4C3JE

Structure of 14-subunit rna polymerase i at 3.35 a resolution, crystal form c2-90
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
215
structure length
215
Chain Sequence
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
total genus 65
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 4c3jE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 4c3jE02
3S1RE 2JA8E 3GTQE 4A3CE 3S2DE 2VUME 3GTKE 2NVYE 5M5WE 3PO3E 2Y0SH 2NVXE 5IP7E 1EIKA 4QIWH 4A93E 5IYDE 5C44E 3S15E 1R9TE 1TWFE 1Y1WE 5FJ8E 3M3YE 4C2ME 1TWHE 4A3BE 5IYBE 2JA5E 1TWGE 3PO2E 4A3JE 3S1ME 3HOXE 3RZOE 2JA7E 1DZFA 5M5YE 3S14E 2WAQH 3RZDE 3FKIE 2R93E 3H3VF 5FLME 5M5XE 2E2IE 1K83E 5M3ME 5C4JE 4A3KE 4A3DE 3GTGE 1I3QE 4C3IE 3GTJE 4BY1E 3HOZE 5IYCE 4C3JE 3I4ME 1I6HE 4Y7NE 2JA6E 1SFOE 5C4XE 3HKZH 3CQZE 2B63E 1TWAE 5C3EE 3GTME 3S16E 1I50E 3HOUE 1Y1VE 2YU9E 3GTPE 4A3FE 3M4OE 4C3HE 3GTLE 3S2HE 4X6AE 4BBRE 3S1NE 2NVTE 5IP9E 4A3EE 1TWCE 2PMZH 4A3LE 5M3FE 2NVQE 4A3ME 4BY7E 4Y52E 1WCME 2E2HE 3K7AE 3HOWE 4AYBH 3HOVE 3S1QE 2WB1H 2R92E 3GTOE 3H0GE 2R7ZE 3HOYE 3I4NE 4A3IE 2E2JE 4BBSE 4A3GE 4BXXE 3S17E
chains in the Genus database with same CATH superfamily
3S1RE 2JA8E 3HKZK 3GTQE 4A3CE 3S2DE 1TWFF 4G7ZE 2VUME 3GTKE 3DXJE 2NVYE 5M5WE 2R7ZF 1TWHF 3M3YF 3PO3E 2A69E 2Y0SH 2NVXE 4A3IF 2E2JF 5D4CE 3EQLE 5IYBF 4ZH4E 5IP7E 4BBSF 4Q5SE 1EIKA 4QIWH 4BXXF 4A93E 5IYDE 3S17F 5C44E 4YFXE 3S1RF 3S15E 1TWGF 1R9TE 1TWFE 1Y1WE 3S2DF 5FJ8E 3M3YE 1I6VE 2KRXA 2VUMF 4C2ME 1TWHE 5M5WF 3GTKF 4MEXE 4A3BE 2PMZK 5M5YF 4OIRE 5IYBE 3RZDF 2JA5E 5IP7F 1YNNK 1QKLA 1SMYE 2A68E 4LJZE 4A93F 5IYDF 4XLPE 5C44F 4OIQE 1TWGE 3S15F 5M3MF 3PO2E 4A3JE 1R9TF 1Y1WF 3S1ME 3HOXE 5FJ8F 5C4JF 4AYBK 3RZOE 4A3DF 4C2MF 2JA7E 1DZFA 5M5YE 4A3BF 3S14E 2WAQH 3RZDE 3FKIE 2R93E 3I4MF 3H3VF 2JA5F 5FLME 2A6HE 5M5XE 2WB1I 1SFOF 2E2IE 1K83E 3H3VG 3CQZF 5M3ME 4OIPE 4KMUE 3PO2F 4A3JF 3GTMF 5C4JE 4A3KE 4A3DE 1HQME 3HOXF 3S1MF 4MQ9E 3RZOF 1I50F 2JA7F 3GTGE 1I3QE 4C3IE 3GTJE 4BY1E 3HOZE 1Y1VF 3S14F 5IYCE 4C3JE 3I4ME 1I6HE 1IW7E 1YNJK 3FKIF 4Y7NE 4XSZE 2JA6E 5FLMF 2R93F 5TMCE 1SFOE 5C4XE 5M5XF 3HKZH 2E2IF 3CQZE 2B63E 1TWAE 1K83F 3WODE 5C3EE 2NVTF 2CW0E 3GTME 3S16E 4LK0E 5TMFE 4OINE 4A3KF 4KN7E 1I50E 3HOUE 3GTGF 1Y1VE 1I3QF 1ZYRE 2YU9E 2BE5E 3GTPE 4LLGE 4QIWK 4BY1F 4C3IF 5IYCF 3GTJF 4A3FE 2Y0SI 4XSXE 4C3JF 4A3MF 2PPBE 3M4OE 4YFKE 4Y7NF 1I6HF 2JA6F 5IPLE 4Y52F 4C3HE 5C4XF 4JK1E 3GTLE 5E17E 3S2HE 1TWAF 4X6AE 2B63F 4BBRE 5C3EF 3S1NE 4G7HE 3HOZF 2NVTE 5IP9E 4A3EE 3S16F 4LK1E 3HOVF 4MEYE 3S1QF 1TWCE 2PMZH 4A3LE 2A6EE 5M3FE 3HOUF 4OIOE 2NVQE 2YU9F 4A3ME 3GTPF 4A3FF 4BY7E 3M4OF 4Y52E 1WCME 2O5JE 2E2HE 3H0GF 4C3HF 3GTLF 3S2HF 3HOYF 4X6AF 4BBRF 3I4NF 3S1NF 3K7AE 3HOWE 4AYBH 4YFNE 2NVQF 5IP9F 2O5IE 3HOVE 3S1QE 5BYHE 2WB1H 4A3EF 4A3GF 2R92E 1TWCF 2WAQK 4YG2E 4Q4ZE 4A3LF 4GZYE 3GTOE 5M3FF 5D4DE 4G7OE 2JA8F 5E18E 3GTQF 4BY7F 4A3CF 5D4EE 3H0GE 2R7ZE 1WCMF 2NVYF 2E2HF 3HOYE 3PO3F 3I4NE 3K7AF 4A3IE 2E2JE 2NVXF 3HOWF 4KN4E 4BBSE 4A3GE 2R92F 4XLNE 4BXXE 3S17E 3GTOF
chains in the Genus database with same CATH topology
3S1RE 2JA8E 3GTQE 4A3CE 3S2DE 2VUME 3GTKE 2NVYE 5M5WE 3PO3E 2Y0SH 2NVXE 5IP7E 1EIKA 4QIWH 4A93E 5IYDE 5C44E 3S15E 1R9TE 1TWFE 1Y1WE 5FJ8E 3M3YE 4C2ME 1TWHE 4A3BE 5IYBE 2JA5E 1TWGE 3PO2E 4A3JE 3S1ME 3HOXE 3RZOE 2JA7E 1DZFA 5M5YE 3S14E 2WAQH 3RZDE 3FKIE 2R93E 3H3VF 5FLME 5M5XE 2E2IE 1K83E 5M3ME 5C4JE 4A3KE 4A3DE 3GTGE 1I3QE 4C3IE 3GTJE 4BY1E 3HOZE 5IYCE 4C3JE 3I4ME 1I6HE 4Y7NE 2JA6E 1SFOE 5C4XE 3HKZH 3CQZE 2B63E 1TWAE 5C3EE 3GTME 3S16E 1I50E 3HOUE 1Y1VE 2YU9E 3GTPE 4A3FE 3M4OE 4C3HE 3GTLE 3S2HE 4X6AE 4BBRE 3S1NE 2NVTE 5IP9E 4A3EE 1TWCE 2PMZH 4A3LE 5M3FE 2NVQE 4A3ME 4BY7E 4Y52E 1WCME 2E2HE 3K7AE 3HOWE 4AYBH 3HOVE 3S1QE 2WB1H 2R92E 3GTOE 3H0GE 2R7ZE 3HOYE 3I4NE 4A3IE 2E2JE 4BBSE 4A3GE 4BXXE 3S17E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1R E;  2JA8 E;  3GTQ E;  4A3C E;  3S2D E;  2VUM E;  3GTK E;  2NVY E;  5M5W E;  3PO3 E;  2Y0S H;  2NVX E;  5IP7 E;  1EIK A;  4QIW H;  4A93 E;  5IYD E;  5C44 E;  3S15 E;  1R9T E;  1TWF E;  1Y1W E;  5FJ8 E;  3M3Y E;  4C2M E;  1TWH E;  4A3B E;  5IYB E;  2JA5 E;  1TWG E;  3PO2 E;  4A3J E;  3S1M E;  3HOX E;  3RZO E;  2JA7 E;  1DZF A;  5M5Y E;  3S14 E;  2WAQ H;  3RZD E;  3FKI E;  2R93 E;  3H3V F;  5FLM E;  5M5X E;  2E2I E;  1K83 E;  5M3M E;  5C4J E;  4A3K E;  4A3D E;  3GTG E;  1I3Q E;  4C3I E;  3GTJ E;  4BY1 E;  3HOZ E;  5IYC E;  4C3J E;  3I4M E;  1I6H E;  4Y7N E;  2JA6 E;  1SFO E;  5C4X E;  3HKZ H;  3CQZ E;  2B63 E;  1TWA E;  5C3E E;  3GTM E;  3S16 E;  1I50 E;  3HOU E;  1Y1V E;  2YU9 E;  3GTP E;  4A3F E;  3M4O E;  4C3H E;  3GTL E;  3S2H E;  4X6A E;  4BBR E;  3S1N E;  2NVT E;  5IP9 E;  4A3E E;  1TWC E;  2PMZ H;  4A3L E;  5M3F E;  2NVQ E;  4A3M E;  4BY7 E;  4Y52 E;  1WCM E;  2E2H E;  3K7A E;  3HOW E;  4AYB H;  3HOV E;  3S1Q E;  2WB1 H;  2R92 E;  3GTO E;  3H0G E;  2R7Z E;  3HOY E;  3I4N E;  4A3I E;  2E2J E;  4BBS E;  4A3G E;  4BXX E;  3S17 E; 
#chains in the Genus database with same CATH topology
 3S1R E;  2JA8 E;  3HKZ K;  3GTQ E;  4A3C E;  3S2D E;  1TWF F;  4G7Z E;  2VUM E;  3GTK E;  3DXJ E;  2NVY E;  5M5W E;  2R7Z F;  1TWH F;  3M3Y F;  3PO3 E;  2A69 E;  2Y0S H;  2NVX E;  4A3I F;  2E2J F;  5D4C E;  3EQL E;  5IYB F;  4ZH4 E;  5IP7 E;  4BBS F;  4Q5S E;  1EIK A;  4QIW H;  4BXX F;  4A93 E;  5IYD E;  3S17 F;  5C44 E;  4YFX E;  3S1R F;  3S15 E;  1TWG F;  1R9T E;  1TWF E;  1Y1W E;  3S2D F;  5FJ8 E;  3M3Y E;  1I6V E;  2KRX A;  2VUM F;  4C2M E;  1TWH E;  5M5W F;  3GTK F;  4MEX E;  4A3B E;  2PMZ K;  5M5Y F;  4OIR E;  5IYB E;  3RZD F;  2JA5 E;  5IP7 F;  1YNN K;  1QKL A;  1SMY E;  2A68 E;  4LJZ E;  4A93 F;  5IYD F;  4XLP E;  5C44 F;  4OIQ E;  1TWG E;  3S15 F;  5M3M F;  3PO2 E;  4A3J E;  1R9T F;  1Y1W F;  3S1M E;  3HOX E;  5FJ8 F;  5C4J F;  4AYB K;  3RZO E;  4A3D F;  4C2M F;  2JA7 E;  1DZF A;  5M5Y E;  4A3B F;  3S14 E;  2WAQ H;  3RZD E;  3FKI E;  2R93 E;  3I4M F;  3H3V F;  2JA5 F;  5FLM E;  2A6H E;  5M5X E;  2WB1 I;  1SFO F;  2E2I E;  1K83 E;  3H3V G;  3CQZ F;  5M3M E;  4OIP E;  4KMU E;  3PO2 F;  4A3J F;  3GTM F;  5C4J E;  4A3K E;  4A3D E;  1HQM E;  3HOX F;  3S1M F;  4MQ9 E;  3RZO F;  1I50 F;  2JA7 F;  3GTG E;  1I3Q E;  4C3I E;  3GTJ E;  4BY1 E;  3HOZ E;  1Y1V F;  3S14 F;  5IYC E;  4C3J E;  3I4M E;  1I6H E;  1IW7 E;  1YNJ K;  3FKI F;  4Y7N E;  4XSZ E;  2JA6 E;  5FLM F;  2R93 F;  5TMC E;  1SFO E;  5C4X E;  5M5X F;  3HKZ H;  2E2I F;  3CQZ E;  2B63 E;  1TWA E;  1K83 F;  3WOD E;  5C3E E;  2NVT F;  2CW0 E;  3GTM E;  3S16 E;  4LK0 E;  5TMF E;  4OIN E;  4A3K F;  4KN7 E;  1I50 E;  3HOU E;  3GTG F;  1Y1V E;  1I3Q F;  1ZYR E;  2YU9 E;  2BE5 E;  3GTP E;  4LLG E;  4QIW K;  4BY1 F;  4C3I F;  5IYC F;  3GTJ F;  4A3F E;  2Y0S I;  4XSX E;  4C3J F;  4A3M F;  2PPB E;  3M4O E;  4YFK E;  4Y7N F;  1I6H F;  2JA6 F;  5IPL E;  4Y52 F;  4C3H E;  5C4X F;  4JK1 E;  3GTL E;  5E17 E;  3S2H E;  1TWA F;  4X6A E;  2B63 F;  4BBR E;  5C3E F;  3S1N E;  4G7H E;  3HOZ F;  2NVT E;  5IP9 E;  4A3E E;  3S16 F;  4LK1 E;  3HOV F;  4MEY E;  3S1Q F;  1TWC E;  2PMZ H;  4A3L E;  2A6E E;  5M3F E;  3HOU F;  4OIO E;  2NVQ E;  2YU9 F;  4A3M E;  3GTP F;  4A3F F;  4BY7 E;  3M4O F;  4Y52 E;  1WCM E;  2O5J E;  2E2H E;  3H0G F;  4C3H F;  3GTL F;  3S2H F;  3HOY F;  4X6A F;  4BBR F;  3I4N F;  3S1N F;  3K7A E;  3HOW E;  4AYB H;  4YFN E;  2NVQ F;  5IP9 F;  2O5I E;  3HOV E;  3S1Q E;  5BYH E;  2WB1 H;  4A3E F;  4A3G F;  2R92 E;  1TWC F;  2WAQ K;  4YG2 E;  4Q4Z E;  4A3L F;  4GZY E;  3GTO E;  5M3F F;  5D4D E;  4G7O E;  2JA8 F;  5E18 E;  3GTQ F;  4BY7 F;  4A3C F;  5D4E E;  3H0G E;  2R7Z E;  1WCM F;  2NVY F;  2E2H F;  3HOY E;  3PO3 F;  3I4N E;  3K7A F;  4A3I E;  2E2J E;  2NVX F;  3HOW F;  4KN4 E;  4BBS E;  4A3G E;  2R92 F;  4XLN E;  4BXX E;  3S17 E;  3GTO F; 
#chains in the Genus database with same CATH homology
 3S1R E;  2JA8 E;  3GTQ E;  4A3C E;  3S2D E;  2VUM E;  3GTK E;  2NVY E;  5M5W E;  3PO3 E;  2Y0S H;  2NVX E;  5IP7 E;  1EIK A;  4QIW H;  4A93 E;  5IYD E;  5C44 E;  3S15 E;  1R9T E;  1TWF E;  1Y1W E;  5FJ8 E;  3M3Y E;  4C2M E;  1TWH E;  4A3B E;  5IYB E;  2JA5 E;  1TWG E;  3PO2 E;  4A3J E;  3S1M E;  3HOX E;  3RZO E;  2JA7 E;  1DZF A;  5M5Y E;  3S14 E;  2WAQ H;  3RZD E;  3FKI E;  2R93 E;  3H3V F;  5FLM E;  5M5X E;  2E2I E;  1K83 E;  5M3M E;  5C4J E;  4A3K E;  4A3D E;  3GTG E;  1I3Q E;  4C3I E;  3GTJ E;  4BY1 E;  3HOZ E;  5IYC E;  4C3J E;  3I4M E;  1I6H E;  4Y7N E;  2JA6 E;  1SFO E;  5C4X E;  3HKZ H;  3CQZ E;  2B63 E;  1TWA E;  5C3E E;  3GTM E;  3S16 E;  1I50 E;  3HOU E;  1Y1V E;  2YU9 E;  3GTP E;  4A3F E;  3M4O E;  4C3H E;  3GTL E;  3S2H E;  4X6A E;  4BBR E;  3S1N E;  2NVT E;  5IP9 E;  4A3E E;  1TWC E;  2PMZ H;  4A3L E;  5M3F E;  2NVQ E;  4A3M E;  4BY7 E;  4Y52 E;  1WCM E;  2E2H E;  3K7A E;  3HOW E;  4AYB H;  3HOV E;  3S1Q E;  2WB1 H;  2R92 E;  3GTO E;  3H0G E;  2R7Z E;  3HOY E;  3I4N E;  4A3I E;  2E2J E;  4BBS E;  4A3G E;  4BXX E;  3S17 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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