4HLHC

Crystal structure of tankyrase 2 in complex with 4'-fluoroflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Homo sapiens
publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlhC00
4L34C 5FPFC 4HLFC 4UI7C 4UI5C 5C5QC 4UI4C 5ADRB 5C5PC 4UVPB 4HL5C 4HKKB 4UI8C 5ADSB 4L0TC 5ADTB 4KZUC 5C5RC 4L2GC 4L31C 4L2FC 4L0BC 4UI3C 4L09C 4HLMC 4L0IC 4HLGC 4L2KC 4HLKC 4HKNC 4KZLC 4HMHC 4HKIC 4L0VC 4L33C 5ADQB 4L32C 4UI6C 4KZQC 4HLHC 4L10C 4L0SC
chains in the Genus database with same CATH superfamily
4L34C 5FPFC 4HLFC 2ODKA 4UI7C 4UI5C 3CTOA 5C5QC 4UI4C 3HRYA 5ADRB 5C5PC 4UVPB 4HL5C 4ZLXA 3G5OA 4HKKB 4UI8C 3D55A 5ADSB 4L0TC 3HS2A 4KZUC 5ADTB 3OEIA 5C5RC 4ZM2A 4L2GC 4L31C 4L2FC 4L0BC 2A6QA 4UI3C 3KH2E 4L09C 4ZM0A 4HLMC 4L0IC 4HLGC 4L2KC 4HLKC 4HKNC 4KZLC 2ZIXB 4HKIC 4HMHC 3OEIE 4L0VC 4L33C 5ADQB 4L32C 4UI6C 3K33B 4KZQC 3HJ6A 4HLHC 3K6QA 4L10C 4L0SC
chains in the Genus database with same CATH topology
4L34C 5FPFC 4HLFC 4UI7C 4UI5C 5C5QC 4UI4C 5ADRB 5C5PC 4UVPB 4HL5C 4HKKB 4UI8C 5ADSB 4L0TC 5ADTB 4KZUC 5C5RC 4L2GC 4L31C 4L2FC 4L0BC 4UI3C 4L09C 4HLMC 4L0IC 4HLGC 4L2KC 4HLKC 4HKNC 4KZLC 2ZIXB 4HKIC 4HMHC 4L0VC 4L33C 5ADQB 4L32C 4UI6C 4KZQC 3HJ6A 4HLHC 4L10C 4L0SC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L34 C;  5FPF C;  4HLF C;  4UI7 C;  4UI5 C;  5C5Q C;  4UI4 C;  5ADR B;  5C5P C;  4UVP B;  4HL5 C;  4HKK B;  4UI8 C;  5ADS B;  4L0T C;  5ADT B;  4KZU C;  5C5R C;  4L2G C;  4L31 C;  4L2F C;  4L0B C;  4UI3 C;  4L09 C;  4HLM C;  4L0I C;  4HLG C;  4L2K C;  4HLK C;  4HKN C;  4KZL C;  4HMH C;  4HKI C;  4L0V C;  4L33 C;  5ADQ B;  4L32 C;  4UI6 C;  4KZQ C;  4HLH C;  4L10 C;  4L0S C; 
#chains in the Genus database with same CATH topology
 4L34 C;  5FPF C;  4HLF C;  2ODK A;  4UI7 C;  4UI5 C;  3CTO A;  5C5Q C;  4UI4 C;  3HRY A;  5ADR B;  5C5P C;  4UVP B;  4HL5 C;  4ZLX A;  3G5O A;  4HKK B;  4UI8 C;  3D55 A;  5ADS B;  4L0T C;  3HS2 A;  4KZU C;  5ADT B;  3OEI A;  5C5R C;  4ZM2 A;  4L2G C;  4L31 C;  4L2F C;  4L0B C;  2A6Q A;  4UI3 C;  3KH2 E;  4L09 C;  4ZM0 A;  4HLM C;  4L0I C;  4HLG C;  4L2K C;  4HLK C;  4HKN C;  4KZL C;  2ZIX B;  4HKI C;  4HMH C;  3OEI E;  4L0V C;  4L33 C;  5ADQ B;  4L32 C;  4UI6 C;  3K33 B;  4KZQ C;  3HJ6 A;  4HLH C;  3K6Q A;  4L10 C;  4L0S C; 
#chains in the Genus database with same CATH homology
 4L34 C;  5FPF C;  4HLF C;  4UI7 C;  4UI5 C;  5C5Q C;  4UI4 C;  5ADR B;  5C5P C;  4UVP B;  4HL5 C;  4HKK B;  4UI8 C;  5ADS B;  4L0T C;  5ADT B;  4KZU C;  5C5R C;  4L2G C;  4L31 C;  4L2F C;  4L0B C;  4UI3 C;  4L09 C;  4HLM C;  4L0I C;  4HLG C;  4L2K C;  4HLK C;  4HKN C;  4KZL C;  2ZIX B;  4HKI C;  4HMH C;  4L0V C;  4L33 C;  5ADQ B;  4L32 C;  4UI6 C;  4KZQ C;  3HJ6 A;  4HLH C;  4L10 C;  4L0S C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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