4HLHC

Crystal structure of tankyrase 2 in complex with 4'-fluoroflavone
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlhC00
4HLFC 4L09C 4UI5C 5ADSB 4L2GC 5ADTB 4L31C 4HLKC 4UVPB 4KZQC 4L0BC 4KZLC 4L0SC 4L2FC 4L33C 5C5QC 4HLGC 4UI8C 4L0IC 4UI3C 5C5RC 4HLHC 5FPFC 4L0VC 4HKIC 5C5PC 4L2KC 5ADRB 4HKNC 4UI7C 4HLMC 4UI6C 4HMHC 4HKKB 4L0TC 4L34C 4L32C 4KZUC 5ADQB 4UI4C 4L10C 4HL5C
chains in the Genus database with same CATH superfamily
4HLFC 3KH2E 3D55A 4ZM0A 3K33B 3HRYA 4L09C 4UI5C 5ADSB 4ZLXA 4L2GC 5ADTB 4L31C 4HLKC 4UVPB 4KZQC 4L0BC 2A6QA 4KZLC 4L0SC 4L33C 4L2FC 5C5QC 4HLGC 2ODKA 3K6QA 4UI8C 4L0IC 4UI3C 5C5RC 4HLHC 5FPFC 2ZIXB 4L0VC 3OEIE 4HKIC 5C5PC 3HJ6A 4L2KC 5ADRB 4UI7C 4HLMC 4UI6C 4HMHC 4HKKB 4L0TC 3HS2A 4L34C 4L32C 3G5OA 4KZUC 5ADQB 3CTOA 4L10C 4UI4C 3OEIA 4HKNC 4ZM2A 4HL5C
chains in the Genus database with same CATH topology
4HLFC 4L09C 4UI5C 5ADSB 4L2GC 5ADTB 4L31C 4HLKC 4UVPB 4KZQC 4L0BC 4KZLC 4L0SC 4L2FC 4L33C 5C5QC 4HLGC 4UI8C 4L0IC 4UI3C 5C5RC 4HLHC 5FPFC 4L0VC 2ZIXB 4HKIC 5C5PC 3HJ6A 4L2KC 5ADRB 4UI7C 4HLMC 4UI6C 4HMHC 4HKKB 4L0TC 4L34C 4L32C 4KZUC 5ADQB 4L10C 4UI4C 4HKNC 4HL5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HLF C;  4L09 C;  4UI5 C;  5ADS B;  4L2G C;  5ADT B;  4L31 C;  4HLK C;  4UVP B;  4KZQ C;  4L0B C;  4KZL C;  4L0S C;  4L2F C;  4L33 C;  5C5Q C;  4HLG C;  4UI8 C;  4L0I C;  4UI3 C;  5C5R C;  4HLH C;  5FPF C;  4L0V C;  4HKI C;  5C5P C;  4L2K C;  5ADR B;  4HKN C;  4UI7 C;  4HLM C;  4UI6 C;  4HMH C;  4HKK B;  4L0T C;  4L34 C;  4L32 C;  4KZU C;  5ADQ B;  4UI4 C;  4L10 C;  4HL5 C; 
#chains in the Genus database with same CATH topology
 4HLF C;  3KH2 E;  3D55 A;  4ZM0 A;  3K33 B;  3HRY A;  4L09 C;  4UI5 C;  5ADS B;  4ZLX A;  4L2G C;  5ADT B;  4L31 C;  4HLK C;  4UVP B;  4KZQ C;  4L0B C;  2A6Q A;  4KZL C;  4L0S C;  4L33 C;  4L2F C;  5C5Q C;  4HLG C;  2ODK A;  3K6Q A;  4UI8 C;  4L0I C;  4UI3 C;  5C5R C;  4HLH C;  5FPF C;  2ZIX B;  4L0V C;  3OEI E;  4HKI C;  5C5P C;  3HJ6 A;  4L2K C;  5ADR B;  4UI7 C;  4HLM C;  4UI6 C;  4HMH C;  4HKK B;  4L0T C;  3HS2 A;  4L34 C;  4L32 C;  3G5O A;  4KZU C;  5ADQ B;  3CTO A;  4L10 C;  4UI4 C;  3OEI A;  4HKN C;  4ZM2 A;  4HL5 C; 
#chains in the Genus database with same CATH homology
 4HLF C;  4L09 C;  4UI5 C;  5ADS B;  4L2G C;  5ADT B;  4L31 C;  4HLK C;  4UVP B;  4KZQ C;  4L0B C;  4KZL C;  4L0S C;  4L2F C;  4L33 C;  5C5Q C;  4HLG C;  4UI8 C;  4L0I C;  4UI3 C;  5C5R C;  4HLH C;  5FPF C;  4L0V C;  2ZIX B;  4HKI C;  5C5P C;  3HJ6 A;  4L2K C;  5ADR B;  4UI7 C;  4HLM C;  4UI6 C;  4HMH C;  4HKK B;  4L0T C;  4L34 C;  4L32 C;  4KZU C;  5ADQ B;  4L10 C;  4UI4 C;  4HKN C;  4HL5 C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...