4HKKB

Complex structure of human tankyrase 2 with apigenin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hkkB00
5ADTB 4UI4C 4L2GC 4L09C 4L34C 5C5PC 4HKIC 4L32C 4UI8C 4HLHC 4HLMC 4L31C 5ADQB 5FPFC 4L33C 4L2KC 4HL5C 4KZQC 4L0BC 4UI7C 4L10C 5C5QC 4L0IC 4HLKC 4L0TC 4L0VC 4L2FC 4HKKB 5ADSB 4UI6C 5ADRB 4KZLC 4HMHC 4UI3C 4HLFC 4HKNC 4HLGC 4KZUC 4L0SC 5C5RC 4UI5C 4UVPB
chains in the Genus database with same CATH superfamily
5ADTB 4UI4C 4L2GC 4L09C 4L34C 3OEIE 5C5PC 4ZLXA 4HKIC 4L32C 4ZM0A 3HS2A 4HLHC 4UI8C 3K33B 4HLMC 4L31C 5ADQB 3D55A 3K6QA 5FPFC 2A6QA 4L33C 4L2KC 3CTOA 3HRYA 4HL5C 4KZQC 4L0BC 4UI7C 4L10C 5C5QC 4L0IC 4HLKC 4L0TC 4L0VC 2ZIXB 3HJ6A 3KH2E 4L2FC 2ODKA 4HKKB 5ADSB 3G5OA 4ZM2A 4UI6C 5ADRB 4KZLC 4HMHC 4UI3C 3OEIA 4HLFC 4HKNC 4HLGC 4KZUC 4L0SC 5C5RC 4UI5C 4UVPB
chains in the Genus database with same CATH topology
5ADTB 4UI4C 4L2GC 4L09C 4L34C 5C5PC 4HKIC 4L32C 4UI8C 4HLHC 4HLMC 4L31C 5ADQB 5FPFC 4L33C 4L2KC 4HL5C 4KZQC 4L0BC 4UI7C 4L10C 5C5QC 4L0IC 4HLKC 4L0TC 4L0VC 3HJ6A 2ZIXB 4L2FC 4HKKB 5ADSB 4UI6C 5ADRB 4KZLC 4HMHC 4UI3C 4HLFC 4HKNC 4HLGC 4KZUC 4L0SC 5C5RC 4UI5C 4UVPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4UI4 C;  4L2G C;  4L09 C;  4L34 C;  5C5P C;  4HKI C;  4L32 C;  4UI8 C;  4HLH C;  4HLM C;  4L31 C;  5ADQ B;  5FPF C;  4L33 C;  4L2K C;  4HL5 C;  4KZQ C;  4L0B C;  4UI7 C;  4L10 C;  5C5Q C;  4L0I C;  4HLK C;  4L0T C;  4L0V C;  4L2F C;  4HKK B;  5ADS B;  4UI6 C;  5ADR B;  4KZL C;  4HMH C;  4UI3 C;  4HLF C;  4HKN C;  4HLG C;  4KZU C;  4L0S C;  5C5R C;  4UI5 C;  4UVP B; 
#chains in the Genus database with same CATH topology
 5ADT B;  4UI4 C;  4L2G C;  4L09 C;  4L34 C;  3OEI E;  5C5P C;  4ZLX A;  4HKI C;  4L32 C;  4ZM0 A;  3HS2 A;  4HLH C;  4UI8 C;  3K33 B;  4HLM C;  4L31 C;  5ADQ B;  3D55 A;  3K6Q A;  5FPF C;  2A6Q A;  4L33 C;  4L2K C;  3CTO A;  3HRY A;  4HL5 C;  4KZQ C;  4L0B C;  4UI7 C;  4L10 C;  5C5Q C;  4L0I C;  4HLK C;  4L0T C;  4L0V C;  2ZIX B;  3HJ6 A;  3KH2 E;  4L2F C;  2ODK A;  4HKK B;  5ADS B;  3G5O A;  4ZM2 A;  4UI6 C;  5ADR B;  4KZL C;  4HMH C;  4UI3 C;  3OEI A;  4HLF C;  4HKN C;  4HLG C;  4KZU C;  4L0S C;  5C5R C;  4UI5 C;  4UVP B; 
#chains in the Genus database with same CATH homology
 5ADT B;  4UI4 C;  4L2G C;  4L09 C;  4L34 C;  5C5P C;  4HKI C;  4L32 C;  4UI8 C;  4HLH C;  4HLM C;  4L31 C;  5ADQ B;  5FPF C;  4L33 C;  4L2K C;  4HL5 C;  4KZQ C;  4L0B C;  4UI7 C;  4L10 C;  5C5Q C;  4L0I C;  4HLK C;  4L0T C;  4L0V C;  3HJ6 A;  2ZIX B;  4L2F C;  4HKK B;  5ADS B;  4UI6 C;  5ADR B;  4KZL C;  4HMH C;  4UI3 C;  4HLF C;  4HKN C;  4HLG C;  4KZU C;  4L0S C;  5C5R C;  4UI5 C;  4UVP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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