4HG5A

Structural insights into yeast nit2: wild-type yeast nit2 in complex with oxaloacetate
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
304
structure length
304
Chain Sequence
KLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Probable hydrolase NIT2
total genus 90
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.128: Deaminated glutathione amidase.
pdb deposition date 2012-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 4hg5A00
1UF8A 1J31A 3WUYA 1UF7A 2GGLA 5H8LA 5JQNA 4IZSA 3N05A 1ERZA 3KLCA 2E2KA 5H8IA 2PLQA 3P8KA 4F4HA 4GYLA 2GGKA 4KZFA 4LF0A 1EMSA 4HGDA 4IZVA 4IZTA 5H8KA 4IZWA 1UF4A 3DLAA 4H5UA 4CYGA 2DYUA 3KI8A 3IW3A 4GYNA 4IZUA 5H8JA 1UF5A 3IVZA 3SEZA 3ILVA 2DYVA 2W1VA 4CYFA 3SZGA 4CYYA 2E11A 5KHAA 2VHIA 1F89A 1FO6A 2E2LA 4HG3A 2VHHA 4HG5A 3HKXA 3SEQA 2UXYA 3SYTA 3SDBA
chains in the Genus database with same CATH superfamily
1UF8A 1J31A 3WUYA 1UF7A 2GGLA 5H8LA 5JQNA 4IZSA 3N05A 1ERZA 3KLCA 2E2KA 5H8IA 2PLQA 3P8KA 4F4HA 4GYLA 2GGKA 4KZFA 4LF0A 1EMSA 4HGDA 4IZVA 4IZTA 5H8KA 4IZWA 1UF4A 3DLAA 4H5UA 4CYGA 2DYUA 3KI8A 3IW3A 4GYNA 4IZUA 5H8JA 1UF5A 3IVZA 3SEZA 3ILVA 2DYVA 2W1VA 4CYFA 3SZGA 4CYYA 2E11A 5KHAA 2VHIA 1F89A 1FO6A 2E2LA 4HG3A 2VHHA 4HG5A 3HKXA 3SEQA 2UXYA 3SYTA 3SDBA
chains in the Genus database with same CATH topology
1UF8A 1J31A 3WUYA 1UF7A 2GGLA 5H8LA 5JQNA 4IZSA 3N05A 1ERZA 3KLCA 2E2KA 5H8IA 2PLQA 3P8KA 4F4HA 4GYLA 2GGKA 4KZFA 4LF0A 1EMSA 4HGDA 4IZVA 4IZTA 5H8KA 4IZWA 1UF4A 3DLAA 4H5UA 4CYGA 2DYUA 3KI8A 3IW3A 4GYNA 4IZUA 5H8JA 1UF5A 3IVZA 3SEZA 3ILVA 2DYVA 2W1VA 4CYFA 3SZGA 4CYYA 2E11A 5KHAA 2VHIA 1F89A 1FO6A 2E2LA 4HG3A 2VHHA 4HG5A 3HKXA 3SEQA 2UXYA 3SYTA 3SDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UF8 A;  1J31 A;  3WUY A;  1UF7 A;  2GGL A;  5H8L A;  5JQN A;  4IZS A;  3N05 A;  1ERZ A;  3KLC A;  2E2K A;  5H8I A;  2PLQ A;  3P8K A;  4F4H A;  4GYL A;  2GGK A;  4KZF A;  4LF0 A;  1EMS A;  4HGD A;  4IZV A;  4IZT A;  5H8K A;  4IZW A;  1UF4 A;  3DLA A;  4H5U A;  4CYG A;  2DYU A;  3KI8 A;  3IW3 A;  4GYN A;  4IZU A;  5H8J A;  1UF5 A;  3IVZ A;  3SEZ A;  3ILV A;  2DYV A;  2W1V A;  4CYF A;  3SZG A;  4CYY A;  2E11 A;  5KHA A;  2VHI A;  1F89 A;  1FO6 A;  2E2L A;  4HG3 A;  2VHH A;  4HG5 A;  3HKX A;  3SEQ A;  2UXY A;  3SYT A;  3SDB A; 
#chains in the Genus database with same CATH topology
 1UF8 A;  1J31 A;  3WUY A;  1UF7 A;  2GGL A;  5H8L A;  5JQN A;  4IZS A;  3N05 A;  1ERZ A;  3KLC A;  2E2K A;  5H8I A;  2PLQ A;  3P8K A;  4F4H A;  4GYL A;  2GGK A;  4KZF A;  4LF0 A;  1EMS A;  4HGD A;  4IZV A;  4IZT A;  5H8K A;  4IZW A;  1UF4 A;  3DLA A;  4H5U A;  4CYG A;  2DYU A;  3KI8 A;  3IW3 A;  4GYN A;  4IZU A;  5H8J A;  1UF5 A;  3IVZ A;  3SEZ A;  3ILV A;  2DYV A;  2W1V A;  4CYF A;  3SZG A;  4CYY A;  2E11 A;  5KHA A;  2VHI A;  1F89 A;  1FO6 A;  2E2L A;  4HG3 A;  2VHH A;  4HG5 A;  3HKX A;  3SEQ A;  2UXY A;  3SYT A;  3SDB A; 
#chains in the Genus database with same CATH homology
 1UF8 A;  1J31 A;  3WUY A;  1UF7 A;  2GGL A;  5H8L A;  5JQN A;  4IZS A;  3N05 A;  1ERZ A;  3KLC A;  2E2K A;  5H8I A;  2PLQ A;  3P8K A;  4F4H A;  4GYL A;  2GGK A;  4KZF A;  4LF0 A;  1EMS A;  4HGD A;  4IZV A;  4IZT A;  5H8K A;  4IZW A;  1UF4 A;  3DLA A;  4H5U A;  4CYG A;  2DYU A;  3KI8 A;  3IW3 A;  4GYN A;  4IZU A;  5H8J A;  1UF5 A;  3IVZ A;  3SEZ A;  3ILV A;  2DYV A;  2W1V A;  4CYF A;  3SZG A;  4CYY A;  2E11 A;  5KHA A;  2VHI A;  1F89 A;  1FO6 A;  2E2L A;  4HG3 A;  2VHH A;  4HG5 A;  3HKX A;  3SEQ A;  2UXY A;  3SYT A;  3SDB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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