4HKIC

Tankyrase 2 in complex with flavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hkiC00
4UI5C 4L2FC 4L34C 4UI4C 4L0TC 4UI7C 4L0SC 5ADQB 4L33C 5FPFC 4L09C 4L2GC 5C5RC 5ADTB 5C5QC 4L32C 4L0BC 4HLGC 4L0VC 4L31C 4HLHC 4HKIC 4L0IC 4HL5C 4L10C 5ADRB 4HKKB 5ADSB 4KZLC 4HMHC 4L2KC 4HLFC 4HLMC 4UI6C 4UI3C 5C5PC 4KZUC 4KZQC 4UVPB 4HKNC 4UI8C 4HLKC
chains in the Genus database with same CATH superfamily
4UI5C 4L2FC 4L34C 4UI4C 4L0TC 4UI7C 4L0SC 5ADQB 4L33C 5FPFC 4L09C 3HRYA 4L2GC 5C5RC 5ADTB 5C5QC 4L32C 4L0BC 4HLGC 4L0VC 4L31C 4HLHC 4ZLXA 2A6QA 3CTOA 3OEIE 4ZM2A 4HKIC 3HJ6A 4HL5C 4L0IC 4L10C 5ADRB 4HKKB 3K6QA 2ZIXB 5ADSB 4KZLC 4HMHC 3KH2E 4L2KC 4HLFC 4HLMC 4UI6C 4UI3C 5C5PC 3D55A 4KZUC 2ODKA 3G5OA 4KZQC 4UVPB 4HKNC 3K33B 3OEIA 3HS2A 4UI8C 4HLKC 4ZM0A
chains in the Genus database with same CATH topology
4UI5C 4L2FC 4L34C 4UI4C 4L0TC 4UI7C 4L0SC 5ADQB 4L33C 5FPFC 4L09C 4L2GC 5C5RC 5ADTB 5C5QC 4L32C 4L0BC 4HLGC 4L0VC 4L31C 4HLHC 4HKIC 4L0IC 3HJ6A 4HL5C 4L10C 5ADRB 4HKKB 5ADSB 2ZIXB 4KZLC 4HMHC 4L2KC 4HLFC 4HLMC 4UI6C 4UI3C 5C5PC 4KZUC 4KZQC 4UVPB 4HKNC 4UI8C 4HLKC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UI5 C;  4L2F C;  4L34 C;  4UI4 C;  4L0T C;  4UI7 C;  4L0S C;  5ADQ B;  4L33 C;  5FPF C;  4L09 C;  4L2G C;  5C5R C;  5ADT B;  5C5Q C;  4L32 C;  4L0B C;  4HLG C;  4L0V C;  4L31 C;  4HLH C;  4HKI C;  4L0I C;  4HL5 C;  4L10 C;  5ADR B;  4HKK B;  5ADS B;  4KZL C;  4HMH C;  4L2K C;  4HLF C;  4HLM C;  4UI6 C;  4UI3 C;  5C5P C;  4KZU C;  4KZQ C;  4UVP B;  4HKN C;  4UI8 C;  4HLK C; 
#chains in the Genus database with same CATH topology
 4UI5 C;  4L2F C;  4L34 C;  4UI4 C;  4L0T C;  4UI7 C;  4L0S C;  5ADQ B;  4L33 C;  5FPF C;  4L09 C;  3HRY A;  4L2G C;  5C5R C;  5ADT B;  5C5Q C;  4L32 C;  4L0B C;  4HLG C;  4L0V C;  4L31 C;  4HLH C;  4ZLX A;  2A6Q A;  3CTO A;  3OEI E;  4ZM2 A;  4HKI C;  3HJ6 A;  4HL5 C;  4L0I C;  4L10 C;  5ADR B;  4HKK B;  3K6Q A;  2ZIX B;  5ADS B;  4KZL C;  4HMH C;  3KH2 E;  4L2K C;  4HLF C;  4HLM C;  4UI6 C;  4UI3 C;  5C5P C;  3D55 A;  4KZU C;  2ODK A;  3G5O A;  4KZQ C;  4UVP B;  4HKN C;  3K33 B;  3OEI A;  3HS2 A;  4UI8 C;  4HLK C;  4ZM0 A; 
#chains in the Genus database with same CATH homology
 4UI5 C;  4L2F C;  4L34 C;  4UI4 C;  4L0T C;  4UI7 C;  4L0S C;  5ADQ B;  4L33 C;  5FPF C;  4L09 C;  4L2G C;  5C5R C;  5ADT B;  5C5Q C;  4L32 C;  4L0B C;  4HLG C;  4L0V C;  4L31 C;  4HLH C;  4HKI C;  4L0I C;  3HJ6 A;  4HL5 C;  4L10 C;  5ADR B;  4HKK B;  5ADS B;  2ZIX B;  4KZL C;  4HMH C;  4L2K C;  4HLF C;  4HLM C;  4UI6 C;  4UI3 C;  5C5P C;  4KZU C;  4KZQ C;  4UVP B;  4HKN C;  4UI8 C;  4HLK C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...