4HL5C

Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hl5C00
4HLKC 4L10C 4HL5C 4HKKB 4L0TC 4L0SC 5C5QC 4HMHC 4KZLC 4L0VC 4L0IC 5FPFC 4UI8C 5ADRB 4L34C 4HLFC 4L2KC 4UI6C 4L33C 5C5PC 4UVPB 4HKIC 4HKNC 4L0BC 4L32C 4UI5C 4L2FC 4L2GC 5C5RC 4HLMC 4KZQC 5ADSB 4KZUC 4L09C 4UI3C 4HLGC 4UI7C 5ADQB 5ADTB 4UI4C 4HLHC 4L31C
chains in the Genus database with same CATH superfamily
4HLKC 4L10C 4HL5C 4HKKB 3K33B 3K6QA 4L0TC 4ZM0A 2ODKA 3OEIE 4L0SC 4HMHC 5C5QC 4KZLC 4L0VC 4L0IC 5FPFC 4UI8C 5ADRB 4L34C 4HLFC 3CTOA 4L2KC 4L33C 4UI6C 5C5PC 4UVPB 4HKIC 4HKNC 4L0BC 3KH2E 3HJ6A 2ZIXB 4L32C 4UI5C 4L2FC 4L2GC 5C5RC 3OEIA 4HLMC 4KZQC 4ZM2A 5ADSB 3D55A 3HS2A 4KZUC 4L09C 4UI3C 4HLGC 4UI7C 5ADQB 5ADTB 4ZLXA 3HRYA 4HLHC 4UI4C 2A6QA 4L31C 3G5OA
chains in the Genus database with same CATH topology
4HLKC 4L10C 4HL5C 4HKKB 4L0TC 4L0SC 5C5QC 4HMHC 4KZLC 4L0VC 4L0IC 5FPFC 4UI8C 5ADRB 4L34C 4HLFC 4L2KC 4UI6C 4L33C 5C5PC 4UVPB 4HKIC 4HKNC 4L0BC 3HJ6A 2ZIXB 4L32C 4UI5C 4L2FC 4L2GC 5C5RC 4HLMC 4KZQC 5ADSB 4KZUC 4L09C 4UI3C 4HLGC 4UI7C 5ADQB 5ADTB 4UI4C 4HLHC 4L31C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HLK C;  4L10 C;  4HL5 C;  4HKK B;  4L0T C;  4L0S C;  5C5Q C;  4HMH C;  4KZL C;  4L0V C;  4L0I C;  5FPF C;  4UI8 C;  5ADR B;  4L34 C;  4HLF C;  4L2K C;  4UI6 C;  4L33 C;  5C5P C;  4UVP B;  4HKI C;  4HKN C;  4L0B C;  4L32 C;  4UI5 C;  4L2F C;  4L2G C;  5C5R C;  4HLM C;  4KZQ C;  5ADS B;  4KZU C;  4L09 C;  4UI3 C;  4HLG C;  4UI7 C;  5ADQ B;  5ADT B;  4UI4 C;  4HLH C;  4L31 C; 
#chains in the Genus database with same CATH topology
 4HLK C;  4L10 C;  4HL5 C;  4HKK B;  3K33 B;  3K6Q A;  4L0T C;  4ZM0 A;  2ODK A;  3OEI E;  4L0S C;  4HMH C;  5C5Q C;  4KZL C;  4L0V C;  4L0I C;  5FPF C;  4UI8 C;  5ADR B;  4L34 C;  4HLF C;  3CTO A;  4L2K C;  4L33 C;  4UI6 C;  5C5P C;  4UVP B;  4HKI C;  4HKN C;  4L0B C;  3KH2 E;  3HJ6 A;  2ZIX B;  4L32 C;  4UI5 C;  4L2F C;  4L2G C;  5C5R C;  3OEI A;  4HLM C;  4KZQ C;  4ZM2 A;  5ADS B;  3D55 A;  3HS2 A;  4KZU C;  4L09 C;  4UI3 C;  4HLG C;  4UI7 C;  5ADQ B;  5ADT B;  4ZLX A;  3HRY A;  4HLH C;  4UI4 C;  2A6Q A;  4L31 C;  3G5O A; 
#chains in the Genus database with same CATH homology
 4HLK C;  4L10 C;  4HL5 C;  4HKK B;  4L0T C;  4L0S C;  5C5Q C;  4HMH C;  4KZL C;  4L0V C;  4L0I C;  5FPF C;  4UI8 C;  5ADR B;  4L34 C;  4HLF C;  4L2K C;  4UI6 C;  4L33 C;  5C5P C;  4UVP B;  4HKI C;  4HKN C;  4L0B C;  3HJ6 A;  2ZIX B;  4L32 C;  4UI5 C;  4L2F C;  4L2G C;  5C5R C;  4HLM C;  4KZQ C;  5ADS B;  4KZU C;  4L09 C;  4UI3 C;  4HLG C;  4UI7 C;  5ADQ B;  5ADT B;  4UI4 C;  4HLH C;  4L31 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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