4KN4E

X-ray crystal structure of the escherichia coli rna polymerase in complex with benzoxazinorifamycin-2b
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
90
structure length
90
Chain Sequence
ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
pubmed doi rcsb
molecule tags Transferase/antibiotic
source organism Escherichia coli
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 23
structure length 90
sequence length 90
chains with identical sequence J
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2013-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 4kn4E00
4OINE 1SFOF 2JA8F 4C3HF 4A3JF 2R93F 3S17F 4YG2E 4KMUE 2Y0SI 1I3QF 4BBRF 3CQZF 4AYBK 4Q5SE 5C44F 2BE5E 3I4NF 4A3BF 4A3IF 3HKZK 3K7AF 5TMFE 4C3JF 4C2MF 5C4JF 1Y1VF 4XLNE 5M5YF 3S1QF 3I4MF 1I50F 5FLMF 4Y7NF 5D4EE 2PPBE 3HOXF 3S14F 5IYBF 5IP7F 4LK0E 5E18E 3EQLE 2WAQK 4A3LF 3H3VG 4A3FF 5BYHE 1QKLA 2NVYF 5FJ8F 1ZYRE 3DXJE 2NVXF 3GTLF 3S15F 3S1NF 1SMYE 5M5WF 2JA6F 4A3CF 3M4OF 4JK1E 3S16F 2PMZK 4ZH4E 5C3EF 3GTOF 1Y1WF 2NVQF 1TWHF 2A6EE 2R92F 4X6AF 4C3IF 3H0GF 5M3FF 2R7ZF 4G7ZE 4MQ9E 1YNJK 2A69E 3GTPF 3HOVF 4A3KF 4OIRE 4GZYE 4LJZE 4G7OE 4BBSF 4XLPE 3HOWF 2B63F 4OIPE 5M5XF 5M3MF 4MEYE 5C4XF 4YFKE 2YU9F 1YNNK 2CW0E 5IP9F 4YFNE 2O5JE 5IYCF 1TWGF 1IW7E 3HOUF 1I6VE 2A6HE 3GTKF 2E2IF 1K83F 1TWFF 3M3YF 2E2JF 2A68E 4BY7F 4Q4ZE 4A3EF 2E2HF 4MEXE 3GTJF 3PO2F 4XSZE 1WCMF 2JA7F 4A93F 3HOYF 4A3GF 3S2DF 3HOZF 1I6HF 3GTQF 4A3DF 3RZOF 1R9TF 3GTMF 1HQME 2NVTF 4KN7E 3S1RF 1TWAF 4OIOE 2O5IE 3S1MF 4LK1E 4Y52F 2VUMF 4YFXE 2JA5F 3S2HF 5IYDF 4KN4E 5D4DE 4XSXE 5TMCE 2WB1I 4BY1F 4LLGE 1TWCF 3PO3F 4BXXF 5E17E 5D4CE 4OIQE 5IPLE 3RZDF 3FKIF 4A3MF 3GTGF 4G7HE 3WODE
chains in the Genus database with same CATH superfamily
2NVYE 4OINE 5C4XE 1SFOF 3S15E 3GTLE 2JA8F 4C3HF 4A3JF 2R93F 5M5WE 4YG2E 4KMUE 3S17F 2Y0SI 1I3QF 4BBRF 3HOUE 3CQZF 4AYBK 4Q5SE 5C44F 2BE5E 2PMZH 4AYBH 4A3IF 3I4NF 4A3BF 3HKZK 1K83E 1TWFE 3K7AF 5TMFE 2E2IE 3M3YE 4C3JF 4C2MF 5C4JF 4A3EE 1Y1VF 4A3MF 4XLNE 2E2HE 5M5YF 3GTJE 3S1QF 4A3KE 3H3VF 3I4MF 1I50F 1WCME 4Y7NF 5FLMF 2JA7E 5D4EE 2PPBE 3HOXF 4BBSE 3HOWE 3S14F 5IYBF 5IP7F 2B63E 1I6HE 4LK0E 5E18E 3EQLE 4QIWH 2WAQK 5M3ME 5FJ8E 3H3VG 3GTQE 4A3FF 4A3LF 4A3DE 5BYHE 1QKLA 2NVYF 5FJ8F 1ZYRE 3DXJE 2NVXF 2YU9E 3GTLF 3GTME 3S15F 2NVTE 1SMYE 5IP9E 5M5WF 2JA6F 5IYCE 1TWGE 3S1RE 4A3CF 3M4OF 4JK1E 3S16F 2PMZK 4ZH4E 5C3EF 1TWAE 3GTOF 1Y1WF 2NVQF 3GTKE 1TWHF 2A6EE 2E2JE 2R92F 4BY7E 4C3IF 4X6AF 1EIKA 2JA5E 3S2HE 3H0GF 5IYDE 5M3FF 2R7ZF 4G7ZE 4MQ9E 1YNJK 2A69E 3GTPF 3HOVF 3PO2E 4A3KF 4OIRE 4GZYE 4LJZE 3PO3E 4BXXE 4G7OE 3WODE 4BBSF 4A93E 4XLPE 3RZDE 3HOYE 2WB1H 3FKIE 3HOWF 4A3GE 3GTGE 3S2DE 4Y7NE 3HOZE 2B63F 4OIPE 5M5XF 2JA8E 4QIWK 4C3HE 4A3JE 5M3MF 3S17E 4MEYE 1I3QE 3RZOE 1R9TE 3CQZE 4YFKE 2YU9F 1YNNK 5C44E 3I4NE 5C4XF 4A3IE 2CW0E 5IP9F 4YFNE 2O5JE 5IYCF 1TWGF 1IW7E 4C2ME 3HOUF 2Y0SH 1I6VE 2A6HE 3GTKF 2E2IF 1K83F 1TWFF 3M3YF 2E2JF 3S1ME 2A68E 4BY7F 2VUME 4Q4ZE 4Y52E 4A3EF 2E2HF 1I50E 5FLME 3HOXE 3GTJF 4MEXE 4BY1E 3S14E 3PO2F 1TWCE 2KRXA 5IYBE 4XSZE 1WCMF 2JA7F 4A93F 3HOYF 4A3GF 4A3ME 3S2DF 3HOZF 3S1NE 2NVXE 1I6HF 1SFOE 2R93E 3GTQF 2JA6E 4A3DF 4BBRE 3M4OE 1R9TF 3RZOF 4A3CE 3GTOE 5C3EE 3GTMF 4A3BE 2NVTF 1Y1WE 2NVQE 3K7AE 1TWHE 3HKZH 4KN7E 4C3JE 3S1RF 4C3IE 2R92E 5C4JE 4X6AE 3H0GE 5M3FE 2R7ZE 1TWAF 1DZFA 1Y1VE 5M5YE 4OIOE 2O5IE 3S1NF 3GTPE 4LK1E 3HOVE 3S1MF 4Y52F 2VUMF 4YFXE 3S1QE 2JA5F 3S2HF 5IYDF 4KN4E 5D4DE 3I4ME 4XSXE 5TMCE 3S16E 2WB1I 4BY1F 4LLGE 1TWCF 3PO3F 4BXXF 5E17E 5IP7E 5M5XE 5D4CE 4OIQE 5IPLE 3RZDF 4A3LE 3FKIF 2WAQH 4A3FE 3GTGF 4G7HE 1HQME
chains in the Genus database with same CATH topology
4OINE 1SFOF 2JA8F 4C3HF 4A3JF 2R93F 3S17F 4YG2E 4KMUE 2Y0SI 1I3QF 4BBRF 3CQZF 4AYBK 4Q5SE 5C44F 2BE5E 3I4NF 4A3BF 4A3IF 3HKZK 3K7AF 5TMFE 4C3JF 4C2MF 5C4JF 1Y1VF 4XLNE 5M5YF 3S1QF 3I4MF 1I50F 5FLMF 4Y7NF 5D4EE 2PPBE 3HOXF 3S14F 5IYBF 5IP7F 4LK0E 5E18E 3EQLE 2WAQK 4A3LF 3H3VG 4A3FF 5BYHE 1QKLA 2NVYF 5FJ8F 1ZYRE 3DXJE 2NVXF 3GTLF 3S15F 3S1NF 1SMYE 5M5WF 2JA6F 4A3CF 3M4OF 4JK1E 3S16F 2PMZK 4ZH4E 5C3EF 3GTOF 1Y1WF 2NVQF 1TWHF 2A6EE 2R92F 4X6AF 4C3IF 3H0GF 5M3FF 2R7ZF 4G7ZE 4MQ9E 1YNJK 2A69E 3GTPF 3HOVF 4A3KF 4OIRE 4GZYE 4LJZE 4G7OE 4BBSF 4XLPE 3HOWF 2B63F 4OIPE 5M5XF 4QIWK 5M3MF 4MEYE 5C4XF 4YFKE 2YU9F 1YNNK 2CW0E 5IP9F 4YFNE 2O5JE 5IYCF 1TWGF 1IW7E 3HOUF 1I6VE 2A6HE 3GTKF 2E2IF 1K83F 1TWFF 3M3YF 2E2JF 2A68E 4BY7F 4Q4ZE 4A3EF 2E2HF 4MEXE 3GTJF 3PO2F 2KRXA 4XSZE 1WCMF 2JA7F 4A93F 3HOYF 4A3GF 3S2DF 3HOZF 1I6HF 3GTQF 4A3DF 3RZOF 1R9TF 3GTMF 1HQME 2NVTF 4KN7E 3S1RF 1TWAF 4OIOE 2O5IE 3S1MF 4LK1E 4Y52F 2VUMF 4YFXE 2JA5F 3S2HF 5IYDF 4KN4E 5D4DE 4XSXE 5TMCE 2WB1I 4BY1F 4LLGE 1TWCF 3PO3F 4BXXF 5E17E 5D4CE 4OIQE 5IPLE 3RZDF 3FKIF 4A3MF 3GTGF 4G7HE 3WODE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OIN E;  1SFO F;  2JA8 F;  4C3H F;  4A3J F;  2R93 F;  3S17 F;  4YG2 E;  4KMU E;  2Y0S I;  1I3Q F;  4BBR F;  3CQZ F;  4AYB K;  4Q5S E;  5C44 F;  2BE5 E;  3I4N F;  4A3B F;  4A3I F;  3HKZ K;  3K7A F;  5TMF E;  4C3J F;  4C2M F;  5C4J F;  1Y1V F;  4XLN E;  5M5Y F;  3S1Q F;  3I4M F;  1I50 F;  5FLM F;  4Y7N F;  5D4E E;  2PPB E;  3HOX F;  3S14 F;  5IYB F;  5IP7 F;  4LK0 E;  5E18 E;  3EQL E;  2WAQ K;  4A3L F;  3H3V G;  4A3F F;  5BYH E;  1QKL A;  2NVY F;  5FJ8 F;  1ZYR E;  3DXJ E;  2NVX F;  3GTL F;  3S15 F;  3S1N F;  1SMY E;  5M5W F;  2JA6 F;  4A3C F;  3M4O F;  4JK1 E;  3S16 F;  2PMZ K;  4ZH4 E;  5C3E F;  3GTO F;  1Y1W F;  2NVQ F;  1TWH F;  2A6E E;  2R92 F;  4X6A F;  4C3I F;  3H0G F;  5M3F F;  2R7Z F;  4G7Z E;  4MQ9 E;  1YNJ K;  2A69 E;  3GTP F;  3HOV F;  4A3K F;  4OIR E;  4GZY E;  4LJZ E;  4G7O E;  4BBS F;  4XLP E;  3HOW F;  2B63 F;  4OIP E;  5M5X F;  5M3M F;  4MEY E;  5C4X F;  4YFK E;  2YU9 F;  1YNN K;  2CW0 E;  5IP9 F;  4YFN E;  2O5J E;  5IYC F;  1TWG F;  1IW7 E;  3HOU F;  1I6V E;  2A6H E;  3GTK F;  2E2I F;  1K83 F;  1TWF F;  3M3Y F;  2E2J F;  2A68 E;  4BY7 F;  4Q4Z E;  4A3E F;  2E2H F;  4MEX E;  3GTJ F;  3PO2 F;  4XSZ E;  1WCM F;  2JA7 F;  4A93 F;  3HOY F;  4A3G F;  3S2D F;  3HOZ F;  1I6H F;  3GTQ F;  4A3D F;  3RZO F;  1R9T F;  3GTM F;  1HQM E;  2NVT F;  4KN7 E;  3S1R F;  1TWA F;  4OIO E;  2O5I E;  3S1M F;  4LK1 E;  4Y52 F;  2VUM F;  4YFX E;  2JA5 F;  3S2H F;  5IYD F;  4KN4 E;  5D4D E;  4XSX E;  5TMC E;  2WB1 I;  4BY1 F;  4LLG E;  1TWC F;  3PO3 F;  4BXX F;  5E17 E;  5D4C E;  4OIQ E;  5IPL E;  3RZD F;  3FKI F;  4A3M F;  3GTG F;  4G7H E;  3WOD E; 
#chains in the Genus database with same CATH topology
 2NVY E;  4OIN E;  5C4X E;  1SFO F;  3S15 E;  3GTL E;  2JA8 F;  4C3H F;  4A3J F;  2R93 F;  5M5W E;  4YG2 E;  4KMU E;  3S17 F;  2Y0S I;  1I3Q F;  4BBR F;  3HOU E;  3CQZ F;  4AYB K;  4Q5S E;  5C44 F;  2BE5 E;  2PMZ H;  4AYB H;  4A3I F;  3I4N F;  4A3B F;  3HKZ K;  1K83 E;  1TWF E;  3K7A F;  5TMF E;  2E2I E;  3M3Y E;  4C3J F;  4C2M F;  5C4J F;  4A3E E;  1Y1V F;  4A3M F;  4XLN E;  2E2H E;  5M5Y F;  3GTJ E;  3S1Q F;  4A3K E;  3H3V F;  3I4M F;  1I50 F;  1WCM E;  4Y7N F;  5FLM F;  2JA7 E;  5D4E E;  2PPB E;  3HOX F;  4BBS E;  3HOW E;  3S14 F;  5IYB F;  5IP7 F;  2B63 E;  1I6H E;  4LK0 E;  5E18 E;  3EQL E;  4QIW H;  2WAQ K;  5M3M E;  5FJ8 E;  3H3V G;  3GTQ E;  4A3F F;  4A3L F;  4A3D E;  5BYH E;  1QKL A;  2NVY F;  5FJ8 F;  1ZYR E;  3DXJ E;  2NVX F;  2YU9 E;  3GTL F;  3GTM E;  3S15 F;  2NVT E;  1SMY E;  5IP9 E;  5M5W F;  2JA6 F;  5IYC E;  1TWG E;  3S1R E;  4A3C F;  3M4O F;  4JK1 E;  3S16 F;  2PMZ K;  4ZH4 E;  5C3E F;  1TWA E;  3GTO F;  1Y1W F;  2NVQ F;  3GTK E;  1TWH F;  2A6E E;  2E2J E;  2R92 F;  4BY7 E;  4C3I F;  4X6A F;  1EIK A;  2JA5 E;  3S2H E;  3H0G F;  5IYD E;  5M3F F;  2R7Z F;  4G7Z E;  4MQ9 E;  1YNJ K;  2A69 E;  3GTP F;  3HOV F;  3PO2 E;  4A3K F;  4OIR E;  4GZY E;  4LJZ E;  3PO3 E;  4BXX E;  4G7O E;  3WOD E;  4BBS F;  4A93 E;  4XLP E;  3RZD E;  3HOY E;  2WB1 H;  3FKI E;  3HOW F;  4A3G E;  3GTG E;  3S2D E;  4Y7N E;  3HOZ E;  2B63 F;  4OIP E;  5M5X F;  2JA8 E;  4QIW K;  4C3H E;  4A3J E;  5M3M F;  3S17 E;  4MEY E;  1I3Q E;  3RZO E;  1R9T E;  3CQZ E;  4YFK E;  2YU9 F;  1YNN K;  5C44 E;  3I4N E;  5C4X F;  4A3I E;  2CW0 E;  5IP9 F;  4YFN E;  2O5J E;  5IYC F;  1TWG F;  1IW7 E;  4C2M E;  3HOU F;  2Y0S H;  1I6V E;  2A6H E;  3GTK F;  2E2I F;  1K83 F;  1TWF F;  3M3Y F;  2E2J F;  3S1M E;  2A68 E;  4BY7 F;  2VUM E;  4Q4Z E;  4Y52 E;  4A3E F;  2E2H F;  1I50 E;  5FLM E;  3HOX E;  3GTJ F;  4MEX E;  4BY1 E;  3S14 E;  3PO2 F;  1TWC E;  2KRX A;  5IYB E;  4XSZ E;  1WCM F;  2JA7 F;  4A93 F;  3HOY F;  4A3G F;  4A3M E;  3S2D F;  3HOZ F;  3S1N E;  2NVX E;  1I6H F;  1SFO E;  2R93 E;  3GTQ F;  2JA6 E;  4A3D F;  4BBR E;  3M4O E;  1R9T F;  3RZO F;  4A3C E;  3GTO E;  5C3E E;  3GTM F;  4A3B E;  2NVT F;  1Y1W E;  2NVQ E;  3K7A E;  1TWH E;  3HKZ H;  4KN7 E;  4C3J E;  3S1R F;  4C3I E;  2R92 E;  5C4J E;  4X6A E;  3H0G E;  5M3F E;  2R7Z E;  1TWA F;  1DZF A;  1Y1V E;  5M5Y E;  4OIO E;  2O5I E;  3S1N F;  3GTP E;  4LK1 E;  3HOV E;  3S1M F;  4Y52 F;  2VUM F;  4YFX E;  3S1Q E;  2JA5 F;  3S2H F;  5IYD F;  4KN4 E;  5D4D E;  3I4M E;  4XSX E;  5TMC E;  3S16 E;  2WB1 I;  4BY1 F;  4LLG E;  1TWC F;  3PO3 F;  4BXX F;  5E17 E;  5IP7 E;  5M5X E;  5D4C E;  4OIQ E;  5IPL E;  3RZD F;  4A3L E;  3FKI F;  2WAQ H;  4A3F E;  3GTG F;  4G7H E;  1HQM E; 
#chains in the Genus database with same CATH homology
 4OIN E;  1SFO F;  2JA8 F;  4C3H F;  4A3J F;  2R93 F;  3S17 F;  4YG2 E;  4KMU E;  2Y0S I;  1I3Q F;  4BBR F;  3CQZ F;  4AYB K;  4Q5S E;  5C44 F;  2BE5 E;  3I4N F;  4A3B F;  4A3I F;  3HKZ K;  3K7A F;  5TMF E;  4C3J F;  4C2M F;  5C4J F;  1Y1V F;  4XLN E;  5M5Y F;  3S1Q F;  3I4M F;  1I50 F;  5FLM F;  4Y7N F;  5D4E E;  2PPB E;  3HOX F;  3S14 F;  5IYB F;  5IP7 F;  4LK0 E;  5E18 E;  3EQL E;  2WAQ K;  4A3L F;  3H3V G;  4A3F F;  5BYH E;  1QKL A;  2NVY F;  5FJ8 F;  1ZYR E;  3DXJ E;  2NVX F;  3GTL F;  3S15 F;  3S1N F;  1SMY E;  5M5W F;  2JA6 F;  4A3C F;  3M4O F;  4JK1 E;  3S16 F;  2PMZ K;  4ZH4 E;  5C3E F;  3GTO F;  1Y1W F;  2NVQ F;  1TWH F;  2A6E E;  2R92 F;  4X6A F;  4C3I F;  3H0G F;  5M3F F;  2R7Z F;  4G7Z E;  4MQ9 E;  1YNJ K;  2A69 E;  3GTP F;  3HOV F;  4A3K F;  4OIR E;  4GZY E;  4LJZ E;  4G7O E;  4BBS F;  4XLP E;  3HOW F;  2B63 F;  4OIP E;  5M5X F;  4QIW K;  5M3M F;  4MEY E;  5C4X F;  4YFK E;  2YU9 F;  1YNN K;  2CW0 E;  5IP9 F;  4YFN E;  2O5J E;  5IYC F;  1TWG F;  1IW7 E;  3HOU F;  1I6V E;  2A6H E;  3GTK F;  2E2I F;  1K83 F;  1TWF F;  3M3Y F;  2E2J F;  2A68 E;  4BY7 F;  4Q4Z E;  4A3E F;  2E2H F;  4MEX E;  3GTJ F;  3PO2 F;  2KRX A;  4XSZ E;  1WCM F;  2JA7 F;  4A93 F;  3HOY F;  4A3G F;  3S2D F;  3HOZ F;  1I6H F;  3GTQ F;  4A3D F;  3RZO F;  1R9T F;  3GTM F;  1HQM E;  2NVT F;  4KN7 E;  3S1R F;  1TWA F;  4OIO E;  2O5I E;  3S1M F;  4LK1 E;  4Y52 F;  2VUM F;  4YFX E;  2JA5 F;  3S2H F;  5IYD F;  4KN4 E;  5D4D E;  4XSX E;  5TMC E;  2WB1 I;  4BY1 F;  4LLG E;  1TWC F;  3PO3 F;  4BXX F;  5E17 E;  5D4C E;  4OIQ E;  5IPL E;  3RZD F;  3FKI F;  4A3M F;  3GTG F;  4G7H E;  3WOD E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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