4HL5C

Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hl5C00
4HKIC 4KZLC 4L32C 5FPFC 4HKKB 4UI6C 4HLMC 4HMHC 4HLKC 4UI5C 5C5QC 4KZUC 4L2GC 4L10C 4UVPB 4L09C 5ADQB 4L2KC 5C5PC 4KZQC 4L0SC 4HLHC 4L2FC 4L0TC 4HLGC 5C5RC 4L34C 5ADRB 4L0BC 4UI4C 5ADTB 4L0IC 4L33C 4HL5C 4L0VC 4L31C 4UI3C 4UI7C 5ADSB 4UI8C 4HKNC 4HLFC
chains in the Genus database with same CATH superfamily
4HKIC 3OEIA 4KZLC 3D55A 4L32C 5FPFC 3G5OA 4HKKB 4UI6C 3OEIE 2ZIXB 2A6QA 3HS2A 2ODKA 3K6QA 4HLMC 4HLKC 4HMHC 4UI5C 5C5QC 4KZUC 4L2GC 4L10C 4UVPB 3K33B 4L09C 5ADQB 4L2KC 5C5PC 4KZQC 4L0SC 4HLHC 4L2FC 4L0TC 4HLGC 5C5RC 4L34C 4ZM0A 5ADRB 4L0BC 4UI4C 5ADTB 4L0IC 4ZM2A 3HJ6A 3CTOA 3HRYA 4L33C 4ZLXA 4HL5C 4L0VC 4L31C 3KH2E 4UI3C 4UI7C 5ADSB 4UI8C 4HKNC 4HLFC
chains in the Genus database with same CATH topology
4HKIC 4KZLC 4L32C 5FPFC 4HKKB 4UI6C 2ZIXB 4HLMC 4HLKC 4HMHC 4UI5C 5C5QC 4KZUC 4L2GC 4L10C 4UVPB 4L09C 5ADQB 4L2KC 5C5PC 4KZQC 4L0SC 4HLHC 4L2FC 4L0TC 4HLGC 5C5RC 4L34C 5ADRB 4L0BC 4UI4C 5ADTB 4L0IC 3HJ6A 4L33C 4HL5C 4L0VC 4L31C 4UI3C 4UI7C 5ADSB 4UI8C 4HKNC 4HLFC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKI C;  4KZL C;  4L32 C;  5FPF C;  4HKK B;  4UI6 C;  4HLM C;  4HMH C;  4HLK C;  4UI5 C;  5C5Q C;  4KZU C;  4L2G C;  4L10 C;  4UVP B;  4L09 C;  5ADQ B;  4L2K C;  5C5P C;  4KZQ C;  4L0S C;  4HLH C;  4L2F C;  4L0T C;  4HLG C;  5C5R C;  4L34 C;  5ADR B;  4L0B C;  4UI4 C;  5ADT B;  4L0I C;  4L33 C;  4HL5 C;  4L0V C;  4L31 C;  4UI3 C;  4UI7 C;  5ADS B;  4UI8 C;  4HKN C;  4HLF C; 
#chains in the Genus database with same CATH topology
 4HKI C;  3OEI A;  4KZL C;  3D55 A;  4L32 C;  5FPF C;  3G5O A;  4HKK B;  4UI6 C;  3OEI E;  2ZIX B;  2A6Q A;  3HS2 A;  2ODK A;  3K6Q A;  4HLM C;  4HLK C;  4HMH C;  4UI5 C;  5C5Q C;  4KZU C;  4L2G C;  4L10 C;  4UVP B;  3K33 B;  4L09 C;  5ADQ B;  4L2K C;  5C5P C;  4KZQ C;  4L0S C;  4HLH C;  4L2F C;  4L0T C;  4HLG C;  5C5R C;  4L34 C;  4ZM0 A;  5ADR B;  4L0B C;  4UI4 C;  5ADT B;  4L0I C;  4ZM2 A;  3HJ6 A;  3CTO A;  3HRY A;  4L33 C;  4ZLX A;  4HL5 C;  4L0V C;  4L31 C;  3KH2 E;  4UI3 C;  4UI7 C;  5ADS B;  4UI8 C;  4HKN C;  4HLF C; 
#chains in the Genus database with same CATH homology
 4HKI C;  4KZL C;  4L32 C;  5FPF C;  4HKK B;  4UI6 C;  2ZIX B;  4HLM C;  4HLK C;  4HMH C;  4UI5 C;  5C5Q C;  4KZU C;  4L2G C;  4L10 C;  4UVP B;  4L09 C;  5ADQ B;  4L2K C;  5C5P C;  4KZQ C;  4L0S C;  4HLH C;  4L2F C;  4L0T C;  4HLG C;  5C5R C;  4L34 C;  5ADR B;  4L0B C;  4UI4 C;  5ADT B;  4L0I C;  3HJ6 A;  4L33 C;  4HL5 C;  4L0V C;  4L31 C;  4UI3 C;  4UI7 C;  5ADS B;  4UI8 C;  4HKN C;  4HLF C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...