4LIFA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 28
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
127
structure length
127
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Hydrolase, dna binding protein
source organism Jc polyomavirus
total genus 28
structure length 127
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lifA00
4FB3A 2IPRA 4NBPA 4LMDA 2TBDA 4ZQ9A 1L2MA 4ZO0A 2ITLA 3QK2A 1TBDA 2NTCA 5BYGA 2IF9A 4LIFA 1Z1DB 1RZ9A 3QN2A 5DCXA 1L5IA 5D9IA 4FGNA 3QFQA 2NL8A 1M55A 4GDFA 2HW0A 2FUFA 2ITJA 1UUTA 5CYNA
chains in the Genus database with same CATH superfamily
4FB3A 2IPRA 4NBPA 4LMDA 2TBDA 4ZQ9A 1KSYA 1L2MA 4ZO0A 2ITLA 3QK2A 1TBDA 2NTCA 3DKXA 5BYGA 2IF9A 4KW3A 4U87A 4LIFA 1Z1DB 1RZ9A 3QN2A 5DCXA 1L5IA 5D9IA 4FGNA 3QFQA 2NL8A 3DKYA 1M55A 4GDFA 2HW0A 2FUFA 2ITJA 1KSXA 1R9WA 1UUTA 1F08A 5CYNA
chains in the Genus database with same CATH topology
4FB3A 2IPRA 4NBPA 4LMDA 2TBDA 4ZQ9A 1KSYA 1L2MA 4ZO0A 2ITLA 3QK2A 1TBDA 2NTCA 3DKXA 5BYGA 2IF9A 4KW3A 4U87A 4LIFA 1Z1DB 1RZ9A 3QN2A 5DCXA 1L5IA 5D9IA 4FGNA 3QFQA 2NL8A 3DKYA 1M55A 4GDFA 2HW0A 2FUFA 2ITJA 1KSXA 1R9WA 1UUTA 1F08A 5CYNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FB3 A;  2IPR A;  4NBP A;  4LMD A;  2TBD A;  4ZQ9 A;  1L2M A;  4ZO0 A;  2ITL A;  3QK2 A;  1TBD A;  2NTC A;  5BYG A;  2IF9 A;  4LIF A;  1Z1D B;  1RZ9 A;  3QN2 A;  5DCX A;  1L5I A;  5D9I A;  4FGN A;  3QFQ A;  2NL8 A;  1M55 A;  4GDF A;  2HW0 A;  2FUF A;  2ITJ A;  1UUT A;  5CYN A; 
#chains in the Genus database with same CATH topology
 4FB3 A;  2IPR A;  4NBP A;  4LMD A;  2TBD A;  4ZQ9 A;  1KSY A;  1L2M A;  4ZO0 A;  2ITL A;  3QK2 A;  1TBD A;  2NTC A;  3DKX A;  5BYG A;  2IF9 A;  4KW3 A;  4U87 A;  4LIF A;  1Z1D B;  1RZ9 A;  3QN2 A;  5DCX A;  1L5I A;  5D9I A;  4FGN A;  3QFQ A;  2NL8 A;  3DKY A;  1M55 A;  4GDF A;  2HW0 A;  2FUF A;  2ITJ A;  1KSX A;  1R9W A;  1UUT A;  1F08 A;  5CYN A; 
#chains in the Genus database with same CATH homology
 4FB3 A;  2IPR A;  4NBP A;  4LMD A;  2TBD A;  4ZQ9 A;  1KSY A;  1L2M A;  4ZO0 A;  2ITL A;  3QK2 A;  1TBD A;  2NTC A;  3DKX A;  5BYG A;  2IF9 A;  4KW3 A;  4U87 A;  4LIF A;  1Z1D B;  1RZ9 A;  3QN2 A;  5DCX A;  1L5I A;  5D9I A;  4FGN A;  3QFQ A;  2NL8 A;  3DKY A;  1M55 A;  4GDF A;  2HW0 A;  2FUF A;  2ITJ A;  1KSX A;  1R9W A;  1UUT A;  1F08 A;  5CYN A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...