4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
5ADTB 4HKNC 5C5RC 4L32C 4UI6C 4HLGC 4L0VC 4L31C 5FPFC 4HLMC 4HKIC 4L33C 4L34C 4L09C 4HKKB 4UVPB 5ADRB 4UI4C 4HLKC 4HLHC 4L0SC 4KZUC 4UI3C 4KZLC 4L0TC 4UI7C 5C5PC 4HMHC 4HL5C 4L0BC 4L2GC 4UI8C 4UI5C 4L2FC 5ADSB 4L0IC 5ADQB 4L10C 4KZQC 4HLFC 4L2KC 5C5QC
chains in the Genus database with same CATH superfamily
4ZM0A 5ADTB 4HKNC 5C5RC 4L32C 4UI6C 4HLGC 4L0VC 4L31C 5FPFC 4HLMC 2ODKA 4HKIC 2ZIXB 4L33C 4ZM2A 4ZLXA 4L34C 3OEIE 4L09C 4HKKB 4UVPB 5ADRB 4UI4C 3HRYA 3HJ6A 3CTOA 4HLKC 4HLHC 4L0SC 4KZUC 4UI3C 4KZLC 4L0TC 4UI7C 3KH2E 5C5PC 4HMHC 4HL5C 3G5OA 3OEIA 4L0BC 4L2GC 3K6QA 3HS2A 4UI8C 3D55A 4L2FC 4UI5C 4L0IC 5ADSB 5ADQB 3K33B 2A6QA 4L10C 4KZQC 4HLFC 4L2KC 5C5QC
chains in the Genus database with same CATH topology
5ADTB 4HKNC 5C5RC 4L32C 4UI6C 4HLGC 4L0VC 4L31C 5FPFC 4HLMC 4HKIC 2ZIXB 4L33C 4L34C 4L09C 4HKKB 4UVPB 5ADRB 4UI4C 3HJ6A 4HLKC 4HLHC 4L0SC 4KZUC 4UI3C 4KZLC 4L0TC 4UI7C 5C5PC 4HMHC 4HL5C 4L0BC 4L2GC 4UI8C 4UI5C 4L2FC 5ADSB 4L0IC 5ADQB 4L10C 4KZQC 4HLFC 4L2KC 5C5QC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4HKN C;  5C5R C;  4L32 C;  4UI6 C;  4HLG C;  4L0V C;  4L31 C;  5FPF C;  4HLM C;  4HKI C;  4L33 C;  4L34 C;  4L09 C;  4HKK B;  4UVP B;  5ADR B;  4UI4 C;  4HLK C;  4HLH C;  4L0S C;  4KZU C;  4UI3 C;  4KZL C;  4L0T C;  4UI7 C;  5C5P C;  4HMH C;  4HL5 C;  4L0B C;  4L2G C;  4UI8 C;  4UI5 C;  4L2F C;  5ADS B;  4L0I C;  5ADQ B;  4L10 C;  4KZQ C;  4HLF C;  4L2K C;  5C5Q C; 
#chains in the Genus database with same CATH topology
 4ZM0 A;  5ADT B;  4HKN C;  5C5R C;  4L32 C;  4UI6 C;  4HLG C;  4L0V C;  4L31 C;  5FPF C;  4HLM C;  2ODK A;  4HKI C;  2ZIX B;  4L33 C;  4ZM2 A;  4ZLX A;  4L34 C;  3OEI E;  4L09 C;  4HKK B;  4UVP B;  5ADR B;  4UI4 C;  3HRY A;  3HJ6 A;  3CTO A;  4HLK C;  4HLH C;  4L0S C;  4KZU C;  4UI3 C;  4KZL C;  4L0T C;  4UI7 C;  3KH2 E;  5C5P C;  4HMH C;  4HL5 C;  3G5O A;  3OEI A;  4L0B C;  4L2G C;  3K6Q A;  3HS2 A;  4UI8 C;  3D55 A;  4L2F C;  4UI5 C;  4L0I C;  5ADS B;  5ADQ B;  3K33 B;  2A6Q A;  4L10 C;  4KZQ C;  4HLF C;  4L2K C;  5C5Q C; 
#chains in the Genus database with same CATH homology
 5ADT B;  4HKN C;  5C5R C;  4L32 C;  4UI6 C;  4HLG C;  4L0V C;  4L31 C;  5FPF C;  4HLM C;  4HKI C;  2ZIX B;  4L33 C;  4L34 C;  4L09 C;  4HKK B;  4UVP B;  5ADR B;  4UI4 C;  3HJ6 A;  4HLK C;  4HLH C;  4L0S C;  4KZU C;  4UI3 C;  4KZL C;  4L0T C;  4UI7 C;  5C5P C;  4HMH C;  4HL5 C;  4L0B C;  4L2G C;  4UI8 C;  4UI5 C;  4L2F C;  5ADS B;  4L0I C;  5ADQ B;  4L10 C;  4KZQ C;  4HLF C;  4L2K C;  5C5Q C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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