4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
5ADTB 4HLHC 4UI7C 4L0IC 4HLKC 4L31C 4L0SC 4KZUC 5ADSB 4KZQC 4UI3C 4UI8C 4HLFC 4L32C 4L34C 4HKKB 4HKIC 4HMHC 4UI6C 4L0VC 5C5PC 4L33C 5C5QC 4HKNC 4L0BC 4UVPB 4KZLC 4UI4C 4L2KC 5ADQB 4HL5C 4L10C 4L2FC 4HLGC 5ADRB 4L2GC 4HLMC 4UI5C 4L09C 5FPFC 4L0TC 5C5RC
chains in the Genus database with same CATH superfamily
5ADTB 4HLHC 4UI7C 4L0IC 4HLKC 4L31C 4L0SC 4KZUC 5ADSB 3HS2A 4KZQC 2ZIXB 4UI3C 3OEIE 4UI8C 3D55A 4HLFC 3HJ6A 4L32C 4ZM2A 3KH2E 4ZLXA 4L34C 3K33B 4HKKB 4HKIC 4HMHC 3K6QA 3OEIA 4UI6C 4L0VC 5C5PC 4L33C 5C5QC 4HKNC 4L0BC 2ODKA 4ZM0A 2A6QA 4UVPB 4KZLC 4UI4C 4L2KC 5ADQB 4HL5C 3G5OA 4L10C 4L2FC 4HLGC 5ADRB 4L2GC 4HLMC 4UI5C 3HRYA 4L09C 4L0TC 5FPFC 3CTOA 5C5RC
chains in the Genus database with same CATH topology
5ADTB 4HLHC 4UI7C 4L0IC 4HLKC 4L31C 4L0SC 4KZUC 5ADSB 4KZQC 2ZIXB 4UI3C 4UI8C 4HLFC 3HJ6A 4L32C 4L34C 4HKKB 4HKIC 4HMHC 4UI6C 4L0VC 5C5PC 4L33C 5C5QC 4HKNC 4L0BC 4UVPB 4KZLC 4UI4C 4L2KC 5ADQB 4HL5C 4L10C 4L2FC 4HLGC 5ADRB 4L2GC 4HLMC 4UI5C 4L09C 5FPFC 4L0TC 5C5RC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4HLH C;  4UI7 C;  4L0I C;  4HLK C;  4L31 C;  4L0S C;  4KZU C;  5ADS B;  4KZQ C;  4UI3 C;  4UI8 C;  4HLF C;  4L32 C;  4L34 C;  4HKK B;  4HKI C;  4HMH C;  4UI6 C;  4L0V C;  5C5P C;  4L33 C;  5C5Q C;  4HKN C;  4L0B C;  4UVP B;  4KZL C;  4UI4 C;  4L2K C;  5ADQ B;  4HL5 C;  4L10 C;  4L2F C;  4HLG C;  5ADR B;  4L2G C;  4HLM C;  4UI5 C;  4L09 C;  5FPF C;  4L0T C;  5C5R C; 
#chains in the Genus database with same CATH topology
 5ADT B;  4HLH C;  4UI7 C;  4L0I C;  4HLK C;  4L31 C;  4L0S C;  4KZU C;  5ADS B;  3HS2 A;  4KZQ C;  2ZIX B;  4UI3 C;  3OEI E;  4UI8 C;  3D55 A;  4HLF C;  3HJ6 A;  4L32 C;  4ZM2 A;  3KH2 E;  4ZLX A;  4L34 C;  3K33 B;  4HKK B;  4HKI C;  4HMH C;  3K6Q A;  3OEI A;  4UI6 C;  4L0V C;  5C5P C;  4L33 C;  5C5Q C;  4HKN C;  4L0B C;  2ODK A;  4ZM0 A;  2A6Q A;  4UVP B;  4KZL C;  4UI4 C;  4L2K C;  5ADQ B;  4HL5 C;  3G5O A;  4L10 C;  4L2F C;  4HLG C;  5ADR B;  4L2G C;  4HLM C;  4UI5 C;  3HRY A;  4L09 C;  4L0T C;  5FPF C;  3CTO A;  5C5R C; 
#chains in the Genus database with same CATH homology
 5ADT B;  4HLH C;  4UI7 C;  4L0I C;  4HLK C;  4L31 C;  4L0S C;  4KZU C;  5ADS B;  4KZQ C;  2ZIX B;  4UI3 C;  4UI8 C;  4HLF C;  3HJ6 A;  4L32 C;  4L34 C;  4HKK B;  4HKI C;  4HMH C;  4UI6 C;  4L0V C;  5C5P C;  4L33 C;  5C5Q C;  4HKN C;  4L0B C;  4UVP B;  4KZL C;  4UI4 C;  4L2K C;  5ADQ B;  4HL5 C;  4L10 C;  4L2F C;  4HLG C;  5ADR B;  4L2G C;  4HLM C;  4UI5 C;  4L09 C;  5FPF C;  4L0T C;  5C5R C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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