4GSLC

Crystal structure of an atg7-atg3 crosslinked complex
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
285
structure length
186
Chain Sequence
TFLTTGQITPEEFVQAGDYLAHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPADKRAEQAIDDIDELIQDMEIKMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKLRVDQYLIVFLKFITSVTPSIQHDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
pubmed doi rcsb
molecule tags Protein transport
source organism Saccharomyces cerevisiae
molecule keywords Ubiquitin-like modifier-activating enzyme ATG7
total genus 39
structure length 186
sequence length 285
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF03986 Autophagy_N Autophagocytosis associated protein (Atg3), N-terminal domain
C PF03987 Autophagy_act_C Autophagocytosis associated protein, active-site domain
C PF10381 Autophagy_C Autophagocytosis associated protein C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1460.50 Alpha Beta 2-Layer Sandwich Yope Regulator; Chain: A, Yope Regulator; Chain: A, 4gslC00
4GSLC 2LPUA 3VX7B 2DYTA 3VX8B 4EBRA
chains in the Genus database with same CATH superfamily
4GSLC 1XKPB 1K3SA 3UKUD 2P9PF 1K3EA 1N5BA 2FM8A 4XEIF 3TU3A 3DWLF 2P9KF 2KC5A 3DXMF 4H5BA 2P9NF 3UKRD 2P9PD 1S28A 4JMFB 4XEID 3EPUA 4GF3A 2OD0A 2BSJA 1RY9A 2P9IF 2P9KD 3DXMD 3ULEF 3VX7B 1JYAA 3KXYA 2MQDA 1L2WA 2P9ND 3DWLD 2BHOA 2P9SF 2P9ID 1K8KF 2BSIA 3ULED 1XKPC 2P9LF 1U2VF 4JD2F 1TYQF 3DXKF 2DYTA 2P9UF 3VX8B 2P9SD 2BSHA 1K8KD 3RSEF 4EBRA 3CXJA 2P9LD 2PLGA 1U2VD 2LPUA 1JYOA 4JD2D 1TTWA 4G6TA 1TYQD 2XGAA 3DXKD 3UKUF 2P9UD 4AKXA 3RSED 3UKRF 1K6ZA
chains in the Genus database with same CATH topology
4GSLC 1XKPB 1K3SA 3UKUD 2P9PF 1K3EA 1N5BA 2FM8A 4XEIF 3TU3A 3DWLF 2P9KF 2KC5A 3DXMF 4H5BA 2P9NF 3UKRD 2P9PD 1S28A 4JMFB 4XEID 3EPUA 4GF3A 2BSJA 1RY9A 2P9IF 2P9KD 3DXMD 3ULEF 3VX7B 1JYAA 3KXYA 2MQDA 1L2WA 2P9ND 3DWLD 2BHOA 2P9SF 2P9ID 1K8KF 2BSIA 3ULED 1XKPC 2P9LF 1U2VF 4JD2F 1TYQF 3DXKF 2DYTA 2P9UF 3VX8B 2P9SD 2BSHA 1K8KD 3RSEF 4EBRA 3CXJA 2P9LD 2PLGA 1U2VD 2LPUA 1JYOA 4JD2D 1TTWA 4G6TA 1TYQD 2XGAA 3DXKD 3UKUF 2P9UD 4AKXA 3RSED 3UKRF 1K6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GSL C;  2LPU A;  3VX7 B;  2DYT A;  3VX8 B;  4EBR A; 
#chains in the Genus database with same CATH topology
 4GSL C;  1XKP B;  1K3S A;  3UKU D;  2P9P F;  1K3E A;  1N5B A;  2FM8 A;  4XEI F;  3TU3 A;  3DWL F;  2P9K F;  2KC5 A;  3DXM F;  4H5B A;  2P9N F;  3UKR D;  2P9P D;  1S28 A;  4JMF B;  4XEI D;  3EPU A;  4GF3 A;  2OD0 A;  2BSJ A;  1RY9 A;  2P9I F;  2P9K D;  3DXM D;  3ULE F;  3VX7 B;  1JYA A;  3KXY A;  2MQD A;  1L2W A;  2P9N D;  3DWL D;  2BHO A;  2P9S F;  2P9I D;  1K8K F;  2BSI A;  3ULE D;  1XKP C;  2P9L F;  1U2V F;  4JD2 F;  1TYQ F;  3DXK F;  2DYT A;  2P9U F;  3VX8 B;  2P9S D;  2BSH A;  1K8K D;  3RSE F;  4EBR A;  3CXJ A;  2P9L D;  2PLG A;  1U2V D;  2LPU A;  1JYO A;  4JD2 D;  1TTW A;  4G6T A;  1TYQ D;  2XGA A;  3DXK D;  3UKU F;  2P9U D;  4AKX A;  3RSE D;  3UKR F;  1K6Z A; 
#chains in the Genus database with same CATH homology
 4GSL C;  1XKP B;  1K3S A;  3UKU D;  2P9P F;  1K3E A;  1N5B A;  2FM8 A;  4XEI F;  3TU3 A;  3DWL F;  2P9K F;  2KC5 A;  3DXM F;  4H5B A;  2P9N F;  3UKR D;  2P9P D;  1S28 A;  4JMF B;  4XEI D;  3EPU A;  4GF3 A;  2BSJ A;  1RY9 A;  2P9I F;  2P9K D;  3DXM D;  3ULE F;  3VX7 B;  1JYA A;  3KXY A;  2MQD A;  1L2W A;  2P9N D;  3DWL D;  2BHO A;  2P9S F;  2P9I D;  1K8K F;  2BSI A;  3ULE D;  1XKP C;  2P9L F;  1U2V F;  4JD2 F;  1TYQ F;  3DXK F;  2DYT A;  2P9U F;  3VX8 B;  2P9S D;  2BSH A;  1K8K D;  3RSE F;  4EBR A;  3CXJ A;  2P9L D;  2PLG A;  1U2V D;  2LPU A;  1JYO A;  4JD2 D;  1TTW A;  4G6T A;  1TYQ D;  2XGA A;  3DXK D;  3UKU F;  2P9U D;  4AKX A;  3RSE D;  3UKR F;  1K6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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