4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
5C5PC 4L32C 4HKIC 4HMHC 4UI3C 4L0IC 4L0VC 4L31C 4UI5C 4HLGC 4HLMC 4KZQC 4UI8C 4KZLC 4KZUC 4UI6C 4HLFC 4L0TC 5ADRB 4L2KC 4L2GC 4HLKC 4L10C 4L09C 4L33C 5C5RC 5ADSB 4L2FC 5C5QC 4UI7C 4HKNC 5ADTB 4L34C 4L0BC 4UVPB 4HL5C 5ADQB 4HKKB 4HLHC 4UI4C 4L0SC 5FPFC
chains in the Genus database with same CATH superfamily
5C5PC 2A6QA 3D55A 4L32C 3K6QA 4HKIC 4HMHC 4ZM2A 3OEIA 4UI3C 4L0IC 4L0VC 4L31C 4ZM0A 3HRYA 4UI5C 4ZLXA 3CTOA 4HLGC 2ZIXB 3OEIE 4HLMC 4KZQC 4UI8C 4KZLC 4KZUC 4UI6C 4HLFC 4L0TC 5ADRB 4L2KC 4L2GC 4HLKC 4L10C 4L09C 3HS2A 4L33C 5C5RC 5ADSB 4L2FC 5C5QC 4UI7C 3G5OA 4HKNC 5ADTB 4L34C 4L0BC 4UVPB 3HJ6A 2ODKA 3K33B 4HL5C 3KH2E 5ADQB 4HKKB 4HLHC 4UI4C 4L0SC 5FPFC
chains in the Genus database with same CATH topology
5C5PC 4L32C 4HKIC 4HMHC 4UI3C 4L0IC 4L0VC 4L31C 4UI5C 4HLGC 2ZIXB 4HLMC 4KZQC 4UI8C 4KZLC 4KZUC 4UI6C 4HLFC 4L0TC 5ADRB 4L2KC 4L2GC 4HLKC 4L10C 4L09C 4L33C 5C5RC 5ADSB 4L2FC 5C5QC 4UI7C 4HKNC 5ADTB 4L34C 4L0BC 4UVPB 3HJ6A 4HL5C 5ADQB 4HKKB 4HLHC 4UI4C 4L0SC 5FPFC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5P C;  4L32 C;  4HKI C;  4HMH C;  4UI3 C;  4L0I C;  4L0V C;  4L31 C;  4UI5 C;  4HLG C;  4HLM C;  4KZQ C;  4UI8 C;  4KZL C;  4KZU C;  4UI6 C;  4HLF C;  4L0T C;  5ADR B;  4L2K C;  4L2G C;  4HLK C;  4L10 C;  4L09 C;  4L33 C;  5C5R C;  5ADS B;  4L2F C;  5C5Q C;  4UI7 C;  4HKN C;  5ADT B;  4L34 C;  4L0B C;  4UVP B;  4HL5 C;  5ADQ B;  4HKK B;  4HLH C;  4UI4 C;  4L0S C;  5FPF C; 
#chains in the Genus database with same CATH topology
 5C5P C;  2A6Q A;  3D55 A;  4L32 C;  3K6Q A;  4HKI C;  4HMH C;  4ZM2 A;  3OEI A;  4UI3 C;  4L0I C;  4L0V C;  4L31 C;  4ZM0 A;  3HRY A;  4UI5 C;  4ZLX A;  3CTO A;  4HLG C;  2ZIX B;  3OEI E;  4HLM C;  4KZQ C;  4UI8 C;  4KZL C;  4KZU C;  4UI6 C;  4HLF C;  4L0T C;  5ADR B;  4L2K C;  4L2G C;  4HLK C;  4L10 C;  4L09 C;  3HS2 A;  4L33 C;  5C5R C;  5ADS B;  4L2F C;  5C5Q C;  4UI7 C;  3G5O A;  4HKN C;  5ADT B;  4L34 C;  4L0B C;  4UVP B;  3HJ6 A;  2ODK A;  3K33 B;  4HL5 C;  3KH2 E;  5ADQ B;  4HKK B;  4HLH C;  4UI4 C;  4L0S C;  5FPF C; 
#chains in the Genus database with same CATH homology
 5C5P C;  4L32 C;  4HKI C;  4HMH C;  4UI3 C;  4L0I C;  4L0V C;  4L31 C;  4UI5 C;  4HLG C;  2ZIX B;  4HLM C;  4KZQ C;  4UI8 C;  4KZL C;  4KZU C;  4UI6 C;  4HLF C;  4L0T C;  5ADR B;  4L2K C;  4L2G C;  4HLK C;  4L10 C;  4L09 C;  4L33 C;  5C5R C;  5ADS B;  4L2F C;  5C5Q C;  4UI7 C;  4HKN C;  5ADT B;  4L34 C;  4L0B C;  4UVP B;  3HJ6 A;  4HL5 C;  5ADQ B;  4HKK B;  4HLH C;  4UI4 C;  4L0S C;  5FPF C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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