4HKKB

Complex structure of human tankyrase 2 with apigenin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hkkB00
4UI6C 4HLGC 4HLHC 4L0TC 4HMHC 4L09C 4L34C 5ADRB 4HKIC 4UI4C 4HLFC 4KZQC 4L10C 4KZLC 4HL5C 4L0BC 5C5PC 4UI3C 4HKNC 5ADTB 4L31C 4UI8C 4KZUC 5FPFC 4UI7C 4L0IC 4L2GC 4HLKC 4L2KC 5C5RC 4L0VC 4UVPB 4HKKB 4L0SC 5ADSB 4HLMC 4L2FC 5C5QC 4L32C 4L33C 5ADQB 4UI5C
chains in the Genus database with same CATH superfamily
4UI6C 4HLGC 4HLHC 4ZM0A 4L0TC 3G5OA 3OEIE 4HMHC 4L09C 4L34C 5ADRB 4HKIC 4UI4C 2ZIXB 3CTOA 4ZLXA 4HLFC 4KZQC 4L10C 3KH2E 4KZLC 3K6QA 4HL5C 4ZM2A 4L0BC 3K33B 5C5PC 4UI3C 3OEIA 4HKNC 5ADTB 2ODKA 4L31C 4UI8C 3HJ6A 3HS2A 4KZUC 5FPFC 4UI7C 4L0IC 4L2GC 4HLKC 4L2KC 5C5RC 4L0VC 4UVPB 2A6QA 4HKKB 4L0SC 5ADSB 3D55A 4HLMC 4L2FC 5C5QC 4L32C 4L33C 5ADQB 3HRYA 4UI5C
chains in the Genus database with same CATH topology
4UI6C 4HLGC 4HLHC 4L0TC 4HMHC 4L09C 4L34C 5ADRB 4HKIC 4UI4C 2ZIXB 4HLFC 4KZQC 4L10C 4KZLC 4HL5C 4L0BC 5C5PC 4UI3C 4HKNC 5ADTB 4L31C 4UI8C 3HJ6A 4KZUC 5FPFC 4UI7C 4L0IC 4L2GC 4HLKC 4L2KC 5C5RC 4L0VC 4UVPB 4HKKB 4L0SC 5ADSB 4HLMC 4L2FC 5C5QC 4L32C 4L33C 5ADQB 4UI5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UI6 C;  4HLG C;  4HLH C;  4L0T C;  4HMH C;  4L09 C;  4L34 C;  5ADR B;  4HKI C;  4UI4 C;  4HLF C;  4KZQ C;  4L10 C;  4KZL C;  4HL5 C;  4L0B C;  5C5P C;  4UI3 C;  4HKN C;  5ADT B;  4L31 C;  4UI8 C;  4KZU C;  5FPF C;  4UI7 C;  4L0I C;  4L2G C;  4HLK C;  4L2K C;  5C5R C;  4L0V C;  4UVP B;  4HKK B;  4L0S C;  5ADS B;  4HLM C;  4L2F C;  5C5Q C;  4L32 C;  4L33 C;  5ADQ B;  4UI5 C; 
#chains in the Genus database with same CATH topology
 4UI6 C;  4HLG C;  4HLH C;  4ZM0 A;  4L0T C;  3G5O A;  3OEI E;  4HMH C;  4L09 C;  4L34 C;  5ADR B;  4HKI C;  4UI4 C;  2ZIX B;  3CTO A;  4ZLX A;  4HLF C;  4KZQ C;  4L10 C;  3KH2 E;  4KZL C;  3K6Q A;  4HL5 C;  4ZM2 A;  4L0B C;  3K33 B;  5C5P C;  4UI3 C;  3OEI A;  4HKN C;  5ADT B;  2ODK A;  4L31 C;  4UI8 C;  3HJ6 A;  3HS2 A;  4KZU C;  5FPF C;  4UI7 C;  4L0I C;  4L2G C;  4HLK C;  4L2K C;  5C5R C;  4L0V C;  4UVP B;  2A6Q A;  4HKK B;  4L0S C;  5ADS B;  3D55 A;  4HLM C;  4L2F C;  5C5Q C;  4L32 C;  4L33 C;  5ADQ B;  3HRY A;  4UI5 C; 
#chains in the Genus database with same CATH homology
 4UI6 C;  4HLG C;  4HLH C;  4L0T C;  4HMH C;  4L09 C;  4L34 C;  5ADR B;  4HKI C;  4UI4 C;  2ZIX B;  4HLF C;  4KZQ C;  4L10 C;  4KZL C;  4HL5 C;  4L0B C;  5C5P C;  4UI3 C;  4HKN C;  5ADT B;  4L31 C;  4UI8 C;  3HJ6 A;  4KZU C;  5FPF C;  4UI7 C;  4L0I C;  4L2G C;  4HLK C;  4L2K C;  5C5R C;  4L0V C;  4UVP B;  4HKK B;  4L0S C;  5ADS B;  4HLM C;  4L2F C;  5C5Q C;  4L32 C;  4L33 C;  5ADQ B;  4UI5 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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