4HLGC

Crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlgC00
5C5QC 4L2GC 4KZLC 4L09C 5FPFC 4UI7C 5C5RC 4HLMC 4UI6C 4L31C 5ADSB 4L0SC 4L0BC 4L0VC 5ADTB 4HKIC 4KZQC 4HLFC 4HMHC 4L2FC 4HKNC 4L0IC 4HL5C 4L0TC 5ADQB 4L2KC 4L32C 5ADRB 4UI4C 5C5PC 4KZUC 4L33C 4HLKC 4UI5C 4HKKB 4HLGC 4L10C 4L34C 4UI8C 4UVPB 4HLHC 4UI3C
chains in the Genus database with same CATH superfamily
5C5QC 4L2GC 4KZLC 4L09C 5FPFC 3CTOA 4UI7C 5C5RC 4HLMC 2ZIXB 4UI6C 4L31C 5ADSB 3HJ6A 4ZLXA 4L0SC 4ZM2A 4L0BC 4L0VC 5ADTB 4HKIC 4KZQC 3G5OA 4HLFC 4HMHC 4L2FC 4HKNC 4L0IC 3OEIA 3K33B 3OEIE 4HL5C 4L0TC 5ADQB 4L2KC 3K6QA 4L32C 3HS2A 5ADRB 2A6QA 2ODKA 4UI4C 5C5PC 4KZUC 4L33C 4HLKC 4UI5C 4ZM0A 3D55A 3KH2E 3HRYA 4HKKB 4HLGC 4L10C 4L34C 4UI8C 4UVPB 4HLHC 4UI3C
chains in the Genus database with same CATH topology
5C5QC 4L2GC 4KZLC 4L09C 5FPFC 4UI7C 5C5RC 4HLMC 2ZIXB 4UI6C 4L31C 5ADSB 3HJ6A 4L0SC 4L0BC 4L0VC 5ADTB 4HKIC 4KZQC 4HLFC 4HMHC 4L2FC 4HKNC 4L0IC 4HL5C 4L0TC 5ADQB 4L2KC 4L32C 5ADRB 4UI4C 5C5PC 4KZUC 4L33C 4HLKC 4UI5C 4HKKB 4HLGC 4L10C 4L34C 4UI8C 4UVPB 4HLHC 4UI3C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5Q C;  4L2G C;  4KZL C;  4L09 C;  5FPF C;  4UI7 C;  5C5R C;  4HLM C;  4UI6 C;  4L31 C;  5ADS B;  4L0S C;  4L0B C;  4L0V C;  5ADT B;  4HKI C;  4KZQ C;  4HLF C;  4HMH C;  4L2F C;  4HKN C;  4L0I C;  4HL5 C;  4L0T C;  5ADQ B;  4L2K C;  4L32 C;  5ADR B;  4UI4 C;  5C5P C;  4KZU C;  4L33 C;  4HLK C;  4UI5 C;  4HKK B;  4HLG C;  4L10 C;  4L34 C;  4UI8 C;  4UVP B;  4HLH C;  4UI3 C; 
#chains in the Genus database with same CATH topology
 5C5Q C;  4L2G C;  4KZL C;  4L09 C;  5FPF C;  3CTO A;  4UI7 C;  5C5R C;  4HLM C;  2ZIX B;  4UI6 C;  4L31 C;  5ADS B;  3HJ6 A;  4ZLX A;  4L0S C;  4ZM2 A;  4L0B C;  4L0V C;  5ADT B;  4HKI C;  4KZQ C;  3G5O A;  4HLF C;  4HMH C;  4L2F C;  4HKN C;  4L0I C;  3OEI A;  3K33 B;  3OEI E;  4HL5 C;  4L0T C;  5ADQ B;  4L2K C;  3K6Q A;  4L32 C;  3HS2 A;  5ADR B;  2A6Q A;  2ODK A;  4UI4 C;  5C5P C;  4KZU C;  4L33 C;  4HLK C;  4UI5 C;  4ZM0 A;  3D55 A;  3KH2 E;  3HRY A;  4HKK B;  4HLG C;  4L10 C;  4L34 C;  4UI8 C;  4UVP B;  4HLH C;  4UI3 C; 
#chains in the Genus database with same CATH homology
 5C5Q C;  4L2G C;  4KZL C;  4L09 C;  5FPF C;  4UI7 C;  5C5R C;  4HLM C;  2ZIX B;  4UI6 C;  4L31 C;  5ADS B;  3HJ6 A;  4L0S C;  4L0B C;  4L0V C;  5ADT B;  4HKI C;  4KZQ C;  4HLF C;  4HMH C;  4L2F C;  4HKN C;  4L0I C;  4HL5 C;  4L0T C;  5ADQ B;  4L2K C;  4L32 C;  5ADR B;  4UI4 C;  5C5P C;  4KZU C;  4L33 C;  4HLK C;  4UI5 C;  4HKK B;  4HLG C;  4L10 C;  4L34 C;  4UI8 C;  4UVP B;  4HLH C;  4UI3 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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