4AIPA

The frpb iron transporter from neisseria meningitidis (f3-3 variant)
Total Genus 195
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
195
sequence length
682
structure length
661
Chain Sequence
DRQGSKIRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNNGVSYGASVFGKEGNFDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDDDHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKERYSADDSGTGYAGNVKGPNHTRITTRGANFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFSIPTPMEQQMKDRADEDTVHAYKLSNPTKTDTGVYIEAIHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHNYASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQAVREAVNAGYIKNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKATGSILAAGQKNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNKFYYPHSQRWTNTLPGVGRDVRLGVNYKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Use of a Molecular Decoy to Segregate Transport from Antigenicity in the Frpb Iron Transporter from Neisseria Meningitidis
pubmed doi rcsb
molecule tags Transport protein
source organism Neisseria meningitidis
molecule keywords FE-REGULATED PROTEIN B
total genus 195
structure length 661
sequence length 682
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 4aipA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 4aipA01
2FCPA 2O5PA 2W76A 1NQHA 1NQGA 2HDFA 2YSUA 3DDRA 2IAHA 4RDTA 2GRXA 2HDIA 4EPAA 1QKCA 1BY5A 1XKWA 3CSLA 4CU4A 1QJQA 3V89A 2GUFA 4B7OA 1KMPA 1UJWA 3V8XA 1PO0A 2W6UA 2W16A 1PNZA 3QLBA 1NQEA 1NQFA 3M8DA 3CSNA 4RDRA 2W75A 1KMOA 3M8BA 1PO3A 1FI1A 1FEPA 5FOKA 2GSKA 3RGMA 1XKHA 2W6TA 2W78A 1QFFA 4AIQA 1FCPA 1BY3A 3EFMA 3FHHA 4AIPA 2W77A 1QFGA 3RGNA
chains in the Genus database with same CATH superfamily
2FCPA 1MPOA 2O5PA 2W76A 1NQHA 1NQGA 1OH2P 2HDFA 1MPQA 2YSUA 3DDRA 2IAHA 1MPRA 4RDTA 3RGNA 2GRXA 2HDIA 4EPAA 1QKCA 1BY5A 1XKWA 2MPRA 3CSLA 4CU4A 1QJQA 3V89A 2GUFA 4B7OA 1KMPA 1UJWA 3V8XA 1AF6A 2W6UA 1PO0A 2W16A 1A0TP 1MALA 3QLBA 1PNZA 1NQEA 1NQFA 1OH2Q 3M8DA 1A0SP 3CSNA 4RDRA 2W75A 1JBIA 1KMOA 3M8BA 1PO3A 1FI1A 1FEPA 5FOKA 2GSKA 3RGMA 1XKHA 2W6TA 2W78A 1QFFA 4AIQA 1FCPA 1BY3A 3EFMA 3FHHA 4AIPA 2W77A 1QFGA 1MPMA 1MPNA
chains in the Genus database with same CATH topology
2FCPA 2O5PA 2W76A 1NQHA 1NQGA 2HDFA 2YSUA 3DDRA 2IAHA 4RDTA 2GRXA 2HDIA 4EPAA 1QKCA 1BY5A 1XKWA 3CSLA 4CU4A 1QJQA 3V89A 2GUFA 4B7OA 1KMPA 1UJWA 3V8XA 1PO0A 2W6UA 2W16A 1PNZA 3QLBA 1NQEA 1NQFA 3M8DA 3CSNA 4RDRA 2W75A 1KMOA 3M8BA 1PO3A 1FI1A 1FEPA 5FOKA 2GSKA 3RGMA 1XKHA 2W6TA 2W78A 1QFFA 4AIQA 1FCPA 1BY3A 3EFMA 3FHHA 4AIPA 2W77A 1QFGA 3RGNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FCP A;  2O5P A;  2W76 A;  1NQH A;  1NQG A;  2HDF A;  2YSU A;  3DDR A;  2IAH A;  4RDT A;  2GRX A;  2HDI A;  4EPA A;  1QKC A;  1BY5 A;  1XKW A;  3CSL A;  4CU4 A;  1QJQ A;  3V89 A;  2GUF A;  4B7O A;  1KMP A;  1UJW A;  3V8X A;  1PO0 A;  2W6U A;  2W16 A;  1PNZ A;  3QLB A;  1NQE A;  1NQF A;  3M8D A;  3CSN A;  4RDR A;  2W75 A;  1KMO A;  3M8B A;  1PO3 A;  1FI1 A;  1FEP A;  5FOK A;  2GSK A;  3RGM A;  1XKH A;  2W6T A;  2W78 A;  1QFF A;  4AIQ A;  1FCP A;  1BY3 A;  3EFM A;  3FHH A;  4AIP A;  2W77 A;  1QFG A;  3RGN A; 
#chains in the Genus database with same CATH topology
 2FCP A;  1MPO A;  2O5P A;  2W76 A;  1NQH A;  1NQG A;  1OH2 P;  2HDF A;  1MPQ A;  2YSU A;  3DDR A;  2IAH A;  1MPR A;  4RDT A;  3RGN A;  2GRX A;  2HDI A;  4EPA A;  1QKC A;  1BY5 A;  1XKW A;  2MPR A;  3CSL A;  4CU4 A;  1QJQ A;  3V89 A;  2GUF A;  4B7O A;  1KMP A;  1UJW A;  3V8X A;  1AF6 A;  2W6U A;  1PO0 A;  2W16 A;  1A0T P;  1MAL A;  3QLB A;  1PNZ A;  1NQE A;  1NQF A;  1OH2 Q;  3M8D A;  1A0S P;  3CSN A;  4RDR A;  2W75 A;  1JBI A;  1KMO A;  3M8B A;  1PO3 A;  1FI1 A;  1FEP A;  5FOK A;  2GSK A;  3RGM A;  1XKH A;  2W6T A;  2W78 A;  1QFF A;  4AIQ A;  1FCP A;  1BY3 A;  3EFM A;  3FHH A;  4AIP A;  2W77 A;  1QFG A;  1MPM A;  1MPN A; 
#chains in the Genus database with same CATH homology
 2FCP A;  2O5P A;  2W76 A;  1NQH A;  1NQG A;  2HDF A;  2YSU A;  3DDR A;  2IAH A;  4RDT A;  2GRX A;  2HDI A;  4EPA A;  1QKC A;  1BY5 A;  1XKW A;  3CSL A;  4CU4 A;  1QJQ A;  3V89 A;  2GUF A;  4B7O A;  1KMP A;  1UJW A;  3V8X A;  1PO0 A;  2W6U A;  2W16 A;  1PNZ A;  3QLB A;  1NQE A;  1NQF A;  3M8D A;  3CSN A;  4RDR A;  2W75 A;  1KMO A;  3M8B A;  1PO3 A;  1FI1 A;  1FEP A;  5FOK A;  2GSK A;  3RGM A;  1XKH A;  2W6T A;  2W78 A;  1QFF A;  4AIQ A;  1FCP A;  1BY3 A;  3EFM A;  3FHH A;  4AIP A;  2W77 A;  1QFG A;  3RGN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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