4FGNA

Crystal structure of the sv40 large t-antigen origin bining domain bound to site i dna
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
126
structure length
126
Chain Sequence
EDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Analysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral Assembly.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Dna binding protein/dna
source organism Simian virus 40
total genus 27
structure length 126
sequence length 126
chains with identical sequence B
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4fgnA00
4LIFA 4NBPA 1M55A 1L2MA 2IPRA 2ITJA 1Z1DB 3QN2A 2HW0A 5CYNA 2NTCA 4GDFA 5DCXA 3QK2A 4FGNA 4FB3A 5BYGA 4LMDA 1RZ9A 3QFQA 1UUTA 5D9IA 2ITLA 2FUFA 2NL8A 1L5IA 2IF9A 1TBDA 2TBDA 4ZO0A 4ZQ9A
chains in the Genus database with same CATH superfamily
4LIFA 1R9WA 4NBPA 1M55A 1L2MA 2IPRA 2ITJA 1KSYA 1Z1DB 3QN2A 4ZQ9A 2HW0A 4KW3A 1KSXA 4U87A 1F08A 5CYNA 2NTCA 4GDFA 3DKXA 5DCXA 3QK2A 4FGNA 4FB3A 5BYGA 4LMDA 1RZ9A 3QFQA 1UUTA 5D9IA 2ITLA 2FUFA 2NL8A 1L5IA 2IF9A 1TBDA 2TBDA 4ZO0A 3DKYA
chains in the Genus database with same CATH topology
4LIFA 1R9WA 4NBPA 1M55A 1L2MA 2IPRA 2ITJA 1KSYA 1Z1DB 3QN2A 4ZQ9A 2HW0A 4KW3A 1KSXA 4U87A 1F08A 5CYNA 2NTCA 4GDFA 3DKXA 5DCXA 3QK2A 4FGNA 4FB3A 5BYGA 4LMDA 1RZ9A 3QFQA 1UUTA 5D9IA 2ITLA 2FUFA 2NL8A 1L5IA 2IF9A 1TBDA 2TBDA 4ZO0A 3DKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIF A;  4NBP A;  1M55 A;  1L2M A;  2IPR A;  2ITJ A;  1Z1D B;  3QN2 A;  2HW0 A;  5CYN A;  2NTC A;  4GDF A;  5DCX A;  3QK2 A;  4FGN A;  4FB3 A;  5BYG A;  4LMD A;  1RZ9 A;  3QFQ A;  1UUT A;  5D9I A;  2ITL A;  2FUF A;  2NL8 A;  1L5I A;  2IF9 A;  1TBD A;  2TBD A;  4ZO0 A;  4ZQ9 A; 
#chains in the Genus database with same CATH topology
 4LIF A;  1R9W A;  4NBP A;  1M55 A;  1L2M A;  2IPR A;  2ITJ A;  1KSY A;  1Z1D B;  3QN2 A;  4ZQ9 A;  2HW0 A;  4KW3 A;  1KSX A;  4U87 A;  1F08 A;  5CYN A;  2NTC A;  4GDF A;  3DKX A;  5DCX A;  3QK2 A;  4FGN A;  4FB3 A;  5BYG A;  4LMD A;  1RZ9 A;  3QFQ A;  1UUT A;  5D9I A;  2ITL A;  2FUF A;  2NL8 A;  1L5I A;  2IF9 A;  1TBD A;  2TBD A;  4ZO0 A;  3DKY A; 
#chains in the Genus database with same CATH homology
 4LIF A;  1R9W A;  4NBP A;  1M55 A;  1L2M A;  2IPR A;  2ITJ A;  1KSY A;  1Z1D B;  3QN2 A;  4ZQ9 A;  2HW0 A;  4KW3 A;  1KSX A;  4U87 A;  1F08 A;  5CYN A;  2NTC A;  4GDF A;  3DKX A;  5DCX A;  3QK2 A;  4FGN A;  4FB3 A;  5BYG A;  4LMD A;  1RZ9 A;  3QFQ A;  1UUT A;  5D9I A;  2ITL A;  2FUF A;  2NL8 A;  1L5I A;  2IF9 A;  1TBD A;  2TBD A;  4ZO0 A;  3DKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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