4H5UA

Structural insights into yeast nit2: wild-type yeast nit2
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
303
structure length
302
Chain Sequence
LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAIYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Probable hydrolase NIT2
total genus 94
structure length 302
sequence length 303
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.128: Deaminated glutathione amidase.
pdb deposition date 2012-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 4h5uA00
2E2LA 1UF4A 2W1VA 3IVZA 2E2KA 4IZTA 4IZUA 5KHAA 2E11A 2UXYA 2DYUA 1UF7A 5JQNA 3SDBA 3SEZA 1FO6A 3IW3A 4HGDA 3DLAA 4IZSA 2GGLA 5H8LA 3KLCA 4KZFA 3HKXA 2GGKA 4IZWA 5H8IA 1J31A 2DYVA 1UF8A 3SZGA 4IZVA 2VHHA 4CYGA 4HG5A 3SYTA 4HG3A 4GYLA 3KI8A 3SEQA 4F4HA 3ILVA 1UF5A 3N05A 2VHIA 5H8JA 3P8KA 3WUYA 4CYYA 1F89A 4H5UA 4CYFA 1ERZA 2PLQA 4GYNA 1EMSA 4LF0A 5H8KA
chains in the Genus database with same CATH superfamily
2E2LA 1UF4A 2W1VA 3IVZA 2E2KA 4IZTA 4IZUA 5KHAA 2E11A 2UXYA 2DYUA 1UF7A 5JQNA 3SDBA 3SEZA 1FO6A 3IW3A 4HGDA 3DLAA 4IZSA 2GGLA 5H8LA 3KLCA 4KZFA 3HKXA 2GGKA 4IZWA 5H8IA 1J31A 2DYVA 1UF8A 3SZGA 4IZVA 2VHHA 4CYGA 4HG5A 3SYTA 4HG3A 4GYLA 3KI8A 3SEQA 4F4HA 3ILVA 1UF5A 3N05A 2VHIA 5H8JA 3P8KA 3WUYA 4CYYA 1F89A 4H5UA 4CYFA 1ERZA 2PLQA 4GYNA 1EMSA 4LF0A 5H8KA
chains in the Genus database with same CATH topology
2E2LA 1UF4A 2W1VA 3IVZA 2E2KA 4IZTA 4IZUA 5KHAA 2E11A 2UXYA 2DYUA 1UF7A 5JQNA 3SDBA 3SEZA 1FO6A 3IW3A 4HGDA 3DLAA 4IZSA 2GGLA 5H8LA 3KLCA 4KZFA 3HKXA 2GGKA 4IZWA 5H8IA 1J31A 2DYVA 1UF8A 3SZGA 4IZVA 2VHHA 4CYGA 4HG5A 3SYTA 4HG3A 4GYLA 3KI8A 3SEQA 4F4HA 3ILVA 1UF5A 3N05A 2VHIA 5H8JA 3P8KA 3WUYA 4CYYA 1F89A 4H5UA 4CYFA 1ERZA 2PLQA 4GYNA 1EMSA 4LF0A 5H8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E2L A;  1UF4 A;  2W1V A;  3IVZ A;  2E2K A;  4IZT A;  4IZU A;  5KHA A;  2E11 A;  2UXY A;  2DYU A;  1UF7 A;  5JQN A;  3SDB A;  3SEZ A;  1FO6 A;  3IW3 A;  4HGD A;  3DLA A;  4IZS A;  2GGL A;  5H8L A;  3KLC A;  4KZF A;  3HKX A;  2GGK A;  4IZW A;  5H8I A;  1J31 A;  2DYV A;  1UF8 A;  3SZG A;  4IZV A;  2VHH A;  4CYG A;  4HG5 A;  3SYT A;  4HG3 A;  4GYL A;  3KI8 A;  3SEQ A;  4F4H A;  3ILV A;  1UF5 A;  3N05 A;  2VHI A;  5H8J A;  3P8K A;  3WUY A;  4CYY A;  1F89 A;  4H5U A;  4CYF A;  1ERZ A;  2PLQ A;  4GYN A;  1EMS A;  4LF0 A;  5H8K A; 
#chains in the Genus database with same CATH topology
 2E2L A;  1UF4 A;  2W1V A;  3IVZ A;  2E2K A;  4IZT A;  4IZU A;  5KHA A;  2E11 A;  2UXY A;  2DYU A;  1UF7 A;  5JQN A;  3SDB A;  3SEZ A;  1FO6 A;  3IW3 A;  4HGD A;  3DLA A;  4IZS A;  2GGL A;  5H8L A;  3KLC A;  4KZF A;  3HKX A;  2GGK A;  4IZW A;  5H8I A;  1J31 A;  2DYV A;  1UF8 A;  3SZG A;  4IZV A;  2VHH A;  4CYG A;  4HG5 A;  3SYT A;  4HG3 A;  4GYL A;  3KI8 A;  3SEQ A;  4F4H A;  3ILV A;  1UF5 A;  3N05 A;  2VHI A;  5H8J A;  3P8K A;  3WUY A;  4CYY A;  1F89 A;  4H5U A;  4CYF A;  1ERZ A;  2PLQ A;  4GYN A;  1EMS A;  4LF0 A;  5H8K A; 
#chains in the Genus database with same CATH homology
 2E2L A;  1UF4 A;  2W1V A;  3IVZ A;  2E2K A;  4IZT A;  4IZU A;  5KHA A;  2E11 A;  2UXY A;  2DYU A;  1UF7 A;  5JQN A;  3SDB A;  3SEZ A;  1FO6 A;  3IW3 A;  4HGD A;  3DLA A;  4IZS A;  2GGL A;  5H8L A;  3KLC A;  4KZF A;  3HKX A;  2GGK A;  4IZW A;  5H8I A;  1J31 A;  2DYV A;  1UF8 A;  3SZG A;  4IZV A;  2VHH A;  4CYG A;  4HG5 A;  3SYT A;  4HG3 A;  4GYL A;  3KI8 A;  3SEQ A;  4F4H A;  3ILV A;  1UF5 A;  3N05 A;  2VHI A;  5H8J A;  3P8K A;  3WUY A;  4CYY A;  1F89 A;  4H5U A;  4CYF A;  1ERZ A;  2PLQ A;  4GYN A;  1EMS A;  4LF0 A;  5H8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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