4LMDA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
128
structure length
128
Chain Sequence
EDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Hydrolase
source organism Jc polyomavirus
total genus 38
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lmdA00
1RZ9A 2TBDA 3QK2A 4ZO0A 3QFQA 5DCXA 4LIFA 1M55A 1UUTA 1L5IA 2NTCA 2IPRA 4ZQ9A 4FB3A 1TBDA 2ITJA 4FGNA 4LMDA 5D9IA 2HW0A 2FUFA 3QN2A 4NBPA 1L2MA 2NL8A 5BYGA 1Z1DB 2IF9A 2ITLA 5CYNA 4GDFA
chains in the Genus database with same CATH superfamily
1RZ9A 1KSXA 1KSYA 2TBDA 3QK2A 4ZO0A 3QFQA 5DCXA 4LIFA 1M55A 1UUTA 1L5IA 2NTCA 2IPRA 4ZQ9A 4FB3A 1R9WA 1TBDA 2ITJA 4KW3A 4FGNA 4U87A 4LMDA 5D9IA 2HW0A 2FUFA 3QN2A 1F08A 4NBPA 1L2MA 2NL8A 5BYGA 1Z1DB 2IF9A 3DKXA 5CYNA 2ITLA 4GDFA 3DKYA
chains in the Genus database with same CATH topology
1RZ9A 1KSXA 1KSYA 2TBDA 3QK2A 4ZO0A 3QFQA 5DCXA 4LIFA 1M55A 1UUTA 1L5IA 2NTCA 2IPRA 4ZQ9A 4FB3A 1R9WA 1TBDA 2ITJA 4KW3A 4FGNA 4U87A 4LMDA 5D9IA 2HW0A 2FUFA 3QN2A 1F08A 4NBPA 1L2MA 2NL8A 5BYGA 1Z1DB 2IF9A 3DKXA 5CYNA 2ITLA 4GDFA 3DKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RZ9 A;  2TBD A;  3QK2 A;  4ZO0 A;  3QFQ A;  5DCX A;  4LIF A;  1M55 A;  1UUT A;  1L5I A;  2NTC A;  2IPR A;  4ZQ9 A;  4FB3 A;  1TBD A;  2ITJ A;  4FGN A;  4LMD A;  5D9I A;  2HW0 A;  2FUF A;  3QN2 A;  4NBP A;  1L2M A;  2NL8 A;  5BYG A;  1Z1D B;  2IF9 A;  2ITL A;  5CYN A;  4GDF A; 
#chains in the Genus database with same CATH topology
 1RZ9 A;  1KSX A;  1KSY A;  2TBD A;  3QK2 A;  4ZO0 A;  3QFQ A;  5DCX A;  4LIF A;  1M55 A;  1UUT A;  1L5I A;  2NTC A;  2IPR A;  4ZQ9 A;  4FB3 A;  1R9W A;  1TBD A;  2ITJ A;  4KW3 A;  4FGN A;  4U87 A;  4LMD A;  5D9I A;  2HW0 A;  2FUF A;  3QN2 A;  1F08 A;  4NBP A;  1L2M A;  2NL8 A;  5BYG A;  1Z1D B;  2IF9 A;  3DKX A;  5CYN A;  2ITL A;  4GDF A;  3DKY A; 
#chains in the Genus database with same CATH homology
 1RZ9 A;  1KSX A;  1KSY A;  2TBD A;  3QK2 A;  4ZO0 A;  3QFQ A;  5DCX A;  4LIF A;  1M55 A;  1UUT A;  1L5I A;  2NTC A;  2IPR A;  4ZQ9 A;  4FB3 A;  1R9W A;  1TBD A;  2ITJ A;  4KW3 A;  4FGN A;  4U87 A;  4LMD A;  5D9I A;  2HW0 A;  2FUF A;  3QN2 A;  1F08 A;  4NBP A;  1L2M A;  2NL8 A;  5BYG A;  1Z1D B;  2IF9 A;  3DKX A;  5CYN A;  2ITL A;  4GDF A;  3DKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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