;  2YU9 F;  4OIP E;  4Y52 E;  4XSX E;  4C2M F;  1SFO E;  2NVX E;  4A3C E;  4AYB H;  4C3H E;  2Y0S H;  4A3B F;  3S1N F;  4MEY E;  3HOX F;  1I50 F;  3GTK F;  3I4N E;  3S1R E;  4YFN E;  3HOU E;  3HOZ E;  4G7Z E;  4MEX E;  2NVT F;  1WCM F;  4Y52 F;  1SFO F;  2NVX F;  3H3V F;  4A3C F;  4C3H F;  2JA8 E;  4QIW K;  4YG2 E;  3S1R F;  3GTM E;  3HOU F;  1TWH E;  2R7Z E;  5C4X E;  3HOZ F;  2JA7 E;  5D4E E;  4C3J E;  2WB1 H;  4XLP E;  4LLG E;  5C3E E;  5BYH E;  2JA8 F;  1R9T E;  2O5I E;  5D4C E;  3RZD E;  2KRX A;  3GTM F;  1TWH F;  3K7A E;  2R7Z F;  5C4X F;  3PO3 E;  4Y7N F;  2JA7 F;  4KMU E;  4G7O E;  4C3J F;  5M5X E;  5D4D E;  5IYC E;  3GTK E;  1SMY E;  3S16 E;  2WAQ K;  5C3E F;  1R9T F;  3HOV F;  2O5J E;  4QIW H;  5C4J E;  2R92 F;  3RZD F;  3K7A F;  1IW7 E;  3PO3 F;  5E18 E;  3CQZ E;  5M5X F;  5IYC F; 
#chains in the Genus database with same CATH homology
 4BBS E;  4A3G E;  3S2D E;  1DZF A;  4A3J E;  3I4M E;  1K83 E;  5M3F E;  2WAQ H;  4Y7N E;  3S1Q E;  4A3E E;  4A3M E;  2VUM E;  4A3K E;  3HOV E;  3H0G E;  4C3I E;  3S17 E;  3S15 E;  2R92 E;  5IYB E;  3RZO E;  3GTL E;  2JA5 E;  5M5Y E;  2E2J E;  2E2H E;  4A3F E;  3GTG E;  3GTP E;  1TWC E;  1TWF E;  4BY1 E;  2R93 E;  4X6A E;  5C44 E;  1EIK A;  2NVY E;  3FKI E;  4A93 E;  3HOW E;  3S2H E;  5IP7 E;  3S1M E;  2JA6 E;  3GTO E;  5FJ8 E;  1TWG E;  1I3Q E;  5IP9 E;  4A3L E;  3M3Y E;  3PO2 E;  2PMZ H;  3S14 E;  4BXX E;  2E2I E;  4A3B E;  3M4O E;  2B63 E;  3GTJ E;  3HOY E;  3GTQ E;  5M5W E;  5FLM E;  1Y1V E;  1TWA E;  1I6H E;  5IYD E;  5M3M E;  4A3D E;  2NVQ E;  1Y1W E;  4BBR E;  4A3I E;  2YU9 E;  4C2M E;  3S1N E;  3HOX E;  1I50 E;  2NVT E;  3HKZ H;  4BY7 E;  1WCM E;  4Y52 E;  1SFO E;  2NVX E;  4A3C E;  4AYB H;  4C3H E;  2Y0S H;  3I4N E;  3S1R E;  3HOU E;  3HOZ E;  3H3V F;  2JA8 E;  3GTM E;  1TWH E;  2R7Z E;  5C4X E;  2JA7 E;  4C3J E;  2WB1 H;  5C3E E;  1R9T E;  3RZD E;  3K7A E;  3PO3 E;  5M5X E;  5IYC E;  3GTK E;  3S16 E;  4QIW H;  5C4J E;  3CQZ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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