4HGDA

Structural insights into yeast nit2: c169s mutant of yeast nit2 in complex with an endogenous peptide-like ligand
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
302
structure length
299
Chain Sequence
LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNPILKESKSVQPGKAIPDIIESPLGKLGSAISYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Probable hydrolase NIT2
total genus 97
structure length 299
sequence length 302
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.128: Deaminated glutathione amidase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 4hgdA00
2W1VA 2GGKA 2DYVA 3SDBA 3IVZA 3SZGA 3N05A 3P8KA 4GYNA 1UF4A 3SEQA 1EMSA 4H5UA 4IZWA 3SEZA 3IW3A 5JQNA 4IZTA 5KHAA 2E11A 4IZSA 3HKXA 4KZFA 1ERZA 3ILVA 5H8IA 1J31A 4F4HA 4HG3A 4HGDA 2UXYA 4IZVA 4CYYA 1UF8A 1UF7A 3KI8A 1F89A 4CYGA 3DLAA 2GGLA 5H8KA 2DYUA 3WUYA 1UF5A 4IZUA 2E2LA 4GYLA 4CYFA 2E2KA 2VHHA 3KLCA 5H8JA 5H8LA 2VHIA 3SYTA 4LF0A 4HG5A 1FO6A 2PLQA
chains in the Genus database with same CATH superfamily
2W1VA 2GGKA 2DYVA 3SDBA 3IVZA 3SZGA 3N05A 3P8KA 4GYNA 1UF4A 3SEQA 1EMSA 4H5UA 4IZWA 3SEZA 3IW3A 5JQNA 4IZTA 5KHAA 2E11A 4IZSA 3HKXA 4KZFA 1ERZA 3ILVA 5H8IA 1J31A 4F4HA 4HG3A 4HGDA 2UXYA 4IZVA 4CYYA 1UF8A 1UF7A 3KI8A 1F89A 4CYGA 3DLAA 2GGLA 5H8KA 2DYUA 3WUYA 1UF5A 4IZUA 2E2LA 4GYLA 4CYFA 2E2KA 2VHHA 3KLCA 5H8JA 5H8LA 2VHIA 3SYTA 4LF0A 4HG5A 1FO6A 2PLQA
chains in the Genus database with same CATH topology
2W1VA 2GGKA 2DYVA 3SDBA 3IVZA 3SZGA 3N05A 3P8KA 4GYNA 1UF4A 3SEQA 1EMSA 4H5UA 4IZWA 3SEZA 3IW3A 5JQNA 4IZTA 5KHAA 2E11A 4IZSA 3HKXA 4KZFA 1ERZA 3ILVA 5H8IA 1J31A 4F4HA 4HG3A 4HGDA 2UXYA 4IZVA 4CYYA 1UF8A 1UF7A 3KI8A 1F89A 4CYGA 3DLAA 2GGLA 5H8KA 2DYUA 3WUYA 1UF5A 4IZUA 2E2LA 4GYLA 4CYFA 2E2KA 2VHHA 3KLCA 5H8JA 5H8LA 2VHIA 3SYTA 4LF0A 4HG5A 1FO6A 2PLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W1V A;  2GGK A;  2DYV A;  3SDB A;  3IVZ A;  3SZG A;  3N05 A;  3P8K A;  4GYN A;  1UF4 A;  3SEQ A;  1EMS A;  4H5U A;  4IZW A;  3SEZ A;  3IW3 A;  5JQN A;  4IZT A;  5KHA A;  2E11 A;  4IZS A;  3HKX A;  4KZF A;  1ERZ A;  3ILV A;  5H8I A;  1J31 A;  4F4H A;  4HG3 A;  4HGD A;  2UXY A;  4IZV A;  4CYY A;  1UF8 A;  1UF7 A;  3KI8 A;  1F89 A;  4CYG A;  3DLA A;  2GGL A;  5H8K A;  2DYU A;  3WUY A;  1UF5 A;  4IZU A;  2E2L A;  4GYL A;  4CYF A;  2E2K A;  2VHH A;  3KLC A;  5H8J A;  5H8L A;  2VHI A;  3SYT A;  4LF0 A;  4HG5 A;  1FO6 A;  2PLQ A; 
#chains in the Genus database with same CATH topology
 2W1V A;  2GGK A;  2DYV A;  3SDB A;  3IVZ A;  3SZG A;  3N05 A;  3P8K A;  4GYN A;  1UF4 A;  3SEQ A;  1EMS A;  4H5U A;  4IZW A;  3SEZ A;  3IW3 A;  5JQN A;  4IZT A;  5KHA A;  2E11 A;  4IZS A;  3HKX A;  4KZF A;  1ERZ A;  3ILV A;  5H8I A;  1J31 A;  4F4H A;  4HG3 A;  4HGD A;  2UXY A;  4IZV A;  4CYY A;  1UF8 A;  1UF7 A;  3KI8 A;  1F89 A;  4CYG A;  3DLA A;  2GGL A;  5H8K A;  2DYU A;  3WUY A;  1UF5 A;  4IZU A;  2E2L A;  4GYL A;  4CYF A;  2E2K A;  2VHH A;  3KLC A;  5H8J A;  5H8L A;  2VHI A;  3SYT A;  4LF0 A;  4HG5 A;  1FO6 A;  2PLQ A; 
#chains in the Genus database with same CATH homology
 2W1V A;  2GGK A;  2DYV A;  3SDB A;  3IVZ A;  3SZG A;  3N05 A;  3P8K A;  4GYN A;  1UF4 A;  3SEQ A;  1EMS A;  4H5U A;  4IZW A;  3SEZ A;  3IW3 A;  5JQN A;  4IZT A;  5KHA A;  2E11 A;  4IZS A;  3HKX A;  4KZF A;  1ERZ A;  3ILV A;  5H8I A;  1J31 A;  4F4H A;  4HG3 A;  4HGD A;  2UXY A;  4IZV A;  4CYY A;  1UF8 A;  1UF7 A;  3KI8 A;  1F89 A;  4CYG A;  3DLA A;  2GGL A;  5H8K A;  2DYU A;  3WUY A;  1UF5 A;  4IZU A;  2E2L A;  4GYL A;  4CYF A;  2E2K A;  2VHH A;  3KLC A;  5H8J A;  5H8L A;  2VHI A;  3SYT A;  4LF0 A;  4HG5 A;  1FO6 A;  2PLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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