4HG3A

Structural insights into yeast nit2: wild-type yeast nit2 in complex with alpha-ketoglutarate
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
304
structure length
304
Chain Sequence
KLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Probable hydrolase NIT2
total genus 92
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.128: Deaminated glutathione amidase.
pdb deposition date 2012-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 4hg3A00
4HG3A 4HG5A 2W1VA 1UF5A 3HKXA 2E2LA 3KI8A 5H8JA 4F4HA 2VHHA 1EMSA 2E2KA 4IZSA 5H8KA 3SZGA 2UXYA 3DLAA 1UF8A 3WUYA 4HGDA 4KZFA 4CYGA 2DYUA 3ILVA 1J31A 5H8LA 3SEZA 3IW3A 2VHIA 2DYVA 4LF0A 1ERZA 4GYLA 1UF7A 2PLQA 4GYNA 4IZUA 5KHAA 4IZTA 2E11A 3P8KA 3SYTA 3N05A 4CYYA 2GGLA 2GGKA 4CYFA 1F89A 3SDBA 3KLCA 5JQNA 4IZWA 5H8IA 3IVZA 1FO6A 3SEQA 4H5UA 1UF4A 4IZVA
chains in the Genus database with same CATH superfamily
4HG3A 4HG5A 2W1VA 1UF5A 3HKXA 2E2LA 3KI8A 5H8JA 4F4HA 2VHHA 1EMSA 2E2KA 4IZSA 5H8KA 3SZGA 2UXYA 3DLAA 1UF8A 3WUYA 4HGDA 4KZFA 4CYGA 2DYUA 3ILVA 1J31A 5H8LA 3SEZA 3IW3A 2VHIA 2DYVA 4LF0A 1ERZA 4GYLA 1UF7A 2PLQA 4GYNA 4IZUA 5KHAA 4IZTA 2E11A 3P8KA 3SYTA 3N05A 4CYYA 2GGLA 2GGKA 4CYFA 1F89A 3SDBA 3KLCA 5JQNA 4IZWA 5H8IA 3IVZA 1FO6A 3SEQA 4H5UA 1UF4A 4IZVA
chains in the Genus database with same CATH topology
4HG3A 4HG5A 2W1VA 1UF5A 3HKXA 2E2LA 3KI8A 5H8JA 4F4HA 2VHHA 1EMSA 2E2KA 4IZSA 5H8KA 3SZGA 2UXYA 3DLAA 1UF8A 3WUYA 4HGDA 4KZFA 4CYGA 2DYUA 3ILVA 1J31A 5H8LA 3SEZA 3IW3A 2VHIA 2DYVA 4LF0A 1ERZA 4GYLA 1UF7A 2PLQA 4GYNA 4IZUA 5KHAA 4IZTA 2E11A 3P8KA 3SYTA 3N05A 4CYYA 2GGLA 2GGKA 4CYFA 1F89A 3SDBA 3KLCA 5JQNA 4IZWA 5H8IA 3IVZA 1FO6A 3SEQA 4H5UA 1UF4A 4IZVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HG3 A;  4HG5 A;  2W1V A;  1UF5 A;  3HKX A;  2E2L A;  3KI8 A;  5H8J A;  4F4H A;  2VHH A;  1EMS A;  2E2K A;  4IZS A;  5H8K A;  3SZG A;  2UXY A;  3DLA A;  1UF8 A;  3WUY A;  4HGD A;  4KZF A;  4CYG A;  2DYU A;  3ILV A;  1J31 A;  5H8L A;  3SEZ A;  3IW3 A;  2VHI A;  2DYV A;  4LF0 A;  1ERZ A;  4GYL A;  1UF7 A;  2PLQ A;  4GYN A;  4IZU A;  5KHA A;  4IZT A;  2E11 A;  3P8K A;  3SYT A;  3N05 A;  4CYY A;  2GGL A;  2GGK A;  4CYF A;  1F89 A;  3SDB A;  3KLC A;  5JQN A;  4IZW A;  5H8I A;  3IVZ A;  1FO6 A;  3SEQ A;  4H5U A;  1UF4 A;  4IZV A; 
#chains in the Genus database with same CATH topology
 4HG3 A;  4HG5 A;  2W1V A;  1UF5 A;  3HKX A;  2E2L A;  3KI8 A;  5H8J A;  4F4H A;  2VHH A;  1EMS A;  2E2K A;  4IZS A;  5H8K A;  3SZG A;  2UXY A;  3DLA A;  1UF8 A;  3WUY A;  4HGD A;  4KZF A;  4CYG A;  2DYU A;  3ILV A;  1J31 A;  5H8L A;  3SEZ A;  3IW3 A;  2VHI A;  2DYV A;  4LF0 A;  1ERZ A;  4GYL A;  1UF7 A;  2PLQ A;  4GYN A;  4IZU A;  5KHA A;  4IZT A;  2E11 A;  3P8K A;  3SYT A;  3N05 A;  4CYY A;  2GGL A;  2GGK A;  4CYF A;  1F89 A;  3SDB A;  3KLC A;  5JQN A;  4IZW A;  5H8I A;  3IVZ A;  1FO6 A;  3SEQ A;  4H5U A;  1UF4 A;  4IZV A; 
#chains in the Genus database with same CATH homology
 4HG3 A;  4HG5 A;  2W1V A;  1UF5 A;  3HKX A;  2E2L A;  3KI8 A;  5H8J A;  4F4H A;  2VHH A;  1EMS A;  2E2K A;  4IZS A;  5H8K A;  3SZG A;  2UXY A;  3DLA A;  1UF8 A;  3WUY A;  4HGD A;  4KZF A;  4CYG A;  2DYU A;  3ILV A;  1J31 A;  5H8L A;  3SEZ A;  3IW3 A;  2VHI A;  2DYV A;  4LF0 A;  1ERZ A;  4GYL A;  1UF7 A;  2PLQ A;  4GYN A;  4IZU A;  5KHA A;  4IZT A;  2E11 A;  3P8K A;  3SYT A;  3N05 A;  4CYY A;  2GGL A;  2GGK A;  4CYF A;  1F89 A;  3SDB A;  3KLC A;  5JQN A;  4IZW A;  5H8I A;  3IVZ A;  1FO6 A;  3SEQ A;  4H5U A;  1UF4 A;  4IZV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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