4HGDA

Structural insights into yeast nit2: c169s mutant of yeast nit2 in complex with an endogenous peptide-like ligand
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
302
structure length
299
Chain Sequence
LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNPILKESKSVQPGKAIPDIIESPLGKLGSAISYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Saccharomyces cerevisiae
publication title Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
pubmed doi rcsb
molecule keywords Probable hydrolase NIT2
total genus 97
structure length 299
sequence length 302
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.128: Deaminated glutathione amidase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 4hgdA00
5H8KA 1EMSA 3IVZA 4CYFA 5H8JA 4CYYA 1FO6A 2VHHA 3P8KA 2DYUA 2PLQA 5H8LA 3SEZA 4CYGA 3ILVA 4LF0A 4KZFA 4IZWA 3WUYA 2E2LA 1UF5A 2GGLA 3KI8A 5JQNA 2VHIA 1F89A 4HG5A 4HGDA 2W1VA 2UXYA 3KLCA 5H8IA 4H5UA 2GGKA 1UF7A 4HG3A 4IZVA 1UF8A 3HKXA 3N05A 3SDBA 2E2KA 1J31A 5KHAA 4F4HA 4IZUA 4IZSA 2DYVA 4GYNA 4IZTA 3SYTA 3SZGA 4GYLA 3SEQA 1UF4A 3DLAA 3IW3A 1ERZA 2E11A
chains in the Genus database with same CATH superfamily
5H8KA 1EMSA 3IVZA 4CYFA 5H8JA 4CYYA 1FO6A 2VHHA 3P8KA 2DYUA 2PLQA 5H8LA 3SEZA 4CYGA 3ILVA 4LF0A 4KZFA 4IZWA 3WUYA 2E2LA 1UF5A 2GGLA 3KI8A 5JQNA 2VHIA 1F89A 4HG5A 4HGDA 2W1VA 2UXYA 3KLCA 5H8IA 4H5UA 2GGKA 1UF7A 4HG3A 4IZVA 1UF8A 3HKXA 3N05A 3SDBA 2E2KA 1J31A 5KHAA 4F4HA 4IZUA 4IZSA 2DYVA 4GYNA 4IZTA 3SYTA 3SZGA 4GYLA 3SEQA 1UF4A 3DLAA 3IW3A 1ERZA 2E11A
chains in the Genus database with same CATH topology
5H8KA 1EMSA 3IVZA 4CYFA 5H8JA 4CYYA 1FO6A 2VHHA 3P8KA 2DYUA 2PLQA 5H8LA 3SEZA 4CYGA 3ILVA 4LF0A 4KZFA 4IZWA 3WUYA 2E2LA 1UF5A 2GGLA 3KI8A 5JQNA 2VHIA 1F89A 4HG5A 4HGDA 2W1VA 2UXYA 3KLCA 5H8IA 4H5UA 2GGKA 1UF7A 4HG3A 4IZVA 1UF8A 3HKXA 3N05A 3SDBA 2E2KA 1J31A 5KHAA 4F4HA 4IZUA 4IZSA 2DYVA 4GYNA 4IZTA 3SYTA 3SZGA 4GYLA 3SEQA 1UF4A 3DLAA 3IW3A 1ERZA 2E11A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5H8K A;  1EMS A;  3IVZ A;  4CYF A;  5H8J A;  4CYY A;  1FO6 A;  2VHH A;  3P8K A;  2DYU A;  2PLQ A;  5H8L A;  3SEZ A;  4CYG A;  3ILV A;  4LF0 A;  4KZF A;  4IZW A;  3WUY A;  2E2L A;  1UF5 A;  2GGL A;  3KI8 A;  5JQN A;  2VHI A;  1F89 A;  4HG5 A;  4HGD A;  2W1V A;  2UXY A;  3KLC A;  5H8I A;  4H5U A;  2GGK A;  1UF7 A;  4HG3 A;  4IZV A;  1UF8 A;  3HKX A;  3N05 A;  3SDB A;  2E2K A;  1J31 A;  5KHA A;  4F4H A;  4IZU A;  4IZS A;  2DYV A;  4GYN A;  4IZT A;  3SYT A;  3SZG A;  4GYL A;  3SEQ A;  1UF4 A;  3DLA A;  3IW3 A;  1ERZ A;  2E11 A; 
#chains in the Genus database with same CATH topology
 5H8K A;  1EMS A;  3IVZ A;  4CYF A;  5H8J A;  4CYY A;  1FO6 A;  2VHH A;  3P8K A;  2DYU A;  2PLQ A;  5H8L A;  3SEZ A;  4CYG A;  3ILV A;  4LF0 A;  4KZF A;  4IZW A;  3WUY A;  2E2L A;  1UF5 A;  2GGL A;  3KI8 A;  5JQN A;  2VHI A;  1F89 A;  4HG5 A;  4HGD A;  2W1V A;  2UXY A;  3KLC A;  5H8I A;  4H5U A;  2GGK A;  1UF7 A;  4HG3 A;  4IZV A;  1UF8 A;  3HKX A;  3N05 A;  3SDB A;  2E2K A;  1J31 A;  5KHA A;  4F4H A;  4IZU A;  4IZS A;  2DYV A;  4GYN A;  4IZT A;  3SYT A;  3SZG A;  4GYL A;  3SEQ A;  1UF4 A;  3DLA A;  3IW3 A;  1ERZ A;  2E11 A; 
#chains in the Genus database with same CATH homology
 5H8K A;  1EMS A;  3IVZ A;  4CYF A;  5H8J A;  4CYY A;  1FO6 A;  2VHH A;  3P8K A;  2DYU A;  2PLQ A;  5H8L A;  3SEZ A;  4CYG A;  3ILV A;  4LF0 A;  4KZF A;  4IZW A;  3WUY A;  2E2L A;  1UF5 A;  2GGL A;  3KI8 A;  5JQN A;  2VHI A;  1F89 A;  4HG5 A;  4HGD A;  2W1V A;  2UXY A;  3KLC A;  5H8I A;  4H5U A;  2GGK A;  1UF7 A;  4HG3 A;  4IZV A;  1UF8 A;  3HKX A;  3N05 A;  3SDB A;  2E2K A;  1J31 A;  5KHA A;  4F4H A;  4IZU A;  4IZS A;  2DYV A;  4GYN A;  4IZT A;  3SYT A;  3SZG A;  4GYL A;  3SEQ A;  1UF4 A;  3DLA A;  3IW3 A;  1ERZ A;  2E11 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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