4LMDA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
128
structure length
128
Chain Sequence
EDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Jc polyomavirus
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
molecule keywords Large T antigen
total genus 38
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4lmdA00
2IPRA 1Z1DB 4FB3A 3QN2A 2NTCA 4LIFA 4ZO0A 1L5IA 2TBDA 3QFQA 4ZQ9A 2ITJA 5CYNA 3QK2A 4NBPA 2FUFA 1L2MA 2NL8A 2HW0A 2IF9A 1TBDA 4FGNA 5BYGA 1RZ9A 1UUTA 1M55A 4GDFA 2ITLA 4LMDA 5DCXA 5D9IA
chains in the Genus database with same CATH superfamily
2IPRA 3DKYA 1Z1DB 4FB3A 3QN2A 2NTCA 4LIFA 1L5IA 4ZO0A 2TBDA 3QFQA 4U87A 4ZQ9A 2ITJA 5CYNA 3QK2A 3DKXA 1KSXA 4NBPA 2FUFA 1KSYA 1L2MA 2NL8A 2HW0A 2IF9A 1TBDA 4FGNA 5BYGA 1R9WA 1RZ9A 1UUTA 1M55A 4KW3A 4GDFA 2ITLA 4LMDA 5DCXA 1F08A 5D9IA
chains in the Genus database with same CATH topology
2IPRA 3DKYA 1Z1DB 4FB3A 3QN2A 2NTCA 4LIFA 1L5IA 4ZO0A 2TBDA 3QFQA 4U87A 4ZQ9A 2ITJA 5CYNA 3QK2A 3DKXA 1KSXA 4NBPA 2FUFA 1KSYA 1L2MA 2NL8A 2HW0A 2IF9A 1TBDA 4FGNA 5BYGA 1R9WA 1RZ9A 1UUTA 1M55A 4KW3A 4GDFA 2ITLA 4LMDA 5DCXA 1F08A 5D9IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IPR A;  1Z1D B;  4FB3 A;  3QN2 A;  2NTC A;  4LIF A;  4ZO0 A;  1L5I A;  2TBD A;  3QFQ A;  4ZQ9 A;  2ITJ A;  5CYN A;  3QK2 A;  4NBP A;  2FUF A;  1L2M A;  2NL8 A;  2HW0 A;  2IF9 A;  1TBD A;  4FGN A;  5BYG A;  1RZ9 A;  1UUT A;  1M55 A;  4GDF A;  2ITL A;  4LMD A;  5DCX A;  5D9I A; 
#chains in the Genus database with same CATH topology
 2IPR A;  3DKY A;  1Z1D B;  4FB3 A;  3QN2 A;  2NTC A;  4LIF A;  1L5I A;  4ZO0 A;  2TBD A;  3QFQ A;  4U87 A;  4ZQ9 A;  2ITJ A;  5CYN A;  3QK2 A;  3DKX A;  1KSX A;  4NBP A;  2FUF A;  1KSY A;  1L2M A;  2NL8 A;  2HW0 A;  2IF9 A;  1TBD A;  4FGN A;  5BYG A;  1R9W A;  1RZ9 A;  1UUT A;  1M55 A;  4KW3 A;  4GDF A;  2ITL A;  4LMD A;  5DCX A;  1F08 A;  5D9I A; 
#chains in the Genus database with same CATH homology
 2IPR A;  3DKY A;  1Z1D B;  4FB3 A;  3QN2 A;  2NTC A;  4LIF A;  1L5I A;  4ZO0 A;  2TBD A;  3QFQ A;  4U87 A;  4ZQ9 A;  2ITJ A;  5CYN A;  3QK2 A;  3DKX A;  1KSX A;  4NBP A;  2FUF A;  1KSY A;  1L2M A;  2NL8 A;  2HW0 A;  2IF9 A;  1TBD A;  4FGN A;  5BYG A;  1R9W A;  1RZ9 A;  1UUT A;  1M55 A;  4KW3 A;  4GDF A;  2ITL A;  4LMD A;  5DCX A;  1F08 A;  5D9I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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