4HLKC

Crystal structure of tankyrase 2 in complex with 4'-methylflavone
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
molecule keywords Tankyrase-2
molecule tags Transferase
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hlkC00
4KZLC 4UI5C 4L0VC 4HLMC 4L31C 4L34C 4L0IC 4L2GC 4L09C 4HL5C 5ADTB 4L0TC 5ADSB 4KZQC 4L10C 4L0SC 4UI6C 4HKKB 4HMHC 4UVPB 4L2FC 4HLKC 4L33C 5C5QC 5C5RC 4UI7C 4HLFC 4UI8C 4L32C 5FPFC 4HKNC 4HLGC 4KZUC 5C5PC 4UI3C 4HLHC 4UI4C 5ADRB 4L0BC 4L2KC 5ADQB 4HKIC
chains in the Genus database with same CATH superfamily
4KZLC 2ODKA 4UI5C 4L0VC 3KH2E 4HLMC 4L31C 4L34C 4L0IC 4L2GC 4ZM0A 4L09C 4HL5C 5ADTB 4L0TC 5ADSB 3CTOA 4ZLXA 4KZQC 4L10C 4L0SC 4UI6C 3HS2A 4HKKB 4HMHC 4UVPB 3OEIE 4HLKC 4L33C 4L2FC 4ZM2A 5C5QC 3OEIA 5C5RC 4UI7C 4HLFC 4UI8C 3K33B 4L32C 5FPFC 4HKNC 4HLGC 4KZUC 5C5PC 3D55A 4UI3C 4HLHC 3HJ6A 4UI4C 2ZIXB 3K6QA 5ADRB 4L0BC 3HRYA 2A6QA 4L2KC 5ADQB 3G5OA 4HKIC
chains in the Genus database with same CATH topology
4KZLC 4UI5C 4L0VC 4HLMC 4L31C 4L34C 4L0IC 4L2GC 4L09C 4HL5C 5ADTB 4L0TC 5ADSB 4KZQC 4L10C 4L0SC 4UI6C 4HKKB 4HMHC 4UVPB 4L2FC 4HLKC 4L33C 5C5QC 5C5RC 4UI7C 4HLFC 4UI8C 4L32C 5FPFC 4HKNC 4HLGC 4KZUC 5C5PC 4UI3C 4HLHC 3HJ6A 4UI4C 2ZIXB 5ADRB 4L0BC 4L2KC 5ADQB 4HKIC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KZL C;  4UI5 C;  4L0V C;  4HLM C;  4L31 C;  4L34 C;  4L0I C;  4L2G C;  4L09 C;  4HL5 C;  5ADT B;  4L0T C;  5ADS B;  4KZQ C;  4L10 C;  4L0S C;  4UI6 C;  4HKK B;  4HMH C;  4UVP B;  4L2F C;  4HLK C;  4L33 C;  5C5Q C;  5C5R C;  4UI7 C;  4HLF C;  4UI8 C;  4L32 C;  5FPF C;  4HKN C;  4HLG C;  4KZU C;  5C5P C;  4UI3 C;  4HLH C;  4UI4 C;  5ADR B;  4L0B C;  4L2K C;  5ADQ B;  4HKI C; 
#chains in the Genus database with same CATH topology
 4KZL C;  2ODK A;  4UI5 C;  4L0V C;  3KH2 E;  4HLM C;  4L31 C;  4L34 C;  4L0I C;  4L2G C;  4ZM0 A;  4L09 C;  4HL5 C;  5ADT B;  4L0T C;  5ADS B;  3CTO A;  4ZLX A;  4KZQ C;  4L10 C;  4L0S C;  4UI6 C;  3HS2 A;  4HKK B;  4HMH C;  4UVP B;  3OEI E;  4HLK C;  4L33 C;  4L2F C;  4ZM2 A;  5C5Q C;  3OEI A;  5C5R C;  4UI7 C;  4HLF C;  4UI8 C;  3K33 B;  4L32 C;  5FPF C;  4HKN C;  4HLG C;  4KZU C;  5C5P C;  3D55 A;  4UI3 C;  4HLH C;  3HJ6 A;  4UI4 C;  2ZIX B;  3K6Q A;  5ADR B;  4L0B C;  3HRY A;  2A6Q A;  4L2K C;  5ADQ B;  3G5O A;  4HKI C; 
#chains in the Genus database with same CATH homology
 4KZL C;  4UI5 C;  4L0V C;  4HLM C;  4L31 C;  4L34 C;  4L0I C;  4L2G C;  4L09 C;  4HL5 C;  5ADT B;  4L0T C;  5ADS B;  4KZQ C;  4L10 C;  4L0S C;  4UI6 C;  4HKK B;  4HMH C;  4UVP B;  4L2F C;  4HLK C;  4L33 C;  5C5Q C;  5C5R C;  4UI7 C;  4HLF C;  4UI8 C;  4L32 C;  5FPF C;  4HKN C;  4HLG C;  4KZU C;  5C5P C;  4UI3 C;  4HLH C;  3HJ6 A;  4UI4 C;  2ZIX B;  5ADR B;  4L0B C;  4L2K C;  5ADQ B;  4HKI C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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