4C2MF

Structure of rna polymerase i at 2.8 a resolution
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
100
structure length
100
Chain Sequence
PEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title RNA Polymerase I Structure and Transcription Regulation.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4
total genus 35
structure length 100
sequence length 100
chains with identical sequence U
ec nomenclature
pdb deposition date 2013-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4c2mF00
3HOVF 3RZOF 4XSXE 3M4OF 4OIOE 3I4NF 1TWGF 2A68E 2A6EE 2PMZK 5IPLE 3S2HF 4BBSF 4A3GF 1I3QF 4LK1E 5M3FF 1Y1VF 4Q4ZE 2PPBE 4BXXF 3S2DF 1I50F 3I4MF 3FKIF 4OINE 3M3YF 3GTGF 4A3CF 2JA7F 4OIPE 3S1NF 4YG2E 1TWHF 5E18E 3H3VG 2YU9F 4MEXE 3EQLE 3S1MF 3PO3F 3PO2F 3GTJF 4AYBK 4A3DF 5M5XF 4LJZE 4MQ9E 4Y7NF 2CW0E 1TWCF 4BBRF 5C4JF 3S16F 2JA5F 1TWAF 3HOZF 4LK0E 2B63F 1YNNK 2O5IE 4BY1F 3HKZK 2E2HF 4A3FF 3HOUF 4Q5SE 3H0GF 3S15F 4A3EF 3GTMF 4BY7F 5M3MF 3GTOF 4YFXE 3RZDF 2BE5E 2WB1I 4A93F 4G7HE 3S17F 4XLNE 5IP7F 2A6HE 4KMUE 2NVXF 2JA6F 1HQME 4A3LF 5M5YF 4A3BF 4C2MF 4JK1E 3HOYF 5C44F 5TMCE 1IW7E 2A69E 1I6HF 3HOWF 2E2JF 4A3KF 4OIRE 3S1QF 2WAQK 4C3JF 5D4CE 3K7AF 1QKLA 4C3HF 2R92F 3GTQF 3WODE 1WCMF 4KN4E 1SMYE 1Y1WF 1SFOF 5BYHE 1K83F 2O5JE 4X6AF 2R93F 4A3IF 4YFNE 5C4XF 5C3EF 4GZYE 3S14F 1I6VE 3HOXF 5M5WF 2NVQF 1TWFF 5D4DE 5FLMF 3GTPF 2E2IF 2VUMF 2R7ZF 4A3JF 4OIQE 4Y52F 5D4EE 2NVYF 4MEYE 2Y0SI 3S1RF 4LLGE 5FJ8F 2NVTF 3DXJE 4G7OE 5IYDF 3GTKF 4ZH4E 1R9TF 4XLPE 4XSZE 4KN7E 5E17E 4C3IF 4A3MF 2JA8F 4G7ZE 3GTLF 4YFKE 5IYCF 1YNJK 3CQZF 5IP9F 5IYBF 5TMFE 1ZYRE
chains in the Genus database with same CATH superfamily
3HOVF 3RZOF 4C3HE 4XSXE 1R9TE 4OIOE 3M4OF 2R92E 3I4NF 1TWGF 2A68E 2A6EE 2PMZK 1Y1WE 5IPLE 3S2HF 1K83E 3GTLE 4BBSF 5IYCE 2R93E 3HKZH 4A3GF 1I3QF 4LK1E 5M3FF 1Y1VF 5IP9E 4Q4ZE 2PPBE 4BXXF 3S2DF 1I50F 5IYBE 3I4MF 3S14E 3FKIF 4OINE 3HOVE 3M3YF 3GTGF 3RZOE 2JA7F 4OIPE 3S1NF 5M5WE 4A3CF 4YG2E 1TWHF 1TWFE 1TWGE 5E18E 2YU9F 5FLME 3EQLE 4MEXE 3H3VG 3GTPE 3S1MF 3PO3F 3S2HE 3S1ME 3PO2F 3GTJF 4BBSE 4AYBK 4A3DF 5M5XF 4Y52E 4A3GE 3S1RE 4LJZE 4MQ9E 4Y7NF 1Y1VE 2CW0E 1TWCF 4BBRF 5C4JF 5FJ8E 2NVTE 3S2DE 2WB1H 3S16F 2JA5F 1TWAF 3HOZF 3I4ME 3M3YE 4LK0E 4A3CE 2JA7E 2B63F 1YNNK 2O5IE 1TWHE 4C3IE 2YU9E 4BY1F 3HKZK 4A3ME 4A3FF 2E2HF 4Q5SE 3H0GF 2JA8E 5IYDE 4A3EF 2WAQH 3HOUF 3PO2E 3S15F 5M5XE 3CQZE 3GTMF 5C4JE 4BY7F 4BBRE 5M3MF 3GTOF 4YFXE 3S16E 3RZDF 2BE5E 2WB1I 2JA5E 3K7AE 3M4OE 3HOZE 4A93F 4G7HE 3S17F 2B63E 1EIKA 4XLNE 5IP7F 3I4NE 2A6HE 4KMUE 2NVXF 2JA6F 1HQME 4A3LF 5M5YF 3PO3E 4A3BF 3S15E 4C2MF 4JK1E 3HOYF 1I3QE 5M3FE 5C44F 4BY7E 4BXXE 1DZFA 3RZDE 1I50E 5TMCE 1IW7E 2A69E 3FKIE 1I6HF 3H3VF 3GTGE 3HOWF 2E2JF 3S17E 3S1NE 4A3KF 5IP7E 4OIRE 3S1QF 2WAQK 2NVXE 4A3LE 5M5YE 3GTJE 4C3JF 4A3DE 4QIWH 5D4CE 1QKLA 4C3HF 4Y7NE 2R92F 3GTQF 3WODE 1TWCE 1WCMF 4KN4E 1SMYE 1TWAE 1Y1WF 1SFOF 5BYHE 1K83F 3HOWE 2O5JE 4X6AF 2E2JE 2R93F 2Y0SH 4A3KE 4A3IF 4YFNE 4BY1E 5C4XF 2E2HE 5C3EF 4A3FE 3HOUE 3H0GE 4C3JE 4A3EE 4GZYE 5TMFE 3S14F 1I6VE 3GTQE 3HOXF 3GTME 5M5WF 2NVQF 1TWFF 5M3ME 5D4DE 3GTOE 5FLMF 3GTPF 1WCME 2E2IF 1SFOE 2VUMF 4A93E 2R7ZF 2PMZH 4X6AE 4A3JF 4OIQE 4Y52F 5D4EE 2NVYF 4MEYE 2Y0SI 4A3IE 3S1RF 4QIWK 2JA6E 5C4XE 5C3EE 4LLGE 4A3BE 5FJ8F 2NVTF 3DXJE 4C2ME 4G7OE 5IYDF 3HOYE 3GTKF 4ZH4E 3HOXE 1R9TF 5C44E 4XLPE 4XSZE 4KN7E 2NVQE 5E17E 4C3IF 2E2IE 4A3MF 2VUME 2JA8F 2R7ZE 4G7ZE 3GTLF 1I6HE 4YFKE 5IYCF 4A3JE 2NVYE 1YNJK 3CQZF 3S1QE 4AYBH 5IP9F 2KRXA 5IYBF 3K7AF 3GTKE 1ZYRE
chains in the Genus database with same CATH topology
3HOVF 3RZOF 4XSXE 3M4OF 4OIOE 3I4NF 1TWGF 2A68E 2A6EE 2PMZK 5IPLE 3S2HF 4BBSF 4A3GF 1I3QF 4LK1E 5M3FF 1Y1VF 4Q4ZE 2PPBE 4BXXF 3S2DF 1I50F 3I4MF 3FKIF 4OINE 3M3YF 3GTGF 4A3CF 2JA7F 4OIPE 3S1NF 4YG2E 1TWHF 5E18E 3H3VG 2YU9F 4MEXE 3EQLE 3S1MF 3PO3F 3PO2F 3GTJF 4AYBK 4A3DF 5M5XF 4LJZE 4MQ9E 4Y7NF 2CW0E 1TWCF 4BBRF 5C4JF 3S16F 2JA5F 1TWAF 3HOZF 4LK0E 2B63F 1YNNK 2O5IE 4BY1F 3HKZK 2E2HF 4A3FF 3HOUF 4Q5SE 3H0GF 3S15F 4A3EF 3GTMF 4BY7F 5M3MF 3GTOF 4YFXE 3RZDF 2BE5E 2WB1I 4A93F 4G7HE 3S17F 4XLNE 5IP7F 2A6HE 4KMUE 2NVXF 2JA6F 1HQME 4A3LF 5M5YF 4A3BF 4C2MF 4JK1E 3HOYF 5C44F 5TMCE 1IW7E 2A69E 1I6HF 3HOWF 2E2JF 4A3KF 4OIRE 3S1QF 2WAQK 4C3JF 5D4CE 3K7AF 1QKLA 4C3HF 2R92F 3GTQF 3WODE 1WCMF 4KN4E 1SMYE 1Y1WF 1SFOF 5BYHE 1K83F 2O5JE 4X6AF 2R93F 4A3IF 4YFNE 5C4XF 5C3EF 4GZYE 3S14F 1I6VE 3HOXF 5M5WF 2NVQF 1TWFF 5D4DE 5FLMF 3GTPF 2E2IF 2VUMF 2R7ZF 4A3JF 4OIQE 4Y52F 5D4EE 2NVYF 4MEYE 2Y0SI 3S1RF 4QIWK 4LLGE 5FJ8F 2NVTF 3DXJE 4G7OE 5IYDF 3GTKF 4ZH4E 1R9TF 4XLPE 4XSZE 4KN7E 5E17E 4C3IF 4A3MF 2JA8F 4G7ZE 3GTLF 4YFKE 5IYCF 1YNJK 3CQZF 5IP9F 2KRXA 5IYBF 5TMFE 1ZYRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOV F;  3RZO F;  4XSX E;  3M4O F;  4OIO E;  3I4N F;  1TWG F;  2A68 E;  2A6E E;  2PMZ K;  5IPL E;  3S2H F;  4BBS F;  4A3G F;  1I3Q F;  4LK1 E;  5M3F F;  1Y1V F;  4Q4Z E;  2PPB E;  4BXX F;  3S2D F;  1I50 F;  3I4M F;  3FKI F;  4OIN E;  3M3Y F;  3GTG F;  4A3C F;  2JA7 F;  4OIP E;  3S1N F;  4YG2 E;  1TWH F;  5E18 E;  3H3V G;  2YU9 F;  4MEX E;  3EQL E;  3S1M F;  3PO3 F;  3PO2 F;  3GTJ F;  4AYB K;  4A3D F;  5M5X F;  4LJZ E;  4MQ9 E;  4Y7N F;  2CW0 E;  1TWC F;  4BBR F;  5C4J F;  3S16 F;  2JA5 F;  1TWA F;  3HOZ F;  4LK0 E;  2B63 F;  1YNN K;  2O5I E;  4BY1 F;  3HKZ K;  2E2H F;  4A3F F;  3HOU F;  4Q5S E;  3H0G F;  3S15 F;  4A3E F;  3GTM F;  4BY7 F;  5M3M F;  3GTO F;  4YFX E;  3RZD F;  2BE5 E;  2WB1 I;  4A93 F;  4G7H E;  3S17 F;  4XLN E;  5IP7 F;  2A6H E;  4KMU E;  2NVX F;  2JA6 F;  1HQM E;  4A3L F;  5M5Y F;  4A3B F;  4C2M F;  4JK1 E;  3HOY F;  5C44 F;  5TMC E;  1IW7 E;  2A69 E;  1I6H F;  3HOW F;  2E2J F;  4A3K F;  4OIR E;  3S1Q F;  2WAQ K;  4C3J F;  5D4C E;  3K7A F;  1QKL A;  4C3H F;  2R92 F;  3GTQ F;  3WOD E;  1WCM F;  4KN4 E;  1SMY E;  1Y1W F;  1SFO F;  5BYH E;  1K83 F;  2O5J E;  4X6A F;  2R93 F;  4A3I F;  4YFN E;  5C4X F;  5C3E F;  4GZY E;  3S14 F;  1I6V E;  3HOX F;  5M5W F;  2NVQ F;  1TWF F;  5D4D E;  5FLM F;  3GTP F;  2E2I F;  2VUM F;  2R7Z F;  4A3J F;  4OIQ E;  4Y52 F;  5D4E E;  2NVY F;  4MEY E;  2Y0S I;  3S1R F;  4LLG E;  5FJ8 F;  2NVT F;  3DXJ E;  4G7O E;  5IYD F;  3GTK F;  4ZH4 E;  1R9T F;  4XLP E;  4XSZ E;  4KN7 E;  5E17 E;  4C3I F;  4A3M F;  2JA8 F;  4G7Z E;  3GTL F;  4YFK E;  5IYC F;  1YNJ K;  3CQZ F;  5IP9 F;  5IYB F;  5TMF E;  1ZYR E; 
#chains in the Genus database with same CATH topology
 3HOV F;  3RZO F;  4C3H E;  4XSX E;  1R9T E;  4OIO E;  3M4O F;  2R92 E;  3I4N F;  1TWG F;  2A68 E;  2A6E E;  2PMZ K;  1Y1W E;  5IPL E;  3S2H F;  1K83 E;  3GTL E;  4BBS F;  5IYC E;  2R93 E;  3HKZ H;  4A3G F;  1I3Q F;  4LK1 E;  5M3F F;  1Y1V F;  5IP9 E;  4Q4Z E;  2PPB E;  4BXX F;  3S2D F;  1I50 F;  5IYB E;  3I4M F;  3S14 E;  3FKI F;  4OIN E;  3HOV E;  3M3Y F;  3GTG F;  3RZO E;  2JA7 F;  4OIP E;  3S1N F;  5M5W E;  4A3C F;  4YG2 E;  1TWH F;  1TWF E;  1TWG E;  5E18 E;  2YU9 F;  5FLM E;  3EQL E;  4MEX E;  3H3V G;  3GTP E;  3S1M F;  3PO3 F;  3S2H E;  3S1M E;  3PO2 F;  3GTJ F;  4BBS E;  4AYB K;  4A3D F;  5M5X F;  4Y52 E;  4A3G E;  3S1R E;  4LJZ E;  4MQ9 E;  4Y7N F;  1Y1V E;  2CW0 E;  1TWC F;  4BBR F;  5C4J F;  5FJ8 E;  2NVT E;  3S2D E;  2WB1 H;  3S16 F;  2JA5 F;  1TWA F;  3HOZ F;  3I4M E;  3M3Y E;  4LK0 E;  4A3C E;  2JA7 E;  2B63 F;  1YNN K;  2O5I E;  1TWH E;  4C3I E;  2YU9 E;  4BY1 F;  3HKZ K;  4A3M E;  4A3F F;  2E2H F;  4Q5S E;  3H0G F;  2JA8 E;  5IYD E;  4A3E F;  2WAQ H;  3HOU F;  3PO2 E;  3S15 F;  5M5X E;  3CQZ E;  3GTM F;  5C4J E;  4BY7 F;  4BBR E;  5M3M F;  3GTO F;  4YFX E;  3S16 E;  3RZD F;  2BE5 E;  2WB1 I;  2JA5 E;  3K7A E;  3M4O E;  3HOZ E;  4A93 F;  4G7H E;  3S17 F;  2B63 E;  1EIK A;  4XLN E;  5IP7 F;  3I4N E;  2A6H E;  4KMU E;  2NVX F;  2JA6 F;  1HQM E;  4A3L F;  5M5Y F;  3PO3 E;  4A3B F;  3S15 E;  4C2M F;  4JK1 E;  3HOY F;  1I3Q E;  5M3F E;  5C44 F;  4BY7 E;  4BXX E;  1DZF A;  3RZD E;  1I50 E;  5TMC E;  1IW7 E;  2A69 E;  3FKI E;  1I6H F;  3H3V F;  3GTG E;  3HOW F;  2E2J F;  3S17 E;  3S1N E;  4A3K F;  5IP7 E;  4OIR E;  3S1Q F;  2WAQ K;  2NVX E;  4A3L E;  5M5Y E;  3GTJ E;  4C3J F;  4A3D E;  4QIW H;  5D4C E;  1QKL A;  4C3H F;  4Y7N E;  2R92 F;  3GTQ F;  3WOD E;  1TWC E;  1WCM F;  4KN4 E;  1SMY E;  1TWA E;  1Y1W F;  1SFO F;  5BYH E;  1K83 F;  3HOW E;  2O5J E;  4X6A F;  2E2J E;  2R93 F;  2Y0S H;  4A3K E;  4A3I F;  4YFN E;  4BY1 E;  5C4X F;  2E2H E;  5C3E F;  4A3F E;  3HOU E;  3H0G E;  4C3J E;  4A3E E;  4GZY E;  5TMF E;  3S14 F;  1I6V E;  3GTQ E;  3HOX F;  3GTM E;  5M5W F;  2NVQ F;  1TWF F;  5M3M E;  5D4D E;  3GTO E;  5FLM F;  3GTP F;  1WCM E;  2E2I F;  1SFO E;  2VUM F;  4A93 E;  2R7Z F;  2PMZ H;  4X6A E;  4A3J F;  4OIQ E;  4Y52 F;  5D4E E;  2NVY F;  4MEY E;  2Y0S I;  4A3I E;  3S1R F;  4QIW K;  2JA6 E;  5C4X E;  5C3E E;  4LLG E;  4A3B E;  5FJ8 F;  2NVT F;  3DXJ E;  4C2M E;  4G7O E;  5IYD F;  3HOY E;  3GTK F;  4ZH4 E;  3HOX E;  1R9T F;  5C44 E;  4XLP E;  4XSZ E;  4KN7 E;  2NVQ E;  5E17 E;  4C3I F;  2E2I E;  4A3M F;  2VUM E;  2JA8 F;  2R7Z E;  4G7Z E;  3GTL F;  1I6H E;  4YFK E;  5IYC F;  4A3J E;  2NVY E;  1YNJ K;  3CQZ F;  3S1Q E;  4AYB H;  5IP9 F;  2KRX A;  5IYB F;  3K7A F;  3GTK E;  1ZYR E; 
#chains in the Genus database with same CATH homology
 3HOV F;  3RZO F;  4XSX E;  3M4O F;  4OIO E;  3I4N F;  1TWG F;  2A68 E;  2A6E E;  2PMZ K;  5IPL E;  3S2H F;  4BBS F;  4A3G F;  1I3Q F;  4LK1 E;  5M3F F;  1Y1V F;  4Q4Z E;  2PPB E;  4BXX F;  3S2D F;  1I50 F;  3I4M F;  3FKI F;  4OIN E;  3M3Y F;  3GTG F;  4A3C F;  2JA7 F;  4OIP E;  3S1N F;  4YG2 E;  1TWH F;  5E18 E;  3H3V G;  2YU9 F;  4MEX E;  3EQL E;  3S1M F;  3PO3 F;  3PO2 F;  3GTJ F;  4AYB K;  4A3D F;  5M5X F;  4LJZ E;  4MQ9 E;  4Y7N F;  2CW0 E;  1TWC F;  4BBR F;  5C4J F;  3S16 F;  2JA5 F;  1TWA F;  3HOZ F;  4LK0 E;  2B63 F;  1YNN K;  2O5I E;  4BY1 F;  3HKZ K;  2E2H F;  4A3F F;  3HOU F;  4Q5S E;  3H0G F;  3S15 F;  4A3E F;  3GTM F;  4BY7 F;  5M3M F;  3GTO F;  4YFX E;  3RZD F;  2BE5 E;  2WB1 I;  4A93 F;  4G7H E;  3S17 F;  4XLN E;  5IP7 F;  2A6H E;  4KMU E;  2NVX F;  2JA6 F;  1HQM E;  4A3L F;  5M5Y F;  4A3B F;  4C2M F;  4JK1 E;  3HOY F;  5C44 F;  5TMC E;  1IW7 E;  2A69 E;  1I6H F;  3HOW F;  2E2J F;  4A3K F;  4OIR E;  3S1Q F;  2WAQ K;  4C3J F;  5D4C E;  3K7A F;  1QKL A;  4C3H F;  2R92 F;  3GTQ F;  3WOD E;  1WCM F;  4KN4 E;  1SMY E;  1Y1W F;  1SFO F;  5BYH E;  1K83 F;  2O5J E;  4X6A F;  2R93 F;  4A3I F;  4YFN E;  5C4X F;  5C3E F;  4GZY E;  3S14 F;  1I6V E;  3HOX F;  5M5W F;  2NVQ F;  1TWF F;  5D4D E;  5FLM F;  3GTP F;  2E2I F;  2VUM F;  2R7Z F;  4A3J F;  4OIQ E;  4Y52 F;  5D4E E;  2NVY F;  4MEY E;  2Y0S I;  3S1R F;  4QIW K;  4LLG E;  5FJ8 F;  2NVT F;  3DXJ E;  4G7O E;  5IYD F;  3GTK F;  4ZH4 E;  1R9T F;  4XLP E;  4XSZ E;  4KN7 E;  5E17 E;  4C3I F;  4A3M F;  2JA8 F;  4G7Z E;  3GTL F;  4YFK E;  5IYC F;  1YNJ K;  3CQZ F;  5IP9 F;  2KRX A;  5IYB F;  5TMF E;  1ZYR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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