4HI9 | Genus

Total Genus 12

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	12
sequence length	72
structure length	72
Chain Sequence	SENLYFQGSASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 72 atoms

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72 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 rcsb
molecule keywords	Integrin-linked protein kinase
molecule tags	Signaling protein
source organism	Homo sapiens
total genus	12
structure length	72
sequence length	72
ec nomenclature
pdb deposition date	2012-10-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00412	LIM	LIM domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.110.10	Mainly Beta	Ribbon	Cysteine Rich Protein	Cysteine Rich Protein	4hi9B00

1X6AA 2CUQA 2D8YA 1CXXA 2L6ZC 1NYPA 1WYHA 2IYBE 1IBIA 2CORA 1M3VA 2D8XA 1X63A 2MBVA 2D8ZA 2YPAC 1X4LA 1QLIA 2KBXB 4HI9B 1IMLA 2CO8A 1X68A 2JTNA 1A7IA 2MIUA 1CTLA 1U5SB 2LXDA 2DJ7A 1J2OA 4JCJA 1WIGA 2O13A 3IXEB 1G47A 2EGQA 1X64A 2CU8A 3F6QB 2L4ZA 2XJZA 2CURA 2CUPA 3MMKA 1X62A 1X61A 2O10A 2XJYA 1RUTX 2DFYC 1V6GA 2LZUA 4KFZA 2L6YB 4HI8B 2EHEA 1X3HA 2XQNT 2DLOA 2DARA 1B8TA
chains in the Genus database with same CATH superfamily

3NIHA 2CUQA 2L6ZC 5FXZA 1M3VA 5FXVA 1X4LA 5A1LA 2JTNA 1CTLA 5LKTA 2O13A 1G47A 4EYUA 1X64A 2XJZA 5FYMA 3ZLIA 2O10A 2DFYC 4HI8B 2EHEA 2XQNT 3ZPOA 2DARA 1NYPA 1WYHA 2MBVA 1X63A 1QLIA 2KBXB 4HI9B 3AVRA 2CO8A 5FXXA 5FXWA 1X68A 3NINA 1A7IA 1U5SB 3F6QB 4BHWA 2L4ZA 5FP3A 2CURA 4EZHA 2XJYA 5LKZA 1V6GA 4KFZA 5FY7A 2XUEA 5FY0A 2D8YA 1CXXA 3AVSA 1IBIA 2D8XA 4UF0A 4EZ4A 4ASKA 3NISA 3NIJA 2DJ7A 1J2OA 4JCJA 4UF0B 5FY1A 3IXEB 2CUPA 1X61A 3NIMA 2L6YB 2DLOA 1X6AA 2IYBE 2CORA 2D8ZA 2YPAC 1IMLA 3NILA 2MIUA 2LXDA 1WIGA 5LKUA 2EGQA 2CU8A 3MMKA 1X62A 1RUTX 5LKXA 2LZUA 3NIKA 1X3HA 1B8TA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1X6A A;  2CUQ A;  2D8Y A;  1CXX A;  2L6Z C;  1NYP A;  1WYH A;  2IYB E;  1IBI A;  2COR A;  1M3V A;  2D8X A;  1X63 A;  2MBV A;  2D8Z A;  2YPA C;  1X4L A;  1QLI A;  2KBX B;  4HI9 B;  1IML A;  2CO8 A;  1X68 A;  2JTN A;  1A7I A;  2MIU A;  1CTL A;  1U5S B;  2LXD A;  2DJ7 A;  1J2O A;  4JCJ A;  1WIG A;  2O13 A;  3IXE B;  1G47 A;  2EGQ A;  1X64 A;  2CU8 A;  3F6Q B;  2L4Z A;  2XJZ A;  2CUR A;  2CUP A;  3MMK A;  1X62 A;  1X61 A;  2O10 A;  2XJY A;  1RUT X;  2DFY C;  1V6G A;  2LZU A;  4KFZ A;  2L6Y B;  4HI8 B;  2EHE A;  1X3H A;  2XQN T;  2DLO A;  2DAR A;  1B8T A; 
#chains in the Genus database with same CATH topology
 3NIH A;  2CUQ A;  2L6Z C;  5FXZ A;  1M3V A;  5FXV A;  1X4L A;  5A1L A;  2JTN A;  1CTL A;  5LKT A;  2O13 A;  1G47 A;  4EYU A;  1X64 A;  2XJZ A;  5FYM A;  3ZLI A;  2O10 A;  2DFY C;  4HI8 B;  2EHE A;  2XQN T;  3ZPO A;  2DAR A;  1NYP A;  1WYH A;  2MBV A;  1X63 A;  1QLI A;  2KBX B;  4HI9 B;  3AVR A;  2CO8 A;  5FXX A;  5FXW A;  1X68 A;  3NIN A;  1A7I A;  1U5S B;  3F6Q B;  4BHW A;  2L4Z A;  5FP3 A;  2CUR A;  4EZH A;  2XJY A;  5LKZ A;  1V6G A;  4KFZ A;  5FY7 A;  2XUE A;  5FY0 A;  2D8Y A;  1CXX A;  3AVS A;  1IBI A;  2D8X A;  4UF0 A;  4EZ4 A;  4ASK A;  3NIS A;  3NIJ A;  2DJ7 A;  1J2O A;  4JCJ A;  4UF0 B;  5FY1 A;  3IXE B;  2CUP A;  1X61 A;  3NIM A;  2L6Y B;  2DLO A;  1X6A A;  2IYB E;  2COR A;  2D8Z A;  2YPA C;  1IML A;  3NIL A;  2MIU A;  2LXD A;  1WIG A;  5LKU A;  2EGQ A;  2CU8 A;  3MMK A;  1X62 A;  1RUT X;  5LKX A;  2LZU A;  3NIK A;  1X3H A;  1B8T A; 
#chains in the Genus database with same CATH homology
 3NIH A;  2CUQ A;  2L6Z C;  5FXZ A;  1M3V A;  5FXV A;  1X4L A;  5A1L A;  2JTN A;  1CTL A;  5LKT A;  2O13 A;  1G47 A;  4EYU A;  1X64 A;  2XJZ A;  5FYM A;  3ZLI A;  2O10 A;  2DFY C;  4HI8 B;  2EHE A;  2XQN T;  3ZPO A;  2DAR A;  1NYP A;  1WYH A;  2MBV A;  1X63 A;  1QLI A;  2KBX B;  4HI9 B;  3AVR A;  2CO8 A;  5FXX A;  5FXW A;  1X68 A;  3NIN A;  1A7I A;  1U5S B;  3F6Q B;  4BHW A;  2L4Z A;  5FP3 A;  2CUR A;  4EZH A;  2XJY A;  5LKZ A;  1V6G A;  4KFZ A;  5FY7 A;  2XUE A;  5FY0 A;  2D8Y A;  1CXX A;  3AVS A;  1IBI A;  2D8X A;  4UF0 A;  4EZ4 A;  4ASK A;  3NIS A;  3NIJ A;  2DJ7 A;  1J2O A;  4JCJ A;  4UF0 B;  5FY1 A;  3IXE B;  2CUP A;  1X61 A;  3NIM A;  2L6Y B;  2DLO A;  1X6A A;  2IYB E;  2COR A;  2D8Z A;  2YPA C;  1IML A;  3NIL A;  2MIU A;  2LXD A;  1WIG A;  5LKU A;  2EGQ A;  2CU8 A;  3MMK A;  1X62 A;  1RUT X;  5LKX A;  2LZU A;  3NIK A;  1X3H A;  1B8T A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4HI9B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations