4HKKB

Complex structure of human tankyrase 2 with apigenin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hkkB00
4UI6C 4HLGC 4HLMC 4L2GC 5ADSB 4HL5C 4HLKC 4UI7C 5C5QC 4KZQC 4L32C 4L31C 4HKKB 4L0TC 4L10C 4UI5C 4L0SC 4HLFC 4L0IC 4UI3C 4HKNC 4L34C 4UI8C 5C5PC 4L09C 4UVPB 5ADTB 4HLHC 5C5RC 5ADQB 4KZLC 4UI4C 4L2KC 4HKIC 5ADRB 4L0BC 4L2FC 4L0VC 4HMHC 5FPFC 4KZUC 4L33C
chains in the Genus database with same CATH superfamily
4UI6C 4HLGC 4HLMC 4L2GC 5ADSB 4HL5C 4HLKC 4UI7C 5C5QC 4KZQC 4L32C 2ZIXB 4L31C 4HKKB 4L0TC 4L10C 4UI5C 4ZM0A 3G5OA 3HJ6A 3HRYA 4L0SC 4HLFC 4L0IC 4UI3C 4HKNC 4L34C 4UI8C 4ZM2A 5C5PC 3K33B 3OEIA 4L09C 3HS2A 4UVPB 5ADTB 3OEIE 4HLHC 5C5RC 5ADQB 3K6QA 4KZLC 4UI4C 4L2KC 4HKIC 2ODKA 3D55A 3KH2E 5ADRB 4L0BC 4L2FC 3CTOA 4L0VC 4HMHC 5FPFC 4KZUC 2A6QA 4L33C 4ZLXA
chains in the Genus database with same CATH topology
4UI6C 4HLGC 4HLMC 4L2GC 5ADSB 4HL5C 4HLKC 4UI7C 5C5QC 4KZQC 4L32C 2ZIXB 4L31C 4HKKB 4L0TC 4L10C 4UI5C 3HJ6A 4L0SC 4HLFC 4L0IC 4UI3C 4HKNC 4L34C 4UI8C 5C5PC 4L09C 4UVPB 5ADTB 4HLHC 5C5RC 5ADQB 4KZLC 4UI4C 4L2KC 4HKIC 5ADRB 4L0BC 4L2FC 4L0VC 4HMHC 5FPFC 4KZUC 4L33C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UI6 C;  4HLG C;  4HLM C;  4L2G C;  5ADS B;  4HL5 C;  4HLK C;  4UI7 C;  5C5Q C;  4KZQ C;  4L32 C;  4L31 C;  4HKK B;  4L0T C;  4L10 C;  4UI5 C;  4L0S C;  4HLF C;  4L0I C;  4UI3 C;  4HKN C;  4L34 C;  4UI8 C;  5C5P C;  4L09 C;  4UVP B;  5ADT B;  4HLH C;  5C5R C;  5ADQ B;  4KZL C;  4UI4 C;  4L2K C;  4HKI C;  5ADR B;  4L0B C;  4L2F C;  4L0V C;  4HMH C;  5FPF C;  4KZU C;  4L33 C; 
#chains in the Genus database with same CATH topology
 4UI6 C;  4HLG C;  4HLM C;  4L2G C;  5ADS B;  4HL5 C;  4HLK C;  4UI7 C;  5C5Q C;  4KZQ C;  4L32 C;  2ZIX B;  4L31 C;  4HKK B;  4L0T C;  4L10 C;  4UI5 C;  4ZM0 A;  3G5O A;  3HJ6 A;  3HRY A;  4L0S C;  4HLF C;  4L0I C;  4UI3 C;  4HKN C;  4L34 C;  4UI8 C;  4ZM2 A;  5C5P C;  3K33 B;  3OEI A;  4L09 C;  3HS2 A;  4UVP B;  5ADT B;  3OEI E;  4HLH C;  5C5R C;  5ADQ B;  3K6Q A;  4KZL C;  4UI4 C;  4L2K C;  4HKI C;  2ODK A;  3D55 A;  3KH2 E;  5ADR B;  4L0B C;  4L2F C;  3CTO A;  4L0V C;  4HMH C;  5FPF C;  4KZU C;  2A6Q A;  4L33 C;  4ZLX A; 
#chains in the Genus database with same CATH homology
 4UI6 C;  4HLG C;  4HLM C;  4L2G C;  5ADS B;  4HL5 C;  4HLK C;  4UI7 C;  5C5Q C;  4KZQ C;  4L32 C;  2ZIX B;  4L31 C;  4HKK B;  4L0T C;  4L10 C;  4UI5 C;  3HJ6 A;  4L0S C;  4HLF C;  4L0I C;  4UI3 C;  4HKN C;  4L34 C;  4UI8 C;  5C5P C;  4L09 C;  4UVP B;  5ADT B;  4HLH C;  5C5R C;  5ADQ B;  4KZL C;  4UI4 C;  4L2K C;  4HKI C;  5ADR B;  4L0B C;  4L2F C;  4L0V C;  4HMH C;  5FPF C;  4KZU C;  4L33 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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