4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
4UI4C 5C5RC 4KZQC 4HLKC 4HLHC 4HKNC 4L09C 4L2KC 4L33C 4L10C 4UI5C 4HLGC 4UVPB 5ADSB 5ADTB 4L2FC 4L0BC 4L0VC 4L0SC 4UI3C 4KZUC 4KZLC 4L0IC 4UI6C 4HL5C 4L34C 4L2GC 4HLFC 4HKKB 4HLMC 4UI7C 5C5PC 5ADQB 4L31C 4UI8C 4HMHC 5ADRB 5C5QC 4HKIC 4L32C 5FPFC 4L0TC
chains in the Genus database with same CATH superfamily
4L0TC 4UI4C 5C5RC 4KZQC 4HLKC 2A6QA 4HLHC 4HKNC 4L09C 4L2KC 2ZIXB 4L33C 4L10C 4UI5C 4ZM2A 4HLGC 3OEIE 3G5OA 3HS2A 4UVPB 5ADSB 3D55A 2ODKA 4L2FC 4L0BC 4L0VC 4L0SC 4UI3C 5ADTB 4ZLXA 4KZLC 4KZUC 3OEIA 4ZM0A 4L0IC 3CTOA 4UI6C 4HL5C 3KH2E 4L34C 4L2GC 4HLFC 3HJ6A 4HKKB 4HLMC 4UI7C 5C5PC 5ADQB 4L31C 4UI8C 4HMHC 5ADRB 3HRYA 5C5QC 4HKIC 4L32C 5FPFC 3K6QA 3K33B
chains in the Genus database with same CATH topology
4L0TC 4UI4C 5C5RC 4KZQC 4HLKC 4HLHC 4HKNC 4L09C 4L2KC 2ZIXB 4L33C 4L10C 4UI5C 4HLGC 4UVPB 5ADSB 5ADTB 4L2FC 4L0BC 4L0VC 4L0SC 4UI3C 4KZUC 4KZLC 4L0IC 4UI6C 4HL5C 4L34C 4HLFC 3HJ6A 4HKKB 4HLMC 4UI7C 5C5PC 5ADQB 4L31C 4UI8C 4HMHC 5ADRB 5C5QC 4HKIC 4L32C 5FPFC 4L2GC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UI4 C;  5C5R C;  4KZQ C;  4HLK C;  4HLH C;  4HKN C;  4L09 C;  4L2K C;  4L33 C;  4L10 C;  4UI5 C;  4HLG C;  4UVP B;  5ADS B;  5ADT B;  4L2F C;  4L0B C;  4L0V C;  4L0S C;  4UI3 C;  4KZU C;  4KZL C;  4L0I C;  4UI6 C;  4HL5 C;  4L34 C;  4L2G C;  4HLF C;  4HKK B;  4HLM C;  4UI7 C;  5C5P C;  5ADQ B;  4L31 C;  4UI8 C;  4HMH C;  5ADR B;  5C5Q C;  4HKI C;  4L32 C;  5FPF C;  4L0T C; 
#chains in the Genus database with same CATH topology
 4L0T C;  4UI4 C;  5C5R C;  4KZQ C;  4HLK C;  2A6Q A;  4HLH C;  4HKN C;  4L09 C;  4L2K C;  2ZIX B;  4L33 C;  4L10 C;  4UI5 C;  4ZM2 A;  4HLG C;  3OEI E;  3G5O A;  3HS2 A;  4UVP B;  5ADS B;  3D55 A;  2ODK A;  4L2F C;  4L0B C;  4L0V C;  4L0S C;  4UI3 C;  5ADT B;  4ZLX A;  4KZL C;  4KZU C;  3OEI A;  4ZM0 A;  4L0I C;  3CTO A;  4UI6 C;  4HL5 C;  3KH2 E;  4L34 C;  4L2G C;  4HLF C;  3HJ6 A;  4HKK B;  4HLM C;  4UI7 C;  5C5P C;  5ADQ B;  4L31 C;  4UI8 C;  4HMH C;  5ADR B;  3HRY A;  5C5Q C;  4HKI C;  4L32 C;  5FPF C;  3K6Q A;  3K33 B; 
#chains in the Genus database with same CATH homology
 4L0T C;  4UI4 C;  5C5R C;  4KZQ C;  4HLK C;  4HLH C;  4HKN C;  4L09 C;  4L2K C;  2ZIX B;  4L33 C;  4L10 C;  4UI5 C;  4HLG C;  4UVP B;  5ADS B;  5ADT B;  4L2F C;  4L0B C;  4L0V C;  4L0S C;  4UI3 C;  4KZU C;  4KZL C;  4L0I C;  4UI6 C;  4HL5 C;  4L34 C;  4HLF C;  3HJ6 A;  4HKK B;  4HLM C;  4UI7 C;  5C5P C;  5ADQ B;  4L31 C;  4UI8 C;  4HMH C;  5ADR B;  5C5Q C;  4HKI C;  4L32 C;  5FPF C;  4L2G C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...