5ADTB

Crystal structure of human tankyrase 2 in complex with od73
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords TANKYRASE-2
publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adtB00
4HL5C 4HLGC 4HLMC 4HLFC 4HKKB 4KZLC 5ADSB 4L32C 4L0BC 4UI8C 5ADTB 4L09C 5C5RC 4UI5C 5C5PC 5ADRB 4HMHC 4L34C 5ADQB 4UI3C 4UI6C 4HKNC 4UI4C 5FPFC 4UI7C 4HLHC 4KZQC 4L0VC 4L10C 4UVPB 4L2GC 4L0TC 4L0IC 4HKIC 4L2FC 4L0SC 4HLKC 4KZUC 4L31C 4L33C 4L2KC 5C5QC
chains in the Genus database with same CATH superfamily
4HL5C 4HLGC 4HLMC 3K33B 4HLFC 4HKKB 4KZLC 5ADSB 4ZLXA 4ZM0A 4L32C 3OEIE 4L0BC 4UI8C 5ADTB 3CTOA 4L09C 5C5RC 4UI5C 3G5OA 5C5PC 5ADRB 4HMHC 4L34C 5ADQB 2A6QA 4UI6C 4UI3C 4ZM2A 4HKNC 3HS2A 4UI4C 5FPFC 3OEIA 4UI7C 4HLHC 4KZQC 4L0VC 3D55A 2ZIXB 4L10C 3HJ6A 4UVPB 4L2GC 4L0TC 4L0IC 4HKIC 4L2FC 4L0SC 4HLKC 2ODKA 4KZUC 4L31C 3K6QA 3KH2E 4L33C 4L2KC 5C5QC 3HRYA
chains in the Genus database with same CATH topology
4HL5C 4HLGC 4HLMC 4HLFC 4HKKB 4KZLC 5ADSB 4L32C 4L0BC 4UI8C 5ADTB 4L09C 5C5RC 4UI5C 5C5PC 5ADRB 4HMHC 4L34C 5ADQB 4UI3C 4UI6C 4HKNC 4UI4C 5FPFC 4UI7C 4HLHC 4KZQC 4L0VC 2ZIXB 4L10C 3HJ6A 4UVPB 4L2GC 4L0TC 4L0IC 4HKIC 4L2FC 4L0SC 4HLKC 4KZUC 4L31C 4L33C 4L2KC 5C5QC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HL5 C;  4HLG C;  4HLM C;  4HLF C;  4HKK B;  4KZL C;  5ADS B;  4L32 C;  4L0B C;  4UI8 C;  5ADT B;  4L09 C;  5C5R C;  4UI5 C;  5C5P C;  5ADR B;  4HMH C;  4L34 C;  5ADQ B;  4UI3 C;  4UI6 C;  4HKN C;  4UI4 C;  5FPF C;  4UI7 C;  4HLH C;  4KZQ C;  4L0V C;  4L10 C;  4UVP B;  4L2G C;  4L0T C;  4L0I C;  4HKI C;  4L2F C;  4L0S C;  4HLK C;  4KZU C;  4L31 C;  4L33 C;  4L2K C;  5C5Q C; 
#chains in the Genus database with same CATH topology
 4HL5 C;  4HLG C;  4HLM C;  3K33 B;  4HLF C;  4HKK B;  4KZL C;  5ADS B;  4ZLX A;  4ZM0 A;  4L32 C;  3OEI E;  4L0B C;  4UI8 C;  5ADT B;  3CTO A;  4L09 C;  5C5R C;  4UI5 C;  3G5O A;  5C5P C;  5ADR B;  4HMH C;  4L34 C;  5ADQ B;  2A6Q A;  4UI6 C;  4UI3 C;  4ZM2 A;  4HKN C;  3HS2 A;  4UI4 C;  5FPF C;  3OEI A;  4UI7 C;  4HLH C;  4KZQ C;  4L0V C;  3D55 A;  2ZIX B;  4L10 C;  3HJ6 A;  4UVP B;  4L2G C;  4L0T C;  4L0I C;  4HKI C;  4L2F C;  4L0S C;  4HLK C;  2ODK A;  4KZU C;  4L31 C;  3K6Q A;  3KH2 E;  4L33 C;  4L2K C;  5C5Q C;  3HRY A; 
#chains in the Genus database with same CATH homology
 4HL5 C;  4HLG C;  4HLM C;  4HLF C;  4HKK B;  4KZL C;  5ADS B;  4L32 C;  4L0B C;  4UI8 C;  5ADT B;  4L09 C;  5C5R C;  4UI5 C;  5C5P C;  5ADR B;  4HMH C;  4L34 C;  5ADQ B;  4UI3 C;  4UI6 C;  4HKN C;  4UI4 C;  5FPF C;  4UI7 C;  4HLH C;  4KZQ C;  4L0V C;  2ZIX B;  4L10 C;  3HJ6 A;  4UVP B;  4L2G C;  4L0T C;  4L0I C;  4HKI C;  4L2F C;  4L0S C;  4HLK C;  4KZU C;  4L31 C;  4L33 C;  4L2K C;  5C5Q C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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