4HLGC

Crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Homo sapiens
publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlgC00
4L0IC 4UI3C 5C5QC 4KZQC 4HLKC 4UVPB 4HL5C 4HLFC 4L0VC 4L32C 4HLGC 5ADTB 4UI4C 5C5PC 4KZLC 4UI5C 4L2FC 4UI7C 4L0TC 4L31C 5C5RC 4L0SC 5ADSB 4L34C 4KZUC 5FPFC 4L0BC 4L2GC 4L10C 4HKIC 4L09C 4UI6C 5ADQB 4UI8C 4HMHC 4L33C 4L2KC 5ADRB 4HKNC 4HLMC 4HLHC 4HKKB
chains in the Genus database with same CATH superfamily
3HRYA 4L0IC 4UI3C 5C5QC 4KZQC 4HLKC 4UVPB 4HL5C 4HLFC 4L0VC 4L32C 4HLGC 5ADTB 3D55A 4UI4C 5C5PC 4KZLC 4UI5C 4L2FC 3HS2A 4UI7C 4L0TC 3CTOA 2ZIXB 4L31C 3G5OA 3HJ6A 5C5RC 4L0SC 5ADSB 4L34C 4ZM2A 4KZUC 5FPFC 4L0BC 4L2GC 4L10C 5ADQB 4HKIC 4ZM0A 4L09C 3K6QA 2ODKA 4UI6C 4HMHC 4L33C 4L2KC 4UI8C 4HKNC 4ZLXA 5ADRB 3OEIA 4HLMC 3KH2E 3K33B 4HLHC 2A6QA 3OEIE 4HKKB
chains in the Genus database with same CATH topology
4L0IC 4UI3C 5C5QC 4KZQC 4HLKC 4UVPB 4HL5C 4HLFC 4L0VC 4L32C 4HLGC 5ADTB 4UI4C 5C5PC 4KZLC 4UI5C 4L2FC 4UI7C 4L0TC 2ZIXB 4L31C 3HJ6A 5C5RC 4L0SC 5ADSB 4L34C 4KZUC 5FPFC 4L0BC 4L2GC 4L10C 4HKIC 4L09C 4UI6C 5ADQB 4UI8C 4HMHC 4L33C 4L2KC 5ADRB 4HKNC 4HLMC 4HLHC 4HKKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L0I C;  4UI3 C;  5C5Q C;  4KZQ C;  4HLK C;  4UVP B;  4HL5 C;  4HLF C;  4L0V C;  4L32 C;  4HLG C;  5ADT B;  4UI4 C;  5C5P C;  4KZL C;  4UI5 C;  4L2F C;  4UI7 C;  4L0T C;  4L31 C;  5C5R C;  4L0S C;  5ADS B;  4L34 C;  4KZU C;  5FPF C;  4L0B C;  4L2G C;  4L10 C;  4HKI C;  4L09 C;  4UI6 C;  5ADQ B;  4UI8 C;  4HMH C;  4L33 C;  4L2K C;  5ADR B;  4HKN C;  4HLM C;  4HLH C;  4HKK B; 
#chains in the Genus database with same CATH topology
 3HRY A;  4L0I C;  4UI3 C;  5C5Q C;  4KZQ C;  4HLK C;  4UVP B;  4HL5 C;  4HLF C;  4L0V C;  4L32 C;  4HLG C;  5ADT B;  3D55 A;  4UI4 C;  5C5P C;  4KZL C;  4UI5 C;  4L2F C;  3HS2 A;  4UI7 C;  4L0T C;  3CTO A;  2ZIX B;  4L31 C;  3G5O A;  3HJ6 A;  5C5R C;  4L0S C;  5ADS B;  4L34 C;  4ZM2 A;  4KZU C;  5FPF C;  4L0B C;  4L2G C;  4L10 C;  5ADQ B;  4HKI C;  4ZM0 A;  4L09 C;  3K6Q A;  2ODK A;  4UI6 C;  4HMH C;  4L33 C;  4L2K C;  4UI8 C;  4HKN C;  4ZLX A;  5ADR B;  3OEI A;  4HLM C;  3KH2 E;  3K33 B;  4HLH C;  2A6Q A;  3OEI E;  4HKK B; 
#chains in the Genus database with same CATH homology
 4L0I C;  4UI3 C;  5C5Q C;  4KZQ C;  4HLK C;  4UVP B;  4HL5 C;  4HLF C;  4L0V C;  4L32 C;  4HLG C;  5ADT B;  4UI4 C;  5C5P C;  4KZL C;  4UI5 C;  4L2F C;  4UI7 C;  4L0T C;  2ZIX B;  4L31 C;  3HJ6 A;  5C5R C;  4L0S C;  5ADS B;  4L34 C;  4KZU C;  5FPF C;  4L0B C;  4L2G C;  4L10 C;  4HKI C;  4L09 C;  4UI6 C;  5ADQ B;  4UI8 C;  4HMH C;  4L33 C;  4L2K C;  5ADR B;  4HKN C;  4HLM C;  4HLH C;  4HKK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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