4HLGC

Crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlgC00
4HMHC 4HL5C 4L0VC 4L32C 4L31C 4L0SC 4UI3C 4HLKC 4L2FC 4KZUC 4UI4C 4HKNC 4KZLC 5ADRB 4L0TC 4UI6C 5ADSB 4KZQC 4L0IC 4L09C 4UI8C 4HLMC 4L34C 4L0BC 4HLGC 4L2KC 5ADQB 4UI5C 4UI7C 5C5QC 4HLFC 5C5PC 4HLHC 5FPFC 4L33C 4HKIC 4HKKB 4L10C 4L2GC 4UVPB 5C5RC 5ADTB
chains in the Genus database with same CATH superfamily
4HMHC 3K33B 4HL5C 4ZM0A 4L0VC 2ODKA 3OEIE 2A6QA 3G5OA 4L31C 4L0SC 4L32C 4HLKC 4UI3C 3D55A 4ZM2A 4L2FC 4KZUC 4UI4C 4HKNC 4KZLC 3K6QA 5ADRB 4L0TC 4UI6C 5ADSB 4KZQC 4L0IC 4L09C 4UI8C 4HLMC 4L34C 3HS2A 4L0BC 4HLGC 4L2KC 5C5RC 3OEIA 5ADQB 3CTOA 4UI5C 4UI7C 5C5QC 4HLFC 2ZIXB 5C5PC 4ZLXA 4HLHC 5FPFC 4L33C 3KH2E 4HKIC 4HKKB 4L10C 3HRYA 4L2GC 4UVPB 3HJ6A 5ADTB
chains in the Genus database with same CATH topology
4HMHC 4HL5C 4L0VC 4L32C 4L31C 4L0SC 4UI3C 4HLKC 4L2FC 4KZUC 4UI4C 4HKNC 4KZLC 5ADRB 4L0TC 4UI6C 5ADSB 4KZQC 4L0IC 4L09C 4UI8C 4HLMC 4L34C 4L0BC 4HLGC 4L2KC 5C5RC 5ADQB 4UI5C 4UI7C 5C5QC 4HLFC 2ZIXB 5C5PC 4HLHC 5FPFC 4L33C 4HKIC 4HKKB 4L10C 4L2GC 4UVPB 3HJ6A 5ADTB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HMH C;  4HL5 C;  4L0V C;  4L32 C;  4L31 C;  4L0S C;  4UI3 C;  4HLK C;  4L2F C;  4KZU C;  4UI4 C;  4HKN C;  4KZL C;  5ADR B;  4L0T C;  4UI6 C;  5ADS B;  4KZQ C;  4L0I C;  4L09 C;  4UI8 C;  4HLM C;  4L34 C;  4L0B C;  4HLG C;  4L2K C;  5ADQ B;  4UI5 C;  4UI7 C;  5C5Q C;  4HLF C;  5C5P C;  4HLH C;  5FPF C;  4L33 C;  4HKI C;  4HKK B;  4L10 C;  4L2G C;  4UVP B;  5C5R C;  5ADT B; 
#chains in the Genus database with same CATH topology
 4HMH C;  3K33 B;  4HL5 C;  4ZM0 A;  4L0V C;  2ODK A;  3OEI E;  2A6Q A;  3G5O A;  4L31 C;  4L0S C;  4L32 C;  4HLK C;  4UI3 C;  3D55 A;  4ZM2 A;  4L2F C;  4KZU C;  4UI4 C;  4HKN C;  4KZL C;  3K6Q A;  5ADR B;  4L0T C;  4UI6 C;  5ADS B;  4KZQ C;  4L0I C;  4L09 C;  4UI8 C;  4HLM C;  4L34 C;  3HS2 A;  4L0B C;  4HLG C;  4L2K C;  5C5R C;  3OEI A;  5ADQ B;  3CTO A;  4UI5 C;  4UI7 C;  5C5Q C;  4HLF C;  2ZIX B;  5C5P C;  4ZLX A;  4HLH C;  5FPF C;  4L33 C;  3KH2 E;  4HKI C;  4HKK B;  4L10 C;  3HRY A;  4L2G C;  4UVP B;  3HJ6 A;  5ADT B; 
#chains in the Genus database with same CATH homology
 4HMH C;  4HL5 C;  4L0V C;  4L32 C;  4L31 C;  4L0S C;  4UI3 C;  4HLK C;  4L2F C;  4KZU C;  4UI4 C;  4HKN C;  4KZL C;  5ADR B;  4L0T C;  4UI6 C;  5ADS B;  4KZQ C;  4L0I C;  4L09 C;  4UI8 C;  4HLM C;  4L34 C;  4L0B C;  4HLG C;  4L2K C;  5C5R C;  5ADQ B;  4UI5 C;  4UI7 C;  5C5Q C;  4HLF C;  2ZIX B;  5C5P C;  4HLH C;  5FPF C;  4L33 C;  4HKI C;  4HKK B;  4L10 C;  4L2G C;  4UVP B;  3HJ6 A;  5ADT B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...