4GSLC

Crystal structure of an atg7-atg3 crosslinked complex
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
285
structure length
186
Chain Sequence
TFLTTGQITPEEFVQAGDYLAHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPADKRAEQAIDDIDELIQDMEIKMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKLRVDQYLIVFLKFITSVTPSIQHDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
pubmed doi rcsb
molecule tags Protein transport
source organism Saccharomyces cerevisiae
molecule keywords Ubiquitin-like modifier-activating enzyme ATG7
total genus 39
structure length 186
sequence length 285
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03986 Autophagy_N Autophagocytosis associated protein (Atg3), N-terminal domain
C PF03987 Autophagy_act_C Autophagocytosis associated protein, active-site domain
C PF10381 Autophagy_C Autophagocytosis associated protein C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1460.50 Alpha Beta 2-Layer Sandwich Yope Regulator; Chain: A, Yope Regulator; Chain: A, 4gslC00
3VX8B 2DYTA 2LPUA 4GSLC 3VX7B 4EBRA
chains in the Genus database with same CATH superfamily
2P9KF 2P9IF 3DXMF 1K3SA 1TYQF 2P9SD 2MQDA 2FM8A 1K8KF 4GSLC 2P9ND 1JYOA 1L2WA 2P9LD 3CXJA 3UKRF 3DXKD 4XEIF 3TU3A 1N5BA 2BSHA 3EPUA 2P9UD 3DWLD 2P9SF 2KC5A 2LPUA 2PLGA 1U2VD 1TTWA 1XKPB 2P9LF 4G6TA 4JD2D 2BSJA 2XGAA 1XKPC 2P9NF 4JMFB 3VX7B 3VX8B 3KXYA 3ULED 3RSED 4GF3A 2BHOA 3UKUD 3DXKF 2P9PD 3DWLF 1JYAA 2P9UF 1U2VF 1K6ZA 3DXMD 4AKXA 2P9KD 2BSIA 2P9ID 1K3EA 1TYQD 4H5BA 4JD2F 2DYTA 4EBRA 3ULEF 3UKUF 1RY9A 1K8KD 2P9PF 3RSEF 1S28A 2OD0A 3UKRD 4XEID
chains in the Genus database with same CATH topology
2P9KF 2P9IF 3DXMF 1K3SA 1TYQF 2P9SD 2MQDA 2FM8A 1K8KF 4GSLC 2P9ND 1JYOA 1L2WA 2P9LD 3CXJA 3UKRF 3DXKD 4XEIF 3TU3A 1N5BA 2BSHA 2P9UD 3DWLD 2P9SF 2KC5A 2LPUA 2PLGA 1U2VD 1TTWA 1XKPB 2P9LF 4G6TA 4JD2D 2BSJA 2XGAA 1XKPC 2P9NF 4JMFB 3VX7B 3VX8B 3KXYA 3ULED 3RSED 4GF3A 2BHOA 3UKUD 3DXKF 2P9PD 3DWLF 1JYAA 2P9UF 1U2VF 1K6ZA 3DXMD 4AKXA 2P9KD 2BSIA 2P9ID 1K3EA 1TYQD 4H5BA 4JD2F 2DYTA 4EBRA 3ULEF 3UKUF 1RY9A 1K8KD 2P9PF 3RSEF 1S28A 3EPUA 3UKRD 4XEID
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VX8 B;  2DYT A;  2LPU A;  4GSL C;  3VX7 B;  4EBR A; 
#chains in the Genus database with same CATH topology
 2P9K F;  2P9I F;  3DXM F;  1K3S A;  1TYQ F;  2P9S D;  2MQD A;  2FM8 A;  1K8K F;  4GSL C;  2P9N D;  1JYO A;  1L2W A;  2P9L D;  3CXJ A;  3UKR F;  3DXK D;  4XEI F;  3TU3 A;  1N5B A;  2BSH A;  3EPU A;  2P9U D;  3DWL D;  2P9S F;  2KC5 A;  2LPU A;  2PLG A;  1U2V D;  1TTW A;  1XKP B;  2P9L F;  4G6T A;  4JD2 D;  2BSJ A;  2XGA A;  1XKP C;  2P9N F;  4JMF B;  3VX7 B;  3VX8 B;  3KXY A;  3ULE D;  3RSE D;  4GF3 A;  2BHO A;  3UKU D;  3DXK F;  2P9P D;  3DWL F;  1JYA A;  2P9U F;  1U2V F;  1K6Z A;  3DXM D;  4AKX A;  2P9K D;  2BSI A;  2P9I D;  1K3E A;  1TYQ D;  4H5B A;  4JD2 F;  2DYT A;  4EBR A;  3ULE F;  3UKU F;  1RY9 A;  1K8K D;  2P9P F;  3RSE F;  1S28 A;  2OD0 A;  3UKR D;  4XEI D; 
#chains in the Genus database with same CATH homology
 2P9K F;  2P9I F;  3DXM F;  1K3S A;  1TYQ F;  2P9S D;  2MQD A;  2FM8 A;  1K8K F;  4GSL C;  2P9N D;  1JYO A;  1L2W A;  2P9L D;  3CXJ A;  3UKR F;  3DXK D;  4XEI F;  3TU3 A;  1N5B A;  2BSH A;  2P9U D;  3DWL D;  2P9S F;  2KC5 A;  2LPU A;  2PLG A;  1U2V D;  1TTW A;  1XKP B;  2P9L F;  4G6T A;  4JD2 D;  2BSJ A;  2XGA A;  1XKP C;  2P9N F;  4JMF B;  3VX7 B;  3VX8 B;  3KXY A;  3ULE D;  3RSE D;  4GF3 A;  2BHO A;  3UKU D;  3DXK F;  2P9P D;  3DWL F;  1JYA A;  2P9U F;  1U2V F;  1K6Z A;  3DXM D;  4AKX A;  2P9K D;  2BSI A;  2P9I D;  1K3E A;  1TYQ D;  4H5B A;  4JD2 F;  2DYT A;  4EBR A;  3ULE F;  3UKU F;  1RY9 A;  1K8K D;  2P9P F;  3RSE F;  1S28 A;  3EPU A;  3UKR D;  4XEI D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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